Small GTPase RhoA is required for ooplasmic segregation and spindle rotation, but not for spindle organization and chromosome separation during mouse oocyte maturation, fertilization, and early cleavage

Molecular Reproduction and Development

Volumn 71, Issue 2, 2005, Pages 256-261

  Zhong, Zhi Sheng ^a   Huo, Li Jun ^a   Liang, Cheng Guang ^a   Chen, Da Yuan ^a   Sun, Qing Yuan ^a  

^a INSTITUTE OF ZOOLOGY   (China)

Author keywords

Fertilization; Meiosis; Microfilament; Mouse; Oocyte; RhoA

Indexed keywords

GUANOSINE TRIPHOSPHATASE; PROTEIN ANTIBODY; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN ANTIBODY; UNCLASSIFIED DRUG;

ANAPHASE; ANIMAL CELL; ARTICLE; CELL POLARITY; CHROMOSOME SEGREGATION; CONTROLLED STUDY; CYTOKINESIS; ENZYME ACTIVITY; ENZYME LOCALIZATION; FEMALE; FERTILIZATION; GERMINAL VESICLE; MALE; MICROFILAMENT; MICROINJECTION; MITOSIS; MITOSIS SPINDLE; NONHUMAN; OOCYTE CLEAVAGE; OOCYTE MATURATION; PRIORITY JOURNAL; PROTEIN FUNCTION; STRESS FIBER; TELOPHASE;

AMIDES; ANIMALS; CELLS, CULTURED; CLEAVAGE STAGE, OVUM; ENZYME INHIBITORS; FEMALE; FERTILIZATION; FERTILIZATION IN VITRO; MALE; MICE; MITOTIC SPINDLE APPARATUS; OOCYTES; OOGENESIS; PYRIDINES; RHOA GTP-BINDING PROTEIN;

EID: 18044376990     PISSN: 1040452X     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrd.20253     Document Type: Article

References (29)

1. Adachi T, Vita R, Sannohe S, Stafford S, Alam R, Kayaba H, Chihara J. 2001. The functional role of rho and rho-associated coiled-coil forming protein kinase in eotaxin signaling of eosinophils. J Immunol 167:4609-4615.
2. Chatot CL, Ziomek CA, Bavister BD, Lewis JL, Torres I. 1989. An improved culture medium supports development of random-bred 1-cell mouse embryos in vitro. J Reprod Fertil 86:679-688.
3. Cheon YP, Kim SW, Kim SJ, Yeom YI, Cheong C, Ha KS. 2000. The role of RhoA in the germinal vesicle breakdown of mouse oocytes. Biochem Biophys Res Commun 273:997-1002.
4. Clayton L, Hall A, Johnson MH. 1999. A role for Rho-like GTPases in the polarisation of mouse eight-cell blastomeres. Dev Biol 205:322-331.
5. Covian-Nares F, Martinez-Cadena G, Lopez-Godinez J, Voronina E, Wessel GM, Garcia-Soto J. 2004. A Rho-signaling pathway mediates cortical granule translocation in the sea urchin oocyte. Mech Dev 121:225-235.
6. Cuellar-Mata P, Martinez-Cadena G, Lopez-Godinez J, Obregon A, Garcia-Soto J. 2000. The GTP-binding protein RhoA localizes to the cortical granules of Strongylocentrotus purpuratas sea urchin egg and is secreted during fertilization. Eur J Cell Biol 79:81-91.
7. Etienne-Manneville S, Hall A. 2002. Rho GTPases in cell biology. Nature 420:629-635.
8. Fan HY, Sun QY. 2004. Involvement of mitogen-activated protein kinase cascade during oocyte maturation and fertilization in mammals. Biol Reprod 70:535-547.
9. Fraser LR, Drury LM. 1975. The relationship between sperm concentration and fertilization in vitro of mouse eggs. Biol Reprod 13:513-518.
10. Frost JA, Xu S, Hutchison MR, Marcus S, Cobb MH. 1996. Actions of Rho family small G proteins and p21-activated protein kinases on mitogen-activated protein kinase family members. Mol Cell Biol 16:3707-3713.
11. Gao S, Gasparrini B, McGarry M, Ferrier T, Fletcher J, Harkness L, De Sousa P, Wilmut I. 2002. Germinal vesicle material is essential for nucleus remodeling after nuclear transfer. Biol Reprod 67:928-9234.
12. Hall A. 1998. Rho GTPases and the actin cytoskeleton. Science 279:509-514.
13. Kusama T, Mukai M, Iwasaki T, Tatsuta M, Matsumoto Y, Akedo H, Nakamura H. 2001. Inhibition of epidermal growth factor-induced RhoA translocation and invasion of human pancreatic cancer cells by 3-hydroxy-3-methylglutaryl-coenzyme a reductase inhibitors. Cancer Res 61:4885-4891.
14. Laboureau J, Dubertret L, Lebreton-De Coster C, Coulomb B. 2004. ERK activation by mechanical strain is regulated by the small G proteins rac-1 and rhoA. Exp Dermatol 13:70-77.
15. Lee JS, Kamijo K, Ohara N, Kitamura T, Miki T. 2004. MgcRacGAP regulates cortical activity through RhoA during cytokinesis. Exp Cell Res 293:275-282.
16. Mabuchi I, Hamaguchi Y, Fujimoto H, Morii N, Mishima M, Narumiya S. 1993. A rho-like protein is involved in the organisation of the contractile ring in dividing sand dollar eggs. Zygote 1:325-331.
17. Maddox AS, Burridge K. 2003. RhoA is required for cortical retraction and rigidity during mitotic cell rounding. J Cell Biol 160:255-265.
18. Maddox AS, Oegema K. 2003. Closing the GAP: A role for a RhoA GAP in cytokinesis. Mol Cell 11:846-848.
19. Manzo S, Martinez-Cadena G, Lopez-Godinez J, Pedraza-Reyes M, Garcia-Soto J. 2003. A Rho GTPase controls the rate of protein synthesis in the sea urchin egg. Biochem Biophys Res Commun 210:685-690.
20. Maro B, Johnson MH, Pickering SJ, Flach G. 1984. Changes in actin distribution during fertilization of the mouse egg. J Embryol Exp Morphol 81:211-237.
21. Massoumi R, Larsson C, Sjolander A. 2002. Leukotriene D(4) induces stress-fibre formation in intestinal epithelial cells via activation of RhoA and PKCdelta. J Cell Sci 115:3509-3515.
22. Nishimura Y, Nakano K, Mabuchi I. 1998. Localization of Rho GTPase in sea urchin eggs. FEBS Lett 441:121-126.
23. Tahara M, Morishige K, Sawada K, Ikebuchi Y, Kawagishi R, Tasaka K, Murata Y. 2002. RhoA/Rho-kinase cascade is involved in oxytocin-induced rat uterine contraction. Endocrinology 143:920-929.
24. Takami M, Preston SL, Behrman HR. 2000. Eicosatetraynoic and eicosatriynoic acids, lipoxygenase inhibitors, block meiosis via antioxidant action. Am J Physiol Cell Physiol 278:C646-C650.
25. Takaishi K, Sasaki T, Kameyama T, Tsukita S, Takai Y. 1995. Translocation of activated Rho from the cytoplasm to membrane ruffling area, cell-cell adhesion sites and cleavage furrows. Oncogene 11:39-48.
26. Yao LJ, Zhong ZS, Zhang LS, Chen DY, Schatten H, Sun QY. 2004. Aurora-A is a critical regulator of microtubule assembly and nuclear activity in mouse oocytes, fertilized eggs, and early embryos. Biol Reprod 70:1392-1399.
27. Yonemura S, Hirao-Minakuchi K, Nishimura Y. 2004. Rho localization in cells and tissues. Exp Cell Res 295:300-314.
28. i transients to ooplasmic segregation involves small GTPase rho in the ascidian egg. Dev Growth Differ 45:275-281.
29. Zhu ZY, Chen DY, Li JS, Lian L, Lei L, Han ZM, Sun QY. 2003. Rotation of meiotic spindle is controlled by microfilaments in mouse oocytes. Biol Reprod 68:943-946.