Inhibitory effects of Polygonum cuspidatum water extract (PCWE) and its component rasveratrol on acyl-coenzyme A-cholesterol acyltransferase activity for cholesteryl ester synthesis in HepG2 cells

Vascular Pharmacology

Volumn 40, Issue 6, 2004, Pages 279-284

  Park, Cheol Soo ^a,b   Lee, Young Choon ^c   Kim, Jong Dae ^a,d   Kim, Hyung Min ^e   Kim, Cheorl Ho ^a  

^a Dongguk University   (South Korea)

^b Namwon Eup   (South Korea)

^c Dong A University   (South Korea)

^d Hana Oriental Medical Clinic   (South Korea)

^e Kyung Hee University   (South Korea)

Author keywords

14C oleic acid; ACAT; Acyl coenzyme A cholesterol acyltransferase; Cholesteryl ester; HepG2 cell; LDL; Low density lipoprotein; LPDS; PCWE; Polygonum cuspidatum; Polygonum cuspidatum water extract; Resveratrol; Very low density lipoprotein; VLDL

Indexed keywords

CHOLESTEROL ACYLTRANSFERASE; CHOLESTEROL ESTER; PLANT EXTRACT; POLYGONUM CUSPIDATUM EXTRACT; RESVERATROL; UNCLASSIFIED DRUG;

ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; INCUBATION TIME; LIPOGENESIS; LIVER CELL CULTURE; PRIORITY JOURNAL; TREATMENT FAILURE;

ANIMALS; CELL DIVISION; CELL LINE; CHOLESTEROL ESTERS; DOSE-RESPONSE RELATIONSHIP, DRUG; HEPATOCYTES; HUMANS; MICROSOMES, LIVER; PLANT EXTRACTS; PLANT ROOTS; POLYGONUM CUSPIDATUM; RATS; STEROL O-ACYLTRANSFERASE; STILBENES; WATER;

EID: 1842581940     PISSN: 15371891     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vph.2004.01.003     Document Type: Article

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