Synthesis and study of new 4-quinazolinone inhibitors of the DNA repairenzyme poly(ADP-ribose) polymerase (PARP)

Arkivoc

Volumn 2003, Issue 5, 2003, Pages 121-131

  Kulcsár, Gyozo ^a   Kálai, Tamás ^a   Osz, Erzsébet ^a   Sár, Cecília P ^a   Jeko, József ^b   Sümegi, Balázs ^a   Hideg, Kálmán ^a  

^a UNIVERSITY OF PÉCS   (Hungary)

^b ICN   (Hungary)

Author keywords

Free radical scavengers; Nitroxides; PARP inhibitors; Quinazolines

Indexed keywords

2 (1 OXYL 2,2,5,5 TETRAMETHYL 2,5 DIHYDRO 1H PYRROL 3 YL)QUINAZOLIN 4(3H) ONE; 2 (1 OXYL 2,2,6,6 TETRAMETHYL 1,2,3,6 TETRAHYDROPYRIDINE 4 YL)QUINAZOLIN 4(3H) ONE; 2 (2,2,6,6 TETRAMETHYL 1,2,3,6 TETRAHYDROPYRIN 4 YL)QUINAZOLIN 4(3H) ONE; 2 [(2 PIPERIDIN 1 YLETHYL)THIO]QUINAZOLIN 4(3H) ONE; 2 [[(2,2,6,6 TETRAMETHYL 1,2,3,6 TETRAHYDROPYRIDIN 4 YL)METHYL]THIO]QUINAZOLIN 4(3H) ONE; 2 [[2 (2,2,6,6 TETRAMETHYLPIPERIDIN 1 YL)ETHYL]THIO]QUINAZOLIN 4(3H) ONE; 2 [[2 (DIMETHYLAMINO)ETHYL]THIO]QUINAZOLIN 4(3H) ONE; 2 [[3 (DIMETHYLAMINO)PROPYL]THIO]QUINAZOLIN 4(3H) ONE; 3 [(1 OXYL 2,2,5,5 TETRAMETHYL 2,5 DIHYDRO 1H PYRROL 3 YL)METHYL] 2 METHYLQUINAZOLIN 4(3H) ONE; 3 [(2,2,5,5 TETRAMETHYL 2,5 DIHYDRO 1H PYRROL 3 YL)METHYL] 2 METHYLQUINAZOLIN 4(3H) ONE; 8 HYDROXY 2 METHYL 4(3H) QUINAZOLINONE; H 2641; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE INHIBITOR; PYRIDINE DERIVATIVE; PYRROLE DERIVATIVE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CELL DEATH; CELL LINE; CELL PROTECTION; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; HUMAN CELL; IN VITRO STUDY; LIVER CELL; LIVER PROTECTION; STRUCTURE ACTIVITY RELATION;

EID: 18144450769     PISSN: 14246376     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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