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6
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For recent examples, see: (d) A. Roy, S. Nandi, H. Ila, and H. Junjappa Org. Lett. 3 2001 229 232
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8
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85030800131
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note
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The yield of this oxidative product is variable run by run. For example, a less strictly degassed DMF led to an decreased yield of the desired annulation product with more production of oxidative by-product in a relatively small scale reaction.
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9
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0000967641
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For a review, see: F.D. Popp Heterocycles 1 1973 165 180
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Popp, F.D.1
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For a recent example, see: M. Takamura, K. Funabashi, M. Kanai, and M. Shibasaki J. Am. Chem. Soc. 123 2001 6801 6908 and Ref. 4 therein cited
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11
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0000454533
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For a review on Ring Annulations via Reissert Compounds, see: F.D. Popp, and B.C. Uff Heterocycles 23 1985 731 740
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Uff, B.C.2
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15
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84986535337
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Cf.: J.T. Hahn, J. Kant, F.D. Popp, S.R. Chhabra, and B.C. Uff J. Heterocycl. Chem. 1992 1165 1176
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16
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85030800896
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note
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For example, the reaction in THF is slow and sluggish.
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19
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2142758219
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T. Itoh, K. Nagata, M. Yokoya, M. Miyazaki, K. Kameoka, S. Nakamura, and A. Ohsawa Chem. Pharm. Bull. 51 2003 951 955
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S.M. Allin, S.L. James, W.P. Martin, T.A.D. Smith, and M.R.J. Elsegood J. Chem. Soc., Perkin Trans. 1 2001 3029 3036
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For the conversion of the 3,4-dimethoxy grouping into the desired 3,4-methylenedioxy grouping at the later stage of CET synthesis, see: S. Yasuda, T. Yamada, and M. Hanaoka Tetrahedron Lett. 27 1986 2023 2026 Furthermore, it has also been demonstrated in our study that the 3,4-methylenedioxy analog of dihydroisoquinoline 1 is equally effective for this annulation process
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0035815160
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For other related methods, see also: A. Padwa, L.S. Beall, C.K. Eidell, and K.J. Worsencroft J. Org. Chem. 66 2001 2414 2421 and references cited therein
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