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Volumn 20, Issue 1, 2005, Pages 92-98

2,5-Hexanedione induced reduction in protein content and mRNA expression of neurofilament in rat cerebral cortex

Author keywords

2,5 Hexanedione; Cerebral cortex; Immunoblotting; Neurofilament; RT PCR

Indexed keywords

ACETONYLACETONE; MESSENGER RNA; NEUROFILAMENT PROTEIN; NEUROFILAMENT PROTEIN H; NEUROFILAMENT PROTEIN L; NEUROFILAMENT PROTEIN M; PROTEIN SUBUNIT; UNCLASSIFIED DRUG;

EID: 18144395405     PISSN: 13826689     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.etap.2004.11.003     Document Type: Article
Times cited : (7)

References (41)
  • 1
    • 0022497238 scopus 로고
    • Interval between the synthesis and assembly of cytoskeletal proteins in cultured neurons
    • M.M. Black, P. Keyser, and E. Sobel Interval between the synthesis and assembly of cytoskeletal proteins in cultured neurons J. Neurosci. 6 1986 1004 1012
    • (1986) J. Neurosci. , vol.6 , pp. 1004-1012
    • Black, M.M.1    Keyser, P.2    Sobel, E.3
  • 2
    • 0022758234 scopus 로고
    • 2,5-Hexanedione neuropathy is associated with the covalent crosslinking of neurofilament proteins
    • M.J. Carden, V.M. Lee, and W.W. Schlaepfer 2,5-Hexanedione neuropathy is associated with the covalent crosslinking of neurofilament proteins Neurochem. Pathol. 5 1986 25 35
    • (1986) Neurochem. Pathol. , vol.5 , pp. 25-35
    • Carden, M.J.1    Lee, V.M.2    Schlaepfer, W.W.3
  • 5
    • 0020015086 scopus 로고
    • Toxicity and metabolism of the neurotoxic hexacarbons n-hexane, 2-hexanone, and 2,5-hexanedione
    • D. Couri, and M. Milks Toxicity and metabolism of the neurotoxic hexacarbons n-hexane, 2-hexanone, and 2,5-hexanedione Annu. Rev. Pharmacol. Toxicol. 22 1982 145 166
    • (1982) Annu. Rev. Pharmacol. Toxicol. , vol.22 , pp. 145-166
    • Couri, D.1    Milks, M.2
  • 6
    • 0025313040 scopus 로고
    • Lack of evidence for the size principle of selective vulnerability of axons in toxic neuropathies. I. The effects of subcutaneous injections of 2,5-hexanedione on behavior and muscle spindle function
    • T.C. De Rojas, and B.D. Goldstein Lack of evidence for the size principle of selective vulnerability of axons in toxic neuropathies. I. The effects of subcutaneous injections of 2,5-hexanedione on behavior and muscle spindle function Toxicol. Appl. Pharmacol. 104 1990 47 58
    • (1990) Toxicol. Appl. Pharmacol. , vol.104 , pp. 47-58
    • De Rojas, T.C.1    Goldstein, B.D.2
  • 7
    • 0033549486 scopus 로고    scopus 로고
    • Age-related atrophy of motor axons in mice deficient in the mid-sized neurofilament subunit
    • G.A. Elder, V.L. Friedrich Jr., A. Margita, and R.A. Lazzarini Age-related atrophy of motor axons in mice deficient in the mid-sized neurofilament subunit J. Cell Biol. 146 1999 181 192
    • (1999) J. Cell Biol. , vol.146 , pp. 181-192
    • Elder, G.A.1    Friedrich Jr., V.L.2    Margita, A.3    Lazzarini, R.A.4
  • 8
    • 0019995381 scopus 로고
    • Assessment of the effects of acrylamide, methylmercury, and 2,5-hexanedione on motor functions in mice
    • S.G. Gilbert, and J.P. Maurissen Assessment of the effects of acrylamide, methylmercury, and 2,5-hexanedione on motor functions in mice J. Toxicol. Environ. Health 10 1982 31 41
    • (1982) J. Toxicol. Environ. Health , vol.10 , pp. 31-41
    • Gilbert, S.G.1    Maurissen, J.P.2
  • 9
    • 0025012184 scopus 로고
    • Reduced conduction function in central nervous system by 2,5-hexanedione
    • M. Hirata Reduced conduction function in central nervous system by 2,5-hexanedione Neurotoxicol. Teratol. 12 1990 623 626
    • (1990) Neurotoxicol. Teratol. , vol.12 , pp. 623-626
    • Hirata, M.1
  • 10
    • 0021280389 scopus 로고
    • Control of axonal caliber by neurofilament transport
    • P.N. Hoffman, J.W. Griffin, and D.L. Price Control of axonal caliber by neurofilament transport J. Cell Biol. 99 1984 705 714
    • (1984) J. Cell Biol. , vol.99 , pp. 705-714
    • Hoffman, P.N.1    Griffin, J.W.2    Price, D.L.3
  • 12
    • 0026044111 scopus 로고
    • Quantitative and qualitative alterations of neuronal and glial intermediate filaments in rat nervous system after exposure to 2,5-hexanedione
    • J.E. Karlsson, L.E. Rosengren, and K.G. Haglid Quantitative and qualitative alterations of neuronal and glial intermediate filaments in rat nervous system after exposure to 2,5-hexanedione J. Neurochem. 57 1991 1437 1444
    • (1991) J. Neurochem. , vol.57 , pp. 1437-1444
    • Karlsson, J.E.1    Rosengren, L.E.2    Haglid, K.G.3
  • 13
    • 0023789510 scopus 로고
    • Evidence for multiple mechanisms responsible for 2,5-hexanedione-induced neuropathy
    • D.M. Lapadula, E. Suwita, and M.B. Abou-Donia Evidence for multiple mechanisms responsible for 2,5-hexanedione-induced neuropathy Brain Res. 458 1988 123 131
    • (1988) Brain Res. , vol.458 , pp. 123-131
    • Lapadula, D.M.1    Suwita, E.2    Abou-Donia, M.B.3
  • 14
    • 0028063968 scopus 로고
    • Neurofilament function and dysfunction: Involvement in axonal growth and neuronal disease
    • M.K. Lee, and D.W. Cleveland Neurofilament function and dysfunction: involvement in axonal growth and neuronal disease Curr. Opin. Cell Biol. 6 1994 34 40
    • (1994) Curr. Opin. Cell Biol. , vol.6 , pp. 34-40
    • Lee, M.K.1    Cleveland, D.W.2
  • 15
  • 17
    • 2942739141 scopus 로고    scopus 로고
    • 2,5-Hexanedione-induced changes in the monomeric neurofilament protein content of rat spinal cord fractions
    • R.M. LoPachin, D. He, M.L. Reid, and L.A. Opanashuk 2,5-Hexanedione- induced changes in the monomeric neurofilament protein content of rat spinal cord fractions Toxicol. Appl. Pharmacol. 198 2004 61 73
    • (2004) Toxicol. Appl. Pharmacol. , vol.198 , pp. 61-73
    • Lopachin, R.M.1    He, D.2    Reid, M.L.3    Opanashuk, L.A.4
  • 19
    • 0242677820 scopus 로고    scopus 로고
    • Gamma-diketone central neuropathy: Quantitative morphometric analysis of axons in rat spinal cord white matter regions and nerve roots
    • R.M. LoPachin, B.S. Jortner, M.L. Reid, and S. Das Gamma-diketone central neuropathy: quantitative morphometric analysis of axons in rat spinal cord white matter regions and nerve roots Toxicol. Appl. Pharmacol. 193 2003 29 46
    • (2003) Toxicol. Appl. Pharmacol. , vol.193 , pp. 29-46
    • Lopachin, R.M.1    Jortner, B.S.2    Reid, M.L.3    Das, S.4
  • 20
    • 0030959155 scopus 로고    scopus 로고
    • The relevance of axonal swellings and atrophy to gamma-diketone neurotoxicity: A forum position paper
    • R.M. LoPachin, and E.J. Lehning The relevance of axonal swellings and atrophy to gamma-diketone neurotoxicity: a forum position paper Neurotoxicology 18 1997 7 22
    • (1997) Neurotoxicology , vol.18 , pp. 7-22
    • Lopachin, R.M.1    Lehning, E.J.2
  • 23
    • 0036902437 scopus 로고    scopus 로고
    • Evidence of zinc protection against 2,5-hexanedione neurotoxicity: Correlation of neurobehavioral testing with biomarkers of excretion
    • M.L. Mateus, A.P. dos Santos, and M.C. Batoreu Evidence of zinc protection against 2,5-hexanedione neurotoxicity: correlation of neurobehavioral testing with biomarkers of excretion Neurotoxicology 23 2002 747 754
    • (2002) Neurotoxicology , vol.23 , pp. 747-754
    • Mateus, M.L.1    Dos Santos, A.P.2    Batoreu, M.C.3
  • 24
    • 0024499213 scopus 로고
    • Experimental increase of neurofilament transport rate: Decreases in neurofilament number and in axon diameter
    • S. Monaco, L. Autilio-Gambetti, R.J. Lasek, M.J. Katz, and P. Gambetti Experimental increase of neurofilament transport rate: decreases in neurofilament number and in axon diameter Neuropathol. Exp. Neurol. 48 1989 23 32
    • (1989) Neuropathol. Exp. Neurol. , vol.48 , pp. 23-32
    • Monaco, S.1    Autilio-Gambetti, L.2    Lasek, R.J.3    Katz, M.J.4    Gambetti, P.5
  • 26
    • 0025866194 scopus 로고
    • Cytoskeletal changes induced by 2,5-hexanedione on developing human neurons in vitro
    • G. Moretto, S. Monaco, M.G. Passarin, M.D. Benedetti, and N. Rizzuto Cytoskeletal changes induced by 2,5-hexanedione on developing human neurons in vitro Arch. Toxicol. 65 1991 409 413
    • (1991) Arch. Toxicol. , vol.65 , pp. 409-413
    • Moretto, G.1    Monaco, S.2    Passarin, M.G.3    Benedetti, M.D.4    Rizzuto, N.5
  • 27
    • 0029067504 scopus 로고
    • Transcriptional and post-transcriptional mechanisms regulating neurofilament and tubulin gene expression during normal development of the rat brain
    • P.F. Moskowitz, and M.M. Oblinger Transcriptional and post-transcriptional mechanisms regulating neurofilament and tubulin gene expression during normal development of the rat brain Brain Res. Mol. Brain Res. 30 1995 211 222
    • (1995) Brain Res. Mol. Brain Res. , vol.30 , pp. 211-222
    • Moskowitz, P.F.1    Oblinger, M.M.2
  • 28
    • 0027359182 scopus 로고
    • Comparative study of modification and degradation of neurofilament proteins in rats subchronically treated with allyl chloride, acrylamide, or 2,5-hexanedione
    • M. Nagano, H. Yamamoto, K. Harada, E. Miyamoto, and M. Futatsuka Comparative study of modification and degradation of neurofilament proteins in rats subchronically treated with allyl chloride, acrylamide, or 2,5-hexanedione Environ. Res. 63 1993 229 240
    • (1993) Environ. Res. , vol.63 , pp. 229-240
    • Nagano, M.1    Yamamoto, H.2    Harada, K.3    Miyamoto, E.4    Futatsuka, M.5
  • 29
    • 0032192425 scopus 로고    scopus 로고
    • Dynamic behavior and organization of cytoskeletal proteins in neurons: Reconciling old and new findings
    • R.A. Nixon Dynamic behavior and organization of cytoskeletal proteins in neurons: reconciling old and new findings Bioessays 20 1998 798 807
    • (1998) Bioessays , vol.20 , pp. 798-807
    • Nixon, R.A.1
  • 30
    • 0034980550 scopus 로고    scopus 로고
    • γ-Diketone peripheral Neuropathy III. Neurofilament gene expression
    • L.A. Opanashuk, D.K. He, E.J. Lehning, and R.M. Lopachin γ-Diketone peripheral Neuropathy III. Neurofilament gene expression Neurotoxicology 22 2001 215 220
    • (2001) Neurotoxicology , vol.22 , pp. 215-220
    • Opanashuk, L.A.1    He, D.K.2    Lehning, E.J.3    Lopachin, R.M.4
  • 31
    • 0024237394 scopus 로고
    • Dephosphorylation of neurofilament proteins enhances their susceptibility to degradation by calpain
    • H.C. Pant Dephosphorylation of neurofilament proteins enhances their susceptibility to degradation by calpain Biochem. J. 256 1988 665 668
    • (1988) Biochem. J. , vol.256 , pp. 665-668
    • Pant, H.C.1
  • 32
    • 84984578783 scopus 로고
    • Atropine reverses antinociception induced by 2,5-hexanedione in rats
    • M.E. Pereira, J.B. Rocha, and I. Izquierdo Atropine reverses antinociception induced by 2,5-hexanedione in rats Pharmacol. Toxicol. 77 1995 91 94
    • (1995) Pharmacol. Toxicol. , vol.77 , pp. 91-94
    • Pereira, M.E.1    Rocha, J.B.2    Izquierdo, I.3
  • 33
    • 0027379280 scopus 로고
    • Decreased levels of the high molecular weight subunit of neurofilaments and accelerated neurofilament transport during the recovery phase of 2,5-hexanedione exposure
    • S.J. Pyle, V. Amarnath, D.G. Graham, and D.C. Anthony Decreased levels of the high molecular weight subunit of neurofilaments and accelerated neurofilament transport during the recovery phase of 2,5-hexanedione exposure Cell Motil. Cytoskeleton 26 1993 133 143
    • (1993) Cell Motil. Cytoskeleton , vol.26 , pp. 133-143
    • Pyle, S.J.1    Amarnath, V.2    Graham, D.G.3    Anthony, D.C.4
  • 34
    • 0017640521 scopus 로고
    • Neurotoxic properties of certain aliphatic hexacarbons
    • P.S. Spencer, and H.H. Schaumburg Neurotoxic properties of certain aliphatic hexacarbons Proc. R. Soc. Med. 70 1977 37 38
    • (1977) Proc. R. Soc. Med. , vol.70 , pp. 37-38
    • Spencer, P.S.1    Schaumburg, H.H.2
  • 35
    • 0017341966 scopus 로고
    • Ultrastructural studies of the dying-back process. III. The evolution of experimental peripheral giant axonal degeneration
    • P.S. Spencer, and H.H. Schaumburg Ultrastructural studies of the dying-back process. III. The evolution of experimental peripheral giant axonal degeneration J. Neuropathol. Exp. Neurol. 36 1977 276 299
    • (1977) J. Neuropathol. Exp. Neurol. , vol.36 , pp. 276-299
    • Spencer, P.S.1    Schaumburg, H.H.2
  • 36
    • 0025764573 scopus 로고
    • Total number and mean cell volume of neocortical neurons in rats exposed to 2,5-hexanedione with and without acetone
    • P. Strange, A. Moller, O. Ladefoged, H.R. Lam, J.J. Larsen, and P. Arlien-Soborg Total number and mean cell volume of neocortical neurons in rats exposed to 2,5-hexanedione with and without acetone Neurotoxicol. Teratol. 13 1991 401 406
    • (1991) Neurotoxicol. Teratol. , vol.13 , pp. 401-406
    • Strange, P.1    Moller, A.2    Ladefoged, O.3    Lam, H.R.4    Larsen, J.J.5    Arlien-Soborg, P.6
  • 37
    • 0026023073 scopus 로고
    • Phosphorylation-related immunoreactivity and the rate of transport of neurofilaments in chronic 2,5-hexanedione intoxication
    • D.F. Watson, K.P. Fittro, P.N. Hoffman, and J.W. Griffin Phosphorylation-related immunoreactivity and the rate of transport of neurofilaments in chronic 2,5-hexanedione intoxication Brain Res. 539 1991 103 109
    • (1991) Brain Res. , vol.539 , pp. 103-109
    • Watson, D.F.1    Fittro, K.P.2    Hoffman, P.N.3    Griffin, J.W.4
  • 38
    • 0034915016 scopus 로고    scopus 로고
    • Alteration in cytoskeletal protein levels in sciatic nerve on post-treatment of diisopropyl phosphorofluoridate (DFP)-treated hen with phenylmethylsulfonyl fluoride
    • K. Xie, R.P. Gupta, and M.B. Abou-Donia Alteration in cytoskeletal protein levels in sciatic nerve on post-treatment of diisopropyl phosphorofluoridate (DFP)-treated hen with phenylmethylsulfonyl fluoride Neurochem. Res. 26 2001 235 243
    • (2001) Neurochem. Res. , vol.26 , pp. 235-243
    • Xie, K.1    Gupta, R.P.2    Abou-Donia, M.B.3
  • 39
    • 0035164218 scopus 로고    scopus 로고
    • The predominant form in which neurofilament subunits undergo axonal transport varies during axonal initiation, elongation, and maturation
    • J.T. Yabe, W.K. Chan, T.M. Chylinski, S. Lee, A.F. Pimenta, and T.B. Shea The predominant form in which neurofilament subunits undergo axonal transport varies during axonal initiation, elongation, and maturation Cell Motil. Cytoskeleton 48 2001 61 83
    • (2001) Cell Motil. Cytoskeleton , vol.48 , pp. 61-83
    • Yabe, J.T.1    Chan, W.K.2    Chylinski, T.M.3    Lee, S.4    Pimenta, A.F.5    Shea, T.B.6
  • 40
    • 0028287702 scopus 로고
    • Effects of 2,5-hexanedione on rat spinal pyramidal tract
    • Y. Yagi Effects of 2,5-hexanedione on rat spinal pyramidal tract Jpn. J. Ind. Health 36 1994 73 180
    • (1994) Jpn. J. Ind. Health , vol.36 , pp. 73-180
    • Yagi, Y.1
  • 41
    • 4043053686 scopus 로고    scopus 로고
    • Tri-ortho-cresyl phosphate (TOCP) decreases the levels of cytoskeletal proteins in hen sciatic nerve
    • X.L. Zhao, Z.P. Zhu, T.L. Zhang, C.L. Zhang, L.H. Yu, and K.Q. Xie Tri-ortho-cresyl phosphate (TOCP) decreases the levels of cytoskeletal proteins in hen sciatic nerve Toxicol. Lett. 152 2004 139 147
    • (2004) Toxicol. Lett. , vol.152 , pp. 139-147
    • Zhao, X.L.1    Zhu, Z.P.2    Zhang, T.L.3    Zhang, C.L.4    Yu, L.H.5    Xie, K.Q.6


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