The human gene for mannan-binding lectin-associated serine protease-2 (MASP-2), the effector component of the lectin route of complement activation, is part of a tightly linked gene cluster on chromosome 1p36.2-3

Genes and Immunity

Volumn 2, Issue 3, 2001, Pages 119-127

  Stover, C ^a   Endo, Y ^b   Takahashi, M ^b   Lynch, N J ^a   Constantinescu, C ^a   Vorup Jensen, T ^c   Thiel, S ^c   Friedl, H ^d   Hankeln, T ^d   Hall, R ^e   Gregory, S ^e   Fujita, T ^b   Schwaeble, W ^a  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^c AARHUS UNIVERSITY   (Denmark)

^d JOHANNES GUTENBERG UNIVERSITY   (Germany)

^e WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

Complement; Gene cluster; Lectin pathway; MASP2 gene; Serine proteases

Indexed keywords

CARRIER PROTEIN; COLLECTIN; MANNAN BINDING LECTIN ASSOCIATED SERINE PROTEINASE; SERINE PROTEINASE;

ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CHROMOSOME 1; CHROMOSOME MAP; COMPLEMENT ACTIVATION; GENETIC LINKAGE; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; PROMOTER REGION; RNA SPLICING;

BASE SEQUENCE; CARRIER PROTEINS; CHROMOSOME MAPPING; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CHROMOSOMES, HUMAN, PAIR 1; COLLECTINS; COMPLEMENT ACTIVATION; HUMANS; LINKAGE (GENETICS); MANNOSE-BINDING PROTEIN-ASSOCIATED SERINE PROTEASES; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; PROMOTER REGIONS (GENETICS); RNA SPLICING; SERINE ENDOPEPTIDASES; TRANSCRIPTION, GENETIC;

EID: 17944390152     PISSN: 14664879     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.gene.6363745     Document Type: Article

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