Identification of a novel prostaglandin F(2α) synthase in Trypanosoma brucei

Journal of Experimental Medicine

Volumn 192, Issue 9, 2000, Pages 1327-1337

  Kubata, Bruno Kilunga ^a   Duszenko, Michael ^b   Kabututu, Zakayi ^c   Rawer, Marc ^b   Szallies, Alexander ^b   Fujimori, Ko ^d   Inui, Takashi ^d   Nozaki, Tomoyoshi ^e   Yamashita, Kouwa ^f   Horii, Toshihiro ^c   Urade, Yoshihiro ^a,d   Hayaishi, Osamu ^a  

^a OSAKA BIOSCIENCE INSTITUTE   (Japan)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c OSAKA UNIVERSITY   (Japan)

^d JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^e NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^f NIPPON KAYAKU CO LTD   (Japan)

Author keywords

African trypanosomiasis; Aldo keto reductase; PG production; PGF(2 ) synthase; Trypanosoma brucei

Indexed keywords

MESSENGER RNA; PROSTAGLANDIN F2 ALPHA; PROSTAGLANDIN H2; PROSTAGLANDIN SYNTHASE;

AFRICAN TRYPANOSOMIASIS; ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ANALYSIS; GROWTH CURVE; METABOLITE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PHYLOGENY; PRIORITY JOURNAL; PROSTAGLANDIN SYNTHESIS; RAT; SYMPTOMATOLOGY; TRYPANOSOMA BRUCEI;

AMINO ACID SEQUENCE; ANIMALS; ARACHIDONIC ACID; CELL EXTRACTS; CELLS, CULTURED; CLONING, MOLECULAR; DINOPROST; DINOPROSTONE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; KINETICS; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PHYLOGENY; PROSTAGLANDIN D2; PROSTAGLANDIN H2; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS H; RECOMBINANT PROTEINS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; SUBSTRATE SPECIFICITY; TRYPANOSOMA BRUCEI BRUCEI;

EID: 0034613691     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.192.9.1327     Document Type: Article

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