Sexual risk, nitrite inhalant use, and lack of circumcision associated with HIV seroconversion in men who have sex with men in the United States

Journal of Acquired Immune Deficiency Syndromes

Volumn 39, Issue 1, 2005, Pages 82-89

  Buchbinder, Susan P ^a,b,i   Vittinghoff, Eric ^b   Heagerty, Patrick J ^c   Celum, Connie L ^c   Seage III, George R ^d   Judson, Franklyn N ^e   McKirnan, David ^f   Mayer, Kenneth H ^g,h   Koblin, Beryl A ^e  

^a AIDS Office San Francisco   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^e Univ of Colorado Hlth Sci Center ^*  (United States)

^f NEW YORK BLOOD CENTER   (United States)

^g FENWAY INSTITUTE   (United States)

^h BROWN UNIVERSITY   (United States)

ⁱ NONE   (United States)

Author keywords

Amyl nitrite; Behavior; Circumcision; HIV infection; Men who have sex with men; Risk; Seroincidence

Indexed keywords

NITRITE;

ADULT; ARTICLE; CIRCUMCISION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; EJACULATION; FOLLOW UP; HOMOSEXUALITY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFECTION RISK; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; MULTIVARIATE ANALYSIS; PRIORITY JOURNAL; RISK FACTOR; SEROPREVALENCE; SEXUAL BEHAVIOR; SEXUAL INTERCOURSE; UNITED STATES; VIRUS TRANSMISSION;

ADMINISTRATION, INHALATION; ADULT; CIRCUMCISION, MALE; EDUCATIONAL STATUS; ETHNIC GROUPS; HIV SEROPOSITIVITY; HOMOSEXUALITY, MALE; HUMANS; MALE; NITRITES; REGRESSION ANALYSIS; RISK FACTORS; RISK-TAKING; SEXUAL BEHAVIOR; UNITED STATES;

EID: 18144365468     PISSN: 15254135     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.qai.0000134740.41585.f4     Document Type: Article

References (65)

1. Quan V, Steketee R, Valleroy L, et al. HIV incidence in the United States 1978-1999. J Acquir Immune Defic Syndr. 2002;31:188-201.
2. Weinstock H, Dale M, Gwinn M, et al. HIV seroincidence among patients at clinics for sexually transmitted diseases in nine cities in the United States. J Acquir Immune Defic Syndr. 2002;29:478-483.
3. Ekstrand ML, Stall RD, Paul JP, et al. Gay men report high rates of unprotected anal sex with partners of unknown or discordant HIV status. AIDS. 1999;13:1525-1533.
4. Centers for Disease Control. Advancing HIV prevention: new strategies for a changing epidemic-United States, 2003. MMWR Morb Mortal Wkly Rep. 2003;52:329-332.
5. Centers for Disease Control. HIV/AIDS among racial/ethnic minority men who have sex with men-United States, 1989-1998. MMWR Morb Mortal Wkly Rep. 2000;49:4-11.
6. Katz MH, Schwarcz SK, Kellogg TA, et al. Impact of highly active antiretroviral treatment on HIV seroincidence among men who have sex with men: San Francisco. Am J Public Health. 2002;92:388-394.
7. Centers for Disease Control. HIV incidence among young men who have sex with men-seven US cities, 1994-2000. MMWR Morb Mortal Wkly Rep. 2001;50:440-444.
8. Dukers NH, Goudsmit J, de Wit JB, et al. Sexual risk behaviour relates to the virological and immunological improvements during highly active antiretroviral therapy in HIV-1 infection. AIDS. 2001;15:369-378.
9. Ostrow DE, Fox KJ, Chmiel JS, et al. Attitudes towards highly active antiretroviral therapy are associated with sexual risk taking among HIV-infected and uninfected homosexual men. AIDS. 2002;16:775-780.
10. Vanable PA, Ostrow DG, McKirnan DJ. Viral load and HIV treatment attitudes as correlates of sexual risk behavior among HIV-positive gay men. J Psychosom Res. 2003;54:263-269.
11. Jaffe HW, Choi K, Thomas PA, et al. National case-control study of Kaposi's sarcoma and Pneumocystis carinii pneumonia in homosexual men: part 1. Epidemiologic results. Ann Intern Med. 1983;99:145-151.
12. Coates RA, Calzavara LM, Read SE, et al. Risk factors for HIV infection in male sexual contacts of men with AIDS or an AIDS-related condition. Am J Epidemiol. 1988;128:729-739.
13. van Griensven GJ, Tielman RA, Goudsmit J, et al. Risk factors and prevalence of HIV antibodies in homosexual men in the Netherlands. Am J Epidemiol. 1987;125:1048-1057.
14. Chmiel JS, Detels R, Kaslow RA, et al. Factors associated with prevalent human immunodeficiency virus (HIV) infection in the Multicenter AIDS Cohort Study. Am J Epidemiol. 1987;126:568-577.
15. Samuel MC, Hessol N, Shiboski S, et al. Factors associated with human immunodeficiency virus seroconversion in homosexual men in 3 San Francisco cohort studies, 1984-1989. J Acquir Immune Defic Syndr Hum Retrovirol. 1993;6:303-312.
16. Ostrow DG, DiFranceisco WJ, Chmiel JS, et al. A case-control study of human immunodeficiency virus type 1 seroconversion and risk-related behaviors in the Chicago MACS/CCS Cohort, 1984-1992. Multicenter AIDS Cohort Study. Coping and Change Study. Am J Epidemiol. 1995; 142:875-883.
17. Seage GRR, Mayer KH, Horsburgh CRJ, et al. The relation between nitrite inhalants, unprotected receptive anal intercourse, and the risk of human immunodeficiency virus infection. Am J Epidemiol. 1992;135:1-11.
18. Schechter MT, Boyko WJ, Douglas B, et al. The Vancouver Lymph-adenopathy-AIDS Study: 6. HIV seroconversion in a cohort of homosexual men. CMAJ. 1986;135:1355-1360.
19. Kingsley LA, Rinaldo CRJ, Lyter DW, et al. Sexual transmission efficiency of hepatitis B virus and human immunodeficiency virus among homosexual men. JAMA. 1990;264:230-234.
20. Buchbinder SP, Douglas JMJ, McKirnan DJ, et al. Feasibility of human immunodeficiency virus vaccine trials in homosexual men in the United States: risk behavior, seroincidence, and willingness to participate. J Infect Dis. 1996;174:954-961.
21. Koblin BA, Taylor PE, Avrett S, et al. The feasibility of HIV-1 vaccine efficacy trials among gay/bisexual men in New York City: Project ACHIEVE. AIDS Community Health Initiative Enroute to the Vaccine Effort. AIDS. 1996;10:1555-1561.
22. Seage GR III, Holte SE, Metzger D, et al. Are US populations appropriate for trials of human immunodeficiency virus vaccine? The HIVNET Vaccine Preparedness Study. Am J Epidemiol. 2001;153:619-627.
23. Kooperberg C, Petitti DB. Using logistic regression to estimate the adjusted attributable risk of low birthweight in an unmatched case-control study. Epidemiology. 1991;2:363-366.
24. Vittinghoff E, Douglas J, Judson F, et al. Per-contact risk of human immunodeficiency virus transmission between male sexual partners. Am J Epidemiol. 1999;150:306-311.
25. Garnett GP, Anderson RM. Strategies for limiting the spread of HIV in developing countries: conclusions based on studies of the transmission dynamics of the virus. J Acquir Immune Defic Syndr Hum Retrovirol. 1995;9:500-513.
26. Kremer M, Morcom C. The effect of changing sexual activity on HIV prevalence. Math Biosci. 1998;151:99-122.
27. Anderson RM, Gupta S, Ng W. The significance of sexual partner contact networks for the transmission dynamics of HIV. J Acquir Immune Defic Syndr Hum Retrovirol. 1990;3:417-429.
28. Fleming P, Byers RH, Sweeny PA, et al. HIV prevalence in the United States, 2000 [abstract]. Presented at the 9th Conference on Retroviruses and Opportunistic Infections, Seattle, 2002.
29. MacKellar D, Valleroy LA, Secura GM, et al. Unrecognized HIV infection, risk behaviors, and misperceptions of risk among young men who have sex with men-6 United States Cities, 1994-2000 [abstract]. Presented at the XIV International AIDS Conference, Barcelona, 2002.
30. Ciccarone DH, Kanouse DE, Collins RL, et al. Sex without disclosure of positive HIV serostatus in a US probability sample of persons receiving medical care for HIV infection. Am J Public Health. 2003;93:949-954.
31. Woody GE, Donnell D, Seage GR, et al. Non-injection substance use correlates with risky sex among men having sex with men: data from HIV-NET. Drug Alcohol Depend. 1999;53:197-205.
32. Ostrow DG, Beltran ED, Joseph JG, et al. Recreational drugs and sexual behavior in the Chicago MACS/CCS cohort of homosexually active men. Chicago Multicenter AIDS Cohort Study (MACS)/Coping and Change Study. J Subst Abuse. 1993;5:311-325.
33. Purcell DW, Parsons JT, Halkitis PN, et al. Substance use and sexual transmission risk behavior of HIV-positive men who have sex with men. J Subst Abuse. 2001;13:185-200.
34. Koblin BA, Chesney MA, Husnik MJ, et al. High-risk behaviors among men who have sex with men in 6 US cities: baseline data from the EXPLORE Study. Am J Public Health. 2003;93:926-932.
35. Chesney MA, Barrett DC, Stall R. Histories of substance use and risk behavior: precursors to HIV seroconversion in homosexual men. Am J Public Health. 1998;88:113-116.
36. Casper C, Wald A, Pauk J, et al. Correlates of prevalent and incident Kaposi's sarcoma-associated herpesvirus infection in men who have sex with men. J Infect Dis. 2002;185:990-993.
37. Everett GM. In: Gessa GL, ed. Sexual Behavior: Pharmacology and Biochemistry. New York: Raven Press; 1975:97.
38. Soderberg LS. Immunomodulation by nitrite inhalants may predispose abusers to AIDS and Kaposi's sarcoma. J Neuroimmunol. 1998;83:157-161.
39. Dax EM, Adler WH, Nagel JE, et al. Amyl nitrite alters human in vitro immune function. Immunopharmacol Immunotoxicol. 1991;13:577-587.
40. Stall R, Paul JP, Greenwood G, et al. Alcohol use, drug use and alcohol-related problems among men who have sex with men: the Urban Men's Health Study. Addiction. 2001;96:1589-1601.
41. Richters J, Gerofi J, Donovan B. Why do condoms break or slip off in use? An exploratory study. Int J STD AIDS. 1995;6:11-18.
42. Torian LV, Makki HA, Menzies IB, et al. HIV infection in men who have sex with men, New York City Department of Health sexually transmitted disease clinics, 1990-1999: a decade of serosurveillance finds that racial disparities and associations between HIV and gonorrhea persist. Sex Transm Dis. 2002;29:73-78.
43. Koblin BA, Torian LV, Guilin V, et al. High prevalence of HIV infection among young men who have sex with men in New York City. AIDS. 2000;14:1793-1800.
44. Valleroy LA, MacKellar DA, Karon JM, et al. HIV prevalence and associated risks in young men who have sex with men. Young Men's Survey Study Group. JAMA. 2000;284:198-204.
45. Schwarcz SK, Kellogg TA, McFarland W, et al. Characterization of sexually transmitted disease clinic patients with recent human immunodeficiency virus infection. J Infect Dis. 2002;186:1019-1022.
46. Weiss HA, Quigley MA, Hayes RJ. Male circumcision and risk of HIV infection in sub-Saharan Africa: a systematic review and meta-analysis. AIDS. 2000;14:2361-2370.
47. O'Farrell N, Egger M. Circumcision in men and the prevention of HIV infection: a "meta-analysis" revisited. Int J STD AIDS. 1999;10: 8-16.
48. Grulich AE, Hendry O, Clark E, et al. Circumcision and male-to-male sexual transmission of HIV AIDS. 2001;15:1188-1189.
49. Kreiss JK, Hopkins SG. The association between circumcision status and human immunodeficiency virus infection among homosexual men. J Infect Dis. 1993;168:1404-1408.
50. Patterson BK, Landay A, Siegel JN, et al. Susceptibility to human immunodeficiency virus-1 infection of human foreskin and cervical tissue grown in explant culture. Am J Pathol. 2002;161:867-873.
51. Moses S, Bailey RC, Ronald AR. Male circumcision: assessment of health benefits and risks. Sex Transm Infect. 1998;74:368-373.
52. Renzi C, Douglas JM, Jr, Foster M, et al. Herpes simplex virus type 2 infection as a risk factor for human immunodeficiency virus acquisition in men who have sex with men. J Infect Dis. 2003;187:19-25.
53. Gray RH, Kiwanuka N, Quinn TC, et al. Male circumcision and HIV acquisition and transmission: cohort studies in Rakai, Uganda. Rakai Project Team. AIDS. 2000;14:2371-2381.
54. Darrow WW, Echenberg DF, Jaffe HW, et al. Risk factors for human immunodeficiency virus (HIV) infection in homosexual men. Am J Public Health. 1987;77:479-483.
55. Melbye M, Biggar RJ, Ebbesen P, et al. Seroepidemiology of HTLV-III antibody in Danish homosexual men: prevalence, transmission, and disease outcome. BMJ. 1984;289:573-575.
56. Stone E, Heagerty P, Vittinghoff E, et al. Correlates of condom failure in a sexually active cohort of men who have sex with men. J Acquir Immune Defic Syndr. 1999;20:495-501.
57. Lifson AR, O'Malley PM, Hessol NA, et al. HIV seroconversion in two homosexual men after receptive oral intercourse with ejaculation: implications for counseling concerning safe sexual practices. Am J Public Health. 1990;80:1509-1511.
58. Lane HC, Holmberg SD, Jaffe HW. HIV seroconversion and oral intercourse. Am J Public Health. 1991;81:658.
59. Baba TW, Trichel AM, An L, et al. Infection and AIDS in adult macaques after nontraumatic oral exposure to cell-free SIV Science. 1996;272: 1486-1489.
60. Stahl-Hennig C, Steinman RM, Tenner-Racz K, et al. Rapid infection of oral mucosal-associated lymphoid tissue with simian immunodeficiency virus. Science. 1999;285:1261-1265.
61. Schacker T, Collier AC, Hughes J, et al. Clinical and epidemiologic features of primary HIV infection. Ann Intern Med. 1996;125:257-264.
62. Celum C, Buchbinder S, Donnell D, et al. Early human immunodeficiency virus (HIV) infection in the HIV Network for Prevention Trials vaccine preparedness cohort: risk behaviors, symptoms, and early plasma and genital tract virus load. J Infect Dis. 2001;183:23-35.
63. Hecht FM, Busch MP, Rawal B, et al. Use of laboratory tests and clinical symptoms for identification of primary HIV infection. AIDS. 2002;16: 1119-1129.
64. Page-Shafer K, Shiboski CH, Osmond DH, et al. Risk of HIV infection attributable to oral sex among men who have sex with men and in the population of men who have sex with men. AIDS. 2002;16:2350-2352.
65. del Romero J, Marincovich B, Castilla J, et al. Evaluating the risk of HIV transmission through unprotected orogenital sex. AIDS. 2002;16:1296-1297.