Mooren's ulcer. Four severe bilateral courses treated with systemic cyclosporin A;Ulkus Mooren. Vier schwere beidseitige verlaufe unter systemischer ciclosporin-A-therapie

Klinische Monatsblatter fur Augenheilkunde

Volumn 211, Issue 5, 1997, Pages 306-311

  Stammen, Johannes ^a   Althaus, Christoph ^a   Sundmacher, Rainer ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Cyclosporin A; Mooren's ulcer

Indexed keywords

CYCLOSPORIN A;

ADULT; AGED; ARTICLE; AUTOIMMUNITY; CASE REPORT; CORNEA RODENT ULCER; DRUG MEGADOSE; FEMALE; HUMAN; MALE; RELAPSE; RISK ASSESSMENT; TREATMENT OUTCOME; WOUND HEALING;

EID: 0031438059     PISSN: 00232165     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1035140     Document Type: Article

References (30)

1. Adenis JP, Bonnet Blanc JM, Queroy M, Ramaert B, Loubet A. Etude immunopathologique dans un cas d'ulcere de Mooren. Resultats preliminaires. Bull Soc Ophtalmol Fr 1977; 77: 719-721
2. Bell TAG, Hunniseit AG. Cyclosporin A: tissue levels following topical and systemic administration to rabbits. Br J Ophthalmol 1986; 70: 852-855
3. Brown SI. Mooren's ulcer. Treatment by conjunctival excision. Br J Ophthalmol 1975; 59: 675-682
4. Brown SI, Mondino BJ, Rabin BS. Autoimmune phenomenon in Mooren's ulcer. Am J Ophthalmol 1976; 82: 835-840
5. Brown SI, Mondino BJ. Therapy of Mooren's ulcer. Am J Ophthalmol 1984; 98: 1-6
6. Faye M, Lam A, Borzeix A. Traitement de l'ulcere de Mooren par l'association periectomie-corticotherapie. A propos de 6 cas. J Fr Ophtalmol 1991; 14: 629-632
7. Foster CS, Kenyon KR, Greiner J, Greineder DK, Friedland B, Allansmith MR. The immunopathology of Mooren's ulcer. Am J Ophthalmol 1979; 88: 149-159
8. Foster CS. Immunosuppressive therapy for external ocular inflammatory disease. Ophthalmology 1980; 87: 140-149
9. Foster CS. Systemic immunosuppressive therapy for progressive bilateral Mooren's ulcer. Ophthalmology 1985; 92: 1436-1439
10. Gottsch JD, Liu SH, Stark WJ. Mooren's ulcer and evidence of stromal graft rejection after penetrating keratoplasty. Am J Ophthalmol 1992; 113: 412-417
11. Gottsch JD, Liu SH, Minkovitz JB, Goodman DF, Srinivasan M, Start WJ. Autoimmunity to a cornea-associated stromal antigen in patients with Mooren's ulcer. Invest Ophthalmol Vis Sci 1995; 36: 1541-1547
12. Hill JC, Potter P. Treatment of Mooren's ulcer with cyclosporin A: report of three cases. Br J Ophthalmol 1987; 71: 11-15
13. Hofmann H. Ein Beitrag zum Ulcus rodens. Klin Monatsbl Augenheilkd 1971; 159: 460-467
14. Mondino BJ, Brown SI, Rabin BS. Cellular immunity in Mooren's ulcer. Am J Ophthalmol 1978; 85: 788-791
15. Mooren A. Ophthalmiatrische Beobachtungen. Berlin: Hirschwald 1867: 107
16. Mosteller MW, Gebhardt BM, Hamilton AM, Kaufmann HE. Penetration of topical cyclosporin into the rabbit cornea, aqueous humor, and serum. Arch Ophthalmol (Chicago) 1985; 103: 101-102
17. Murray PI, Rahi AHS. Pathogenesis of Mooren's ulcer: some new concepts. Br J Ophthalmol 1984; 68: 182-187
18. Palestine AG, Nussenblatt RB, Chan CC. Cyclosporin penetration into the anterior chamber and cerebrospinal fluid. Am J Ophthalmol 1985; 99: 210-211
19. Pau H. Die Therapie des Ulcus rodens Mooren. Klin Monatsbl Augenheilkd 1978; 173: 62-68
20. Pau H, Schmitt-Graff A. Das Ulcus rodens Mooren als mógliche Autoaggressionskrankheit. Klin Monatsbl Augenheilkd 1983; 183: 192-194
21. Rossa V, Sundmacher R, Schmitt-Graff A, Heering P. Klinischer Krankheitsverlauf, histologische Befunde und therapeutische Probleme bei einem Patienten mit einem beidseitigen Ulcus rodens Mooren. Klm Monatsbl Augenheilkd 1991; 199: 165-169
22. Schaap OL, Feltkamp TEW, Breebaart AC. Circulating antibodies to corneal tissue in a patient suffering from Mooren's ulcer (ulcus rodens corneae). Clin Exp Immunol 1969; 5: 365-370
23. Wakefield D, Robinson LP. Cyclosporin therapy in Mooren's ulcer. Br J Ophthalmol 1987; 71: 415-417
24. Witson PG. Management of Mooren's ulceration. Eye 1997; 11: 349-356
25. Wiebking HJ, Mehlfeld T. Lokale Behandlung von Hornhautulcera und Skleromalazien mit Cyclosporin A. Fortschr Ophthalmol 1986; 83: 345-347
26. Wiederholdt M, Kossendrup D, Schulz W, Hoffmann F. Pharmacokinetic of topical cyclosporin A in the rabbit eye. Invest Ophthalmol Vis Sci 1986; 27: 519-524
27. Wilson SE, Lee WM, Murakami C, Weng J, Moninger GA. Mooren-type hepatitis C virus-associated corneal ulceration Ophthalmology 1994; 101: 736-745
28. Wood TO, Kaufman HE. Mooren's ulcer. Am J Ophthalmol 1971; 71: 417-422
29. Yanoff M, Fine BS. Mooren's ulcer. In: Duane TD, Jaeger EA: Biomedical Foundations of Ophthalmology. Philadelphia. JB Lippincott Company 1988; 9: 19-23
30. Zierhut M, Thiel H-J, Weidle EG, Waetjen R, Pleyer U. Topical treatment of severe corneal ulcers with cyclosporin A. Graefe's Arch Clin Exp Ophthalmol 1989, 227: 30-35