Regulation of gene expression by effectors that bind to RNA

Current Opinion in Microbiology

Volumn 7, Issue 2, 2004, Pages 126-131

  Grundy, Frank J ^a   Henkin, Tina M ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

Adenosylcobalamin; AdoCbl; Flavin mononucleotide; FMN; RNA polymerase; RNAP; S adenosylmethionine; SAM; Thiamin pyrophosphate; TPP

Indexed keywords

RNA; TRANSFER RNA;

ANTICODON; BACILLUS SUBTILIS; CODON; EFFECTOR CELL; GENE EXPRESSION REGULATION; GRAM POSITIVE BACTERIUM; NONHUMAN; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN SYNTHESIS REGULATION; REVIEW; RNA BINDING; RNA SPLICING; RNA STRUCTURE; RNA SYNTHESIS; TRANSCRIPTION INITIATION;

BACTERIA; GENE EXPRESSION REGULATION, BACTERIAL; NUCLEIC ACID CONFORMATION; RNA, BACTERIAL;

BACILLUS SUBTILIS; BACTERIA (MICROORGANISMS); POSIBACTERIA;

EID: 1842558364     PISSN: 13695274     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mib.2004.02.013     Document Type: Review

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25. •].
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31. ••].
32. ••].
33. ••], this study demonstrates flavin mononucleotide (FMN) binding to the RFN RNA element. FMN-dependent transcription termination of the rib gene is also demonstrated using T7 RNA polymerase (RNAP) rather than bacterial RNAP.
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36. ••], the authors demonstrate S-adenosylmethionine (SAM)-dependent transcription termination of an S box leader in vitro, and stabilization of the anti-antiterminator element in response to SAM.
37. ••] all leaders tested using bacterial RNAP responded to SAM.
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39. •].
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42. ••].
43. ••] is identified in additional genes and organisms using comparative sequence analysis, and regulation by transcription termination or translation initiation is proposed.
44. ••], describes the L box regulatory motif, and demonstrates lysine-dependent transcription termination of the B. subtilis lysC gene and lysine-dependent structural rearrangements in the leader RNA.