Plasmodium falciparum produces prostaglandins that are pyrogenic, somnogenic, and immunosuppressive substances in humans

Journal of Experimental Medicine

Volumn 188, Issue 6, 1998, Pages 1197-1202

  Kubata, B Kilunga ^a   Eguchi, Naomi ^b   Urade, Yoshihiro ^a   Yamashita, Kouwa ^c   Mitamura, Toshihide ^d   Tai, Kumiko ^d   Hayaishi, Osamu ^a   Horii, Toshihiro ^d  

^a OSAKA BIOSCIENCE INSTITUTE   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c NIPPON KAYAKU CO LTD   (Japan)

^d OSAKA UNIVERSITY   (Japan)

Author keywords

Malaria pathogenesis; Plasmodium falciparum; Prostaglandin; Pyrogen; Tumor necrosis factor

Indexed keywords

ARTICLE; FEVER; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; IMMUNE DEFICIENCY; MALARIA; PATHOGENESIS; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

ANIMALS; ARACHIDONIC ACID; DINOPROST; DINOPROSTONE; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; IMMUNOSUPPRESSIVE AGENTS; PLASMODIUM FALCIPARUM; PROSTAGLANDIN D2; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; PYROGENS; SHEEP; SLEEP; SPECIES SPECIFICITY;

EID: 0032555940     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.188.6.1197     Document Type: Article

References (25)

1. Ho, M., H.K. Webster, S. Looareesuwan, W. Supanaranond, R.E. Phillips, P. Chanthavanich, and D.A. Warrell. 1986. Antigen-specific immunosuppression in human malaria due to Plasmodium falciparum. J. Infect. 153:763-771.
2. Riley, E.M., G. Andersson, L.N. Otoo, S. Jepsen, and B.M. Greenwood. 1988. Cellular immune responses to Plasmodium falciparum antigens in Gambian children during and after an acute attack of falciparum malaria. Clin. Exp. Immunol. 73:17-22.
3. Whittle, H.C., J. Brown, K. Marsh, M. Blackman, O. Jobe, and F. Shenton. 1990. The effects of Plasmodium falciparum malaria on immune control of B lymphocytes in Gambian children. Clin. Exp. Immunol. 80:213-218.
4. Clark, I.A., K.A. Rockett, and W.B. Cowden. 1992. TNF and malaria. In Tumor Necrosis Factors: The Molecules and Their Emerging Role in Medicine. B. Beutler, editor. Raven Press, Ltd., New York, 303-328.
5. Karunaweera, N.D., G.E. Grau, P. Gamage, R. Carter, and K.M. Mendis. 1992. Dynamics of fever and serum levels of tumor necrosis factor are closely associated during clinical paroxysms in Plasmodium vivax malaria. Proc. Natl. Acad. Sci. USA. 89:3200-3203.
6. Kwiatkowski, D., J.G. Cannon, K.R. Manogue, A. Cerami, C.A. Dinarello, and B.M. Greenwood. 1989. Tumour necrosis factor production in falciparum malaria and its association with schizont rupture. Clin. Exp. Immunol. 77:361-366.
7. Dinarello, C.A. 1987. Interleukins, tumor necrosis factors (cachectin), and interferons as endogenous pyrogens and mediators of fever. Lymphokines. 14:1-31.
8. Goodwin, J.S., and J. Ceuppens. 1983. Regulation of the immune response by prostaglandins. J. Clin. Immunol. 3:295-315.
9. Hayaishi, O., and H. Matsumura. 1995. Prostaglandins and sleep. Adv. Neuroimmunol. 5:211-216.
10. Trager, W., and J.B. Jensen. 1976. Human malaria parasites in continuous culture. Science. 193:673-675.
11. Sugiyama, T., K. Suzue, M. Okamoto, J. Inselburg, K. Tai, and T. Horii. 1996. Production of recombinant SERA proteins of Plasmodium falciparum in Escherichia coli by using synthetic genes. Vaccine. 14:1069-1076.
12. Tosta, C.E., M. Sedegah, D.C. Henderson, and N. Wedderburn. 1980. Plasmodium yoelii and Plasmodium berghei: isolation of infected erythrocytes from blood by colloidal silica gradient centrifugation. Exp. Parasitol. 50:7-15.
13. 2 formation and characterization of its synthetases in various tissues of adult rats. Arch. Biochem. Biophys. 260:521-531.
14. Miyazaki, H., M. Ishibashi, K. Yamashita, Y. Nishikawa, and M. Katori. 1981. Dimethylisopropylsilyl ether derivatives in gas chromatography mass spectrometry of prostaglandins and thromboxane B2. Biomed. Mass Spectrom. 8:521-526.
15. Barnett, J., J. Chow, D. Ives, M. Chiou, R. Mackenzie, E. Osen, B. Nguyen, S. Tsing, C. Bach, J. Freire, et al. 1994. Purification, characterization and selective inhibition of human prostaglandin G/H synthase 1 and 2 expressed in the baculovirus system. Biochim. Biophys. Acta. 1209:130-139.
16. Laneuville, O., D.K. Breuer, D.L. Dewitt, T. Hla, C.D. Funk, and W.L. Smith. 1994. Differential inhibition of human prostaglandin endoperoxide H synthase-1 and -2 by nonsteroidal anti-inflammatory drugs. J. Pharmacol. Exp. Ther. 271:927-934.
17. Hsiao, L.L., T.J. Howard, M. Aikawa, and T.F. Taraschi. 1991. Modification of host cell membrane lipid composition by the intra-erythrocytic human malaria parasite Plasmodium falciparum. Biochem. J. 274:121-132.
18. Holz, G.G., Jr. 1977. Lipids and the malarial parasite. Bull. W.H.O. 55:237-248.
19. Bate, C.A., J. Taverne, E. Roman, C. Moreno, and J.H. Playfair. 1992. Tumour necrosis factor induction by malaria exoantigens depends upon phospholipid. Immunology. 75: 129-135.
20. Clark, I.A., N.H. Hunt, G.A. Butcher, and W.B. Cowden. 1987. Inhibition of murine malaria (Plasmodium chabaudi) in vivo by recombinant interferon-gamma or tumor necrosis factor, and its enhancement by butylated hydroxyanisole. J. Immunol. 139:3493-3496.
21. Taverne, J., N. Sheikh, J.B. de Souza, J.H. Playfair, L. Probert, and G. Kollias. 1994. Anaemia and resistance to malaria in transgenic mice expressing human tumour necrosis factor. Immunology. 82:397-403.
22. 2 regulates macrophage-derived tumor necrosis factor gene expression. J. Biol. Chem. 263:5380-5384.
23. 2 and cyclic nucleotides. J. Immunol. 141:2388-2393.
24. Liu, L.X., C.N. Serhan, and P.F. Weller. 1990. Intravascular filarial parasites elaborate cyclooxygenase-derived eicosanoids. J. Exp. Med. 172:993-996.
25. Lui, L.X., and P.F. Weller. 1990. Arachidonic acid metabolism in filarial parasites. Exp. Parasitol. 71:496-501.