Comparative sensitivity of rat cerebellar neurons to dysregulation of divalent cation homeostasis and cytotoxicity caused by methylmercury

Toxicology and Applied Pharmacology

Volumn 208, Issue 3, 2005, Pages 222-232

  Edwards, Joshua R ^a   Marty, M Sue ^a,b   Atchison, William D ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

^b DOW CHEMICAL COMPANY   (United States)

Author keywords

Calcium; Calcium mediated cell death; Cerebellar granule neuron; Divalent cation homeostasis; Fura 2; Intracellular calcium regulation; Methylmercury; Purkinje neuron; TPEN

Indexed keywords

CALCIUM ION; CHELATING AGENT; DIVALENT CATION; FURA 2; METHYLMERCURY;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CATION TRANSPORT; CELL VIABILITY; CEREBELLUM CORTEX; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; FETUS; FLUORESCENCE; GRANULE CELL; IMMUNOHISTOCHEMISTRY; NONHUMAN; PURKINJE CELL; RAT;

AIR POLLUTANTS; ANIMALS; CALCIUM; CATIONS, DIVALENT; CELL CULTURE TECHNIQUES; CELL DEATH; CELL SURVIVAL; CELLS, CULTURED; CEREBELLUM; CHELATING AGENTS; ETHYLENEDIAMINES; FETUS; FURA-2; HOMEOSTASIS; METHYLMERCURY COMPOUNDS; MICROSCOPY, FLUORESCENCE, MULTIPHOTON; N-METHYLASPARTATE; NEURONS; PURKINJE CELLS; RATS;

EID: 18044386289     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2005.02.015     Document Type: Article

References (57)

1. 2+ J. Biol. Chem. 260 1985 2719 2727
2. M. Aschner Astrocyte metallothioneins (MTs) and their neuroprotective role Ann. N. Y. Acad. Sci. 825 1997 334 347
3. M. Aschner, D. Vitarella, J.W. Allen, D.R. Conklin, and K.S. Cowan Methylmercury-induced inhibition of regulatory volume decrease in astrocytes: characterization of osmoregulator efflux and its reversal by amiloride Brain Res. 811 1998 133 142
4. W.D. Atchison, and T. Narahashi Methylmercury-induced depression of neuromuscular transmission in the rat Neurotoxicology 3 1982 37 50
5. W.D. Atchison, U. Joshi, and J.E. Thornburg Irreversible suppression of calcium entry into nerve terminals by methylmercury J. Pharmacol. Exp. Ther. 238 1986 618 624
6. C. Batini, M. Palestini, M. Thomasset, and R. Vigot Cytoplasmic calcium buffer, calbindin D-28k, is regulated by excitatory amino acids NeuroReport 4 1993 927 930
7. M.R. Celio Calbindin d-28k and parvalbumin in the rat nervous system Neuroscience 35 1990 375 475
8. L.W. Chang Neurotoxic effects of mercury-a review Environ. Res. 14 1977 329 373
9. D.W. Choi, and J.Y. Koh Zinc and brain injury Annu. Rev. Neurosci. 21 1998 347 375
10. T.W. Clarkson The pharmacology of mercury compounds Annu. Rev. Pharmacol. 12 1972 375 406
11. 19F-NMR study J. Neurochem. 63 1994 383 386
12. M.F. Denny, and W.D. Atchison Mercurial-induced alterations in neuronal divalent cation homeostasis Neurotoxicology 17 1996 47 61
13. M.F. Denny, M.F. Hare, and W.D. Atchison Methylmercury alters intrasynaptosomal concentrations of endogenous polyvalent cations Toxicol. Appl. Pharmacol. 122 1993 222 232
14. J.M. Dubinsky Examination of the role of calcium in neuronal death Ann. N. Y. Acad. Sci. 679 1993 34 42
15. J. Edwards, and W. Atchison Expression of calbindin D-28k correlates with decreased methylmercury (MeHg) cytotoxicity in myenteric plexus neurons Abstract, Annual Meeting, Society of Toxicology. Salt Lake City, UT 2003
16. J. Edwards, P. Cobbett, and W. Atchison Comparative disruption of intracellular calcium regulation by methylmercury in PC12 and PC18 cells Program No. 833.5. 2002 Abstract Viewer/Itinerary Planner 2002 Society for Neuroscience Washington, DC Online
17. S. Furuya, A. Makino, and Y. Hirabayashi An improved method for culturing cerebellar Purkinje cells with differentiated dendrites under a mixed monolayer setting Brain Res. Brain Res. Protoc. 3 1998 192 198
18. D.L. Gruol Cultured cerebellar neurons: endogenous and exogenous components of Purkinje cell activity and membrane response to putative transmitters Brain Res. 263 1983 223 241
19. D.L. Gruol, and C.P. Crimi Morphological and physiological properties of rat cerebellar neurons in mature and developing cultures Brain Res. 469 1988 135 146
20. 2+ signaling pathways linked to glutamate receptor activation in the somatic and dendritic regions of cultured cerebellar Purkinje neurons J. Neurophysiol. 76 1996 3325 3340
21. 2+ indicators with greatly improved fluorescence properties J. Biol. Chem. 260 1985 3440 3450
22. 2+ on human neuronal N- and R-type high-voltage activated calcium channels transiently expressed in human embryonic kidney 293 cells J. Pharmacol. Exp. Ther. 306 2003 1129 1136
23. i in NG108-15 cells Toxicol. Appl. Pharmacol. 135 1995 299 307
24. 2+ from intracellular stores sensitive to inositol 1,4,5-trisphosphate in NG108-15 cells J. Pharmacol. Exp. Ther. 272 1995 1016 1023
25. 2+ and heavy metals in NG108-15 cells J. Pharmacol. Exp. Ther. 266 1993 1626 1635
26. D. Hunter, and D. Russell Focal cerebral and cerebellar atrophy in a human subject due to organic mercury compounds Neurol. Neurosurg. Psychiatry 17 1954 235 241
27. T. Himi, M. Ikeda, I. Sato, T. Yuasa, and S. Murota Purkinje cells express neuronal nitric oxide synthase after methylmercury administration Brain Res. 718 1996 189 192
28. M. Ito The Cerebellum and Neural Control 1984 Raven Press New York
29. M.S. Juang An electrophysiological study of the action of methylmercuric chloride and mercuric chloride on the sciatic nerve-sartorius muscle preparation of the frog Toxicol. Appl. Pharmacol. 37 1976 339 348
30. 2+ pool in cerebellar Purkinje neurons Biophys. J. 73 1997 3349 3357
31. 2+ by neurotoxic organometals: distinctive mechanisms Toxicol. Appl. Pharmacol. 88 1987 77 86
32. H. Komulainen, and J. Tuomisto Effects of heavy metals on monoamine uptake and release in brain synaptosomes and blood platelets Neurobehav. Toxicol. Teratol. 4 1982 647 649
33. K. Leyshon, and A.J. Morgan An integrated study of the morphological and gross-elemental consequences of methyl mercury intoxication in rats, with particular attention on the cerebellum Scanning Microsc. 3 1991 895 904
34. K. Leyshon-Sorland, B. Jasani, and A.J. Morgan The localization of mercury and metallothionein in the cerebellum of rats experimentally exposed to methylmercury Histochem. J. 26 1994 161 169
35. T.L. Limke, and W.D. Atchison Acute exposure to methylmercury opens the mitochondrial permeability transition pore in rat cerebellar granule cells Toxicol. Appl. Pharmacol. 178 2002 52 61
36. T.L. Limke, J.K. Otero-Montañez, and W.D. Atchison Evidence for interactions between intracellular calcium stores during methylmercury-induced intracellular calcium dysregulation in rat cerebellar granule neurons J. Pharmacol. Exp. Ther. 304 2003 949 958
37. 2+ dysregulation and neuronal death in rat cerebellar granule cells through an M3 muscarinic receptor-linked pathway Toxicol. Sci. 80 2004 60 68
38. T.L. Limke, S.R. Heidemann, and W.D. Atchison Disruption of intraneuronal divalent cation regulation by methylmercury: are specific targets involved in altered neuronal development and cytotoxicity in methylmercury poisoning? Neurotoxicology 25 2004 741 760
39. H. Manev, E. Kharlamov, T. Uz, R.P. Mason, and C.M. Cagnoli Characterization of zinc-induced neuronal death in primary cultures of rat cerebellar granule cells Exp. Neurol. 146 1997 171 178
40. 2+ entry in rat cerebellar granule cells following in vitro exposure to methyl mercury Toxicol. Appl. Pharmacol. 147 1997 319 330
41. 2+ as a probable contributor to decreased viability in cerebellar granule cells following acute exposure to methylmercury Toxicol. Appl. Pharmacol. 150 1998 98 105
42. I.M. Mintz, M.E. Adams, and B.P. Bean P-type calcium channels in rat central and peripheral neurons Neuron 9 1992 85 95
43. F. Mori, K. Tanji, and K. Wakabayashi Widespread calcium deposits, as detected using the alizarin red S technique, in the nervous system of rats treated with dimethyl mercury Neuropathology 20 2000 210 215
44. W.M. Mundy, D. Parran, and S. Barone Jr. Gestational exposure to methylmercury alters neurotrophin- and carbachol-stimulated phosphatidylinositide hydrolysis in cerebral cortex of neonatal rats Neurotox. Res. 1 2000 271 283
45. J.R. O'Kusky, and E.G. McGeer Methylmercury-induced movement and postural disorders in developing rat: high-affinity uptake of choline, glutamate, and gamma-aminobutyric acid in the cerebral cortex and caudate-putamen J. Neurochem. 53 1989 999 1006
46. S.T. Park, K.T. Lim, Y.T. Chung, and S.U. Kim Methylmercury-induced neurotoxicity in cerebral neuron culture is blocked by antioxidants and NMDA receptor antagonists Neurotoxicology 17 1996 37 45
47. D.J. Perkel, S. Hestrin, P. Sah, and R.A. Nicoll Excitatory synaptic currents in Purkinje cells Proc. R. Soc. London, Ser. B Biol. Sci. 241 1990 116 121
48. M.C. Raff, K.L. Fields, S.I. Hakomori, R. Mirsky, R.M. Pruss, and J. Winter Cell-type-specific markers for distinguishing and studying neurons and the major classes of glial cells in culture Brain Res. 174 1979 283 308
49. 2+ channel currents in rat cerebellar granule neurons J. Neurosci. 15 1995 2995 3012
50. 2+ and inositol phosphate levels in cultured cerebellar granule neurons J. Neurochem. 61 1993 648 657
51. J.E. Sirois, and W.D. Atchison Methylmercury affects multiple subtypes of calcium channels in rat cerebellar granule cells Toxicol. Appl. Pharmacol. 167 2000 1 11
52. T.L. Syversen, G. Totland, and P.R. Flood Early morphological changes in rat cerebellum caused by a single dose of methylmercury Arch. Toxicol. 47 1981 101 111
53. C. Watanabe Modification of mercury toxicity by selenium: practical importance? Tohoku J. Exp. Med. 196 2002 71 77
54. P.F. Worley, J.M. Baraban, and S.H. Snyder Inositol 1,4,5-trisphosphate receptor binding: autoradiographic localization in rat brain J. Neurosci. 9 1989 339 346
55. A.J. Yool, R.M. Krieger, and D.L. Gruol Multiple ionic mechanisms are activated by the potent agonist quisqualate in cultured cerebellar Purkinje neurons Brain Res. 573 1992 83 94
56. A receptor-mediated inhibitory synaptic transmission is primarily responsible for its early stimulatory effects on hippocampal CA1 excitatory synaptic transmission J. Pharmacol. Exp. Ther. 282 1997 64 73
57. A receptor-mediated spontaneous IPSCs in Purkinje and granule cells of rat cerebellar slices J. Physiol. (London) 550 2003 191 204