메뉴 건너뛰기




Volumn 99, Issue 6, 2005, Pages 683-694

Effects of dual therapy with corticosteroids plus long acting β 2-agonists in asthma

Author keywords

Asthma; Bronchial hyperresponsiveness; Budesonide; Eformoterol; Fluticasone; Inflammation; Leukotriene receptor antagonist; Long acting 2 agonist; Montelukast; Randomised controlled trial; Salmeterol; Seretide; Symbicort; Theophylline; Zafirlukast

Indexed keywords

BECLOMETASONE; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; BUDESONIDE; BUDESONIDE PLUS FORMOTEROL; CORTICOSTEROID; FLUTICASONE; FLUTICASONE PROPIONATE PLUS SALMETEROL; FORMOTEROL; GLUCOCORTICOID RECEPTOR; LEUKOTRIENE RECEPTOR; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LIPOXYGENASE INHIBITOR; LONG ACTING DRUG; METHACHOLINE; MONTELUKAST; NITRIC OXIDE; PLACEBO; SALMETEROL; SHORT ACTING DRUG; TERBUTALINE; THEOPHYLLINE; TRIAMCINOLONE; ZAFIRLUKAST;

EID: 18244408226     PISSN: 09546111     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmed.2004.11.008     Document Type: Article
Times cited : (15)

References (70)
  • 1
    • 3042626941 scopus 로고    scopus 로고
    • Does bronchial hyperresponsiveness in asthma matter?
    • G.P. Currie C.M. Jackson B.J. Lipworth Does bronchial hyperresponsiveness in asthma matter? J Asthma 41 2004 247-258
    • (2004) J. Asthma , vol.41 , pp. 247-258
    • Currie, G.P.1    Jackson, C.M.2    Lipworth, B.J.3
  • 2
    • 0032558685 scopus 로고    scopus 로고
    • A 15-year follow-up study of ventilatory function in adults with asthma
    • P. Lange J. Parner J. Vestbo P. Schnohr G. Jensen A 15-year follow-up study of ventilatory function in adults with asthma N Engl J Med 339 1998 1194-1200
    • (1998) N. Engl. J. Med. , vol.339 , pp. 1194-1200
    • Lange, P.1    Parner, J.2    Vestbo, J.3    Schnohr, P.4    Jensen, G.5
  • 3
    • 0029979652 scopus 로고    scopus 로고
    • Mortality in adults with self-reported asthma
    • Copenhagen City Heart Study Group
    • P. Lange C.S. Ulrik J. Vestbo Mortality in adults with self-reported asthma. Copenhagen City Heart Study Group Lancet 347 1996 1285-1289
    • (1996) Lancet , vol.347 , pp. 1285-1289
    • Lange, P.1    Ulrik, C.S.2    Vestbo, J.3
  • 4
    • 0031023695 scopus 로고    scopus 로고
    • Mortality of adults with asthma: A prospective cohort study
    • E. Huovinen J. Kaprio E. Vesterinen M. Koskenvuo Mortality of adults with asthma: A prospective cohort study Thorax 52 1997 49-54
    • (1997) Thorax , vol.52 , pp. 49-54
    • Huovinen, E.1    Kaprio, J.2    Vesterinen, E.3    Koskenvuo, M.4
  • 6
    • 0037313809 scopus 로고    scopus 로고
    • British guideline on the management of asthma
    • British guideline on the management of asthma Thorax 58 Suppl 1 2003 i1-i94
    • (2003) Thorax , vol.58 , Issue.SUPPL. 1
  • 8
    • 0030958324 scopus 로고    scopus 로고
    • Effect of short-term treatment with low-dose inhaled fluticasone propionate on airway inflammation and remodeling in mild asthma: A placebo-controlled study
    • D. Olivieri A. Chetta M. Del Donno et al. Effect of short-term treatment with low-dose inhaled fluticasone propionate on airway inflammation and remodeling in mild asthma: A placebo-controlled study Am J Respir Crit Care Med 155 1997 1864-1871
    • (1997) Am. J. Respir. Crit. Care Med. , vol.155 , pp. 1864-1871
    • Olivieri, D.1    Chetta, A.2    Del Donno, M.3
  • 9
    • 0028240265 scopus 로고
    • Placebo-controlled immunopathologic study of four months of inhaled corticosteroids in asthma
    • C.J. Trigg N.D. Manolitsas J. Wang et al. Placebo-controlled immunopathologic study of four months of inhaled corticosteroids in asthma Am J Respir Crit Care Med 150 1994 17-22
    • (1994) Am. J. Respir. Crit. Care Med. , vol.150 , pp. 17-22
    • Trigg, C.J.1    Manolitsas, N.D.2    Wang, J.3
  • 10
    • 0035806738 scopus 로고    scopus 로고
    • Dose-response relation of inhaled fluticasone propionate in adolescents and adults with asthma: Meta-analysis
    • S. Holt A. Suder M. Weatherall S. Cheng P. Shirtcliffe R. Beasley Dose-response relation of inhaled fluticasone propionate in adolescents and adults with asthma: Meta-analysis BMJ 323 2001 253-256
    • (2001) BMJ , vol.323 , pp. 253-256
    • Holt, S.1    Suder, A.2    Weatherall, M.3    Cheng, S.4    Shirtcliffe, P.5    Beasley, R.6
  • 11
    • 0037327325 scopus 로고    scopus 로고
    • Dose response of inhaled corticosteroids on bronchial hyperresponsiveness: A meta-analysis
    • G.P. Currie S.J. Fowler B.J. Lipworth Dose response of inhaled corticosteroids on bronchial hyperresponsiveness: A meta-analysis Ann Allergy Asthma Immunol 90 2003 194-198
    • (2003) Ann. Allergy Asthma Immunol. , vol.90 , pp. 194-198
    • Currie, G.P.1    Fowler, S.J.2    Lipworth, B.J.3
  • 12
    • 4544388874 scopus 로고    scopus 로고
    • Effect of high dose inhaled fluticasone propionate on the hypothalamic-pituitary-adrenal axis in asthmatics with severely impaired lung function
    • D.K.C. Lee C.E. Bates G.P. Currie L.M. Cowan L.C. Mcfarlane B.J. Lipworth Effect of high dose inhaled fluticasone propionate on the hypothalamic-pituitary-adrenal axis in asthmatics with severely impaired lung function Chest 93 2004 253-258
    • (2004) Chest , vol.93 , pp. 253-258
    • Lee, D.K.C.1    Bates, C.E.2    Currie, G.P.3    Cowan, L.M.4    Mcfarlane, L.C.5    Lipworth, B.J.6
  • 13
    • 0034641584 scopus 로고    scopus 로고
    • Comparison of pharmacokinetics and systemic effects of inhaled fluticasone propionate in patients with asthma and healthy volunteers: A randomised crossover study
    • M.H. Brutsche I.C. Brutsche M. Munawar et al. Comparison of pharmacokinetics and systemic effects of inhaled fluticasone propionate in patients with asthma and healthy volunteers: A randomised crossover study Lancet 356 2000 556-561
    • (2000) Lancet , vol.356 , pp. 556-561
    • Brutsche, M.H.1    Brutsche, I.C.2    Munawar, M.3
  • 14
    • 0033542041 scopus 로고    scopus 로고
    • Systemic adverse effects of inhaled corticosteroid therapy: A systematic review and meta-analysis
    • B.J. Lipworth Systemic adverse effects of inhaled corticosteroid therapy: A systematic review and meta-analysis Arch Int Med 159 1999 941-955
    • (1999) Arch. Int. Med. , vol.159 , pp. 941-955
    • Lipworth, B.J.1
  • 15
    • 0032419991 scopus 로고    scopus 로고
    • Dose-response to inhaled corticosteroids: Benefits and risks
    • B.J. Lipworth A.M. Wilson Dose-response to inhaled corticosteroids: benefits and risks Sem Respir Crit Care Med 19 1998 625-646
    • (1998) Sem. Respir. Crit. Care Med. , vol.19 , pp. 625-646
    • Lipworth, B.J.1    Wilson, A.M.2
  • 16
    • 0037945159 scopus 로고    scopus 로고
    • Airway-stabilizing effect of long-acting beta2-agonists as add-on therapy to inhaled corticosteroids
    • G.P. Currie C.M. Jackson S.A. Ogston B.J. Lipworth Airway-stabilizing effect of long-acting beta2-agonists as add-on therapy to inhaled corticosteroids QJM 96 2003 435-440
    • (2003) QJM , vol.96 , pp. 435-440
    • Currie, G.P.1    Jackson, C.M.2    Ogston, S.A.3    Lipworth, B.J.4
  • 17
    • 0028057265 scopus 로고
    • Formoterol on airway smooth muscle and human lung mast cells: A comparison with salbutamol and salmeterol
    • A.T. Nials D.I. Ball P.R. Butchers et al. Formoterol on airway smooth muscle and human lung mast cells: A comparison with salbutamol and salmeterol Eur J Pharmacol 251 1994 127-135
    • (1994) Eur. J. Pharmacol. , vol.251 , pp. 127-135
    • Nials, A.T.1    Ball, D.I.2    Butchers, P.R.3
  • 18
    • 0031883632 scopus 로고    scopus 로고
    • Salmeterol inhibition of mediator release from human lung mast cells by beta-adrenoceptor-dependent and independent mechanisms
    • L.K. Chong E. Cooper C.J. Vardey P.T. Peachell Salmeterol inhibition of mediator release from human lung mast cells by beta-adrenoceptor-dependent and independent mechanisms Br J Pharmacol 123 1998 1009-1015
    • (1998) Br. J. Pharmacol. , vol.123 , pp. 1009-1015
    • Chong, L.K.1    Cooper, E.2    Vardey, C.J.3    Peachell, P.T.4
  • 19
    • 0026075715 scopus 로고
    • Long duration and high potency of antiexudative effects of formoterol in guinea-pig tracheobronchial airways
    • I. Erjefalt C.G. Persson Long duration and high potency of antiexudative effects of formoterol in guinea-pig tracheobronchial airways Am Rev Respir Dis 144 1991 788-791
    • (1991) Am. Rev. Respir. Dis. , vol.144 , pp. 788-791
    • Erjefalt, I.1    Persson, C.G.2
  • 20
    • 0030896245 scopus 로고    scopus 로고
    • Salmeterol reduces early and late-phase plasma leakage and leukocyte adhesion in rat airways
    • P.B. Bolton P. Lefevre D.M. McDonald Salmeterol reduces early and late-phase plasma leakage and leukocyte adhesion in rat airways Am J Respir Crit Care Med 155 1997 1428-1435
    • (1997) Am. J. Respir. Crit. Care Med. , vol.155 , pp. 1428-1435
    • Bolton, P.B.1    Lefevre, P.2    McDonald, D.M.3
  • 21
    • 0027418737 scopus 로고
    • Beta 2-adrenoceptor agonists inhibit NANC neural bronchoconstrictor responses in vitro
    • G.M. Verleden M.G. Belvisi K.F. Rabe M. Miura P.J. Barnes Beta 2-adrenoceptor agonists inhibit NANC neural bronchoconstrictor responses in vitro J Appl Physiol 74 1993 1195-1199
    • (1993) J. Appl. Physiol. , vol.74 , pp. 1195-1199
    • Verleden, G.M.1    Belvisi, M.G.2    Rabe, K.F.3    Miura, M.4    Barnes, P.J.5
  • 22
    • 0041385624 scopus 로고    scopus 로고
    • Long-acting beta(2)-agonists: Comparative pharmacology and clinical outcomes
    • H.J. Van Der Woude R. Aalbers Long-acting beta(2)-agonists: Comparative pharmacology and clinical outcomes Am J Respir Med 1 2002 55-74
    • (2002) Am. J. Respir. Med. , vol.1 , pp. 55-74
    • Van Der Woude, H.J.1    Aalbers, R.2
  • 23
    • 0028300203 scopus 로고
    • Why are long-acting beta-adrenoceptor agonists long-acting?
    • G.P. Anderson A. Linden K.F. Rabe Why are long-acting beta-adrenoceptor agonists long-acting? Eur Respir J 7 1994 569-578
    • (1994) Eur. Respir. J , vol.7 , pp. 569-578
    • Anderson, G.P.1    Linden, A.2    Rabe, K.F.3
  • 24
    • 0032793507 scopus 로고    scopus 로고
    • Comparison of the relative efficacy of formoterol and salmeterol in asthmatic patients
    • M. Palmqvist T. Ibsen A. Mellen J. Lotvall Comparison of the relative efficacy of formoterol and salmeterol in asthmatic patients Am J Respir Crit Care Med 160 1999 244-249
    • (1999) Am. J. Respir. Crit. Care Med. , vol.160 , pp. 244-249
    • Palmqvist, M.1    Ibsen, T.2    Mellen, A.3    Lotvall, J.4
  • 25
    • 0035956698 scopus 로고    scopus 로고
    • Comparison of formoterol and terbutaline for as-needed treatment of asthma: A randomised trial
    • A.E. Tattersfield C.G. Lofdahl D.S. Postma et al. Comparison of formoterol and terbutaline for as-needed treatment of asthma: A randomised trial Lancet 357 2001 257-261
    • (2001) Lancet , vol.357 , pp. 257-261
    • Tattersfield, A.E.1    Lofdahl, C.G.2    Postma, D.S.3
  • 26
    • 0032589395 scopus 로고    scopus 로고
    • The long-acting beta2-agonist salmeterol xinafoate: Effects on airway inflammation in asthma
    • J.A. Roberts P. Bradding K.M. Britten et al. The long-acting beta2-agonist salmeterol xinafoate: Effects on airway inflammation in asthma Eur Respir J 14 1999 275-282
    • (1999) Eur. Respir. J , vol.14 , pp. 275-282
    • Roberts, J.A.1    Bradding, P.2    Britten, K.M.3
  • 28
    • 0035065409 scopus 로고    scopus 로고
    • The effect of salmeterol on markers of airway inflammation following segmental allergen challenge
    • W.J. Calhoun K.L. Hinton J.J. Kratzenberg The effect of salmeterol on markers of airway inflammation following segmental allergen challenge Am J Respir Crit Care Med 163 2001 881-886
    • (2001) Am. J. Respir. Crit. Care Med. , vol.163 , pp. 881-886
    • Calhoun, W.J.1    Hinton, K.L.2    Kratzenberg, J.J.3
  • 29
    • 0035938606 scopus 로고    scopus 로고
    • Long-acting beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma: A randomized controlled trial
    • S.C. Lazarus H.A. Boushey J.V. Fahy et al. Long-acting beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients with persistent asthma: A randomized controlled trial JAMA 285 2001 2583-2593
    • (2001) JAMA , vol.285 , pp. 2583-2593
    • Lazarus, S.C.1    Boushey, H.A.2    Fahy, J.V.3
  • 30
    • 0342419450 scopus 로고    scopus 로고
    • Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: A randomized controlled trial
    • R.F. Lemanske Jr C.A. Sorkness E.A. Mauger et al. Inhaled corticosteroid reduction and elimination in patients with persistent asthma receiving salmeterol: A randomized controlled trial JAMA 285 2001 2594-2603
    • (2001) JAMA , vol.285 , pp. 2594-2603
    • Lemanske, R.F.1    Sorkness, C.A.2    Mauger, E.A.3
  • 31
    • 0031663235 scopus 로고    scopus 로고
    • Subsensitivity to bronchoprotection against adenosine monophosphate challenge following regular once-daily formoterol
    • I. Aziz K.S. Tan I.P. Hall M.M. Devlin B.J. Lipworth Subsensitivity to bronchoprotection against adenosine monophosphate challenge following regular once-daily formoterol Eur Respir J 12 1998 580-584
    • (1998) Eur. Respir. J , vol.12 , pp. 580-584
    • Aziz, I.1    Tan, K.S.2    Hall, I.P.3    Devlin, M.M.4    Lipworth, B.J.5
  • 32
    • 0028226021 scopus 로고
    • Reduced protection against exercise induced bronchoconstriction after chronic dosing with salmeterol
    • L. Ramage B.J. Lipworth C.G. Ingram I.A. Cree D.P. Dhillon Reduced protection against exercise induced bronchoconstriction after chronic dosing with salmeterol Respir Med 88 1994 363-368
    • (1994) Respir. Med. , vol.88 , pp. 363-368
    • Ramage, L.1    Lipworth, B.J.2    Ingram, C.G.3    Cree, I.A.4    Dhillon, D.P.5
  • 33
    • 0032922641 scopus 로고    scopus 로고
    • A high dose of albuterol does not overcome bronchoprotective subsensitivity in asthmatic subjects receiving regular salmeterol or formoterol
    • B.J. Lipworth I. Aziz A high dose of albuterol does not overcome bronchoprotective subsensitivity in asthmatic subjects receiving regular salmeterol or formoterol J Allergy Clin Immunol 103 1999 88-92
    • (1999) J. Allergy Clin. Immunol. , vol.103 , pp. 88-92
    • Lipworth, B.J.1    Aziz, I.2
  • 34
    • 1242351726 scopus 로고    scopus 로고
    • Written action plans for asthma: An evidence-based review of the key components
    • P.G. Gibson H. Powell Written action plans for asthma: An evidence-based review of the key components Thorax 59 2004 94-99
    • (2004) Thorax , vol.59 , pp. 94-99
    • Gibson, P.G.1    Powell, H.2
  • 35
    • 1042279583 scopus 로고    scopus 로고
    • Adjustable maintenance dosing with budesonide/formoterol compared with fixed-dose salmeterol/fluticasone in moderate to severe asthma
    • R. Aalbers V. Backer T.T. Kava et al. Adjustable maintenance dosing with budesonide/formoterol compared with fixed-dose salmeterol/fluticasone in moderate to severe asthma Curr Med Res Opin 20 2004 225-240
    • (2004) Curr. Med. Res. Opin. , vol.20 , pp. 225-240
    • Aalbers, R.1    Backer, V.2    Kava, T.T.3
  • 37
    • 0034105388 scopus 로고    scopus 로고
    • A long-term study of the antiinflammatory effect of low-dose budesonide plus formoterol versus high-dose budesonide in asthma
    • J.C. Kips B.J. O'Connor M.D. Inman K. Svensson R.A. Pauwels P.M. O'Byrne A long-term study of the antiinflammatory effect of low-dose budesonide plus formoterol versus high-dose budesonide in asthma Am J Respir Crit Care Med 161 2000 996-1001
    • (2000) Am. J. Respir. Crit. Care Med. , vol.161 , pp. 996-1001
    • Kips, J.C.1    O'Connor, B.J.2    Inman, M.D.3    Svensson, K.4    Pauwels, R.A.5    O'Byrne, P.M.6
  • 38
    • 0025223381 scopus 로고
    • Regular inhaled beta-agonist treatment in bronchial asthma
    • M.R. Sears D.R. Taylor C.G. Print et al. Regular inhaled beta-agonist treatment in bronchial asthma Lancet 336 1990 1391-1396
    • (1990) Lancet , vol.336 , pp. 1391-1396
    • Sears, M.R.1    Taylor, D.R.2    Print, C.G.3
  • 39
    • 9544253883 scopus 로고    scopus 로고
    • Comparison of regularly scheduled with as-needed use of albuterol in mild asthma
    • Asthma Clinical Research Network
    • J.M. Drazen E. Israel H.A. Boushey et al. Comparison of regularly scheduled with as-needed use of albuterol in mild asthma. Asthma Clinical Research Network N Engl J Med 335 1996 841-847
    • (1996) N. Engl. J. Med. , vol.335 , pp. 841-847
    • Drazen, J.M.1    Israel, E.2    Boushey, H.A.3
  • 40
    • 0034643636 scopus 로고    scopus 로고
    • Regular inhaled salbutamol and asthma control: The TRUST randomised trial
    • Therapy Working Group of the National Asthma Task force and the MRC General Practce Research Framework
    • S.M. Dennis S.J. Sharp M.R. Vickers et al. Regular inhaled salbutamol and asthma control: The TRUST randomised trial. Therapy Working Group of the National Asthma Task force and the MRC General Practce Research Framework Lancet 355 2000 1675-1679
    • (2000) Lancet , vol.355 , pp. 1675-1679
    • Dennis, S.M.1    Sharp, S.J.2    Vickers, M.R.3
  • 41
    • 0034690661 scopus 로고    scopus 로고
    • Meta-analysis of increased dose of inhaled steroid or addition of salmeterol in symptomatic asthma (MIASMA)
    • S. Shrewsbury S. Pyke M. Britton Meta-analysis of increased dose of inhaled steroid or addition of salmeterol in symptomatic asthma (MIASMA) BMJ 320 2000 1368-1373
    • (2000) BMJ , vol.320 , pp. 1368-1373
    • Shrewsbury, S.1    Pyke, S.2    Britton, M.3
  • 42
    • 0035888721 scopus 로고    scopus 로고
    • Low dose inhaled budesonide and formoterol in mild persistent asthma: The OPTIMA randomized trial
    • P.M. O'Byrne P.J. Barnes R. Rodriguez-Roisin et al. Low dose inhaled budesonide and formoterol in mild persistent asthma: The OPTIMA randomized trial Am J Respir Crit Care Med 164 2001 1392-1397
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , pp. 1392-1397
    • O'Byrne, P.M.1    Barnes, P.J.2    Rodriguez-Roisin, R.3
  • 43
    • 0036727059 scopus 로고    scopus 로고
    • Early asthma control and maintenance with eformoterol following reduction of inhaled corticosteroid dose
    • D. Price D. Dutchman A. Mawson B. Bodalia S. Duggan P. Todd Early asthma control and maintenance with eformoterol following reduction of inhaled corticosteroid dose Thorax 57 2002 791-798
    • (2002) Thorax , vol.57 , pp. 791-798
    • Price, D.1    Dutchman, D.2    Mawson, A.3    Bodalia, B.4    Duggan, S.5    Todd, P.6
  • 44
    • 11144320822 scopus 로고    scopus 로고
    • Initiation of maintenance treatment of persistent asthma: Salmeterol/ fluticasone propionate combination treatment is more effective than inhaled steroid alone
    • A.M. Strand A. Luckow Initiation of maintenance treatment of persistent asthma: Salmeterol/fluticasone propionate combination treatment is more effective than inhaled steroid alone Respir Med 98 2004 1008-1015
    • (2004) Respir. Med. , vol.98 , pp. 1008-1015
    • Strand, A.M.1    Luckow, A.2
  • 45
    • 0028264310 scopus 로고
    • Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid
    • Allen & Hanburys Limited UK Study Group
    • A.P. Greening P.W. Ind M. Northfield G. Shaw Added salmeterol versus higher-dose corticosteroid in asthma patients with symptoms on existing inhaled corticosteroid. Allen & Hanburys Limited UK Study Group Lancet 344 1994 219-224
    • (1994) Lancet , vol.344 , pp. 219-224
    • Greening, A.P.1    Ind, P.W.2    Northfield, M.3    Shaw, G.4
  • 46
    • 0029880013 scopus 로고    scopus 로고
    • Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids
    • A. Woolcock B. Lundback N. Ringdal L.A. Jacques Comparison of addition of salmeterol to inhaled steroids with doubling of the dose of inhaled steroids Am J Respir Crit Care Med 153 1996 1481-1488
    • (1996) Am. J. Respir. Crit. Care Med. , vol.153 , pp. 1481-1488
    • Woolcock, A.1    Lundback, B.2    Ringdal, N.3    Jacques, L.A.4
  • 47
    • 1842370350 scopus 로고    scopus 로고
    • Effect of inhaled formoterol and budesonide on exacerbations of asthma
    • Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group
    • R.A. Pauwels C.G. Lofdahl D.S. Postma et al. Effect of inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids Establishing Therapy (FACET) International Study Group N Engl J Med 337 1997 1405-1411
    • (1997) N. Engl. J. Med. , vol.337 , pp. 1405-1411
    • Pauwels, R.A.1    Lofdahl, C.G.2    Postma, D.S.3
  • 48
    • 0037180086 scopus 로고    scopus 로고
    • Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling
    • M. Roth P.R. Johnson J.J. Rudiger et al. Interaction between glucocorticoids and beta2 agonists on bronchial airway smooth muscle cells through synchronised cellular signalling Lancet 360 2002 1293-1299
    • (2002) Lancet , vol.360 , pp. 1293-1299
    • Roth, M.1    Johnson, P.R.2    Rudiger, J.J.3
  • 49
    • 0033534727 scopus 로고    scopus 로고
    • Ligand-independent activation of the glucocorticoid receptor by beta2-adrenergic receptor agonists in primary human lung fibroblasts and vascular smooth muscle cells
    • O. Eickelberg M. Roth R. Lorx et al. Ligand-independent activation of the glucocorticoid receptor by beta2-adrenergic receptor agonists in primary human lung fibroblasts and vascular smooth muscle cells J Biol Chem 274 1999 1005-1010
    • (1999) J. Biol. Chem. , vol.274 , pp. 1005-1010
    • Eickelberg, O.1    Roth, M.2    Lorx, R.3
  • 50
    • 0035402361 scopus 로고    scopus 로고
    • Effect of a long-acting beta2-agonist over three months on airway wall vascular remodeling in asthma
    • B.E. Orsida C. Ward X. Li et al. Effect of a long-acting beta2-agonist over three months on airway wall vascular remodeling in asthma Am J Respir Crit Care Med 164 2001 117-121
    • (2001) Am. J. Respir. Crit. Care Med. , vol.164 , pp. 117-121
    • Orsida, B.E.1    Ward, C.2    Li, X.3
  • 51
    • 0036911974 scopus 로고    scopus 로고
    • Molecular interactions between glucocorticoids and long-acting beta2-agonists
    • I.M. Adcock K. Maneechotesuwan O. Usmani Molecular interactions between glucocorticoids and long-acting beta2-agonists J Allergy Clin Immunol 110 2002 S261-S268
    • (2002) J. Allergy Clin. Immunol. , vol.110
    • Adcock, I.M.1    Maneechotesuwan, K.2    Usmani, O.3
  • 52
    • 0036191962 scopus 로고    scopus 로고
    • Glucocorticoids reverse IL-1beta-induced impairment of beta-adrenoceptor-mediated relaxation and up-regulation of G-protein-coupled receptor kinases
    • J.C. Mak T. Hisada M. Salmon P.J. Barnes K.F. Chung Glucocorticoids reverse IL-1beta-induced impairment of beta-adrenoceptor-mediated relaxation and up-regulation of G-protein-coupled receptor kinases Br J Pharmacol 135 2002 987-996
    • (2002) Br. J. Pharmacol. , vol.135 , pp. 987-996
    • Mak, J.C.1    Hisada, T.2    Salmon, M.3    Barnes, P.J.4    Chung, K.F.5
  • 53
    • 0025284206 scopus 로고
    • Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge
    • S.E. Wenzel G.L. Larsen K. Johnston N.F. Voelkel J.Y. Westcott Elevated levels of leukotriene C4 in bronchoalveolar lavage fluid from atopic asthmatics after endobronchial allergen challenge Am Rev Respir Dis 142 1990 112-119
    • (1990) Am. Rev. Respir. Dis. , vol.142 , pp. 112-119
    • Wenzel, S.E.1    Larsen, G.L.2    Johnston, K.3    Voelkel, N.F.4    Westcott, J.Y.5
  • 57
    • 0027173832 scopus 로고
    • Differential effects of fluticasone propionate on allergen-evoked bronchoconstriction and increased urinary leukotriene E4 excretion
    • K.M. O'Shaughnessy R. Wellings B. Gillies R.W. Fuller Differential effects of fluticasone propionate on allergen-evoked bronchoconstriction and increased urinary leukotriene E4 excretion Am Rev Respir Dis 147 1993 1472-1476
    • (1993) Am. Rev. Respir. Dis. , vol.147 , pp. 1472-1476
    • O'Shaughnessy, K.M.1    Wellings, R.2    Gillies, B.3    Fuller, R.W.4
  • 58
    • 0036308418 scopus 로고    scopus 로고
    • Bronchoprotective Effects of Leukotriene Receptor Antagonists in Asthma: A Meta-analysis
    • G.P. Currie B.J. Lipworth Bronchoprotective Effects of Leukotriene Receptor Antagonists in Asthma: A Meta-analysis Chest 122 2002 146-150
    • (2002) Chest , vol.122 , pp. 146-150
    • Currie, G.P.1    Lipworth, B.J.2
  • 59
    • 0034821077 scopus 로고    scopus 로고
    • Salmeterol powder provides significantly better benefit than montelukast in asthmatic patients receiving concomitant inhaled corticosteroid therapy
    • J.E. Fish E. Israel J.J. Murray et al. Salmeterol powder provides significantly better benefit than montelukast in asthmatic patients receiving concomitant inhaled corticosteroid therapy Chest 120 2001 423-430
    • (2001) Chest , vol.120 , pp. 423-430
    • Fish, J.E.1    Israel, E.2    Murray, J.J.3
  • 60
    • 0035812019 scopus 로고    scopus 로고
    • Comparison of inhaled salmeterol and oral zafirlukast in asthmatic patients using concomitant inhaled corticosteroids
    • H.S. Nelson R.A. Nathan C. Kalberg S.W. Yancey K.A. Rickard Comparison of inhaled salmeterol and oral zafirlukast in asthmatic patients using concomitant inhaled corticosteroids Med Gen Med 3 2001 3
    • (2001) Med. Gen. Med. , vol.3 , pp. 3
    • Nelson, H.S.1    Nathan, R.A.2    Kalberg, C.3    Yancey, S.W.4    Rickard, K.A.5
  • 61
    • 0142074290 scopus 로고    scopus 로고
    • Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: One year, double blind, randomised, comparative trial
    • L. Bjermer H. Bisgaard J. Bousquet et al. Montelukast and fluticasone compared with salmeterol and fluticasone in protecting against asthma exacerbation in adults: One year, double blind, randomised, comparative trial BMJ 327 2003 891
    • (2003) BMJ , vol.327 , pp. 891
    • Bjermer, L.1    Bisgaard, H.2    Bousquet, J.3
  • 62
    • 0038240597 scopus 로고    scopus 로고
    • Effects of fluticasone plus salmeterol versus twice the dose of fluticasone in asthmatic patients
    • G.P. Currie C.E. Bates D.K. Lee C.M. Jackson B.J. Lipworth Effects of fluticasone plus salmeterol versus twice the dose of fluticasone in asthmatic patients Eur J Clin Pharmacol 59 2003 11-15
    • (2003) Eur. J. Clin. Pharmacol. , vol.59 , pp. 11-15
    • Currie, G.P.1    Bates, C.E.2    Lee, D.K.3    Jackson, C.M.4    Lipworth, B.J.5
  • 63
    • 0038555464 scopus 로고    scopus 로고
    • Effects of montelukast on surrogate inflammatory markers in corticosteroid-treated patients with asthma
    • G.P. Currie D.K. Lee K. Haggart C.E. Bates B.J. Lipworth Effects of montelukast on surrogate inflammatory markers in corticosteroid-treated patients with asthma Am J Respir Crit Care Med 167 2003 1232-1238
    • (2003) Am. J. Respir. Crit. Care Med. , vol.167 , pp. 1232-1238
    • Currie, G.P.1    Lee, D.K.2    Haggart, K.3    Bates, C.E.4    Lipworth, B.J.5
  • 64
    • 3242808287 scopus 로고    scopus 로고
    • Addition of montelukast or salmeterol to fluticasone for protection against asthma attacks: A randomized, double-blind, multicenter study
    • J. Ilowite R. Webb B. Friedman et al. Addition of montelukast or salmeterol to fluticasone for protection against asthma attacks: A randomized, double-blind, multicenter study Ann Allergy Asthma Immunol 92 2004 641-648
    • (2004) Ann. Allergy Asthma Immunol. , vol.92 , pp. 641-648
    • Ilowite, J.1    Webb, R.2    Friedman, B.3
  • 65
    • 0028208940 scopus 로고
    • Persistence of airway obstruction and hyperresponsiveness in subjects with asthma remission
    • L.P. Boulet H. Turcotte A. Brochu Persistence of airway obstruction and hyperresponsiveness in subjects with asthma remission Chest 105 1994 1024-1031
    • (1994) Chest , vol.105 , pp. 1024-1031
    • Boulet, L.P.1    Turcotte, H.2    Brochu, A.3
  • 67
    • 0031881261 scopus 로고    scopus 로고
    • The efficacy and safety of salmeterol compared to theophylline: Meta-analysis of nine controlled studies
    • B. Davies G. Brooks M. Devoy The efficacy and safety of salmeterol compared to theophylline: Meta-analysis of nine controlled studies Respir Med 92 1998 256-263
    • (1998) Respir. Med. , vol.92 , pp. 256-263
    • Davies, B.1    Brooks, G.2    Devoy, M.3
  • 68
    • 0036216744 scopus 로고    scopus 로고
    • Airway inflammation, basement membrane thickening and bronchial hyperresponsiveness in asthma
    • C. Ward M. Pais R. Bish et al. Airway inflammation, basement membrane thickening and bronchial hyperresponsiveness in asthma Thorax 57 2002 309-316
    • (2002) Thorax , vol.57 , pp. 309-316
    • Ward, C.1    Pais, M.2    Bish, R.3
  • 69
    • 0033893557 scopus 로고    scopus 로고
    • Optimal asthma control, starting with high doses of inhaled budesonide
    • H.K. Reddel C.R. Jenkins G.B. Marks et al. Optimal asthma control, starting with high doses of inhaled budesonide Eur Respir J 16 2000 226-235
    • (2000) Eur. Respir. J , vol.16 , pp. 226-235
    • Reddel, H.K.1    Jenkins, C.R.2    Marks, G.B.3
  • 70
    • 0037202790 scopus 로고    scopus 로고
    • Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial
    • R.H. Green C.E. Brightling S. McKenna et al. Asthma exacerbations and sputum eosinophil counts: A randomised controlled trial Lancet 360 2002 1715-1721
    • (2002) Lancet , vol.360 , pp. 1715-1721
    • Green, R.H.1    Brightling, C.E.2    McKenna, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.