The Skin Irritation Corrosion Rules Estimation Tool (SICRET)

QSAR and Combinatorial Science

Volumn 24, Issue 3, 2005, Pages 378-384

  Walker, John D ^a   Gerner, Ingrid ^b   Hulzebos, Etje ^c   Schlegel, Kerstin ^b  

^a U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

^b FEDERAL INSTITUTE FOR RISK ASSESSMENT   (Germany)

^c NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

Author keywords

Physicochemical Properties; Skin Corrosion; Skin Irritation; Structural Alerts

Indexed keywords

FEEDBACK; INDICATORS (CHEMICAL); PHYSICOCHEMICAL PROPERTIES;

ESTIMATION TOOLS; FEEDBACK LOOPS; IN-VITRO; IN-VITRO TESTING; IN-VITRO TESTS; PHYSICOCHEMICAL PROPERTY; SKIN CORROSION; SKIN IRRITATION; STRUCTURAL ALERT; TOOL USE;

STRUCTURAL PROPERTIES;

ACID; ACID ANHYDRIDE; ACRYLIC ACID DERIVATIVE; ALDEHYDE; ALKANOL; ALKYNE; AROMATIC AMINE; BENZENE DERIVATIVE; BENZYL DERIVATIVE; CATECHOL DERIVATIVE; EPOXIDE; ETHYLENE GLYCOL DERIVATIVE; HALOGENATED HYDROCARBON; HYDROPEROXIDE; HYDROQUINONE DERIVATIVE; IMIDE; KETENE DERIVATIVE; KETONE DERIVATIVE; LACTAM DERIVATIVE; LACTONE; METHACRYLIC ACID DERIVATIVE; NITROBENZENE DERIVATIVE; PHENOL DERIVATIVE; PHOSPHONIUM DERIVATIVE; QUATERNARY AMMONIUM DERIVATIVE; QUINONE DERIVATIVE; RESORCINOL DERIVATIVE; THIOAMIDE;

ARTICLE; BURN; CORROSION; DATA BASE; DECISION SUPPORT SYSTEM; EUROPEAN UNION; HUMAN; IN VITRO STUDY; MELTING POINT; MOLECULAR WEIGHT; PHYSICAL CHEMISTRY; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; RISK ASSESSMENT; SAFETY; SKIN CORROSION; SKIN IRRITATION; SKIN IRRITATION CORROSION RULES ESTIMATION TOOL;

ANIMALIA;

EID: 18344375332     PISSN: 1611020X     EISSN: None     Source Type: Journal    
DOI: 10.1002/qsar.200430906     Document Type: Article

References (24)

1. J. L. M. Hermens, A. Opperhuizen, QSAR in Environmental Toxicology - IV, Elsevier, The Netherlands, 1991.
2. J. D. Walker, Sci Total Environ. 1991, 109/110, 691-700.
3. G. Patlewicz, D. W. Roberts, J. D. Walker, QSAR Comb. Sci. 2003, 22, 196-203.
4. E. M. Hulzebos, L. Maslankiewicz, J. D. Walker, QSAR Comb. Sci. 2003, 22, 351-363.
5. I. Gerner, E. Schlede, Toxicol. Lett. 2002, 127, 169-175.
6. I. Gerner, G. Graetschel, J. Kahl, E. Schlede, ATLA 2000, 23, 11-28.
7. I. Gerner, S. Zinke, G. Graetschel, E. Schlede, ATLA 2000, 25, 665-698.
8. S. Zinke, I. Gerner, ATLA 2000, 28, 651-663.
9. S. Zinke, I. Gerner, G. Graetschel, E. Schlede, ATLA 2000, 25, 29-40.
10. J. D. Walker, I. Gerner, E. T. Hulzebos, K. Schlegel, QSAR Comb. Sci. (accepted).
11. M. D. Barratt, ATLA 1995, 2, 219-255.
12. M. D. Barratt, Toxicol. in Vitro 1995, 9, 27-37.
13. M. D. Barratt, Toxicol. Lett. 1995, 75, 169-176.
14. M. D. Barratt, Toxicol. in Vitro 1996, 10, 85-94.
15. M. D. Barratt, Toxicol. in Vitro 1996, 10, 247-256.
16. M. D. Barratt. Environ. Health Perspect. 1998, 106 (Suppl. 2), 459-465.
17. M. D. Barratt, Predicting of skin corrosivity using quantitative structure-activity relationships, in: H. I. Maybach (Ed.), Toxicology of Skin, Taylor & Francis, Philadelphia, PA, 2001, pp. 115-120.
18. H. Hayashi, Y. Nakamura, K. Higashi, H. Kato, F. Kishida, H. Kaneko, Toxicol. In Vitro 1999, 13, 915-922.
19. J. S. Smith, O. T. Macina, N. B. Sussman, M. I. Luster, M. H. Karol, Toxicol. Sci. 2000, 55, 215-222.
20. J. S. Smith O. T. Macina N. B. Sussman, M. H. Karol, H. I. Maibach, Quant. Struct.-Act. Relat. 2000, 19, 467-474.
21. I. Gerner, J. D. Walker, E. T. Hulzebos, K. Schlegel, QSAR Comb. Sci. (accepted).
22. E. T. Hulzebos, J. D. Walker, I. Gerner, K. Schlegel, QSAR Comb. Sci. (accepted).
23. J. D. Walker, QSARs for Toxicity Screening - Current Practices, in: J. D. Walker (Ed.), QSARs for Pollution Prevention, Toxicity Screening, Risk Assessment and Web Applications, SETAC Press, Pensacola, FL, 2003, pp. 39-74.
24. J. C. Dearden, Environ. Toxicol. Chem. 2003, 22, 1696-1709.