Decreased function of Fas in patients displaying delayed progression of HIV-induced immune deficiency

Hematology Journal

Volumn 2, Issue 4, 2001, Pages 220-227

  Bottarel, F ^a   Bonissoni, S ^a   Lucia, M B ^a   Bragardo, M ^a   Bensi, T ^a   Buonfiglio, D ^a   Mezzatesta, C ^a   DiFranco, D ^a   Balotta, C ^a   Capobianchi, M R ^a   Dianzani, I ^a   Cauda, R ^a   Dianzani, U ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

AIDS; Apoptosis; Fas; T cells

Indexed keywords

FAS ANTIGEN; GLYCOPROTEIN GP 120; MONOCLONAL ANTIBODY; VIRUS ENVELOPE PROTEIN;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ADULT; APOPTOSIS; ARTICLE; AUTOIMMUNITY; CELL DEATH; CELL LINE; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE COURSE; EVALUATION; FATHER; FEMALE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HYBRID; IMMUNE DEFICIENCY; INHERITANCE; LYMPHOCYTE; LYMPHOPROLIFERATIVE DISEASE; MALE; MOLECULE; MOTHER; PHENOTYPE; SYMPTOM; T LYMPHOCYTE;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANTIBODIES, MONOCLONAL; ANTIGENS, CD95; APOPTOSIS; CASE-CONTROL STUDIES; DISEASE PROGRESSION; FAMILY HEALTH; HIV LONG-TERM SURVIVORS; HUMANS; PROGNOSIS; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 17944365955     PISSN: 14664860     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.thj.6200105     Document Type: Article

References (39)

1. Apoptosis by death factor
2. Caspases: The executioners of apoptosis
3. Caspases: Intracellular signaling by proteolysis
4. Dominant interfering Fas gene mutations impair apoptosis in a human lymphoproliferative syndrome
5. Mutations in Fas associated with human lymphoproliferative syndrome and autoimmunity
6. Deficiency of the Fas apoptosis pathway without Fas gene mutations in pediatric patients with autoimmunity/lymphoproliferation
7. An inherited disorder of lymphocyte apoptosis: The autoimmune lymphoproliferative syndrome
8. Inherited human Caspase 10 mutations underlie defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative syndrome type II
9. Lymphoproliferative syndrome with autoimmunity: A possible genetic basis for dominant expression of the clinical manifestations
10. Deficiency of the Fas apoptosis pathway without Fas gene mutations is a familial trait predisposing to development of autoimmune diseases and cancer
11. Host factors and the pathogenesis of HIV-induced disease
12. Influence of host genes on HIV disease progression
13. Genetic restriction of AIDS pathogenesis by an SDF-1 chemokine gene variant
14. Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine
15. Genetic restriction of HIV-1 infection and progression to AIDS by a deletion allele of the CKR5 structural gene
16. Contrasting genetic influence of CCR2 and CCR5 variants on HIV-1 infection and disease progression
17. CCR2 chemokine receptor and AIDS progression
18. Accelerated apoptosis in peripheral blood mononuclear cells (PBMCs) from human immunodeficiency virus type-1 infected patients and in CD4 cross-linked PBMCs from normal individuals
19. Programmed cell death in peripheral lymphocytes in HIV-infected persons
20. High expression of APO-1 (CD95) on T lymphocytes from human immunodeficiency virus-1-infected children
21. Fas antigen stimulation induces marked apoptosis of T lymphocytes in human immunodeficiency virus-infected individuals
22. Activation of the CD95 (APO-1/Fas) system in T-cells from human immunodeficiency virus type-1-infected children
23. Sensitization of T-cells to CD95-mediated apoptosis by HIV-1 Tat and gp120
24. Human immunodeficiency virus type 1 Nef protein sensitizes CD4+ T lymphoid cells to apoptosis via upregulation of the CD95/CD95 ligand pathway
25. 1 T-cells
26. CD4 engagement induces Fas antigen-dependent apoptosis of T-cells in vivo
27. Diminished spontaneous apoptosis in lymphocytes from human immunodeficiency virus-infected long-term nonprogressors
28. Requirement for GD3 ganglioside in Fas- and ceramide-induced apoptosis
29. HIV-1 entry into quiescent primary lymphocytes: Molecular analysis reveals a labile, latente viral structure
30. Fifth mutation in human immunodeficiency virus type 1 reverse transcriptase contributes to the development of high-level resistance to zidovudine
31. The BAX gene maps to the glioma candidate region at 19q13.3, but is not altered in human gliomas
32. Apoptosis of CD8+ T-cells is mediated by macrophages through interaction of HIV gp120 with chemokine receptor CXCR4
33. CXCR4 and CD4 mediate a rapid CD95-independent cell death in CD4+ T-cells
34. Clustering of distinct autoimmune diseases associated with functional abnormalities of T cell survival in children
35. Defective T cell Fas function in patients with multiple sclerosis
36. Defective function of Fas in patients with type I (insulin-dependent) diabetes mellitus associated with other autoimmune diseases
37. Brief report: Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection
38. Genomic Structure of an attenuated quasispecies of HIV-1 from a blood transfusion donor and recipients
39. Characterization of nef sequences in long-term survivors of human immunodeficiency virus type I infection