A gene for primary pulmonary hypertension;Un gène pour l'hypertension artérielle pulmonaire primitive

Revue des Maladies Respiratoires

Volumn 18, Issue 5, 2001, Pages 473-478

  Humbert, M ^a   Soubrier, F ^b   Simonneau, G ^a  

^a HÔPITAL ANTOINE BÉCLÈRE   (France)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA;

EDITORIAL; GENE EXPRESSION; GENE MUTATION; HETEROZYGOSITY; HUMAN; MOLECULAR BIOLOGY; MOLECULAR GENETICS; PROTEIN PHOSPHORYLATION; PULMONARY HYPERTENSION; RENDU OSLER WEBER DISEASE; SIGNAL TRANSDUCTION;

EID: 18144441554     PISSN: 07618425     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Editorial

References (32)

1. Les hypertensions pulmonaires
2. Primary pulmonary hypertension
3. Primary pulmonary hypertension: A national prospective study
4. Risk factors for pulmonary arterial hypertension
5. Treatments for severe pulmonary hypertension
6. Genetic anticipation and abnormal gender ratio at birth in familial primary pulmonary hypertension
7. Localization of the gene for familial primary pulmonary hypertension to chromosome 2q31-32
8. Heterozygous germline mutations in a TGF-β receptor, BMPR2, are the cause of familial primary pulmonary hypertension
9. Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene
10. Sporadic primary pulmonary hypertension is associated with germline mutations of the gene encoding BMPR-II, a receptor member of the TGF-β family
11. BMPR2 haploinsufficiency as the inherited molecular mechanism for primary pulmonary hypertension
12. Microsatellite instability of endothelial cell growth and apoptosis genes within plexiform lesions in primary pulmonary hypertension
13. Bone morphogenetic protein receptor 2 mutations in fenfluramine-induced puhnonary arterial hypertension
14. Hereditary hemorrhagic telangiectasia
15. Hereditary hemorrhagic telangiectasia and pulmonary arteriovenous malformations: Issues in clinical management and review of pathogenic mechanisms
16. Controlling TGF-β signaling
17. Pulmonary arteriovenous malformations
18. Pulmonary hypertension in patients with pulmonary arteriovenous fistulae
19. Familial pulmonary hypertension and multiple abnormalities of large systemic arteries in Osler's disease
20. Clinical and molecular genetic features of pulmonary hypertension in hereditary hemorrhagic telangiectasia
21. Biphasic effect of transforming growth factor-beta 1 on in vitro angiogenesis
22. Basic fibroblast growth factor and transforming growth factor beta-1: Synergistic mediators of angiogenesis in vitro
23. Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily
24. Distribution of endoglin in early human development reveals high levels on endocardial cushion tissue mesenchyme during valve formation
25. Role of endoglin in cellular responses to transforming growth factor-beta. A comparative study with betaglycan
26. CD105 antagonizes the inhibitory signaling of transforming growth factor beta1 on human vascular endothelial cells
27. Expression analysis of four endoglin missense mutations suggests that haploinsufficiency is the predominant mechanism for hereditary hemorrhagic telangiectasia type 1
28. Defective angiogenesis in mice lacking endoglin
29. A murine model of hereditary hemorrhagic telangiectasia
30. Defective haematopoiesis and vasculogenesis in transforming growth factor-beta 1 knock out mice
31. BMP type II receptor is required for gastrulation and early development of mouse embryos
32. Primary pulmonary hypertension: A vascular biology and translational research « Work in progress »