메뉴 건너뛰기




Volumn 65, Issue 1, 2005, Pages 69-76

Development and validation of algorithms for measuring G-protein coupled receptor activation in cells using the LSC-based imaging cytometer platform

Author keywords

Arrestin; G protein coupled receptor; Green fluorescent protein; iCyte; Imaging cytometer; Laser scanning cytometry; Transfluor

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; G PROTEIN COUPLED RECEPTOR; GREEN FLUORESCENT PROTEIN; RETINA S ANTIGEN;

EID: 18044381723     PISSN: 15524922     EISSN: None     Source Type: Journal    
DOI: 10.1002/cyto.a.20128     Document Type: Article
Times cited : (9)

References (21)
  • 1
    • 0035101820 scopus 로고    scopus 로고
    • Evolving concepts in G protein-coupled receptor endocytosis: The role in receptor desensitization and signaling
    • Ferguson SS. Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev 2001;53:1-24.
    • (2001) Pharmacol Rev , vol.53 , pp. 1-24
    • Ferguson, S.S.1
  • 2
    • 0030736417 scopus 로고    scopus 로고
    • A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation
    • Barak LS, Ferguson SS, Zhang J, Caron MG. A beta-arrestin/green fluorescent protein biosensor for detecting G protein-coupled receptor activation. J Biol Chem 1997;272:27497-27500.
    • (1997) J Biol Chem , vol.272 , pp. 27497-27500
    • Barak, L.S.1    Ferguson, S.S.2    Zhang, J.3    Caron, M.G.4
  • 3
    • 0034595860 scopus 로고    scopus 로고
    • Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors
    • Oakley RH, Laporte SA, Holt JA, Caron MG, Barak LS. Differential affinities of visual arrestin, beta arrestin1, and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors. J Biol Chem 2000;275:17201-17210.
    • (2000) J Biol Chem , vol.275 , pp. 17201-17210
    • Oakley, R.H.1    Laporte, S.A.2    Holt, J.A.3    Caron, M.G.4    Barak, L.S.5
  • 4
    • 0036473397 scopus 로고    scopus 로고
    • The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals
    • Luttrell LM, Lefkowitz RJ. The role of beta-arrestins in the termination and transduction of G-protein-coupled receptor signals. J Cell Sci 2002;115:455-465.
    • (2002) J Cell Sci , vol.115 , pp. 455-465
    • Luttrell, L.M.1    Lefkowitz, R.J.2
  • 5
    • 33646664206 scopus 로고    scopus 로고
    • Real time imaging of GPCR-mediated arrestin translocation as a strategy to evaluate receptor-protein interactions
    • George SR, O'Dowd BF, editors. Hoboken, NJ: John Wiley & Sons
    • Oakley RH, Barak LS, Caron MG. Real time imaging of GPCR-mediated arrestin translocation as a strategy to evaluate receptor-protein interactions. In: George SR, O'Dowd BF, editors. G protein coupled receptor-protein interactions. Hoboken, NJ: John Wiley & Sons; 2005. p 53-80.
    • (2005) G Protein Coupled Receptor-Protein Interactions , pp. 53-80
    • Oakley, R.H.1    Barak, L.S.2    Caron, M.G.3
  • 6
    • 33646667433 scopus 로고    scopus 로고
    • Transfluor® provides a universal cell-based assay for screening G protein coupled receptors
    • Minor L, editor. New York: Marcel Dekker. Forthcoming
    • Oakley RH, Cowan CL, Hudson CC, Loomis CR. Transfluor® provides a universal cell-based assay for screening G protein coupled receptors. In: Minor L, editor. Handbook of assay development in drug discovery. New York: Marcel Dekker; 2005. Forthcoming.
    • (2005) Handbook of Assay Development in Drug Discovery
    • Oakley, R.H.1    Cowan, C.L.2    Hudson, C.C.3    Loomis, C.R.4
  • 8
    • 0346554737 scopus 로고    scopus 로고
    • G protein-coupled receptor desensitization as a measure of signaling: Modeling of arrestin recruitment to activated CCK-B receptors
    • Barak LS, Oakley RH, Shetzline MA. G protein-coupled receptor desensitization as a measure of signaling: modeling of arrestin recruitment to activated CCK-B receptors. Assay Drug Dev Technol 2003;1:409-424.
    • (2003) Assay Drug Dev Technol , vol.1 , pp. 409-424
    • Barak, L.S.1    Oakley, R.H.2    Shetzline, M.A.3
  • 9
    • 0012132962 scopus 로고    scopus 로고
    • The cellular distribution of fluorescently labeled arrestins provides an robust, sensitive, and universal assay for screening G protein-coupled receptors
    • Oakley RH, Hudson CC, Cruickshank RD, Meyers DM, Payne RE Jr, Rhem SM, Loomis CR. The cellular distribution of fluorescently labeled arrestins provides an robust, sensitive, and universal assay for screening G protein-coupled receptors. Assay Drug Dev Technol 2002;1:21-30.
    • (2002) Assay Drug Dev Technol , vol.1 , pp. 21-30
    • Oakley, R.H.1    Hudson, C.C.2    Cruickshank, R.D.3    Meyers, D.M.4    Payne Jr., R.E.5    Rhem, S.M.6    Loomis, C.R.7
  • 10
    • 0025778621 scopus 로고
    • Microscope-based multiparameter laser scanning cytometer yielding data comparable to flow cytometry data
    • Kamentsky LA, Kamentsky LD. Microscope-based multiparameter laser scanning cytometer yielding data comparable to flow cytometry data. Cytometry 1991;12:381-387.
    • (1991) Cytometry , vol.12 , pp. 381-387
    • Kamentsky, L.A.1    Kamentsky, L.D.2
  • 11
    • 0035227195 scopus 로고    scopus 로고
    • Laser scanning cytometry
    • Kamentsky LA. Laser scanning cytometry. Methods Cell Biol 2001;63:51-87.
    • (2001) Methods Cell Biol , vol.63 , pp. 51-87
    • Kamentsky, L.A.1
  • 12
    • 0033527663 scopus 로고    scopus 로고
    • Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization
    • Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG. Association of beta-arrestin with G protein-coupled receptors during clathrin-mediated endocytosis dictates the profile of receptor resensitization. J Biol Chem 1999;274:32248-32257.
    • (1999) J Biol Chem , vol.274 , pp. 32248-32257
    • Oakley, R.H.1    Laporte, S.A.2    Holt, J.A.3    Barak, L.S.4    Caron, M.G.5
  • 13
    • 0032728297 scopus 로고    scopus 로고
    • A novel cell permeant and far red-fluorescing DNA probe, Draq5, for blood cell discrimination by flow cytometry
    • Smith PJ, Wiltshire M, Davies S, Patterson LH, Hoy T. A novel cell permeant and far red-fluorescing DNA probe, Draq5, for blood cell discrimination by flow cytometry. J Immunol Methods 1999;229:131-139.
    • (1999) J Immunol Methods , vol.229 , pp. 131-139
    • Smith, P.J.1    Wiltshire, M.2    Davies, S.3    Patterson, L.H.4    Hoy, T.5
  • 14
    • 0033003760 scopus 로고    scopus 로고
    • A simple statistical parameter for use in evaluation and validation of high throughput screening assays
    • Zhang JH, Chung TD, Oldenburg KR. A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J Biomol Screen 1999;4:67-73.
    • (1999) J Biomol Screen , vol.4 , pp. 67-73
    • Zhang, J.H.1    Chung, T.D.2    Oldenburg, K.R.3
  • 15
    • 0345012069 scopus 로고    scopus 로고
    • Clinical applications of laser scanning cytometry
    • Tarnok A, Gerstner AO. Clinical applications of laser scanning cytometry. Cytometry 2002;50:133-143.
    • (2002) Cytometry , vol.50 , pp. 133-143
    • Tarnok, A.1    Gerstner, A.O.2
  • 16
    • 0033808687 scopus 로고    scopus 로고
    • Translocation of Bax to mitochondria during apoptosis measured by laser scanning cytometry
    • Bedner E, Li X, Kunicki J, Darzynkiewicz Z. Translocation of Bax to mitochondria during apoptosis measured by laser scanning cytometry. Cytometry 2000;41:83-88.
    • (2000) Cytometry , vol.41 , pp. 83-88
    • Bedner, E.1    Li, X.2    Kunicki, J.3    Darzynkiewicz, Z.4
  • 17
    • 0035374624 scopus 로고    scopus 로고
    • Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis
    • Oakley RH, Laporte SA, Holt JA, Barak LS, Caron MG. Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis. J Biol Chem 2001;276:19452-19460.
    • (2001) J Biol Chem , vol.276 , pp. 19452-19460
    • Oakley, R.H.1    Laporte, S.A.2    Holt, J.A.3    Barak, L.S.4    Caron, M.G.5
  • 19
    • 0037452623 scopus 로고    scopus 로고
    • Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference
    • Ahn S, Nelson CD, Garrison TR, Miller WE, Lefkowitz RJ. Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference. Proc Natl Acad Sci USA 2003;100:1740-1744.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1740-1744
    • Ahn, S.1    Nelson, C.D.2    Garrison, T.R.3    Miller, W.E.4    Lefkowitz, R.J.5
  • 20
    • 0141483377 scopus 로고    scopus 로고
    • A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis
    • Ge L, Ly Y, Hollenberg M, DeFea K. A beta-arrestin-dependent scaffold is associated with prolonged MAPK activation in pseudopodia during protease-activated receptor-2-induced chemotaxis. J Biol Chem 2003;278:34418-34426.
    • (2003) J Biol Chem , vol.278 , pp. 34418-34426
    • Ge, L.1    Ly, Y.2    Hollenberg, M.3    DeFea, K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.