MHC-peptide binding is assisted by bound water molecules

Journal of Molecular Biology

Volumn 338, Issue 2, 2004, Pages 419-435

  Petrone, Paula M ^a   Garcia, Angel E ^a  

^a LOS ALAMOS NATIONAL LABORATORY   (United States)

Author keywords

Entropy driven binding; ER, endoplasmic reticulum; Gaussian model; HC, heavy chain; Hydration free energy; MSD, mean square displacement; PC, principal components; Principal component analysis; Water coordination

Indexed keywords

EPITOPE; HLA ANTIGEN; ISOLEUCYLLEUCYLLYSYLGLUTAMYLPROLYLVALYLHISTIDYLGLYCYLVALINE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; PEPTIDE; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG; VIRUS ENZYME; WATER;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CRYSTALLOGRAPHY; ENTROPY; HYDRODYNAMICS; HYDROGEN BOND; MAJOR HISTOCOMPATIBILITY COMPLEX; MOLECULAR DYNAMICS; MOLECULE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIMULATION; WATER PERMEABILITY;

EID: 1842534583     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.02.039     Document Type: Article

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