Assessment of bioaccumulation and neurotoxicity in rats with portacaval anastomosis and exposed to manganese phosphate: A pilot study

Inhalation Toxicology

Volumn 13, Issue 12, 2001, Pages 1151-1163

  Salehi, F ^a   Carrier, G ^a   Normandin, L ^a   Kennedy, G ^a   Butterworth, R F ^a   Hazell, A ^a   Therrien, G ^a   Mergler, D ^a   Philippe, S ^a   Zayed, J ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

GASOLINE; MANGANESE DERIVATIVE; MANGANESE PHOSPHATE; PHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOACCUMULATION; CAUDATE NUCLEUS; CHEMICAL ANALYSIS; CHRONIC LIVER DISEASE; CIRCADIAN RHYTHM; CONTROLLED STUDY; GLOBUS PALLIDUS; INHALATION; LIVER CIRRHOSIS; LOCOMOTION; NERVE CELL LESION; NEUROTOXICITY; NEUTRON ACTIVATION ANALYSIS; NONHUMAN; PORTOCAVAL SHUNT; PRIORITY JOURNAL; PUTAMEN; RAT;

ADMINISTRATION, INHALATION; ANIMALS; BRAIN; CIRCADIAN RHYTHM; MALE; MANGANESE; MOTOR ACTIVITY; NEURONS; NEUROTOXICITY SYNDROMES; ORGANOMETALLIC COMPOUNDS; PARTICLE SIZE; PILOT PROJECTS; PORTACAVAL SHUNT, SURGICAL; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; VERTEBRATA;

EID: 18244370310     PISSN: 08958378     EISSN: None     Source Type: Journal    
DOI: 10.1080/08958370152647654     Document Type: Article

References (35)

1. +3
2. Emission rates and physicochemical characteristics of Mn particles emitted by vehicles using MMT as octane improver
3. Chronic manganese intake induces changes in the motor activity of rats
4. Portal-systemic encephalopathy: A disorder of multiple neurotransmitter systems
5. Manganese toxicity, dopaminergic dysfunction and hepatic and encephalopathy
6. The physiopathologic significance of manganese in brain: Its relation to schizophrenia and neurodegenerative disorders
7. Effect of long-term administration of Manganese on biogenic amine levels in discrete striatal region of rat brain
8. Animo acid changes in regions of the CNS in relation to function in experimental portal-systemic encephalopathy
9. Increased densities of binding sites for the peripheral-type benzodiazepine receptor ligan [3H]OJ11195 in rat brain following portacaval anastomosis
10. Manganese taken up into the CNS via the olfactory pathway in rats affects astrocytes
11. Central nervous system toxicity. I. Inhibition of spontaneous motor activity in rats after intrathecal administration of manganese chloride
12. Behavioral effects in rats following intrastriatal microinjection of manganese
13. Manganese neurotoxicity in industrial exposure; Proof of effects, critical exposure level, and sensitive test
14. Environmental effects and exposure to manganese from use of methylcyclopentadienyl manganese tricarbonyl (MMT) in gasoline
15. Behavioral effects of chronic manganese administration in rats: Locomotor activity studies
16. Manganese neurotoxicity: A review of clinical features, imaging and pathology
17. Increased manganese concentrations in pallidum of cirrhotic patients
18. Hyperintense globus pallidus on T1-weighted MRI in cirrhotic patients is associated with severity of liver failure
19. Dopamine D1 receptor facilitates GABAA synaptic currents in the rat substancia nigra pars reticulata
20. Quantitative speciation of Mn-bearing particulates emitted from autos burning (methylcyclopentadienyl) manganese tricarbonyl-added gasolines using XANES spectroscopy
21. Effects of oral exposure to mining waste on in vivo dopamine release from rat striatum
22. Manganese deposition in basal ganglia structures results from both portal-systemic shunting and liver dysfunction
23. Manganese-induced hydroxyl radical formation in rat striatum is not attenuated by dopamine depletion or iron chelation in vivo
24. Increased blood manganese in cirrhotic patients: Relationship to pallidal magnetic resonance signal hyperintensity and neurological symptoms
25. Cerebrospinal fluid amino asides in relation to neurological status in experimental portal-systemic encephalopathy
26. Early loss of day-night rhythms following portacaval anastomosis in the rat
27. Uptake of manganese and cadmium from the nasal mucous into the central nervous system via olfactory pathways in rat
28. Pharmacokinetics of inhaled manganese phosphate in male Sprague-Dawley rats following subacute (14-day) exposure
29. Occupational and environmental exposure of garage workers and taxi drivers to airborne manganese arising from the use of methylcyclopantadineyl manganese tricarbonyl in unleaded gasoline
30. Environmental contamination and human exposure to manganese-Contribution of methylcyclopentadienyl manganese tricarbonyl (MMT) in unleaded gasoline
31. Characterization of manganese-containing particles collected from the exhaust emissions of automobiles running with MMT additive
32. Manganese inhibits mitochondrial aconitase: A mechanism of manganese neurotoxicity