Hidden chromosome abnormalities in haematological malignancies detected by multicolour spectral karyotyping

Nature Genetics

Volumn 15, Issue 4, 1997, Pages 406-410

  Veldman, Tim ^a   Vignon, Christine ^b   Schröck, Evelin ^a   Rowley, Janet D ^b   Ried, Thomas ^a  

^a NATIONAL HUMAN GENOME RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CHROMOSOME ABERRATION; CHROMOSOME BANDING PATTERN; CHROMOSOME REARRANGEMENT; CHROMOSOME TRANSLOCATION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; KARYOTYPING; LEUKEMIA; LYMPHOMA; MALE; METAPHASE CHROMOSOME; MYELODYSPLASTIC SYNDROME; PRIORITY JOURNAL;

ADULT; AGED; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; CHROMOSOME BANDING; CHROMOSOME DISORDERS; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; LEUKEMIA; LYMPHOMA; MALE; MIDDLE AGED;

EID: 0030909689     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng0497-406     Document Type: Article

References (14)

1. Sandberg, A.A. The chromosomes in human cancer and leukemia (Elsevier, New York, 1990).
2. Heim, S. & Mitelman, F. Cancer Cytogenetics (Wiley-Liss, New York, 1995).
3. Rowley, J.D. The Philadelphia chromosome translocation. A paradigm for understanding leukemia. Cancer 65, 2178-2184 (1990).
4. Rabbitts, T.H. Chromosomal translocations in human cancer. Nature 372, 143-149 (1994).
5. Le Beau, M.M. Detecting genetic changes in human tumor cells: have scientists "gone fishing?" Blood 81, 1979-1983 (1993).
6. Schröck, E. et al. Multicolor spectral karyotyping of human chromosomes. Science 273, 494-497 (1996).
7. Liyanage, M. et al. Multicolour spectral karyotyping of mouse chromosomes. Nature Genet 14, 312-315 (1996).
8. LeBeau, M.M. et al. Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 7 in malignant myeloid diseases. Blood, 88, 1930-1935 (1996).
9. Romana, S.P., Le Coniat, M. & Berger, R. t(12;21): a new recurrent translocation in acute lymphoblastic leukemia. Genes Chromosom. Cancer 9, 186-191 (1994).
10. Speicher, M., Ballard, S.G. & Ward, D.C. Karyotyping human chromosome by combinatorial multi-fluor FISH. Nature Genet. 12, 368-375 (1996).
11. LeBeau, M.M. Cytogenetic analysis of hematologic malignant disease. In Association of Cytogenetics Technologists, Technical Manual. (ed. Barch, M.A.) 95-149 (Raven Press, New York, 1991).
12. Telenius, H. et al. Cytogenetic analysis by chromosome painting using DOP-PCR amplified flow sorted chromosomes. Genes Chromosom. Cancer 4, 257-263 (1992).
13. Malik, Z. et al. Fourier transform multipixel spectroscopy for quantitative cytology. J. Microscopy 182, 133-140 (1996).
14. Garini, Y. et al. Spectral karyotyping. Bioimaging 4, 65-72 (1996).