A highly efficient synthesis of lamellarins K and L by the Michael addition/ring-closure reaction of benzyldihydroisoquinoline derivatives with ethoxycarbonyl-β-nitrostyrenes

Angewandte Chemie - International Edition

Volumn 43, Issue 7, 2004, Pages 866-868

  Ploypradith, Poonsakdi ^a   Mahidol, Chulabhorn ^a,b   Sahakitpichan, Poolsak ^a   Wongbundit, Siriporn ^a   Ruchirawat, Somsak ^a,b  

^a CHULABHORN RESEARCH INSTITUTE   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Alkaloids; Cyclization; Michael addition; Nitrostyrenes; Total synthesis

Indexed keywords

ADDITION REACTIONS; NITROGEN COMPOUNDS; SYNTHESIS (CHEMICAL); TUMORS;

ALKALOIDS; NONTOXIC INHIBITORS;

ENZYMES;

INTEGRASE INHIBITOR; ISOQUINOLINE DERIVATIVE; LAMELLARIN K; LAMERRALIN L; STYRENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL; CONTROLLED STUDY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LACTONIZATION; MICHAEL ADDITION; RING CLOSING METATHESIS;

EID: 4544263266     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200352043     Document Type: Article

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