A lysosomal tetraspanin associated with retinal degeneration identified via a genome-wide screen

EMBO Journal

Volumn 23, Issue 4, 2004, Pages 811-822

  Xu, Hong ^a   Lee, Seung Jae ^a   Suzuki, Emiko ^b   Dugan, Katherine D ^c   Stoddard, Alexander ^c   Li, Hong Sheng ^a,d   Chodosh, Lewis A ^c   Montell, Craig ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TOKYO   (Japan)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

^d UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

Drosophila; Microarray; Phototransduction; Retinal degeneration; Rhodopsin; Tetraspanin

Indexed keywords

G PROTEIN COUPLED RECEPTOR; MEMBRANE PROTEIN; RHODOPSIN; TETRASPANIN;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DROSOPHILA; GENE EXPRESSION; GENE IDENTIFICATION; GENE MUTATION; LYSOSOME; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOTOTRANSDUCTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FAMILY; PROTEIN LOCALIZATION; RETINA DEGENERATION; SIGNAL TRANSDUCTION; VISUAL SYSTEM;

AMINO ACID SEQUENCE; ANIMALS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; EYE PROTEINS; GENE EXPRESSION REGULATION; LYSOSOMES; MEMBRANE PROTEINS; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR SEQUENCE DATA; MUTATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RETINAL DEGENERATION; RHODOPSIN;

ARACHNIDA; HEXAPODA; MAMMALIA;

EID: 1842614338     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.emboj.7600112     Document Type: Article

References (40)

1. Adams MD, Celniker SE, Holt RA, Evans CA, Gocayne JD, Amanatides PG, Scherer SE, Li PW, Hoskins RA, Galle RF, George RA, Lewis SE, Richards S, Ashburner M, Henderson SN, Sutton GG, Wortman JR, Yandell MD, Zhang Q, Chen LX, Brandon RC, Rogers YH, Blazej RG, Champe M, Pfeiffer BD, Wan KH, Doyle C, Baxter EG, Helt G, Nelson CR, Gabor Miklos GL, Abril JF, Agbayani A, An HJ, Andrews-Pfannkoch C, Baldwin D, Ballew RM, Basu A, Baxendale J, Bayraktaroglu L, Beasley EM, Beeson KY, Benos PV, Berman BP, Bhandari D, Bolshakov S, Borkova D, Botchan MR, Bouck J, Brokstein P, Brottier P, Burtis KC, Busam DA, Butler H, Cadieu E, Center A, Chandra I, Cherry JM, Cawley S, Dahlke C, Davenport LB, Davies P, de Pablos B, Delcher A, Deng Z, Mays AD, Dew I, Deitz SM, Dodson K, Doup LE, Downes M, Dugan-Rocha S, Dunkov BC, Dunn P, Durbin KJ, Evangelista CC, Ferraz C, Ferriera S, Fleischmann W, Fosler C, Gabrielian AE, Garg NS, Gelbart WM, Glasser K, Glodek A, Gong F, Gorrell JH, Gu Z, Guan P, Harris M, Harris NL, Harvey D, Heiman TJ, Hernandez JR, Houck J, Hostin D, Houston KA, Howland TJ, Wei MH, Ibegwam C, Jalali M, Kalush F, Karpen GH, Ke Z, Kennison JA, Ketchum KA, Kimmel BE, Kodira CD, Kraft C, Kravitz S, Kulp D, Lai Z, Lasko P, Lei Y, Levitsky AA, Li J, Li Z, Liang Y, Lin X, Liu X, Mattei B, McIntosh TC, McLeod MP, McPherson D, Merkulov G, Milshina NV, Mobarry C, Morris J, Moshrefi A, Mount SM, Moy M, Murphy B, Murphy L, Muzny DM, Nelson DL, Nelson DR, Nelson KA, Nixon K, Nusskern DR, Pacleb JM, Palazzolo M, Pittman GS, Pan S, Pollard J, Puri V, Reese MG, Reinert K, Remington K, Saunders RD, Scheeler F, Shen H, Shue BC, Siden-Kiamos I, Simpson M, Skupski MP, Smith T, Spier E, Spradling AC, Stapleton M, Strong R, Sun E, Svirskas R, Tector C, Turner R, Venter E, Wang AH, Wang X, Wang ZY, Wassarman DA, Weinstock GM, Weissenbach J, Williams SM, Woodage T, Worley KC, Wu D, Yang S, Yao QA, Ye J, Yeh RF, Zaveri JS, Zhan M, Zhang G, Zhao Q, Zheng L, Zheng XH, Zhong FN, Zhong W, Zhou X, Zhu S, Zhu X, Smith HO, Gibbs RA, Myers EW, Rubin GM, Venter JC (2000) The genome sequence of Drosophila melanogaster. Science 287: 2185-2195
2. Alloway PG, Howard L, Dolph PJ (2000) The formation of stable rhodopsin-arrestin complexes induces apoptosis and photoreceptor cell degeneration. Neuron 28: 129-138
3. Arbeitman MN, Furlong EE, Imam F, Johnson E, Null BH, Baker BS, Krasnow MA, Scott MP, Davis RW, White KP (2002) Gene expression during the life cycle of Drosophila melanogaster. Science 297: 2270-2275
4. Bascom RA, Manara S, Collins L, Molday RS, Kalnins VI, McInnes RR (1992) Cloning of the cDNA for a novel photoreceptor membrane protein (rom-1) identifies a disk rim protein family implicated in human retinopathies. Neuron 8: 1171-1184
5. Blackshaw S, Fraioli RE, Furukawa T, Cepko CL (2001) Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes. Cell 107: 579-589
6. Bloomquist BT, Shortridge RD, Schneuwly S, Perdew M, Montell C, Steller H, Rubin G, Pak WL (1988) Isolation of a putative phospholipase C gene of Drosophila, norpA, and its role in phototransduction. Cell 54: 723-733
7. Bonini NM, Leiserson WM, Benzer S (1998) Multiple roles of the eyes absent gene in Drosophila. Dev Biol 196: 42-57
8. Chevesich J, Kreuz AJ, Montell C (1997) Requirement for the PDZ domain protein, INAD, for localization of the TRP store-operated channel to a signaling complex. Neuron 18: 95-105
9. Claing A, Laporte SA, Caron MG, Lefkowitz RJ (2002) Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and β-arrestin proteins. Prog Neurobiol 66: 61-79
10. Claridge-Chang A, Wijnen H, Naef F, Boothroyd C, Rajewsky N, Young MW (2001) Circadian regulation of gene expression systems in the Drosophila head, Neuron 32: 657-671
11. Dolph PJ, Ranganathan R, Colley NJ, Hardy RW, Socolich M, Zuker CS (1993) Arrestin function in inactivation of G protein-coupled receptor rhodopsin in vivo, Science 260: 1910-1916
12. Ferguson SS (2001) Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev 53: 1-24
13. Franceschini N, Kirschfeld K (1971) Les phénomènes de pseudopupille dans l'oeil composé de Drosophila. Kybertik 9: 159-182
14. Fukuda M (1991) Lysosomal membrane glycoproteins. Structure, biosynthesis, and intracellular trafficking. J Biol Chem 266: 21327-21330
15. Hardie RC (1991) Whole-cell recordings of the light induced current in dissociated Drosophila photoreceptors: evidence for feedback by calcium permeating the light-sensitive channels. Proc R Soc Lond (B) 245: 203-210
16. Hyde DR, Mecklenburg KL, Pollock JA, Vihtelic TS, Benzer S (1990) Twenty Drosophila visual system cDNA clones: one is a homolog of human arrestin. Proc Natl Acad Sci USA 87: 1008-1012
17. Kalidas S, Smith DP (2002) Novel genomic cDNA hybrids produce effective RNA interference in adult Drosophila. Neuron 33: 177-184
18. Kiselev A, Socolich M, Vinos J, Hardy RW, Zuker CS, Ranganathan R (2000) A molecular pathway for light-dependent photoreceptor apoptosis in Drosophila. Neuron 28: 139-152
19. Kopczynski CC, Davis GW, Goodman CS (1996) A neural tetraspanin, encoded by late bloomer, that facilitates synapse formation. Science 271: 1867-1870
20. Kosloff M, Ella N, Joel-Almagor T, Timberg R, Zars TD, Hyde DR, Minke B, Selinger Z (2003) Regulation of light-dependent Gqα translocation and morphological changes in fly photoreceptors. EMBO J 22: 459-468
21. Lee SJ, Xu H, Kang LW, Amzel LM, Montell C (2003) Light adaptation through phosphoinositide-regulated translocation of Drosophila visual arrestin. Neuron 39: 121-132
22. Li HS, Montell C (2000) TRP and the PDZ protein, INAD, form the core complex required for retention of the signalplex in Drosophila photoreceptor cells. J Cell Biol 150: 1411-1422
23. Maecker HT, Todd SC, Levy S (1997) The tetraspanin superfamily: molecular facilitators. FASEB J 11: 428-442
24. McDonald MJ, Rosbash M (2001) Microarray analysis and organization of circadian gene expression in Drosophila. Cell 107: 567-578
25. Minke B, Selinger Z (1992) Intracellular messengers in invertebrate photoreceptors studied in mutant flies. In Neuromethods, Boulton A, Baker G, Taylor C (eds), pp 517-563. Clifton, NJ: The Humana Press Inc.
26. Montell C (1999) Drosophila visual transduction. Ann Rev Cell Dev Biol 15: 231-268
27. Montell C, Rubin GM (1988) The Drosophila ninaC locus encodes two photoreceptor cell specific proteins with domains homologous to protein kinases and the myosin heavy chain head. Cell 52: 757-772
28. Pak WL (1995) Drosophila in vision research. Invest Ophthalmol Vis Sci 36: 2340-2357
29. Penn JS, Anderson RE (1992) Effects of light history on the rat retina. In Progress in Retinal Research, Osborne N, Chader G (eds), Vol. 11, pp 75-98. New York: Pergamon Press
30. Robertson HM, Preston CR, Phillis RW, Johnson-Schlitz DM, Benz WK, Engels WR (1988) A stable genomic source of P element transposase in Drosophila melanogaster. Genetics 118: 461-470
31. Rong YS, Golic KG (2000) Gene targeting by homologous recombination in Drosophila. Science 288: 2013-2018
32. Schaeren-Wiemers N, Gerfin-Moser A (1993) A single protocol to detect transcripts of various types and expression levels in neural tissue and cultured cells: in situ hybridization using digoxigenin-labelled cRNA probes. Histochemistry 100: 431-440
33. Suzuki E, Hirosawa K (1991) Immunoelectron microscopic study of the opsin distribution in the photoreceptor cells of Drosophila melanogaster. J Electron Microsc (Tokyo) 40: 187-192
34. Takeshima H, Komazaki S, Nishi M, lino M, Kangawa K (2000) Junctophilins: a novel family of junctional membrane complex proteins. Mol Cell 6: 11-22
35. Thummel CS, Pirrotta V (1992) New pCaSpeR P element vectors. Dros Info Serv 71: 150
36. Todres E, Nardi JB, Robertson HM (2000) The tetraspanin superfamily in insects. Insect Mol Biol 9: 581-590
37. Travis GH, Sutcliffe JG, Bok D (1991) The retinal degeneration slow (rds) gene product is a photoreceptor disc membrane-associated glycoprotein. Neuron 6: 61-70
38. Tsunoda S, Sun Y, Suzuki E, Zuker C (2001) Independent anchoring and assembly mechanisms of INAD signaling complexes in Drosophila photoreceptors. J Neurosci 21: 150-158
39. Vihtelic TS, Hyde DR, O'Tousa JE (1991) Isolation and characterization of the Drosophila retinal degeneration B (rdgB) gene, Genetics 127: 761-768
40. Xu XZ, Chien F, Butler A, Salkoff L, Montell C (2000) TRPγ, a Drosophila TRP-related subunit, forms a regulated cation channel with TRPL. Neuron 26: 647-657