Absorption of taurocholic acid by the ileum of normal and transgenic ΔF508 cystic fibrosis mice

Journal of Pharmacy and Pharmacology

Volumn 56, Issue 4, 2004, Pages 445-452

  Hardcastle, J ^a   Harwood, M D ^a   Taylor, C J ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

BILE ACID; CHLORIDE; EFENAMIC ACID; FUROSEMIDE; SODIUM; TAUROCHOLIC ACID; TRANSMEMBRANE CONDUCTANCE REGULATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRUSH BORDER VESICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYSTIC FIBROSIS; GENE MUTATION; ILEUM; ISOTOPE LABELING; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; SHORT CIRCUIT CURRENT; SMALL INTESTINE ABSORPTION; TRANSGENIC MOUSE;

ANIMALS; BIOLOGICAL TRANSPORT; BLOOD PROTEINS; CALGRANULIN A; CYSTIC FIBROSIS; ELECTRIC CONDUCTIVITY; ILEUM; INTESTINAL ABSORPTION; MALE; MICE; MICROVILLI; MUTATION; TAUROCHOLIC ACID;

EID: 1842524024     PISSN: 00223573     EISSN: None     Source Type: Journal    
DOI: 10.1211/0022357022881     Document Type: Article

References (32)

1. Ameen, N., Alexis, J., Salas, P. (2000) Cellular localization of the cystic fibrosis transmembrane conductance regulator in mouse intestinal tract. Histochem. Cell Biol. 114: 60-75
2. Barnard, J. A., Ghishan, F. K. (1987) Taurocholate transport by human deal brush border membrane vesicles. Gastroenterology 93: 925-933
3. Barrett, K. E., Keely, S. J. (2000) Chloride secretion by the intestinal epithelium: Molecular basis and regulatory aspects. Annu. Rev. Physiol. 62: 532-572
4. Baxter, P. S., Goldhill, J., Hardcastle, J., Hardcastle, P. T., Taylor, C. J. (1990) Enhanced intestinal glucose and alanine transport in cystic fibrosis. Gut 31: 817-820
5. Beesley, A. H., Hardcastle, J., Hardeastle, P. T., Taylor, C. J. (1996) Sodium/glucose cotransporter activity in cystic fibrosis. Arch. Dis. Child. 75: 170
6. Berschneider, H. M., Knowles, M. R., Azizkhan, R. G., Boucher, R. C., Tobey, N. A., Orlando, R. C., Powell, D. W. (1988) Altered intestinal chloride transport in cystic fibrosis. FASEB J. 2: 2625-2629
7. Binder, H. J. (1980) Pathophysiology of bile acid- and fatty acid-induced diarrhea. In: Field, M., Fordtran, J. S., Schultz, S. G. (eds) Secretory diarrhea. Waverley Press, Baltimore, pp 159-178
8. Caspary, W. F. (1973) Increase of active transport of conjugated bile salts in streptozotocin-diabetic rat small intestine. Gut 14: 949-999
9. Colledge, W. H., Abella, B. S., Southern, K. W., Ratcliff, R., Jiang, C., Cheng, S. H., MacVinish, L. J., Anderson, J. R., Cuthbert, A. W., Evans, M. J. (1995) Generation and characterization of a ΔF508 cystic fibrosis mouse model. Nature Genet. 10: 445-452
10. de Rooij, F. W. M., Van Den Berg, J. W. O., Sinaasappel, M., Bosman-Jacobs, E. P., Touw-Blommesteijn, A. C. (1985) Bile acid malabsorption in cystic fibrosis: Membrane vesicles, a tool for revealing the role of the ileal brush border membrane. Acta Pediatr. Scand. 317 (Suppl.): 28-30
11. Dodge, J. A. (1986) Gastrointestinal tract and nutrition in cystic fibrosis: Pathophysiology. J. R. Soc. Med. 79 (Suppl. 12): 27-31
12. Fondacaro, J. D., Heubi, J. E., Kellogg, F. W. (1982) Intestinal bile acid malabsorption in cystic fibrosis: A primary mucosal cell defect. Pediatr. Res. 16: 494-498
13. Greger, R., Schreiber, R., Mall, M., Wissner, A., Hopf, A., Briel, M., Bleich, M., Warth, R., Kunzelmann, K. (2001) Cystic fibrosis and CFTR. Eur. J. Physiol. 443 (Suppl.): 53-57
14. + absorption in cystic fibrosis mice versus normal mice. Am. J. Physiol. 272: G393-G400
15. Hardcastle, J., Hardcastle, P. T., Chapman, J., Taylor, C. J. (2001) Taurocholic acid-induced secretion in normal and cystic fibrosis mouse ileum. J. Pharm. Pharmacol. 53: 711-719
16. Heintze, K., Stewart, C. P., Frizzell, R. A. (1983) Sodium-dependent chloride secretion across rabbit descending colon. Am. J. Physiol. 244: G357-G365
17. Hofmann, A. F. (1998) Bile secretion and the enterohepatic circulation of bile acids. In: Feldman, M., Scharschmidt, B. F., Sleisenger, M. H. (eds) Sleisenger & Fordtran's gastrointestinal and liver disease. 6th edn, W. B. Saunders Company, Philadelphia, pp 937-948
18. Hofmann, A. F., Schteingart, C. D., Lillienau, J. (1991) Biological and medical aspects of active ileal transport of bile-acids. Ann. Med. 23: 169-175
19. +/D-glucose cotransporter activity in mouse small intestine. J. Pharm. Pharmacol. 52: 679-686
20. O'Brien, S., Mulcahy, H., Fenlon, H., O'Broin, A., Casey, M., Burke, A., FitzGerald, M. X., Hegarty, J. E. (1993) Intestinal bile acid malabsorption in cystic fibrosis. Gut 34: 1137-1141
21. O'Loughlin, E. V., Hunt, D. M., Gaskin, K. J., Stiel, D., Bruzuszcak, I. M., Martin, H. C. O., Bambach, C., Smith, R. (1991) Abnormal epithelial transport in cystic fibrosis jejunum. Am. J. Physiol. 260: G758-G763
22. O'Loughlin, E. V., Hunt, D. M., Bostrom, T. E., Hunter, D., Gaskin, K. J., Gyory, A., Cockayne, D. J. H. (1996) X-ray microanalysis of cell elements in normal and cystic fibrosis jejunum: Evidence for chloride secretion in villi. Gastroenterology 110: 411-418
23. Riordan, J. R. (1993) The cystic fibrosis transmembrane conductance regulator. Annu. Rev. Physiol. 55: 609-630
24. - permeabilities in primary cultures of human and rabbit colonocytes. Am. J. Physiol. 266: G846-G855
25. St-Pierre, M. V., Kullak-Ublick, G. A., Hagenbuch, B., Meier, P. J. (2001) Transport of bile acids in hepatic and non-hepatic tissues. J. Exp. Biol. 204: 1673-1686
26. Stelzner, M., Hoagland, V., Somasundaram, S. (2000) Distribution of bile acid absorption and bile acid transporter gene message in the hamster ileum. Eur. J. Physiol. 440: 157-162
27. Stelzner, M., Somasundaram, S., Lee, S. P., Kuver, R. (2001) Ileal mucosal bile acid absorption is increased in Cftr knockout mice. BMC Gastroenterol. 1: 10-16
28. Taylor, C. J., Baxter, P. S., Hardcastle, J., Hardcastle, P. T. (1987) Absence of secretory response in jejunal biopsy samples from children with cystic fibrosis. Lancet ii: 107-108
29. Taylor, C. J., Baxter, P. S., Hardcastle, J., Hardcastle, P. T. (1988) Failure to induce secretion in jejunal biopsy samples from children with cystic fibrosis. Gut 29: 957-962
30. Thompson, G. N., Davidson, G. P. (1988) In vivo bile acid uptake from terminal ileum in cystic fibrosis. Pediatr. Res. 23: 323-328
31. Ung, K.-A., Olofsson, G., Fae, A., Kilander, A., Ohlsson, C., Jonsson, O. (2002) In vitro determination of active bile acid absorption in small biopsy specimens obtained endoscopically or surgically from the human intestine. Eur. J. Clin. Invest. 32: 115-121
32. Veeze, H. J. (1992) Cystic fibrosis: Genetics and intestinal secretion. Neth. J. Med. 41: 115-118