Gastric stromal tumors. Presentation of two cases with immunohistochemical study. Review of the literature;Tumeurs stromales gastriques: Presentation de deux cas avec etude immunohistochimique. Revue de la litterature

Journal Medical Libanais

Volumn 50, Issue 5-6, 2002, Pages 226-236

  Kreiker, Joseph ^a,b   Daou, Robert ^c,d   Aftimos, Georges ^b  

^a Saint Joseph Hospital Beirut   (Lebanon)

^b LEBANESE UNIVERSITY   (Lebanon)

^c Service de Chirurgie Generale   (Lebanon)

^d SAINT JOSEPH UNIVERSITY   (Lebanon)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; DESMIN; PROTEIN S 100; STEM CELL FACTOR RECEPTOR;

ADULT; CASE REPORT; COILED BODY; COMPUTER ASSISTED TOMOGRAPHY; ECHOGRAPHY; FEMALE; GASTRECTOMY; GASTROINTESTINAL ENDOSCOPY; GASTROINTESTINAL STROMAL TUMOR; GASTROSCOPY; HISTOGENESIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LIVER BIOPSY; MESENCHYMOMA; PROGNOSIS; PROTEIN EXPRESSION; REVIEW; STOMACH TUMOR; MIDDLE AGED; PATHOLOGY; STROMA CELL;

ADULT; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; PROTO-ONCOGENE PROTEINS C-KIT; S100 PROTEINS; STOMACH NEOPLASMS; STROMAL CELLS;

EID: 1842632566     PISSN: 00239852     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (86)

1. Kim CJ, Day S, Yed KA. Gastrointestinal stromal tumors : analysis of clinical and pathological factors, The American Surgeon, 2001 Feb; 67: 135-7.
2. Miettinen M, Sarlomo-Rikala, Lasota J. Gastrointestinal stromal tumors: Recent advances in understanding of their biology. Hum Pathol 1999 Oct; 30 (10): 1213-20.
3. Balaton AJ, Coindre JM, Cvitkovic F. Tumeurs stromales digestives. Gastroenterol Clin Biol 2001; 25: 473-82.
4. Sava P, Billerey C, Camelot G et al. Les tumeurs myoïdes gastriques: Etude de quatre cas et revue de la littérature. Gastroenterol Clin Biol 1979; 3: 29-36.
5. Lee JSY, Nascimento AG, Farnell MB et al. Epithelioid gastric stromal tumors (Leiomyoblastoma): A study of fifty-five cases. Surgery 1995; 118: 653-61.
6. Rosai J. Stromal tumors. In: Ackerman's Surgical Pathology, 8th édition, St Louis: Mosby, 1996: 645-7.
7. Appelman HD, Helwig EB. Sarcomas of the stomach. Am J Clin Pathol 1977; 67: 2.
8. Appelman H, Helwig E. Cellular leiomyoma of the stomach in 49 patients. Arch Pathol Lab Med 1977; 101: 373-7.
9. Sung Joon Kwon, members of the Korean Gastric Cancer Study Group. Surgery and prognostic factors for gastric stromal tumor. World J Surg 2001; 25: 290-5.
10. Medina-Franco H, El Toum IE, Martin MM, Heslin J. Primary gastrointestinal sarcomas, The American Surgeon 2000 Dec, 66 (12): 1171-5.
11. Strickland L, Letson GD, Muro Cacho CA. Gastrointestinal stromal tumors. JMCC 2001; 8 (3): 252-61.
12. Miettinen M, Monihan JM, Sarlomo-Rikala M et al. Gastrointestinal stromal tumors/smooth muscle tumors (GISTs) primary in the omemtum and mesentery: clinicopathologic and immunohistochemical study of 26 cases. Am J Surg Pathol 1999; 23: 1109-18.
13. Martin JF, Bazin P, Feroldi J, Cabanne F. Tumeurs myoïdes intramurales de l'estomac. Considérations microscopiques. A propos de 6 cas. Ann Anat Pathol 1960; 5: 484-97.
14. Stout AP. Bizarre smooth muscle tumors of the stomach. Cancer 1962; 15: 400-10.
15. Miettinen M. Gastrointestinal stromal tumors; An immunohistochemical study of cellular differentiation. American Journal of Clinical Pathology 1988 May; 89 (5): 601-10.
16. Handra-Luca A, Nahon P, Flejou JF et al. Hétérogé néité immunohistochimique et ultrastructurale des tumeurs stromales digestives. Gastroenterol Clin Biol 2001; 25: 664-8.
17. De Saint Aubin Sommerhausen N, Fletcher CDM. Gastrointestinal stromal tumors: an update. Sarcoma 1998; 2: 133-41.
18. Herrera GA, Pinto de Moraes H, Grizzle WE, Hang SG. Malignant small bowel neoplasm of enteric plexus derivation (plexosarcoma). Light and electron microscopic study confirming the origin of the neoplasm. Dig Dis Sci 1984; 29: 275-84.
19. Newman PL, Wadden C, Fletcher CDM. Gastrointestinal stromal tumors: correlation of immunophenotype with clinicopathological features. J Pathol 1991; 164: 107-17.
20. Lee JR, Joshi V, Griffin JW Jr, Lasota J, Miettinen M. Gastrointestinal autonomic nerve tumor: immunohistochemical and molecular identity with gastrointestinal stromal tumor. Am J Surg Pathol 2001 Aug; 25 (8): 979-87.
21. Basson MD, Modlin IM, Flynn SD. Current clinical and pathologic perspectives on gastric stromal tumors surgery. Gynecology & Obstetrics 1992 Nov; 175: 477-89.
22. Miettinen M, Sarlomo-Rikala M, Lasota J. Gastrointestinal stromal tumors. Ann Chir Gynaecol 1998; 87 (4): 278-81.
23. Mignon F, Julie C, Izzillo R et al. Imaging features of gastric stromal tumors: Radiologic-pathologic correlation. Review of four cases. Journal de Radiologie 2000; 81: 874-81.
24. Bedossa P. Stromal tumors of the digestive tract. Ann Pathol 1997; 17 (Suppl 5): S76-S78.
25. Kindblom LG, Remotti HE, Aldenborg F, Meis-Kindblom JM. Gastrointestinal pacemaker cell tumor (GIPACT): Gastrointestinal stromal tumors show phenotypic characteristics of the interstitial cells of Cajal. Am J Pathol 1998; 152: 1259-69.
26. Miettinen M, Virolainen M, Maarit-Sarlomo-Rikala. Gastrointestinal stromal tumors-value of CD34 antigen in their identification and separation from true leiomyomas and schwannomas. Am J Surg Pathol 1995 Feb; 19 (2): 207-16.
27. Mazur MT, Clark HB. Gastric stromal tumors. Reappraisal of histogenesis. Am J Surg Pathol 1983; 7: 507-19.
28. Hirota S, Isozaki K, Moriyama Y et al. Gain-of-function mutations of C-KIT in human gastrointestinal stromal tumors. Science 1998; 279: 577-80.
29. Sakurai S, Fukasawa T, Chong JM et al. C-KIT gene abnormalities in gastrointestinal stromal tumors (tumors of interstitial cells of Cajal). Jpn J Cancer Res 1999; 90: 1321-8.
30. Miettinen M, Sobin LH, Sarlomo-Rikala M. Immunohistochemical spectrum of GISTs at different sites and their differential diagnosis with a reference to CD117 (KIT). Modern Pathology 2000; 13: 1134-42.
31. Tsujimura T. Role of C-KIT receptor tyrosine kinase in the development, survival and neoplastic transformation of mast cells. Pathol Int 1996; 46: 933-8.
32. Sarlomo-Rikala M, Kovatich AJ, Barusevicius A, Miettinen M. CD117: a sensitive marker for gastrointestinal stromal tumors that is more specific than CD34. Mod Pathol 1998 Aug; 11 (8): 728-34.
33. Lasota J, Wozniak A, Sarlomo-Rikala M et al. Mutations in exons 9 and 13 of KIT gene are rare events in gastrointestinal stromal tumors. A study of 200 cases. Am J Pathol 2000 Oct; 157 (4): 1091-5.
34. Vanderwinden JM, Rumessen JJ, De Laet MH et al. Cd34 + cells in human intestine are fibroblasts adjacent to, but distinct from, interstitial cells of Cajal. Lab Invest 1999; 79: 59-65.
35. Sakurai S, Hihima T, Takazawa Y stromal tumors and KIT-positive mesenchymal cells in the omentum. Pathol Int 2001 Jul; 51 (7): 524-31.
36. Hornick JL, Fletcher CD. Immunohistochemical staining for KIT (CD 117) in soft tissue sarcomas is very limited in distribution. Am J Clin & Pathol 2002 Feb; 117 (2): 188-93.
37. Macaigne G, Boivin JF, Colombu JP et al. Tumeur stromale avec fibres en écheveau de l'intestin grêle révélée par une hémorragie digestive. Gastroenterol Clin Biol 2001 Juin-Juillet; 25 (6-7): 717-19.
38. Miettinen M, Blay JY, Soin LH. Mesenchymal tumors of the stomach. In: Pathology and Genetics of Tumors of the Digestive System, WHO, Lyon: IARC Press, 2000: 62-5.
39. Leborgne J, Jonet D, Le Neel JC, Lenne Y, Malvy P, Deret C. Les tumeurs musculaires gastriques bénignes à propos d'une série chirurgicale de 22 cas. Chirurgie 1988; 114: 405-14.
40. Lerner ME, Farman J, Cho K, Tyler I, Mullen D. Leiomyoblastoma: varied CT appearance. Clin Img 1992; 16: 194-7.
41. Franquemont DW, Frierson HF Jr. Muscle differentiation and clinicopathologic features of gastrointestinal stromal tumors. Am J Surg Pathol 1992; 16: 947-54.
42. Lewin KJ, Appelman HD. Tumors of the esophagus and stomach. In: Atlas of Tumor Pathology, Third Series, Fascicle 18. Washington DC: AFIP, 1995.
43. Debiec-Rychter M, Lasota J, Sarlomo-Rikala M, Kordek R, Miettinen M. Chromosomal aberrations in malignant gastrointestinal stromal tumors: correlation with C-KIT gene mutation. Cancer Genet Cytogenet 2001 Jul 1; 128 (1): 24-30.
44. Lalami E, Cas O, Caumont B, Mur C, Plagnol Ph. Leiomyoblastome de l'estomac: diagnostic et thérapeutique. J Chir 1994; 131: 37-9.
45. Miettinen M, Lasota J. Gastrointestinal stromal tumors -definition, clinical, histological, immunohistochemical and molecular genetic features and differential diagnosis. Virchows Arch 2001 Jan; 438 (1): 1-12.
46. Morgan BK, Compton C, Talbert M, Gallagher WJ, Wood WC. Benign smooth muscle tumors of the gastrointestinal tract, a 24-year experience. Ann Surg 1990 Jan; 211 (1): 63-6.
47. Rogers BB, Grishhaber JE, Mahoney DH, Megill C WW, Wagner ML. Gastric leiomyoblastoma (epithelioid leiomyoma occurring in a child): a case report. Pediatric Pathology 1989; 9 (1): 79-85.
48. Morrissey K, Cho ES, Gray GF, Thorbjarnasson B. Muscular tumors of the stomach. Clinical and pathological study of 113 cases. Ann Surg 1973; 178: 148-55.
49. Davis GB, Blanchard DK, Hatch GF et al. Tumors of the stomach. World J Surg 2000; 24: 412-20.
50. Zerbi A, Braga M, Sironi A, Faravelli A, Di Carlo V. An uncommon cause of massive intraperitoneal bleeding: Leiomyoblastoma of the stomach. Tumori 1988 Jun 30; 74 (3): 365-7.
51. Kelesey JR. Leiomyoblastoma of the stomach presenting as acute intraperitoneal hemorrhage. Gastroenterology 1966; 51: 739-49.
52. Rye BA, Christansen E, Larsen LG. Acute bleeding from leiomyoblastoma of the greater omentum. A case report. Tumori 1989 Jun 30; 75 (3): 296-8.
53. Morgan BK, Compton C, Talbert M, Gallagher WJ, Wood WC. Benign smooth muscle tumors of the gastrointestinal tract - a 24-year experience. Ann Surg Jan 1990; 211 (1): 63-6.
54. Cuilleret J, Baril A, Boucheron S, Pichon A, Serpantie P. Carney's triad. Presse Médicale 1984 Jan 21; 13 (2): 79-82.
55. Mazas-Artasona L, Romeo M, Felices R et al. Gastrooesophageal leiomyoblastoma and multiple pulmonary chondromas: an incomplete variant of Carney's triad. British Journal of Radiology 1998 Dec; 61: 1181-4.
56. Carney JA. The triad of gastric epithelioid leiomyoblastoma, functioning extra adrenal paraganglioma and pulmonary chondroma. Cancer 1979; 43: 374-82.
57. Miettinen M, Sarlomo-Rikala M, Sobin LH, Lasota J. Esophageal stromal tumors: a clinicopathologic, immunohistochemical, and molecular genetic study of 17 cases and comparison with esophageal leiomyomas and leiomyosarcomas. Am J Surg Pathol 2000; 24: 211-22.
58. Hivet M, Lagadec B, Bareau J. Deux tumeurs myoïdes de l'estomac à développement exogastrique. Sem Hop Paris 1972; 48: 2645-51.
59. Aubry P, Lienne P, Alandry G, Jeandel P, Martet G, Zimmerman JM. Leiomyoblastome malin intestinal à double localisation. A propos d'une observation et revue de la littérature. Annales de Médecine Interne (Paris) 1989; 140 (1): 72-4.
60. Shiu MH, Farr GH, Egell RA, Quan SHG, Hadju SI. Myosarcomas of the small and large intestine: a clinicopathologic study. J Surg Oncol 1983; 24: 67-72.
61. Pignon JP, Travers B, Zerbib M et al. Volumineuse tumeur myoïde gastrique. Apports de l'échotomographie et de la tomodensitomé trie. J Radiol 1984; 65: 463-6.
62. Delamarre J, Tossou H, Capron JP, Deschepper B, Sevenet F, Sevestre H. Gastric leiomyoblastoma: diagnosis by CT and ultrasonography. JBR - BTR 1989; 72: 17-20.
63. Firouz Abadie M, Hodonou R, Bonneau A, Adenis-Lamarre P, De Drux J. Leiomyoblastome gastrique. A propos d'un cas et revue de la littérature (lettre). Journal de Chirurgie (Paris) 1989 Oct; 286 (10): 550-1.
64. Hivet M, Lagadec B, Bareau J. Deux tumeurs myoïdes de l'estomac à développement exogastrique. Sem Hop Paris 1972; 48: 2645-51.
65. Malhotra R, Evans R, Bhawan J, Kanzaria P, Silwa W. A malignant gastric leiomyoblastoma presenting as an infected pseudo-cyst of the pancreas. American Journal of Gastroenterology 1988 Apr; 83 (41): 452-6.
66. Slasky BS, Denese L, Skolnick ML. Exogastric leiomyoblastoma : diagnosis by CT and ultrasonography. Southern Medical Journal 1982 Oct; 75 (10): 1275-7.
67. Volk BA, Scholmerieh J, Farthmann E, Gerok W, Wenz W. Leiomyoblastoma of the stomach - a case report on ultrasonographic differential diagnosis of cystic lesions in the abdomen. Hepatogastroenterology 1983 Feb; 30 (1): 33-5.
68. Lerner ME, Farman J, Cho K, Tyler I, Mullen D, Leiomyoblastoma : varied CT appearance. Clin Img 1992; 16: 194-7.
69. Chun HJ, Byun JY, Chun KA et al. Gastrointestinal leiomyoma and leiomyosarcoma: CT differenciation. J Comput Assist Tomogr 1998; 22: 69-74.
70. Palazzo L, Landi B, Cellier C, Cuillerier E, Roseau G, Barbier JP. Endosonographic features predictive of benign and malignant gastrointestinal stromal cell tumors. Gut 2000 Jan; 46 (1): 88-92.
71. Tio TL, Tygat GNJ, Den Hartog Jager. Endoscopic ultrasonography for the evaluation of smooth muscle tumors in the upper gastrointestinal tract: an experience with 42 cases. Gastrointest Endosc 1990; 36: 342.
72. Giovanini M, Seitz JF, Thomas P et al. Echoendoscopie sectorielle électronique en pathologie tumorale bénigne et maligne de l'estomac: résultats chez 30 patients. Gastroenterol Clin Biol 1993; 17: 26.
73. Chak A, Canto ML, Rosch T et al. Endosonographic differentiation of benign and malignant stromal cell tumors. Gastrointest Endosc 1997; 45: 468-73.
74. Delamarre J, Tossou H, Capron JP, Deschepper B, Sevenet F, Sevestre H. Gastric leiomyoblastoma: diagnosis by CT and ultrasonography. JBR - BTR 1989; 72: 17-20.
75. Caletti GC, Brocchi E, Ferrari A et al. Guillotine needle biopsy as a supplement to endosonography in the diagnosis of gastric submucosal tumors. Endoscopy 1991; 23: 251.
76. Letessier E, Courant O, Cuilliere P, Paineau J, Visset J. Léiomyoblastome gastrique: apport de la cytologie. A propos d'un cas. Ann Chir 1992; 46 (3): 258-61.
77. Firouz Abadie M, Sodji M, Alami M, De Brux J. Léiomyome gastrique - à propos de deux cas et revue de la littérature. J Chir (Paris) 1992; 129 (11): 514-6.
78. Payson B, Vasilas A, Gerstmann KE. Spontaneous regression of disseminated gastric leiomyoblastoma. Am J Gastroenterol 1981; 75: 294-8.
79. Van Steen Bergen W, Tojima T, Geboes K et al. Gastric leiomyoblastoma with metastases of the liver. A 36 years following study. Gastroenterology 1985; 89: 875-81.
80. Miller KA, Rubnitz ME, Roth SI. Late recurrence (33 years) of a gastric epithelioid stromal tumor (leiomyblastoma) with low malignant potentiel. Archives of Pathology and Laboratory Medicine 1988 Jan; 112 (1): 86-90.
81. Hideo Baba, Tsutomu Yamada, Takeshi Okamura, Daisuke Korenaga, Keizo Sugimachi, Munetomo Enjoji. Eighteen-year survival of unresected leiomyoblastoma of the stomach with liver and lymph node metastases. European Journal of Surgical Oncology 1989; 15: 159-64.
82. Amin MB, Chan K, Linden MD, Kubus JJ, Zarbo RJ. Prognostic value of proliferating cell nuclear antigen index in gastric stromal tumors. Am J Clin Pathol 1993 Oct; 100 (4): 428-32.
83. Ng EH, Pollock RE, Munsell MF, Atkinson EN, Romsdahl MM. Prognostic factors influencing survival in gastrointestinal leiomyosarcomas: implications for surgical management and staging. Ann Surg 1992; 215: 68.
84. Basso N, Rosato P, De Leo A et al. Laparoscopic treatment of gastric stromal tumors. Surg Endosc 2000 Jun; 14 (6): 524-6.
85. Kaczmarek D, Blanc P, Balique JG, Porcheron J. Métastase sur orifice de trocart après exérèse laparoscopique d'une tumeur stromale du duodénum. Ann Chir 2001; 126: 677-9.
86. Joensuu H, Roberts PJ, Sarlomo-Rikala M et al. Brief report: Effect of the tyrosine kinase inhibitor st1571 in a patient with a metastatic gastrointestinal stromal tumor. N Engl J Med 2001; 344: 1052-6.