Bilateral Mooren's ulcer in six patients: Diagnosis, surgery and histopathology

International Ophthalmology

Volumn 25, Issue 1, 2004, Pages 1-8

  Kalogeropoulos, Christos D ^a,c   Malamou–Mitsi, Vassiliki D ^b   Aspiotis, Miltiadis B ^a   Psilas, Konstantinos G ^a  

^a UNIVERSITY HOSPITAL OF IOANNINA   (Greece)

^b UNIVERSITY OF IOANNINA   (Greece)

^c NONE   (Greece)

Author keywords

Conjunctival excision; Histopathology; Immunopathology; Mooren's ulcer

Indexed keywords

ANTIBIOTIC AGENT; CYCLOPLEGIC AGENT; DEXAMETHASONE;

ADULT; AGED; ARTICLE; BOWMAN MEMBRANE; CELL INFILTRATION; CHEMOSIS; CLINICAL ARTICLE; CONJUNCTIVAL HYPEREMIA; CORNEA EPITHELIUM; CORNEA RODENT ULCER; CORNEA STROMA; DIFFERENTIAL DIAGNOSIS; FEMALE; HEALING; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; KERATITIS; LYMPHOCYTIC INFILTRATION; MALE; NECROBIOTIC DISORDER; PLASMA CELL; RECURRENT DISEASE; VASCULITIS;

EID: 1842530393     PISSN: 01655701     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:INTE.0000018510.06715.c9     Document Type: Article

References (30)

1. Wood TO, Kaufman HE. Mooren's ulcer. Am J Ophthalmol 1971; 71: 417-422.
2. Robin JB, Dugel R. Immunologic disorders of the cornea and conjunctiva. In: Kaufman H, Barron B, McDonald M, Waltman S, eds. The Cornea. New York, Edinburgh, London, Melbourne: Churchill Livingstone, 1988, pp. 511-561.
3. Robin JB, Schanzlin DJ, Verity SM, Barron BA, Arffa RC, Suarez E, Kaufman HE. Peripheral corneal disorders. Surv Ophthalmol 1986; 31: 1-36.
4. Young RD, Watson PG. Light and electron microscopy of corneal melting syndrome (Mooren's ulcer). Br J Ophthalmol 1982; 66: 341-356.
5. Mondino BJ. Inflammatory diseases of the peripheral cornea. Ophthalmology 1988; 95: 463-472.
6. Duke-Elder S, Leigh AG. Diseases of the outer eye: In: Duke-Elder S, ed. System of Ophthalmology. London: Kimpton, 1965; 8(2), pp. 916-920.
7. Zegans ME, Srinivasan M, McHugh T, Whitcher JP, Margolis TP, Lietman T et al. Mooren ulcer in South India: Serology and clinical risk factors. Am J Ophthalmol 1999; 128(2): 205-210.
8. Brown SI. Mooren's ulcer. Histopathology and proteolytic enzymes of adjacent conjunctiva. Br J Ophthalmol 1975; 59: 670-674.
9. Murray PI, Rahi AH. Pathogenesis of Mooren's ulcer: Some new concepts. Br J Ophthalmol 1984; 68: 182-187.
10. Foster CS, Kenyon KR, Greiner J et al. The immunopathology of Mooren's ulcer. Am J Ophthalmol 1979; 88: 149-159.
11. Tabbara KF, Ostler HB. Mooren's ulcer. In: Trevor-Roper P, ed. Procceding of the 6th Congress of European Ophthalmology. London: Academic Press and Royal Society of Medicine, 1980, pp. 269-273.
12. Gottsch JD, Liu SH, Minkovitz JB, et al. Autoimmunity to a cornea-associated stromal antigen in patients with Mooren's ulcer. Inv Ophthalmol Vis Sci 1995; 36: 1541-1547.
13. Taylor CJ, Smith SI, Morgan CH, Stephenson SF, Key T, Srinivasan M et al. HLA and Mooren's ulceration. Br J Ophthalmol 2000; 84(1): 72-75.
14. Brown SI, Mondino BJ. Therapy of Mooren's ulcer. Am J Ophthalmol 1984; 98: 1-6.
15. Foster CS. Systemic immunosuppressive therapy for progressive bilateral Mooren's ulcer. Ophthalmology 1985; 92: 1436-1439.
16. Donzis PB, Mondino BJ. Management of noninfectious corneal ulcers. Surv Ophthalmol 1987; 32: 94-110.
17. Tiev KP, Borderie VM, Briant M, Ziani M, Morvant C, Baret M, et al. Ulcères de Mooren sévères: Efficacité du traitement par cyclophosphamide en bolus intraveineux mensuels. Rev Med Int 2002; 24(2): 118-122.
18. Wakefield D, Robinson LP. Cyclosporin therapy in Mooren's ulcer. Br J Ophthalmol 1987; 71: 415-417.
19. Stammen J, Althaus C, Sundmacher R. Mooren ulcer. 4 severe bilateral disease courses with systemic cyclosporin A therapy. Klin Monatsbl Augenheilkd 1997; 211(5): 306-311.
20. Brown SI. Mooren's ulcer: Treatment by conjunctival excision. Br J Ophthalmol 1975; 59: 675-682.
21. Martin NF, Stark WJ, Maumenee AE. Treatment of Mooren's and Mooren's-like ulcer by lamellar keratectomy: Report of six eyes and literature review. Ophthalmic Surg 1987; 18: 564-569.
22. Florine CW, Dwyer M, Holland EJ. Wegener's granulomatosis presenting with sclerokeratitis diagnosed by antineutrophil cytoplasmic autoantibodies (ANCA). Surv Ophthalmol 1993; 37: 373-376.
23. Akova YA, Jabbur NS, Foster CS. Ocular presentation of polyarteritis nodosa: Clinical course and management with steroid and cytotoxic therapy. Ophthalmology 1993; 100: 1775-1781.
24. Messmer EM, Foster CS. Vasculitic peripheral ulcerative keratitis. Surv Ophthalmol 1999; 43: 379-396.
25. Sainz de la Maza M, Foster CS. Peripheral ulcerative keratitis and malignancies. Cornea 1994; 13: 364-367.
26. Wilson SE, Lee WM, Murakami C, et al. Mooren-type Hepatitis C virus-associated corneal ulceration. Ophthalmology 1994; 101: 736-745.
27. Pouliquen Y, Dhermy P, Renard G, Goichot-Bonnat L, Foster G, Savoldelli M. Terrien's disease: Clinical and ultrastructural studies, five case reports. Eye 1989; 3: 791-802.
28. Bloomfield SE. Clinical allergy and immunology of the external eye. In: Tasman W, Jaeger EA, eds. Duane's Clinical Ophthalmology, Revised edition, Vol 4, Chap. 2. Philadelphia: Lippincott, 1993, pp. 20-22.
29. Wilson FM II, Grayson M, Ellis FD. Treatment of peripheral cornea ulcers by limbal conjunctivectomy. Br J Ophthalmol 1976; 60: 713-719.
30. Aviel E. Combined cryoapplications and peritomy in Mooren's ulcer. Br J Ophthalmol 1972; 56: 48-51.