Role of ETA receptors in the vasoconstriction induced by endothelin-1 in subcutaneous small arteries of normotensive subjects and hypertensive patients

Blood Pressure

Volumn 11, Issue 1, 2002, Pages 6-12

  Porteri, Enzo ^a   Rizzoni, Damiano ^a   Guelfi, Daniele ^a   De Ciuceis, Carolina ^a   Castellano, Maurizio ^a   Bettoni, Giorgio ^a   Tiberio, Guido A M ^a   Giulini, Stefano M ^a   Sleiman, Intissar ^a   Agabiti Rosei, Enrico ^a  

^a UNIVERSITY OF BRESCIA   (Italy)

Author keywords

Endothelin; Endothelium; Vascular remodelling; Vascular resistance

Indexed keywords

2 [[2 [[2 [[(HEXAHYDRO 1H AZEPIN 1 YL)CARBONYL]AMINO] 4 METHYLPENTANOYL]AMINO] 3 (1 METHYL 1H INDOL 3 YL)PROPIONYL]AMINO] 3 (2 PYRIDYL)PROPIONIC ACID; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; NITRIC OXIDE; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR;

ADULT; ARTERY DIAMETER; ARTERY RESISTANCE; ARTICLE; CLINICAL ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ESSENTIAL HYPERTENSION; FEMALE; HUMAN; HUMAN TISSUE; MALE; MYOGRAPHY; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; SUBCUTANEOUS FAT; TECHNIQUE; VASCULAR SMOOTH MUSCLE; VASOCONSTRICTION; VASODILATATION; ADIPOSE TISSUE; ARTERY; CASE CONTROL STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; HYPERTENSION; MIDDLE AGED; PATHOPHYSIOLOGY; PHYSIOLOGY; VASCULARIZATION;

ADIPOSE TISSUE; ARTERIES; CASE-CONTROL STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIN-1; FEMALE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; RECEPTOR, ENDOTHELIN A; RECEPTOR, ENDOTHELIN B; RECEPTORS, ENDOTHELIN; VASOCONSTRICTION;

EID: 18344366529     PISSN: 08037051     EISSN: None     Source Type: Journal    
DOI: 10.1080/080370502753543891     Document Type: Article

References (45)

1. A novel potent vasoconstrictor peptide produced by vascular endothelial cells
2. The endothelin family: An overview
3. Plasma endothelin concentrations in hypertension
4. Potential role of endothelin in hypertension Controversy on endothelin in hypertension
5. Is endothelin involved in the pathogenesis of hypertension?
6. Endothelin: Role in experimental hypertension
7. Enhanced expression of endothelin-1 gene in severe human essential hypertension
8. Endogenous endothelin generation maintains vascular tone in humans
9. A receptors predominate in the human vasculature and mediate constriction
10. Modulation of contractions to and receptors for endothelins in canine veins
11. Characterization of receptors for endothelins in the guinea pig mesenteric vasculature
12. B receptor antagonists PD145065 on arteries, arterioles and veins in the cat hindlimbs
13. B receptors in the arterial vasculature of the isolated canine liver
14. Endothelin receptor subtypes in small arteries. Studies with FR139317 and bosentan
15. Endothelial receptor subtypes in resistance arteries from humans and rats
16. Endothelin receptors mediating vasoconstriction in rat pressurized small arteries
17. B receptors mediate contraction to endothelin-1 in renal artery of aging SHR. Effects of FR139317 and bosentan
18. The vasocontriction induced by endothelin-1 is mediated only by ETA receptors in mesenteric small resistance arteries of spontaneously hypertensive rats
19. 1999 World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension
20. Evidence for increased media thickness, increased neural amine uptake, and depressed excitation-contraction coupling in isolated resistance vessels from essential hypertensives
21. Abnormal structure and function of isolated subcutaneous resistance vessels from essential hypertensive patients despite anti-hypertensive treatment
22. Contractile properties of small resistance vessels in spontaneously hypertensive and normotensive rats
23. Direct evidence that the greater contractility of resistance vessels in spontaneously hypertensive rats is associated with a narrowed lumen, a thickened media, and an increased number of smooth muscle cell layers
24. Prolonged endothelin blockade prevents hypertension and cardiac hypertrophy in stroke-prone spontaneously hypertensive rats
25. Evidence that ET-1 but not ET-3 and S6b, ET(A)-receptor mediated contractions in isolated rat mesenteric arteries are modulated by co-activation of ET(B) receptors
26. Inotropic effects of endothelin compared to noradrenaline in porcine myocardial trabeculae
27. Endothelin receptor mediating contraction of isolated bovine coronary artery
28. Endothelin ET(B1) receptor-mediated relaxation of rabbit basilar artery
29. Characterisation of constrictor endothelin receptors in the human internal thoracic artery and saphenous vein
30. Endothelin-1 stimulates proliferation of human coronary smooth muscle cells via the ET(A) receptor and is comitogenic with growth factors
31. B receptor
32. Delayed development of hypertension after short-term nitrendipine treatment
33. Vascular hypertrophy and remodeling in secondary hypertension
34. Interactions between nitric oxide and endothelin in the regulation of vascular tone of human resistance vessels in vivo
35. Role for endothelin-1 in angiotensin II mediated hypertension
36. A-receptor blockade in angiotensin II induced hypertension
37. Endothelin in hypertensive resistance arteries: Intraluminal and extraluminal dysfunction
38. Endothelin sensitivity and receptor binding in aorta of spontaneously hypertensive rats
39. Effect of antihypertensive treatment on response to endothelin of resistance arteries of hypertensive rats
40. In vitro vascular reactivity to endothelin: A comparison between young and old normotensive and hypertensive rats
41. Differential effects of vasopressin and endothelin-1 on vascular contractile and calcium responses in pressurized small arteries from spontaneously hypertensive rats
42. Effects of endothelin-1 and vasopressin on resistance arteries of spontaneously hypertensive rats
43. Endothelin-1 receptor mediated responses in resistance vessels of young and adult spontaneously hypertensive rats
44. Functional characterization of endothelin receptors in hypertensive resistance vessels
45. Selective increase of the contractile response to endothelin-1 in subcutaneous arteries form patients with essential hypertension