Adipose tissue-derived stromal cells express neuronal phenotypes

Chinese Medical Journal

Volumn 117, Issue 3, 2004, Pages 425-429

  Yang, Li Ye ^a   Liu, Xiang Ming ^a   Sun, Bing ^a   Hui, Guo Zhen ^a   Fei, Jian ^b   Guo, Li He ^b  

^a SOOCHOW UNIVERSITY   (China)

^b INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

Author keywords

Adipose tissue; Neuron; Phenotype; Stromal cells

Indexed keywords

COLLAGENASE; MESSENGER RNA; NESTIN; NEUROFILAMENT PROTEIN; NEURON SPECIFIC ENOLASE;

ADIPOCYTE; ADIPOSE TISSUE; ADIPOSE TISSUE CELL; ANIMAL CELL; ARTICLE; AUTOGRAFT; CARTILAGE CELL; CELL ADHESION; CELL CULTURE; CELL DIFFERENTIATION; CELL STRUCTURE; CELL TRANSPLANTATION; CELL TYPE; CENTRAL NERVOUS SYSTEM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CULTURE MEDIUM; ENZYME DEGRADATION; HYPOTHESIS; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; MESENCHYME; MESENCHYME CELL; MUSCLE CELL; NERVE CELL; NONHUMAN; OSTEOBLAST; PHENOTYPE; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL; STROMA CELL;

ADIPOSE TISSUE; ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; IMMUNOHISTOCHEMISTRY; INTERMEDIATE FILAMENT PROTEINS; NERVE TISSUE PROTEINS; NEUROFILAMENT PROTEINS; NEURONS; PHENOTYPE; PHOSPHOPYRUVATE HYDRATASE; RATS;

EID: 1842555050     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (15)

1. Freed CR, Greene PE, Breeze RE, et al. Transplantation of embryonic dopamine neurons for severe Parkinson's disease. New Engl J Med 2001;344:710-718.
2. Guo Z, Yang J, Liu X, et al. Biological features of mesenchymal stem cells from human bone marrow. Chin Med J 2001;114:950-953.
3. Ferrari G, Gusella-DeAngelis G, Coletta M, et al. Muscle regeneration by bone marrow-derived myogenic precursors. Science 1998;279:1528-1530.
4. Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science 1999;284:143-145.
5. Mezey E, Chandross KJ, Harta G, et al. Turning blood into brain: Cells bearing neuronal antigens generated in vivo from bone marrow. Science 2000;290:1779-1782.
6. Brazelton TR, Rossi FM, Keshet GI, et al. From marrow to brain: Expression of neuronal phenotypes in adultmice. Science 2000;290:1775-1779.
7. Woodbury D, Schwarz EJ, Prockop DJ, et al. Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 2000;61:364-370.
8. Sanchez-Ramos J, Song S, Cardozo-Pelaez F, et al. Adult bone marrow stromal cells differentiate into neural cells in vitro. Exp Neurol 2000;164:247-256.
9. Deng W, Obrocka M, Fischer I, et al. In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP. Bioche Biophy Res Commu 2001;282:148-152.
10. Zuk PA, Zhu M, Mizuno H, et al. Multilineage cells from human adipose tissue: Implications for cell-based therapies. Tissue Eng 2001;7:211-228.
11. Huang JI, Beanes SR, Zhu M, et al. Rat extramedullary adipose tissue as a source of osteochondrogenic progenitor cells. Plast Reconstr Surg 2002;109:1033-1041.
12. Erickson GR, Gimble JM, Franklin DM, et al. Chondrogenic potential of adipose tissue-derived stromal cells in vitro and in vivo. Biochem Biophys Res Commun 2002;290:763-769.
13. Halvorsen YD, Franklin D, Bond AL, et al. Extracellular matrix mineralization and osteoblast gene expression by human adipose tissue-derived stromal cells. Tissue Eng 2001;7:729-741.
14. Azizi SA, Stokes D, Augelli BJ, et al. Engraftment and migration of human bone marrow stromal cells implanted in the brains of albino rats-similarities to astrocytes grafts. Proc Nat Acad Sci USA 1998;95:3908-3913.
15. Kopen GC, Prockop DJ, Pinney DG. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc Nat Acad Sci USA 1999;96:10711-10716.