메뉴 건너뛰기




Volumn 99, Issue 1, 1997, Pages 25-30

Inositol hexaphosphate (IP6) reduces risk for cancer and cardiovascular diseases

Author keywords

Cancer; Cardiovascular diseases; Mositol hexaphosphate

Indexed keywords

ANTINEOPLASTIC AGENT; ANTITHROMBOCYTIC AGENT; INOSITOL PHOSPHATE; PHYTIC ACID;

EID: 1842334452     PISSN: 00315362     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (8)

References (61)
  • 1
    • 0028909094 scopus 로고
    • Evaluation of chemopreventive agents in different mechanistic classes using a rat tracheal epithelial cell culture transformation assay
    • ARNOLD J T, WILKINSON B P, SHARMA S, STEELE V E 1995 Evaluation of chemopreventive agents in different mechanistic classes using a rat tracheal epithelial cell culture transformation assay. Cancer Res 55: 537-543
    • (1995) Cancer Res , vol.55 , pp. 537-543
    • Arnold, J.T.1    Wilkinson, B.P.2    Sharma, S.3    Steele, V.E.4
  • 2
    • 0027493434 scopus 로고
    • Comparative cytotoxicities of selected minor dietary non-nutrients with chemopreventive properties
    • BABICH H, BORENFREUND E, STERN A 1993 Comparative cytotoxicities of selected minor dietary non-nutrients with chemopreventive properties. Cancer Lett 73: 127-133
    • (1993) Cancer Lett , vol.73 , pp. 127-133
    • Babich, H.1    Borenfreund, E.2    Stern, A.3
  • 3
    • 0029869197 scopus 로고    scopus 로고
    • Dietary fiber reduces blood pressure, serum total cholesterol and platelet aggregation in rats
    • BAGGER M, ANDERSEN O, NIELSEN J B, RYTTIG K R 1996 Dietary fiber reduces blood pressure, serum total cholesterol and platelet aggregation in rats. British J Nutr 75: 483-493
    • (1996) British J Nutr , vol.75 , pp. 483-493
    • Bagger, M.1    Andersen, O.2    Nielsen, J.B.3    Ryttig, K.R.4
  • 4
    • 0024425063 scopus 로고
    • Inositol-phosphate-induced enhancement of natural killer cell activity correlates with tumor suppression
    • BATEN A, ULLAH A, TOMAŽIĆ V J, SHAMSUDDIN A M 1989 Inositol-phosphate-induced enhancement of natural killer cell activity correlates with tumor suppression. Carcinogenesis 10: 1595-1598
    • (1989) Carcinogenesis , vol.10 , pp. 1595-1598
    • Baten, A.1    Ullah, A.2    Tomažić, V.J.3    Shamsuddin, A.M.4
  • 5
    • 0027397544 scopus 로고
    • Inositol trisphosphate and calcium signalling
    • BERRIDGE M J 1993 Inositol trisphosphate and calcium signalling. Nature (London) 361: 315-325
    • (1993) Nature (London) , vol.361 , pp. 315-325
    • Berridge, M.J.1
  • 7
    • 0029090825 scopus 로고
    • Cell signalling by integrins and immunoglobulin receptors in primed neutrophils
    • EDWARDS S W 1995 Cell signalling by integrins and immunoglobulin receptors in primed neutrophils. Trends Biochem Sci 20: 362-367
    • (1995) Trends Biochem Sci , vol.20 , pp. 362-367
    • Edwards, S.W.1
  • 9
    • 0027452033 scopus 로고
    • Studies of chemopreventive effects of myo-inositol on benz(a)pyrene-induced neoplasia of the lung and forestomach of female A/J mice
    • ESTENSEN R D, WATTENBERG L W 1993 Studies of chemopreventive effects of myo-inositol on benz(a)pyrene-induced neoplasia of the lung and forestomach of female A/J mice. Carcinogenesis 14: 1975-1977
    • (1993) Carcinogenesis , vol.14 , pp. 1975-1977
    • Estensen, R.D.1    Wattenberg, L.W.2
  • 10
    • 0029894287 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of the Fc receptor gamma-chain in collagen-stimulated platelets
    • GIBBINS J, ASSELIN J, FERNDALE R, BARNES M, LAW C L, WATSON S P 1996 Tyrosine phosphorylation of the Fc receptor gamma-chain in collagen-stimulated platelets. J Biol Chem 271: 18095-18099
    • (1996) J Biol Chem , vol.271 , pp. 18095-18099
    • Gibbins, J.1    Asselin, J.2    Ferndale, R.3    Barnes, M.4    Law, C.L.5    Watson, S.P.6
  • 11
    • 0345517377 scopus 로고
    • Fiber and breast cancer: From epidemiological studies to intervention studies
    • GERBER M 1994 Fiber and breast cancer: from epidemiological studies to intervention studies. Dietary Fiber Bibliog and Reviews 2: 5-10
    • (1994) Dietary Fiber Bibliog and Reviews , vol.2 , pp. 5-10
    • Gerber, M.1
  • 12
    • 0023664866 scopus 로고
    • Phytic acid: A natural antioxidant
    • GRAF E, EMPSON K L, EATON, J W 1987 Phytic acid: A natural antioxidant. J Biol Chem 262: 11647-11650
    • (1987) J Biol Chem , vol.262 , pp. 11647-11650
    • Graf, E.1    Empson, K.L.2    Eaton, J.W.3
  • 16
    • 0026072276 scopus 로고
    • Modifying effects of the neturally occuring antioxidants goryzanol, phytic acid, tannic acid and n-tritriacontane-16,18-dione in rat a wide-spectrum organ carcinogenesis model
    • HIROSE M, OZAKI K, TAKABA K, FUKUSHIMA S, SHIRAI T, ITO N 1991 Modifying effects of the neturally occuring antioxidants goryzanol, phytic acid, tannic acid and n-tritriacontane-16,18-dione in rat a wide-spectrum organ carcinogenesis model. Carcinogenesis 12: 1917-1921
    • (1991) Carcinogenesis , vol.12 , pp. 1917-1921
    • Hirose, M.1    Ozaki, K.2    Takaba, K.3    Fukushima, S.4    Shirai, T.5    Ito, N.6
  • 17
    • 0027933570 scopus 로고
    • Inhibition of mammary gland carcinogenesis by green tea catechin and other naturally occuring antioxidants in female Sprague-Dawley rats pretreated with 7,12-dimethylbenzŠaĆ anthracene
    • HIROSE M, HOSHIYA T, AKAGI K, FUTAKUSHI M, ITO N 1994 Inhibition of mammary gland carcinogenesis by green tea catechin and other naturally occuring antioxidants in female Sprague-Dawley rats pretreated with 7,12-dimethylbenzŠaĆ anthracene. Cancer Lett 83: 149-156
    • (1994) Cancer Lett , vol.83 , pp. 149-156
    • Hirose, M.1    Hoshiya, T.2    Akagi, K.3    Futakushi, M.4    Ito, N.5
  • 18
    • 0028288293 scopus 로고
    • Receptors for ADP on human blood platelets
    • HOURANI S M O, HALL D A 1994 Receptors for ADP on human blood platelets. Trends Pharmacol Sci 15: 103-108
    • (1994) Trends Pharmacol Sci , vol.15 , pp. 103-108
    • Hourani, S.M.O.1    Hall, D.A.2
  • 19
    • 0023752845 scopus 로고
    • Effect of dietary phytic acid (phytate) on the incidence and growth rate of tumors promoted in Fisher rats by magnesium supplement
    • JARIWALLA RJ, SABIN R, LAWSON S, BLOCH D A, PRENDER M, ANDREWS V, HERMAN Z S 1988 Effect of dietary phytic acid (phytate) on the incidence and growth rate of tumors promoted in Fisher rats by magnesium supplement. Nutr Res 8: 813-827
    • (1988) Nutr Res , vol.8 , pp. 813-827
    • Jariwalla, R.J.1    Sabin, R.2    Lawson, S.3    Bloch, D.A.4    Prender, M.5    Andrews, V.6    Herman, Z.S.7
  • 20
    • 0025224193 scopus 로고
    • Lowering of serum cholesterol and triglycerides and modulations by dietary phytate
    • JARIWALLA R J, SABIN R, LAWSON S, HERMAN Z S 1990 Lowering of serum cholesterol and triglycerides and modulations by dietary phytate. J Appl Nutr 42: 18-28
    • (1990) J Appl Nutr , vol.42 , pp. 18-28
    • Jariwalla, R.J.1    Sabin, R.2    Lawson, S.3    Herman, Z.S.4
  • 21
    • 0029621132 scopus 로고
    • Phytic acid, an iron chelator, attenuates pulmonary inflammation and fibrosis in rats after intratracheal instillation of asbestos
    • KAMP DW, ISRABIAN V A, YELDANDI A V, PANOS R J, GRACEFFA P, WEITZMAN S A 1995 Phytic acid, an iron chelator, attenuates pulmonary inflammation and fibrosis in rats after intratracheal instillation of asbestos. Toxicol Pathol 23: 689-695
    • (1995) Toxicol Pathol , vol.23 , pp. 689-695
    • Kamp, D.W.1    Israbian, V.A.2    Yeldandi, A.V.3    Panos, R.J.4    Graceffa, P.5    Weitzman, S.A.6
  • 22
    • 0029315269 scopus 로고
    • Effect of dietary sodium phytate on the hepatic and serum levels of lipids and on hepatic activities of NADPH-generating enzymes in rats fed on sucrose
    • KATAYAMA T 1995 Effect of dietary sodium phytate on the hepatic and serum levels of lipids and on hepatic activities of NADPH-generating enzymes in rats fed on sucrose. Biosci Biotech Biochem 59: 1159-1160
    • (1995) Biosci Biotech Biochem , vol.59 , pp. 1159-1160
    • Katayama, T.1
  • 25
    • 0002524999 scopus 로고
    • Phytates
    • National Academic Science, Washington, DC
    • OBERLEAS D 1973 Phytates. In: Toxicants Occuring Naturally in Foods. National Academic Science, Washington, DC, p 363-371
    • (1973) Toxicants Occuring Naturally in Foods , pp. 363-371
    • Oberleas, D.1
  • 26
    • 0021752556 scopus 로고
    • Rice bran treatment for patients with hypercalciuric stones: Experimental and clinical studies
    • OHKAWA T, EBISUNO S, KITAGAWA M, MARIMOTO S, MIYAZAKI Y, YASUKAWA S 1984 Rice bran treatment for patients with hypercalciuric stones: experimental and clinical studies. J Urol 132: 1140-1145
    • (1984) J Urol , vol.132 , pp. 1140-1145
    • Ohkawa, T.1    Ebisuno, S.2    Kitagawa, M.3    Marimoto, S.4    Miyazaki, Y.5    Yasukawa, S.6
  • 27
    • 0025634188 scopus 로고
    • Studies on the blood anticoagulant activity of phytic acid, Na salt
    • PAL M K, MANDAL N 1990 Studies on the blood anticoagulant activity of phytic acid, Na salt. Indian J Biochem 27: 348-349
    • (1990) Indian J Biochem , vol.27 , pp. 348-349
    • Pal, M.K.1    Mandal, N.2
  • 28
    • 0028897866 scopus 로고
    • Induction of protein tyrosine phosphorylation in human natural killer cells by triggering via a4b1 or a5b1 integrins
    • RABINOWICH H, LIN W-C, MANCIULEA M, HERBERMAN RB, WHITESlDE T 1995 Induction of protein tyrosine phosphorylation in human natural killer cells by triggering via a4b1 or a5b1 integrins. Blood 85: 1858-1864
    • (1995) Blood , vol.85 , pp. 1858-1864
    • Rabinowich, H.1    Lin, W.-C.2    Manciulea, M.3    Herberman, R.B.4    Whiteslde, T.5
  • 30
    • 0030042790 scopus 로고    scopus 로고
    • Vegetable, fruit, and cereal fiber intake intake and risk of coronary heart disease among men
    • RIMM E B, ASCHERIO A, GIOVANNUCCI E, SPIEGELMAN D, STAMPFER M J, WILLETT W C 1996 Vegetable, fruit, and cereal fiber intake intake and risk of coronary heart disease among men. JAMA 275: 447-45.
    • (1996) JAMA , vol.275 , pp. 447-545
    • Rimm, E.B.1    Ascherio, A.2    Giovannucci, E.3    Spiegelman, D.4    Stampfer, M.J.5    Willett, W.C.6
  • 31
    • 0028918456 scopus 로고
    • Regulation of phosphatidylinositide 3-kanase, a potential signaling enzyme in platelets
    • RITTENHOUSE S E 1995 Regulation of phosphatidylinositide 3-kanase, a potential signaling enzyme in platelets. Sem Hematol 32: 120-125
    • (1995) Sem Hematol , vol.32 , pp. 120-125
    • Rittenhouse, S.E.1
  • 32
    • 0023911870 scopus 로고
    • Second messengers involved in superoxide production by neutrophils
    • SADDLER K L, BADWEY J A 1988 Second messengers involved in superoxide production by neutrophils. Hematol/Oncol Clinics North Amer 2: 185-200
    • (1988) Hematol/Oncol Clinics North Amer , vol.2 , pp. 185-200
    • Saddler, K.L.1    Badwey, J.A.2
  • 33
    • 0027442548 scopus 로고
    • Growth inhibition and differentiation of HT-29 cells in vitro by inositol hexaphosphate (phytic acid)
    • SAKAMOTO K, VENKATRAMAN G, SHAMSUDDIN A M 1993 Growth inhibition and differentiation of HT-29 cells in vitro by inositol hexaphosphate (phytic acid). Caranogenesis 14: 1815-1819
    • (1993) Caranogenesis , vol.14 , pp. 1815-1819
    • Sakamoto, K.1    Venkatraman, G.2    Shamsuddin, A.M.3
  • 34
    • 0027340038 scopus 로고
    • 3HĆ-Phytic acid (inositol hexaphosphate) is absorbed and distributed to various tissues in rats
    • 3HĆ-Phytic acid (inositol hexaphosphate) is absorbed and distributed to various tissues in rats. J Nutr 123: 713-720
    • (1993) J Nutr , vol.123 , pp. 713-720
    • Sakamoto, K.1    Vučenik, I.2    Shamsuddin, A.M.3
  • 36
    • 0028809234 scopus 로고
    • Inositol phosphates have novel anticancer function
    • SHAMSUDDIN A M 1995 Inositol phosphates have novel anticancer function. J Nutr 125: 725S-732S
    • (1995) J Nutr , vol.125
    • Shamsuddin, A.M.1
  • 37
    • 0026780284 scopus 로고
    • Effect of inositol hexaphosphate on growth and differentiation in K-562 erythroleukemia cell line
    • SHAMSUDDIN A M, BATEN A, LALWANI N D 1992 Effect of inositol hexaphosphate on growth and differentiation in K-562 erythroleukemia cell line. Cancer Lett 64: 195-202
    • (1992) Cancer Lett , vol.64 , pp. 195-202
    • Shamsuddin, A.M.1    Baten, A.2    Lalwani, N.D.3
  • 38
    • 0023936256 scopus 로고
    • Suppression of large intestinal cancer in F344 rats by inositol hexaphosphate
    • SHAMSUDDIN A M, ELSAYED A, ULLAH A 1988 Suppression of large intestinal cancer in F344 rats by inositol hexaphosphate. Carcinogenesis 9: 577-580
    • (1988) Carcinogenesis , vol.9 , pp. 577-580
    • Shamsuddin, A.M.1    Elsayed, A.2    Ullah, A.3
  • 39
    • 0024517059 scopus 로고
    • Inositol hexaphosphate inhibits large intestinal cancer in F344 rats 5 months after induction by azoxymethane
    • SHAMSUDDIN A M, ULLAH A 1989 Inositol hexaphosphate inhibits large intestinal cancer in F344 rats 5 months after induction by azoxymethane. Carcinogenesis 10: 625-626
    • (1989) Carcinogenesis , vol.10 , pp. 625-626
    • Shamsuddin, A.M.1    Ullah, A.2
  • 40
    • 0024405693 scopus 로고
    • Inositol and inositol hexaphosphate supresses cell proliferation and tumor formation in CD-1 mice
    • SHAMSUDDIN A M, ULLAH A, CHAKRAVARTHY A 1989 Inositol and inositol hexaphosphate supresses cell proliferation and tumor formation in CD-1 mice. Carcinogenesis 10: 1461-1463
    • (1989) Carcinogenesis , vol.10 , pp. 1461-1463
    • Shamsuddin, A.M.1    Ullah, A.2    Chakravarthy, A.3
  • 41
    • 0029122135 scopus 로고
    • Inositol hexaphosphate inhibits growth and induces differentiation of PC-3 human prostate cancer cells
    • SHAMSUDDIN A M, YANG G 1995 Inositol hexaphosphate inhibits growth and induces differentiation of PC-3 human prostate cancer cells. Carcinogenesis 16: 1975-1979
    • (1995) Carcinogenesis , vol.16 , pp. 1975-1979
    • Shamsuddin, A.M.1    Yang, G.2
  • 42
    • 0030499776 scopus 로고    scopus 로고
    • 6: Growth inhibition and differentiation of human mammary cancer cell lines in vitro
    • 6: Growth inhibition and differentiation of human mammary cancer cell lines in vitro. Anticancer Res 16: 3287-3292
    • (1996) Anticancer Res , vol.16 , pp. 3287-3292
    • Shamsuddin, A.M.1    Yang, G.2    Vučenik, I.3
  • 44
    • 0030020562 scopus 로고    scopus 로고
    • A rapid dual organ rat Carcinogenesis bioassay for evaluating the chemoprevention of breast and colon cancer
    • SHIVAPURKAR N, TANG Z C, FROST A, ALABASTER O 1996 A rapid dual organ rat Carcinogenesis bioassay for evaluating the chemoprevention of breast and colon cancer Cancer Lett 100: 169-179
    • (1996) Cancer Lett , vol.100 , pp. 169-179
    • Shivapurkar, N.1    Tang, Z.C.2    Frost, A.3    Alabaster, O.4
  • 46
    • 0028202201 scopus 로고
    • Inventory of exogenous factors affecting platelet aggregation isolated from plant sources
    • TENG C-M, KO F-N, YU S-M 1994 Inventory of exogenous factors affecting platelet aggregation isolated from plant sources. Thromb Hemostasis 71: 517-519
    • (1994) Thromb Hemostasis , vol.71 , pp. 517-519
    • Teng, C.-M.1    Ko, F.-N.2    Yu, S.-M.3
  • 47
    • 0029057410 scopus 로고
    • Interaction between lck and syk family tyrosine kinase in Fc gamma receptor-initiated activation of natural killer cells
    • TING A T, DICK C J, SCHOON R A, KARNITZ L M, ABRAHAM R T, LEIBSON P J 1995 Interaction between lck and syk family tyrosine kinase in Fc gamma receptor-initiated activation of natural killer cells. J Biol Chem 270: 16415-16421
    • (1995) J Biol Chem , vol.270 , pp. 16415-16421
    • Ting, A.T.1    Dick, C.J.2    Schoon, R.A.3    Karnitz, L.M.4    Abraham, R.T.5    Leibson, P.J.6
  • 48
    • 0026053068 scopus 로고
    • Phytic acid and minerals: Effect on early markers of risk for mammary and colon carcinogenesis
    • THOMPSON L U, ZHANG L 1991 Phytic acid and minerals: effect on early markers of risk for mammary and colon carcinogenesis. Carcinogenesis 12: 2041-2045
    • (1991) Carcinogenesis , vol.12 , pp. 2041-2045
    • Thompson, L.U.1    Zhang, L.2
  • 49
    • 0016799232 scopus 로고
    • Dietary hypothesis of the etiology of diabetes mellitus
    • TROWELL H C 1975 Dietary hypothesis of the etiology of diabetes mellitus. Diabetes 24: 762-765
    • (1975) Diabetes , vol.24 , pp. 762-765
    • Trowell, H.C.1
  • 50
    • 0025612325 scopus 로고
    • Dose-dependent inhibition of large intestinal cancer by inositol hexaphosphate in F344 rats
    • ULLAH A, SHAMSUDDIN A M 1990 Dose-dependent inhibition of large intestinal cancer by inositol hexaphosphate in F344 rats. Carcinogenesis 11: 2219-2222
    • (1990) Carcinogenesis , vol.11 , pp. 2219-2222
    • Ullah, A.1    Shamsuddin, A.M.2
  • 51
    • 0027761183 scopus 로고
    • Inhibition of mammary carcinogenesis by inositol hexaphosphate (phytic acid). A pilot study
    • VUČENIK I, SAKAMOTO K, BANSAL M, SHAMSUDDIN A M 1993 Inhibition of mammary carcinogenesis by inositol hexaphosphate (phytic acid). A pilot study. Cancer Lett 75: 95-102
    • (1993) Cancer Lett , vol.75 , pp. 95-102
    • Vučenik, I.1    Sakamoto, K.2    Bansal, M.3    Shamsuddin, A.M.4
  • 52
    • 0026658125 scopus 로고
    • Antitumor activity of phytic acid in murine transplanted and metastatic fibrosarcoma
    • VUČENK I, TOMAŽIĆ V J, FABIAN D, SHAMSUDDIN A M 1992 Antitumor activity of phytic acid in murine transplanted and metastatic fibrosarcoma. Cancer Lett 65: 9-13
    • (1992) Cancer Lett , vol.65 , pp. 9-13
    • Vučenk, I.1    Tomažić, V.J.2    Fabian, D.3    Shamsuddin, A.M.4
  • 53
    • 0028182572 scopus 로고
    • 3H]-Inositol hexaphosphate is rapidly absorbed and metabolized by murine and human malignant cells in vitro
    • 3H]-Inositol hexaphosphate is rapidly absorbed and metabolized by murine and human malignant cells in vitro. J Nutr 124: 861-868
    • (1994) J Nutr , vol.124 , pp. 861-868
    • Vučenik, I.1    Shamsuddin, A.M.2
  • 54
    • 0029057655 scopus 로고
    • Inositol hexaphosphate and inositol inhibit DMBA-induced rat mammary cancer
    • VUČENIK I, YANG G, SHAMSUDDIN A M 1995 Inositol hexaphosphate and inositol inhibit DMBA-induced rat mammary cancer. Carcinogenesis 16: 1055-1058
    • (1995) Carcinogenesis , vol.16 , pp. 1055-1058
    • Vučenik, I.1    Yang, G.2    Shamsuddin, A.M.3
  • 55
    • 25344472118 scopus 로고
    • 6 is more effective than high bran diet in inhibiting DMBA-rat mammary carcinogenesis
    • 6 is more effective than high bran diet in inhibiting DMBA-rat mammary carcinogenesis. FASEB J 9: A728
    • (1995) FASEB J , vol.9
    • Vučenik, I.1    Yang, G.2    Shamsuddin, A.M.3
  • 56
    • 0030855536 scopus 로고    scopus 로고
    • 6) and high-bran diet in the prevention of DMBA-induced rat mammary carcinogenesis
    • 6) and high-bran diet in the prevention of DMBA-induced rat mammary carcinogenesis. Nutrition and Cancer 28: 7-13
    • (1997) Nutrition and Cancer , vol.28 , pp. 7-13
    • Vučenik, I.1    Yang, G.2    Shamsuddin, A.M.3
  • 60
    • 0029415212 scopus 로고
    • 6-induced growth inhibition and differentiation of HT-29 human colon career cells: Involvement of intracellular inositol phosphates
    • 6-induced growth inhibition and differentiation of HT-29 human colon career cells: Involvement of intracellular inositol phosphates. Anticancer Res 15: 2479-2488
    • (1995) Anticancer Res , vol.15 , pp. 2479-2488
    • Yang, G.1    Shamsuddin, A.M.2
  • 61
    • 0025758395 scopus 로고
    • Comparative epidemiology of cancers of the colon, rectum, prostate and breast in Shanghai, China versus the United States
    • YU H, HARRIS R E, GAO Y-T, GAO R, WYNDER E L 1991 Comparative epidemiology of cancers of the colon, rectum, prostate and breast in Shanghai, China versus the United States. Int J Epidemiol 20: 76-81
    • (1991) Int J Epidemiol , vol.20 , pp. 76-81
    • Yu, H.1    Harris, R.E.2    Gao, Y.-T.3    Gao, R.4    Wynder, E.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.