New assumptions about oxidative processes involved in steroid hormone biosynthesis: Is the role of cytochrome P-450-activated dioxygen limited to hydroxylation reactions or are dioxygen insertion reactions also possible?

Journal of Steroid Biochemistry and Molecular Biology

Volumn 94, Issue 5, 2005, Pages 405-420

  Lieberman, Seymour ^a   Ma, Shuren ^a   He, Yan ^b  

^a ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^b CITY UNIVERSITY OF NEW YORK   (United States)

Author keywords

Aldosterone; Cortisol; Cyclic peroxides; Cytochrome P 450 activated dioxygen; Estradiol; Hydroxylation; Peroxides; Steroidogenesis

Indexed keywords

11BETA,19 DIHYDROXYDEOXYCORTICOSTERONE; 18 HYDROXYESTRONE; 18 HYDROXYHYDROCORTISONE; 19 HYDROXYDEOXYCORTICOSTERONE; ALDOSTERONE; CARBON; CORTICOSTERONE; CORTICOSTERONE DERIVATIVE; CYTOCHROME P450; DIOXANE; ESTROGEN; ESTRONE DERIVATIVE; HYDROCORTISONE; HYDROPEROXIDE; OXYGEN; PREGNANE DERIVATIVE; STEROID; UNCLASSIFIED DRUG;

AROMATIZATION; CATALYSIS; CATALYST; CHEMICAL BOND; COMPUTER PROGRAM; ESTROGEN SYNTHESIS; HUMAN; HYDROXYLATION; MOLECULAR MECHANICS; MOLECULAR MODEL; NONHUMAN; OXIDATION; REVIEW; STEREOCHEMISTRY; STEROIDOGENESIS; STOICHIOMETRY;

EID: 18144407254     PISSN: 09600760     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jsbmb.2004.12.040     Document Type: Article

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