Extraction of Nigella sativa L. using supercritical CO2: A study of antioxidant activity of the extract

Separation Science and Technology

Volumn 40, Issue 6, 2005, Pages 1267-1275

  Machmudah, Siti ^a   Shiramizu, Yuko ^a   Goto, Motonobu ^a   Sasaki, Mitsuru ^a   Hirose, Tsutomu ^a  

^a KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Antioxidant activity; Nigella sativa L; Supercritical CO2 extraction; Thymoquinone

Indexed keywords

ANTIOXIDANTS; APPROXIMATION THEORY; EXTRACTION; SEPARATION; SOLVENTS; SPECTRUM ANALYSIS;

EXTRACTION PRESSURE; ULTRAVIOLET SPECTRUM; VISIBLE SPECTRUM;

CARBON DIOXIDE;

ADSORPTION; MASS TRANSFER; MEMBRANE;

EID: 17944382048     PISSN: 01496395     EISSN: None     Source Type: Journal    
DOI: 10.1081/SS-200053005     Document Type: Article

References (12)

1. Burits, M. and Bucar, F. (2000) Antioxidant activity of Nigella sativa essential oil. Phytother. Res., 14: 323-328.
2. Ali, B.H. and Blunden, G. (2003) Pharmacological and toxicological properties of Nigella sativa. Phytother. Res., 17: 299-305.
3. Badary, O.A. (1999) Thymoquinone attenuates ifosfamide-induced fanconi syndrome in rats and enhances its antitumor activity in mice. J. Ethnopharmacol., 67: 135-142.
4. El-Kamali, H.H., Ahmed, A.H., Mohammed, A.S., Yahia, I.A., El-Tayeb, I.H., and Ali, A.A. (1998) Antibacterial properties of essential oils from Nigella sativa seeds, Cymbopogon citatus leaves and Pulicaria undulata aerial parts. Fitoterapia, 34: 77-78.
5. Al-Ghamdi, M.S. (2001) The anti-inflammatory, analgesic and antipyretic activity of Nigella sativa. J Ethnopharmacol., 76: 45-48.
6. Mahmoud, M.R., El-Abhar, H.S., and Saleh, S. (2002) The effects of Nigella sativa oil against the liver damage induced by Schitosoma mansoni in mice. J. Ethnopharmacol., 79: 1-11.
7. Salem, M.L. and Hossain, M.S. (2000) Protective effect of black seed oil from Nigella sativa against murine cytomegalovirus infection. Int. J. Immunopharmacol., 22: 729-740.
8. Zaoui, A., Cherrah, Y., Alaoui, K., Mahassine, N., Amarouch, H., and Hassar, M. (2002) Effects of Nigella sativa fixed oil on blood homeostasis in rat. J. Ethnopharmacol., 79: 23-26.
9. Atta, M.B. (2003) Some characteristics of Nigella (Nigella sativa L.) seed cultivated in Egypt and its lipid profile. Food Chemistry. 83: 63-68.
10. Ramadan, M.F. and Morsel, J.T. (2002) Charactrization of phospolipid composition of black cumin (Nigella sativa L.) seed oil. Nahrung Food, 46: 240-244.
11. Hammerschmidt, P.A. and Pratt, D.E. (1978) Phenolic antioxidunts of dried soybeans. J. Food Science, 43: 556-559.
12. 2 and co-solvents: A study of the antioxidant action of the extract. J. Supercritical Fluids, 24: 57-76.