Determination of hydroxyl radicals using salicylate as a trapping agent by gas chromatography-mass spectrometry

Clinical Biochemistry

Volumn 30, Issue 1, 1997, Pages 41-46

  Luo, Xiaoping ^a   Lehotay, Denis C ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

catechol; dihydroxybenzoic acid; gas chromatography mass spectrometry; hydroxyl radical; salicylic acid

Indexed keywords

ACETYLSALICYLIC ACID; HYDROXYL RADICAL;

ARTICLE; BLOOD CHEMISTRY; CHEMICAL ANALYSIS; DIAGNOSTIC ACCURACY; GAS CHROMATOGRAPHY; HUMAN; HYDROXYLATION; MASS SPECTROMETRY; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL;

FREE RADICAL SCAVENGERS; FREE RADICALS; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; HYDROXYL RADICAL; REPRODUCIBILITY OF RESULTS; SALICYLIC ACID; SALICYLIC ACIDS; SENSITIVITY AND SPECIFICITY;

EID: 0031027507     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9120(96)00137-3     Document Type: Article

References (30)

1. Halliwell B, Gutteridge JMC. Free radicals in biology and medicine. 2nd ed. Oxford: Clarendon Press, 1989.
2. Gutteridge JMC. Free radicals in disease processes: a complication of cause and consequence. Free Rad Res Commun 1993; 19: 141-58.
3. Toyokuni S, Okamoto K, Yodoi J, Hiai H. Persistent oxidative stress in cancer. FEBS Lett 1995; 358: 1-3.
4. Cheeseman KH, Slater TF. Free radicals in medicine. Br Med Bull 1993; 49: 479-724.
5. Obata T, Hosokawa H, Yamanaka Y. Effect of ferrous iron on the generation of hydroxyl free radicals by liver microdialysis perfusion of salicylate. Comp Biochem Physiol-C 1993; 106: 629-34.
6. Halliwell B, Gutteridge JMC. Oxygen toxicity, oxygen radicals, transition metals and disease. Biochem J 1984; 219: 1-14.
7. Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl production by peroxynitrite: implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 1990; 87: 1620-24.
8. Kaur H, Halliwell B. Detection of hydroxyl radicals by aromatic hydroxylation. Methods Enzym 1994; 233: 67-82.
9. 2-reactive species in oxygen toxicity in biology. J Biol Chem 1990; 265: 13589-94.
10. Halliwell B. Superoxide-dependent formation of hydroxyl radicals in the presence of iron chelates: is it a mechanism for hydroxyl radical production in biochemical system? FEBS Lett 1978; 92: 321-6.
11. . radicals in ischemic/reperfused hearts. A relationship between the genesis of free radicals and reperfusion arrhythmias. Biochem Pharmacol 1993; 45: 961-9.
12. Singh S, Hider RC. Colorimetric detection of the hydroxyl radical: comparison of the hydroxyl-radical-generating ability of various iron complexes. Anal Biochem 1988; 171: 47-54.
13. Fujimoto S, Kawakami N, Ohara A. Hydroxylation of phenylalanine and salicylate by stimulated polymorphonuclear leukocytes and the accelerating effect of glutathione on their hydroxylation. Biol Pharm Bull 1994; 17: 767-72.
14. Coudray C, Talla M, Martin S, Fatôme M, Favier A. High-performance liquid chromatography-electrochemical determination of salicylate hydroxylation products as in vivo marker of oxidative stress. Anal Biochem 1995; 227: 101-11.
15. Rumble RH, Roberts MS. Determination of aspirin and its major metabolites in plasma by high-performance liquid chromatography without solvent extraction. J Chromatog 1981; 225: 252-60.
16. Grootveld M, Halliwell B. 2,3-Dihydroxybenzoic acid is a product of human aspirin metabolism. Biochem Pharmacol 1988; 37: 271-80.
17. Maskos Z, Rush JD, Koppenol WH. The hydroxylation of the salicylate anion by a Fenton reaction and T-radiolysis: a consideration of the respective mechanisms. Free Rad Biol Med 1990; 8: 153-62.
18. Halliwell B, Kaur H, Ingelman-Sundberg M. Hydroxylation of salicylate as an assay for hydroxyl radicals: a cautionary note. Free Rad Biol Med 1991; 10: 439-41.
19. Ingelman-Sundberg M, Kaur J, Terelius Y, Persson JO, Halliwell B. Hydroxylation of salicylate by microsomal fractions and cytochrome P-450. Lack of production of 2,3-dihydroxybenzoate unless hydroxyl radical formation is permitted. Biochem J 1991; 276: 753-7.
20. Winston GW, Cederbaum AI. Oxidative decarboxylation of benzoate to carbon dioxide by rat liver microsomes: a probe for oxygen radical production during microsomal electron transfer. Biochemistry 1982; 21: 4265-70.
21. Hiller KO, Hodd PL, Wilson RC. Antiflammatory drugs: protection of a bacterial virus as an in vitro biological measure of free radical activity. Chem Biol Interact 1983; 47: 293-305.
22. O'Connell MJ, Webster NR. Hyperoxia and salicylate metabolism in rats. J Pharm Pharmacol 1990; 42: 205-6.
23. Floyd RA, Henderson R, Watson JJ, Wong PK. Use of salicylate with high pressure liquid chromatography and electrochemical detection (LCED) as a sensitive measure of hydroxyl free radicals in adriamysin treated rats. Free Rad Biol Med 1986; 2: 13-8.
24. Grootveld M, Halliwell B. Aromatic hydroxylation as a potential measure of hydroxyl radical formation in vivo. Identification of hydroxylated derivatives of salicylate in human body fluids. Biochem J 1986; 237: 488-504.
25. Tubaro M, Cavallo G, Pensa V, Chessa MA, Natale E, Ricci R, et al. Demonstration of the formation of hydroxyl radicals in acute myocardial infarction in man using salicylate as probe. Cardiology 1992; 80: 246-51.
26. Globus MY, Busto R, Lin B, Schnippering H, Ginsberg MD. Detection of free radical activity during transient global ischemia and recirculate: effects of intraischemic brain temperature modulation. J Neurochem 1995; 65: 1250-6.
27. Ghiselli A, Laurenti O, De Mattia G, Maiani G, Ferro-Luzzi A. Salicylate hydroxylation as an early marker of in vivo oxidative stress in diabetic patients. Free Rad Biol Med 1992; 13: 621-6.
28. Schapira RM, Ghio AJ, Effros RM, Morrisey J, Almagro UA, Dawson CA, et al. Hydroxyl radical production and lung injury in the rat following silica or titanium dioxide instillation in vivo. Am J Res Cell Mol Biol 1995; 12: 220-6.
29. Kadkhodaee M, Endre ZH, Towner RA, Cross M. Hydroxyl radical generation following ischaemia-reperfusion in cell-free perfused rat kidney. Biochim Biophys Acta 1995; 1243: 169-74.
30. Buerke M, Pittroff W, Meyer J, Darius H. Aspirin therapy: optimized platelet inhibition with different loading and maintenance doses. Am Heart J 1995; 130: 465-72.