Prostaglandin production from arachidonic acid and evidence for a 9,11-endoperoxide prostaglandin H2 reductase in Leishmania

International Journal for Parasitology

Volumn 32, Issue 14, 2002, Pages 1693-1700

  Kabututu, Zakayi ^a,g   Martin, Samuel K ^h   Nozaki, Tomoyoshi ^b   Kawazu, Shin Ichiro ^c   Okada, Tetsuya ^d   Munday, Craig Joe ^a   Duszenko, Michael ^e   Lazarus, Michael ^a   Thuita, Lucy W ^f   Urade, Yoshihiro ^a   Kubata, Bruno Kilunga ^a  

^a OSAKA BIOSCIENCE INSTITUTE   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c NATIONAL CENTER FOR GLOBAL HEALTH AND MEDICINE   (Japan)

^d OSAKA UNIVERSITY   (Japan)

^e UNIVERSITY OF TÜBINGEN   (Germany)

^f GEORGETOWN UNIVERSITY   (United States)

^g OSAKA UNIVERSITY   (Japan)

^h NONE

Author keywords

Arachidonic acid metabolism; Kinetoplastid; Leishmania; Prostaglandin F2 synthase; Prostaglandin production; Trypanosomatid

Indexed keywords

9,11 ENDOPEROXIDE PROSTAGLANDIN H2 REDUCTASE; ACETYLSALICYLIC ACID; ARACHIDONIC ACID; COMPLEMENTARY DNA; INDOMETACIN; OXIDOREDUCTASE; PROSTAGLANDIN; PROSTAGLANDIN F2 ALPHA SYNTHASE; SYNTHETASE; UNCLASSIFIED DRUG; 15 HYDROXYPROSTAGLANDIN DEHYDROGENASE; PROSTAGLANDIN D2 11 KETOREDUCTASE; PROSTAGLANDIN H; PROSTAGLANDIN H2; PROSTAGLANDIN-F SYNTHASE; PROTOZOAL DNA; RECOMBINANT PROTEIN;

LEISHMANIASIS; PARASITOLOGY;

ARTICLE; CATALYSIS; CONTROLLED STUDY; CYTOSOL; DATA BASE; DNA SEQUENCE; ENZYME ANALYSIS; HEAT SENSITIVITY; IMMUNOFLUORESCENCE; LEISHMANIA; LEISHMANIA DONOVANI; LEISHMANIA MAJOR; LEISHMANIA TROPICA; MOLECULAR CLONING; MOLECULAR WEIGHT; NONHUMAN; POLYMERASE CHAIN REACTION; PROMASTIGOTE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; REDUCTION; TRYPANOSOMA BRUCEI; WESTERN BLOTTING; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CLASSIFICATION; ENZYMOLOGY; GENETICS; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE;

LEISHMANIA DONOVANI; LEISHMANIA MAJOR; LEISHMANIA TROPICA; TRYPANOSOMA; TRYPANOSOMA BRUCEI; TRYPANOSOMATIDAE;

ANIMALS; ARACHIDONIC ACID; BASE SEQUENCE; BLOTTING, WESTERN; DNA, COMPLEMENTARY; DNA, PROTOZOAN; HYDROXYPROSTAGLANDIN DEHYDROGENASES; LEISHMANIA; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; PROSTAGLANDIN H2; PROSTAGLANDINS; PROSTAGLANDINS H; RECOMBINANT PROTEINS; TRYPANOSOMA BRUCEI BRUCEI;

EID: 17944396062     PISSN: 00207519     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0020-7519(02)00160-1     Document Type: Article

References (34)

1. Bailey J.M., Bryant R.W., Low C.E., Pupillo M.B., Vanderhoek J.Y. Regulation of T-lymphocyte mitogenesis by the leucocyte product 15-hydroxyeicosatetraenoic acid (15-HETE). Cell. Immunol. 67:1982;112-120.
2. Chattopadhayay R., Kaur S., Gangluy N.K., Mahajan R.C. Antigenic differences between axenic amastigotes and promastigotes of Leishmania donovani. Indian J. Med. Res. 104:1996;349-354.
3. Dubois R.N., Abramson S.B., Crofford L., Gupta R.A., Simon L.S., Van de Putte L.B., Lipsky P.E. Cyclooxygenase in biology and disease. FASEB J. 12:1998;1063-1073.
4. Ellis K.J., Morrison J.F. Buffers of constant ionic strength for studying pH-dependent processes. Methods Enzymol. 87:1982;405-426.
5. Farrell J.P., Kirkpatrick C.E. Experimental cutaneous leishmaniasis. II. A possible role for prostaglandins in exacerbation of disease in Leishmania major-infected BALB/c mice. J. Immunol. 138:1987;902-907.
6. Gemsa D., Seitz M., Menzel J., Grimm W., Kramer W., Till G. Modulation of phagocytosis-induced prostaglandin release from macrophages. Adv. Exp. Med. Biol. 114:1979;421-426.
7. Glew R.H. Prostaglandins and thromboxanes. Devlin T.M. Texbook of Biochemistry with Clinical Correlations. 1992;461-466 Wiley-Liss, New York, NY.
8. Goetzl E.J. Selective feedback of the 5-lipoxygenation of arachidonic acid in human T-lymphocytes. Biochem. Biophys. Res. Commun. 101:1981;344-350.
9. Gutierrez Y., Maksem J.A., Reiner N.E. Pathological changes in murine leishmaniasis (Leishmania donovani) with specific reference to the dynamics of granuloma formation in the liver. Am. J. Pathol. 114:1984;222-230.
10. Handman E., Jarvis H.M., Michell G.F. Leishmania major identification of stage-specific antigens and antigens shared by promastigotes and amastigotes. Parasite Immunol. 6:1984;223-233.
11. Handman E., Osborn A.H., Symons F.M., Van Driel R., Cappai R. The Leishmania promastigote surface antigen 2 complex is differentially expressed during the parasite life cycle. Mol. Biochem. Parasitol. 74:1995;189-200.
12. 2. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 355:2000;275-280.
13. Humes J.L., Bonney R.J., Pelus L., Dahlgren M.E., Sadowski S.J., Kuehl F.A., Davis P. Macrophages synthesize and release prostaglandins in response to inflammatory stimuli. Nature. 269:1977;149-151.
14. Ibrahim M.E., Lambson B., Yousif A.O., Deifalla N.S., Alnaiem D.A., Ismail A., Yousif H., Ghalib H.W., Khalil E.A., Kadaro A., Barker D.C., El Hassan A.M. Kala-azar in a high transmission focus: an ethnic and geographic dimension. Am. J. Trop. Med. Hyg. 61:1999;941-944.
15. Jensen A.T., Kemp K., Theander T.G., Handman E. Cloning, expression and antigenicity of the L. donovani reductase. APMIS. 109:2001;461-468.
16. Kidane G.Z., Samaras N., Spithill T.W. Cloning of developmentally regulated genes from Leishmania major and expression following heat induction. J. Biol. Chem. 264:1989;4244-4250.
17. Kubata B.K., Eguchi N., Urade Y., Yamashita K., Mitamura T., Tai K., Hayaishi O., Horii T. Plasmodium falciparum produces substances that are pyrogenic, somnogenic, and immunosuppressive in humans. J. Exp. Med. 188:1998;1197-1202.
18. 2α synthase in Trypanosoma brucei. J. Exp. Med. 192:2000;1327-1337.
19. Lamontagne J., Papadopoulou B. Developmental regulation of spliced leader RNA gene in Leishmania donovani amastigotes is mediated by specific polyadenylation. J. Biol. Chem. 274:1999;6602-6609.
20. Mathe A.A., Hedqvist P., Strandberg K., Leslie C.A. Aspects of prostaglandin function in the lung (second of two parts). N. Engl. J. Med. 296:1977;910-914.
21. Morley J. Role of prostaglandins secreted by macrophages in the inflammatory process. Lymphokines. 4:1981;377-383.
22. Murray H.W., Masur H., Keithly J.S. Cell-mediated immune response in experimental visceral leishmaniasis. I. Correlation between resistance to Leishmania donovani and lymphokine-generating capacity. J. Immunol. 129:1982;344-350.
23. Oliw E., Granstrom E., Anggard E. The prostaglandin and essential fatty acids. Pace-Asciak C., Granstrom E. Prostaglandins and Related Substances. 1983;11-19 Elsevier, Amsterdam.
24. Payan D.G., Goetzl E.J. Specific suppression of human T-lymphocyte function by leukotriene B4. J. Immunol. 131:1983;551-553.
25. Pimenta P.F.P., Saraiva E.M.B., Rowton E., Modi G.B., Garraway L.A., Beverley S.M., Turco S.J., Sacks D.L. Evidence that the vectorial competence of phlebotomine sand flies for different species of Leishmania is controlled by structural polymorphisms in the surface lipophosphoglycan. Proc. Natl Acad. Sci. USA. 91:1994;9155-9159.
26. Prusch R.D., Goette S.M., Haberman P. Prostaglandins may play a signal-coupling role during phagocytosis in Amoeba proteus. Cell Tissue Res. 255:1989;553-557.
27. Reiner N.E. Host-parasite relationship in murine leishmaniasis donovani: dynamics of pathophysiologic and immunologic changes. Infect. Immun. 38:1982;1223-1230.
28. Reiner N.E., Finke J.H. Interleukin 2 deficiency in murine leishmaniasis donovani and its relationship to depressed spleen cell responses to phytohemagglutinin. J. Immunol. 131:1983;1487-1491.
29. Roberts L.J., Foote S.J., Handman E. A new standard for the assessment of disease progression in murine cutaneous leishmaniasis. Parasite Immunol. 22:2000;231-237.
30. Sacks D.L., Kamhawi S. Molecular aspects of parasite-vector and vector-host interactions in leishmaniasis. Annu. Rev. Microbiol. 55:2001;453-483.
31. Sacks D.L., Modi G., Rowton E., Spath G., Epstein L., Turco S., Beverley S.M. The role of phosphoglycans in Leishmania-sand fly interactions. Proc. Natl Acad. Sci. USA. 97:2000;406-411.
32. Samaras N., Spithill T.W. The developmentally regulated P100/11E gene of Leishmania major shows homology to a superfamily of reductase genes. J. Biol. Chem. 264:1989;4251-4254.
33. Samuelsson B. Prostaglandins, thromboxans, and leukotrienes: formation and biological roles. Harvey Lect. 75:1979-1980;1-40.
34. World Health Organization, 2001. Leishmaniasis: the disease and its impact. WHO Homepage available at http://www.who.int/.