Transport of 99mTc-MAG3 via rat renal organic anion

Journal of Nuclear Medicine

Volumn 45, Issue 1, 2004, Pages 86-88

  Blaufox, M Donald ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MERTIATIDE TC 99M; ORGANIC ANION TRANSPORTER; POLYCYCLIC AROMATIC HYDROCARBON; DIAGNOSTIC AGENT; POTASSIUM CHANNEL; RECOMBINANT PROTEIN; SODIUM;

IN VITRO STUDY; KIDNEY TUBULE ABSORPTION; NONHUMAN; NOTE; PRIORITY JOURNAL; XENOPUS LAEVIS; ACTIVE TRANSPORT; ANIMAL; CELL CULTURE; ISOTOPE DILUTION ASSAY; METABOLIC CLEARANCE RATE; METABOLISM; OOCYTE; PHYSIOLOGY; RAT; SCINTISCANNING;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; CELLS, CULTURED; METABOLIC CLEARANCE RATE; OOCYTES; POTASSIUM CHANNELS; RADIOISOTOPE DILUTION TECHNIQUE; RATS; RECOMBINANT PROTEINS; SODIUM; TECHNETIUM TC 99M MERTIATIDE; XENOPUS LAEVIS;

EID: 1842592123     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Note

References (17)

1. 99mTc-MAG3 via rat renal organic anion transporter 1. J Nucl Med. 2004;45:80-85.
2. Smith H. The Kidney: Structure and Function in Health and Disease. New York, NY: Oxford University Press; 1951:1049.
3. Cross RJ, Taggart JV. Renal tubular transport: accumulation of p-aminohippurate by rabbit kidney slices. Am J Physiol. 1950;161:181-190.
4. Moller JV, Sheikh MI. Renal organic anion transport system: pharmacological, physiological, and biochemical aspects. Pharmacol Rev. 1983;34:315-358.
5. Pritchard JB, Miller DS. Mechanisms mediating renal secretion of organic anions and cations. Physiol Rev. 1993;73:765-796.
6. Yee CA, Lee HB, Blaufox MD. Tc-99m DMSA renal uptake: influence of biochemical and physiologic factors. J Nucl Med. 1981;22:1054-1058.
7. Fritzberg AR, Kasina S, Eshima D, Johnson DL. Synthesis and biological evaluation of technetium-99m MAG3 as a hippuran replacement. J Nucl Med. 1986;27:111-116.
8. Sekine T, Watanabe N, Hosoyamada M, Kanai Y, Endou H. Expression cloning and characterization of a novel multispecific organic anion transporter. J Biol Chem. 1997;272:18526-18529.
9. Sekine T, Cha SH, Endou H. The multispecific organic anion transporter (OAT) family. Pflugers Arch July. 2000;440:337-350.
10. Sweet DH, Wolff NA, Pritchard JB. Expression cloning and characterization of ROAT1. J Biol Chem. 1997;272:30088-30095.
11. Uchino H, Tamai I, Yamashita K, et al. p-Aminohippuric acid transport at renal apical membrane mediated by human inorganic phosphate transporter NPT1. Biochem Biophys Res Commun. 2000;270.:254-259.
12. Burckhardt G, Bahn A, Wolff NA. Molecular physiology of renal p-aminohippurate secretion. News Physiol Sci. 2001;16:114-118.
13. Lu R, Chan BS, Schuster VL. Cloning of the human kidney PAH transporter: narrow substrate specificity and regulation by protein kinase C. Am J Physiol. 1999;276:F295-F303.
14. Race JE, Grassl SM, Williams WJ, Holtzman EJ. Molecular cloning and characterization of two novel human renal organic anion transporters (hOAT1 and hOAT3). Biochem Biophys Res Commun. 1999;255:508-514.
15. Roch-Ramel F. Renal transport of organic anions. Curr Opin Nephrol Hypertens. 1998;7:517-524.
16. Burckhardt G, Wolff NA, Bahn A. Molecular characterization of the renal organic anion transporter 1. Cell Biochem Biophys. 2002;36:169-174.
17. Lee HB, Blaufox MD. Mechanism of renal concentration of technetium-99m glucoheptonate. J Nucl Med. 1985;26:1308-1313.