Both Viral and Host Factors Contribute to Neurovirulence of Bovine Herpesviruses 1 and 5 in Interferon Receptor-Deficient Mice

Journal of Virology

Volumn 78, Issue 7, 2004, Pages 3644-3653

  Abril, Carlos ^a   Engels, Monika ^a   Liman, Anne ^a,b   Hilbe, Monika ^a   Albini, Sarah ^a   Franchini, Marco ^a,c   Suter, Mark ^a   Ackermann, Mathias ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b Universität Zürich ^*  (United States)

^c UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; GAMMA INTERFERON; INTERFERON RECEPTOR; RAG2 PROTEIN; VIRUS DNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BOVINE HERPES VIRUS; BOVINE HERPES VIRUS 5; CONTROLLED STUDY; HERPES SIMPLEX VIRUS 1; HISTOPATHOLOGY; IMMUNE SYSTEM; LYMPHOCYTOPOIESIS; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; TH1 CELL; VIREMIA; VIRUS CELL INTERACTION; VIRUS INFECTION; VIRUS REPLICATION; VIRUS VIRULENCE; ANIMAL; BRAIN; CATTLE; DISEASE MODEL; GENETICS; HERPES VIRUS INFECTION; IMMUNOLOGY; INFECTIOUS BOVINE RHINOTRACHEITIS VIRUS; NERVE CELL; NERVE FIBER TRANSPORT; PATHOGENICITY; PHYSIOLOGY; VARICELLA ZOSTER VIRUS; VIROLOGY; VIRULENCE;

ANIMALS; AXONAL TRANSPORT; BRAIN; CATTLE; DISEASE MODELS, ANIMAL; DNA, VIRAL; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 1, BOVINE; HERPESVIRUS 5, BOVINE; INTERFERON TYPE II; MICE; NEURONS; RECEPTORS, INTERFERON; TH1 CELLS; VIREMIA; VIRULENCE; VIRUS REPLICATION;

EID: 1842457762     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.7.3644-3653.2004     Document Type: Article

References (45)

1. Abu-Shakra, M., and Y. Shoenfeld. 1991. Chronic infections and autoimmunity. Immunol. Ser. 55:285-313.
2. Aguilar-Delfin, I., P. J. Wettstein, and D. H. Persing. 2003. Resistance to acute babesiosis is associated with interleukin-12- and gamma interferon-mediated responses and requires macrophages and natural killer cells. Infect. Immun. 71:2002-2008.
3. Ashkar, A. A., G. P. Black, Q. Wei, H. He, L. Liang, J. R. Head, and B. A. Croy. 2003. Assessment of requirements for IL-15 and IFN regulatory factors in uterine NK cell differentiation and function during pregnancy. J. Immunol. 171:2937-2944.
4. Bagust, T. J., and L. Clark. 1972. Pathogenesis of meningo-encephalitis produced in calves by infectious bovine rhinotracheitis herpesvirus. J. Comp. Pathol. 82:375-383.
5. Barenfus, M., C. A. Delliquadri, R. W. McIntyre, and R. J. Schroeder. 1963. Isolation of infectious bovine rhinotracheitis virus from calves with meningo-encephalitis. J. Am. Vet. Med. Assoc. 143:725-728.
6. Biron, C. A. 1999. Initial and innate responses to viral infections-pattern setting in immunity or disease. Curr. Opin. Microbiol. 2:374-381.
7. Biron, C. A. 1998. Role of early cytokines, including alpha and beta interferons (IFN-alpha/beta), in innate and adaptive immune responses to viral infections. Semin. Immunol. 10:383-390.
8. Boehm, U., T. Klamp, M. Groot, and J. C. Howard. 1997. Cellular responses to interferon-gamma. Annu. Rev. Immunol. 15:749-795.
9. Bulach, D. M., and M. J. Studdert. 1990. Comparative genome mapping of bovine encephalitis herpesvirus, bovine herpesvirus 1, and buffalo herpesvirus. Arch. Virol. 113:17-34.
10. Campadelli-Fiume, G., F. Cocchi, L. Menotti, and M. Lopez. 2000. The novel receptors that mediate the entry of herpes simplex viruses and animal alphaherpesviruses into cells. Rev. Med. Virol. 10:305-319.
11. Chowdhury, M., and S. I. Chowdhury. 1997. Neuropathology of bovine herpesvirus type 5 (BHV-5) meningo-encephalitis in a rabbit seizure model. Mol. Hum. Reprod. 3:109-114.
12. Chowdhury, S. I., B. J. Lee, M. Onderci, M. L. Weiss, and D. Mosier. 2000. Neurovirulence of glycoprotein C (gC)-deleted bovine herpesvirus type-5 (BHV-5) and BHV-5 expressing BHV-1 gC in a rabbit seizure model. J. Neurovirol. 6:284-295.
13. Chowdhury, S. I., B. J. Lee, A. Ozkul, and M. L. Weiss. 2000. Bovine herpesvirus 5 glycoprotein E is important for neuroinvasiveness and neurovirulence in the olfactory pathway of the rabbit. J. Virol. 74:2094-2106.
14. Chowdhury, S. I., M. Onderci, P. S. Bhattacharjee, A. Al-Mubarak, M. L. Weiss, and Y. Zhou. 2002. Bovine herpesvirus 5 (BHV-5) Us9 is essential for BHV-5 neuropathogenesis. J. Virol. 76:3839-3851.
15. Cocchi, F., L. Menotti, P. Mirandola, M. Lopez, and G. Campadelli-Fiume. 1998. The ectodomain of a novel member of the immunoglobulin subfamily related to the poliovirus receptor has the attributes of a bona fide receptor for herpes simplex virus types 1 and 2 in human cells. J. Virol. 72:9992-10002.
16. de Waal Malefyt, R. 1997. The role of type I interferons in the differentiation and function of Th1 and Th2 cells. Semin. Oncol. 24:S9-94-S9-98.
17. Engels, M., and M. Ackermann. 1996. Pathogenesis of ruminant herpesvirus infections. Vet. Microbiol. 53:3-15.
18. Fernandez, N. C., A. Lozier, C. Flament, P. Ricciardi-Castagnoli, D. Bellet, M. Suter, M. Perricaudet, T. Tursz, E. Maraskovsky, and L. Zitvogel. 1999. Dendritic cells directly trigger NK cell functions: cross-talk relevant in innate anti-tumor immune responses in vivo. Nat. Med. 5:405-411.
19. Fraefel, C., T. Heister, and M. Ackermann. 2003. Herpes simplex type 1/adeno-associated virus hybrid vectors. Gene Ther. Regulat. 2:7-28.
20. French, E. L. 1962. A specific virus encephalitis in calves: isolation and characterization of the causal agent. Aust. Vet. J. 38:216-221.
21. Friedli, K., and A. E. Metzler. 1987. Reactivity of monoclonal antibodies to proteins of a neurotropic bovine herpesvirus 1 strain and to proteins of representative BHV-1 strains. Arch. Virol. 94:109-122.
22. Geiger, K. D., T. C. Nash, S. Sawyer, T. Krahl, G. Patstone, J. C. Reed, S. Krajewski, D. Dalton, M. J. Buchmeier, and N. Sarvetnick. 1997. Interferon-gamma protects against herpes simplex virus type 1-mediated neuronal death. Virology 238:189-197.
23. Goldsby, R. A., T. J. Kindt, and B. A. Osborne (ed.). 2002. Kuby immunology, 4th ed. W. H. Freeman and Company, New York, N.Y.
24. Grob, P., V. E. Schijns, M. F. van den Broek, S. P. Cox, M. Ackermann, and M. Suter. 1999. Role of the individual interferon systems and specific immunity in mice in controlling systemic dissemination of attenuated pseudorabies virus infection. J. Virol. 73:4748-4754.
25. Huang, S., W. Hendriks, A. Althage, S. Hemmi, H. Bluethmann, R. Kamijo, J. Vilcek, R. M. Zinkernagel, and M. Aguet. 1993. Immune response in mice that lack the interferon-gamma receptor. Science 259:1742-1745.
26. Hussy, D., N. Stauber, C. M. Leutenegger, S. Rieder, and M. Ackermann. 2001. Quantitative fluorogenic PCR assay for measuring ovine herpesvirus 2 replication in sheep. Clin. Diagn. Lab. Immunol. 8:123-128.
27. Johnson, R. T. 2003. Emerging viral infections of the nervous system. J. Neurovirol. 9:140-147.
28. Johnson, R. T. 1995. Neurovirology: evolution of a new discipline. J. Neurovirol. 1:2-4.
29. Landolfo, S., G. Gribaudo, A. Angeretti, and M. Gariglio. 1995. Mechanisms of viral inhibition by interferons. Pharmacol Ther. 65:415-442.
30. Lee, B. J., M. L. Weiss, D. Mosier, and S. I. Chowdhury. 1999. Spread of bovine herpesvirus type 5 (BHV-5) in the rabbit brain after intranasal inoculation. J. Neurovirol. 5:474-484.
31. Liman, A., M. Engels, G. Meyer, M. Ackermann. 2000. Glycoprotein C of bovine herpesvirus 5 (BHV-5) confers a distinct heparin-binding phenotype to BHV-1. Arch. Virol. 145:2047-2059.
32. Metzler, A. E., A. A. Schudel, and M. Engels. 1986. Bovine herpesvirus 1: molecular and antigenic characteristics of variant viruses isolated from calves with neurological disease. Arch. Virol. 87:205-217.
33. Meyer, G., M. Lemaire, J. Lyaku, P. P. Pastoret, and E. Thiry. 1996. Establishment of a rabbit model for bovine herpesvirus type 5 neurological acute infection. Vet. Microbiol. 51:27-40.
34. Meyer, G., M. Lemaire, C. Ros, K. Belak, A. Gabriel, D. Cassart, F. Coignoul, S. Belak, and E. Thiry. 2001. Comparative pathogenesis of acute and latent infections of calves with bovine herpesvirus types 1 and 5. Arch. Virol. 146:633-652.
35. Muller, U., U. Steinhoff, L. F. Reis, S. Hemmi, J. Pavlovic, R. M. Zinkernagel, and M. Aguet. 1994. Functional role of type I and type II interferons in antiviral defense. Science 264:1918-1921.
36. Probst, U., R. Wyler, U. Kihm, M. Ackermann, L. Bruckner, H. K. Muller, and F. Ehrensperger. 1985. Zur IBR-Virus-Ausscheidung experimentell infizierter Kühe insbesondere in der Milch. Schweizer Arch. Tierheilkunde. 127:723-733.
37. Roels, S., G. Charlier, C. Letellier, G. Meyer, F. Schynts, P. Kerkhofs, E. Thiry, and E. Vanopdenbosch. 2000. Natural case of bovine herpesvirus 1 meningoencephalitis in an adult cow. Vet. Rec. 146:586-588.
38. Rosskopf, M., E. Staub, and M. Ackermann. 1994. Vergleich zweier ELISA Systeme zum Nachweis von Antikorpern gegen IBR/IPV sowie gegen EBL. Schweizer Arch. Tierheilkunde. 136:58-67.
39. Schudel, A. A., B. J. Carrillo, R. Wyler, and A. E. Metzler. 1986. Infections of calves with antigenic variants of bovine herpesvirus 1 (BHV-1) and neurological disease. Zbl. Vet. Reihe B 33:303-310.
40. Six, A., M. Banks, M. Engels, C. R. Bascunana, and M. Ackermann. 2001. Latency and reactivation of bovine herpesvirus 1 (BHV-1) in goats and of caprine herpesvirus 1 (CapHV-1) in calves. Arch. Virol. 146:1325-1335.
41. Vanderlugt, C. L., K. L. Neville, K. M. Nikcevich, T. N. Eagar, J. A. Bluestone, and S. D. Miller. 2000. Pathologic role and temporal appearance of newly emerging autoepitopes in relapsing experimental autoimmune encephalomyelitis. J. Immunol. 164:670-678.
42. Vogtlin, A., C. Fraefel, S. Albini, C. M. Leutenegger, E. Schraner, B. Spiess, H. Lutz, and M. Ackermann. 2002. Quantification of feline herpesvirus 1 DNA in ocular fluid samples of clinically diseased cats by real-time TaqMan PCR. J. Clin. Microbiol. 40:519-523.
43. Vogtlin, A., C. Fraefel, R. Kocherhans, C. M. Leutenegger, K. Frei, A. Fontana, and M. Ackermann. 2002. HSV-1-based amplicon particles are able to transduce cells of feline origin with genes encoding biologically functional feline IL-10 or IL-6. Vet. Microbiol. 86:103-113.
44. Wyler, R., M. Engels, and M. Schwyzer. 1989. Infectious bovine rhinotracheitis/vulvovaginitis (BHV1). Kluwer Academic Publishers, Boston, Mass.
45. Zhang, G., R. D. Nichols, M. Taniguchi, T. Nakayama, and M. J. Parmely. 2003. Gamma interferon production by hepatic NK T cells during Escherichia coli infection is resistant to the inhibitory effects of oxidative stress. Infect. Immun. 71:2468-2477.