메뉴 건너뛰기




Volumn 5, Issue 4, 2005, Pages 555-563

Development of cancer vaccines to activate cytotoxic T lymphocytes

Author keywords

Cancer vaccines; CD8; CTL; Dendritic cells; Tolerance; Tumour associated antigens

Indexed keywords

ANGIOPOIETIN RECEPTOR; ANTIBODY; ANTIGEN; CANCER VACCINE; CD64 ANTIGEN; CD8 ANTIGEN; CYTOKINE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DENDRITIC CELL VACCINE; DNA; DNA VACCINE; EPITOPE; FC RECEPTOR; GLYCOPROTEIN GP 96; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HEAT SHOCK PROTEIN; MACROPHAGE INFLAMMATORY PROTEIN 1; MANNOSE RECEPTOR; MONOCLONAL ANTIBODY B11; PEPTIDE; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

EID: 17844408717     PISSN: 14712598     EISSN: None     Source Type: Journal    
DOI: 10.1517/14712598.5.4.555     Document Type: Review
Times cited : (13)

References (65)
  • 1
    • 0033103021 scopus 로고    scopus 로고
    • A new era for cancer immunotherapy based on the genes that encode cancer antigens
    • ROSENBERG SA: A New era for cancer immunotherapy based on the genes that encode cancer antigens. Immunity (1999) 10(3):281-287.
    • (1999) Immunity , vol.10 , Issue.3 , pp. 281-287
    • Rosenberg, S.A.1
  • 2
    • 0035893387 scopus 로고    scopus 로고
    • Depletion of CD25+CD4+ T cells and treatment with tyrosinase-related protein 2-transduced dendritic cells enhance the interferon α-induced, CD8+ T-cell-dependent immune defense of B16 melanoma
    • STEITZ J, BKUCK J, LENZ J, KNOP J, TUTING T: Depletion of CD25+CD4+ T cells and treatment with tyrosinase-related protein 2-transduced dendritic cells enhance the interferon α-induced, CD8+ T-cell-dependent immune defense of B16 melanoma. Cancer Res. (2001) 61:8643-8646.
    • (2001) Cancer Res. , vol.61 , pp. 8643-8646
    • Steitz, J.1    Bkuck, J.2    Lenz, J.3    Knop, J.4    Tuting, T.5
  • 3
    • 0036858838 scopus 로고    scopus 로고
    • Depletion of CD25+ regulatory cells uncovers immune responses to shared tumor rejection antigens
    • GOLGHER D, JONES E, POWRIE F, ELLIOTT T, GALLIMORE A: Depletion of CD25+ regulatory cells uncovers immune responses to shared tumor rejection antigens. Eur. J. Immunol. (2002) 32:3267-3275.
    • (2002) Eur. J. Immunol. , vol.32 , pp. 3267-3275
    • Golgher, D.1    Jones, E.2    Powrie, F.3    Elliott, T.4    Gallimore, A.5
  • 4
    • 0034889233 scopus 로고    scopus 로고
    • Functional avidity maturation of CD8+ T cells without selection of higher affinity TCR
    • SLIFKA MK, WHITTON JL: Functional avidity maturation of CD8+ T cells without selection of higher affinity TCR. Nat. Immunol. (2001) 2(8):711-717.
    • (2001) Nat. Immunol. , vol.2 , Issue.8 , pp. 711-717
    • Slifka, M.K.1    Whitton, J.L.2
  • 5
    • 1542514719 scopus 로고    scopus 로고
    • Concomitant helper response rescues otherwise low avidity CD8+ memory CTLs to become efficient effectors in vivo
    • KUMARAGURU U, SUVAS S, BISWAS PS, AZKUR AK, ROUSE BT: Concomitant helper response rescues otherwise low avidity CD8+ memory CTLs to become efficient effectors in vivo. J. Immunol. (2004) 172:3719-3724.
    • (2004) J. Immunol. , vol.172 , pp. 3719-3724
    • Kumaraguru, U.1    Suvas, S.2    Biswas, P.S.3    Azkur, A.K.4    Rouse, B.T.5
  • 7
    • 0030014002 scopus 로고    scopus 로고
    • T-cell-receptor affinity and thymocyte positive selection
    • ALAM SM, TRAVERS PJ, WUNG JL et al.: T-cell-receptor affinity and thymocyte positive selection. Nature (1996) 381:616-620.
    • (1996) Nature , vol.381 , pp. 616-620
    • Alam, S.M.1    Travers, P.J.2    Wung, J.L.3
  • 8
    • 17844365973 scopus 로고    scopus 로고
    • Improved immunogenicity if a self tumor antigen by covalent linkage to CD40 ligand
    • FRENCH RR, CHAN HT, TUTT AL, GLENNIE MJ: Improved immunogenicity if a self tumor antigen by covalent linkage to CD40 ligand. Int. J. Cancer (1999) 108:896-703.
    • (1999) Int. J. Cancer , vol.108 , pp. 896-1703
    • French, R.R.1    Chan, H.T.2    Tutt, A.L.3    Glennie, M.J.4
  • 9
    • 0041825396 scopus 로고    scopus 로고
    • In vitro co-stimulation with anti-CD28 synergizes with IL12 in the generation of T cell immune responses to leukuemic cells; a strategy for ex-vivo generation of CTLs for immunotherapy
    • ORLEANS-LINDSY JK, DERU A, CRAIG JI, PRENTICE HG, LOWDELL MW: In vitro co-stimulation with anti-CD28 synergizes with IL12 in the generation of T cell immune responses to leukuemic cells; a strategy for ex-vivo generation of CTLs for immunotherapy. Clin. Exp. Immunol. (2003) 133:467-475.
    • (2003) Clin. Exp. Immunol. , vol.133 , pp. 467-475
    • Orleans-Lindsy, J.K.1    Deru, A.2    Craig, J.I.3    Prentice, H.G.4    Lowdell, M.W.5
  • 10
    • 1542405768 scopus 로고    scopus 로고
    • NK and CD8+ T cell-mediated eradication of poorly immunogenic B16-F10 melanoma by the combined action of IL-12 gene therapy and 4-IBB costimulation
    • XU D, GU P, PAN PY et al.: NK and CD8+ T cell-mediated eradication of poorly immunogenic B16-F10 melanoma by the combined action of IL-12 gene therapy and 4-IBB costimulation. Int. J. Cancer (2004) 109:499-506.
    • (2004) Int. J. Cancer , vol.109 , pp. 499-506
    • Xu, D.1    Gu, P.2    Pan, P.Y.3
  • 11
    • 1642316449 scopus 로고    scopus 로고
    • The CD8+ T cell repertoire against Her-2/neu antigens in neu transgenic mice is of low avidity with antitumor activity
    • LUSTGARTEN J, DOMINGUEZ AL, CUADROS C: The CD8+ T cell repertoire against Her-2/neu antigens in neu transgenic mice is of low avidity with antitumor activity. Eur. J. Immunol. (2004) 34:752-761.
    • (2004) Eur. J. Immunol. , vol.34 , pp. 752-761
    • Lustgarten, J.1    Dominguez, A.L.2    Cuadros, C.3
  • 12
    • 0345535130 scopus 로고    scopus 로고
    • Selective induction of high avidity CTL by altering the balance of signals for APC
    • OH S, HODGE JW, AHLERS JD, BURKE DS, SCHLOM J, BERZOFSKY JA: Selective induction of high avidity CTL by altering the balance of signals for APC. J. Immunol. (2003) 170:2523-2530.
    • (2003) J. Immunol. , vol.170 , pp. 2523-2530
    • Oh, S.1    Hodge, J.W.2    Ahlers, J.D.3    Burke, D.S.4    Schlom, J.5    Berzofsky, J.A.6
  • 13
    • 0141707939 scopus 로고    scopus 로고
    • ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells
    • GUERMONPREZ P, SAVEANU L, KLEIJMEER M et al.: ER-phagosome fusion defines an MHC class I cross-presentation compartment in dendritic cells. Nature (2003) 425(6956):397-402.
    • (2003) Nature , vol.425 , Issue.6956 , pp. 397-402
    • Guermonprez, P.1    Saveanu, L.2    Kleijmeer, M.3
  • 14
    • 18344405138 scopus 로고    scopus 로고
    • Phagosomes are competent organelles for antigen cross presentation
    • HOUDE M, BERTHOLET S, GAGNON E et al.: Phagosomes are competent organelles for antigen cross presentation. Nature (2003) 425(6956):402-406.
    • (2003) Nature , vol.425 , Issue.6956 , pp. 402-406
    • Houde, M.1    Bertholet, S.2    Gagnon, E.3
  • 15
    • 0033559238 scopus 로고    scopus 로고
    • Modulation of proteasomal activity required for the generation of a cytotoxic T lymphocyte-defined peptide derived from the tumor antigen MAGE-3
    • VALMORI D, GILEADI U, SERVIS C et al.: Modulation of proteasomal activity required for the generation of a cytotoxic T lymphocyte-defined peptide derived from the tumor antigen MAGE-3. J. Exp. Med. (1999) 189:895-906.
    • (1999) J. Exp. Med. , vol.189 , pp. 895-906
    • Valmori, D.1    Gileadi, U.2    Servis, C.3
  • 16
    • 18544373394 scopus 로고    scopus 로고
    • CD8(+) T cell responses against a dominant cryptic HLA-A2 epitope after NY-ESO-1 peptide immunization of cancer patients
    • GNJATIC S, JAGER E, CHEN W et al.: CD8(+) T cell responses against a dominant cryptic HLA-A2 epitope after NY-ESO-1 peptide immunization of cancer patients. Proc. Natl. Acad. Sci. USA (2002) 99:11813-11818.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 11813-11818
    • Gnjatic, S.1    Jager, E.2    Chen, W.3
  • 17
    • 0030822869 scopus 로고    scopus 로고
    • Immunotherapy: Fusion induces tumour rejection
    • HART I, COLACO C: Immunotherapy: fusion induces tumour rejection. Nature (1997) 388:626-627.
    • (1997) Nature , vol.388 , pp. 626-627
    • Hart, I.1    Colaco, C.2
  • 18
    • 0030904482 scopus 로고    scopus 로고
    • Induction of anti-tumor activity by immunization with fusions of dendritic and carcinoma cells
    • GONG J, CHEN D, KASHIWABA M, KUFE M: Induction of anti-tumor activity by immunization with fusions of dendritic and carcinoma cells. Nat. Med. (1997) 3:558-561.
    • (1997) Nat. Med. , vol.3 , pp. 558-561
    • Gong, J.1    Chen, D.2    Kashiwaba, M.3    Kufe, M.4
  • 19
    • 0036734775 scopus 로고    scopus 로고
    • The treatment of patients with disseminated malignant melanoma by vaccination with autologous cell hybrids of tumor cells and dendritic cells
    • KRAUSE SW, NEUMANN C, SORURI A, MAYER S, PETERS JH, ANDREESEN R: The treatment of patients with disseminated malignant melanoma by vaccination with autologous cell hybrids of tumor cells and dendritic cells. J. Immunother. (2002) 25:421-428.
    • (2002) J. Immunother. , vol.25 , pp. 421-428
    • Krause, S.W.1    Neumann, C.2    Soruri, A.3    Mayer, S.4    Peters, J.H.5    Andreesen, R.6
  • 20
    • 0034840181 scopus 로고    scopus 로고
    • Results of a Phase I clinical trial of vaccination of glioma patients with fusions of dendritic and glioma cells
    • KIKUCHI T, AKASAKI Y, IRIE M, HOMMA S, ABE T, OHNO T: Results of a Phase I clinical trial of vaccination of glioma patients with fusions of dendritic and glioma cells. Cancer Immunol. Immunother. (2001) 50:337-344.
    • (2001) Cancer Immunol. Immunother. , vol.50 , pp. 337-344
    • Kikuchi, T.1    Akasaki, Y.2    Irie, M.3    Homma, S.4    Abe, T.5    Ohno, T.6
  • 21
    • 5144226237 scopus 로고    scopus 로고
    • Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumour lymphocytes
    • ROSENBERG SA, DUDLEY ME: Cancer regression in patients with metastatic melanoma after the transfer of autologous antitumour lymphocytes. Proc. Natl. Acad. Sci. USA (2004) 101(Suppl. 2):14639-14645.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , Issue.SUPPL. 2 , pp. 14639-14645
    • Rosenberg, S.A.1    Dudley, M.E.2
  • 22
    • 3843076572 scopus 로고    scopus 로고
    • Recruitment of different subsets of antigen-presenting cells selectively modulates DNA vaccine-elicited CD4+ and CD8+ T lymphocyte responses
    • MCKAY PF, BAROUCH DH, SANTRA S et al.: Recruitment of different subsets of antigen-presenting cells selectively modulates DNA vaccine-elicited CD4+ and CD8+ T lymphocyte responses. Eur. J. Immnnol. (2004) 34:1011-1020.
    • (2004) Eur. J. Immnnol. , vol.34 , pp. 1011-1020
    • Mckay, P.F.1    Barouch, D.H.2    Santra, S.3
  • 23
    • 0036569390 scopus 로고    scopus 로고
    • Competition between CTL narrows the immune response induced by prime-boost vaccination protocols
    • PALMOWSKI MJ, CHOI EM, HERMANS IF et al.: Competition between CTL narrows the immune response induced by prime-boost vaccination protocols. J. Immunol. (2002) 168:4391-4398.
    • (2002) J. Immunol. , vol.168 , pp. 4391-4398
    • Palmowski, M.J.1    Choi, E.M.2    Hermans, I.F.3
  • 24
    • 5144235393 scopus 로고    scopus 로고
    • Correlation between tumour regression and T cell responses in melanoma patients vaccinated with MAGE antigen
    • LONCHAY C, VAN DER BRUGGEN P, CONNEROTTE T et al.: Correlation between tumour regression and T cell responses in melanoma patients vaccinated with MAGE antigen. Proc. Natl. Acad. Sci. USA (2004) 101:14631-14638.
    • (2004) Proc. Natl. Acad. Sci. USA , vol.101 , pp. 14631-14638
    • Lonchay, C.1    Van Der Bruggen, P.2    Connerotte, T.3
  • 25
    • 0035751961 scopus 로고    scopus 로고
    • Strategies for designing and optimising new generation vaccines
    • BERZOFSKY JA, AHLERS JD, BELYAKOV IM: Strategies for designing and optimising new generation vaccines. Nat. Rev. Immunol. (2001) 1:209-217.
    • (2001) Nat. Rev. Immunol. , vol.1 , pp. 209-217
    • Berzofsky, J.A.1    Ahlers, J.D.2    Belyakov, I.M.3
  • 26
    • 0031890206 scopus 로고    scopus 로고
    • Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
    • ROSENBERG SA, YANG JC, SCHWARTZENTRUBER DJ et al.: Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nat. Med. (1998) 4(3):321-327.
    • (1998) Nat. Med. , vol.4 , Issue.3 , pp. 321-327
    • Rosenberg, S.A.1    Yang, J.C.2    Schwartzentruber, D.J.3
  • 27
    • 0038153907 scopus 로고    scopus 로고
    • Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma
    • PHAN GQ, YANG JC, SHERRY RM et al.: Cancer regression and autoimmunity induced by cytotoxic T lymphocyte-associated antigen 4 blockade in patients with metastatic melanoma. Proc. Natl. Acad. Sci. USA (2003) 100:8372-8377.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 8372-8377
    • Phan, G.Q.1    Yang, J.C.2    Sherry, R.M.3
  • 28
    • 10344234206 scopus 로고    scopus 로고
    • Recombinant modified vaccinia Ankara primes functionally activated CTL specific for a melanoma tumor antigen epitope in melanoma patients with a high risk of disease recurrence
    • SMITH CL, DUNBAR PR, MIRZA F et al.: Recombinant modified vaccinia Ankara primes functionally activated CTL specific for a melanoma tumor antigen epitope in melanoma patients with a high risk of disease recurrence. Int. J. Cancer (2005) 113:259-266.
    • (2005) Int. J. Cancer , vol.113 , pp. 259-266
    • Smith, C.L.1    Dunbar, P.R.2    Mirza, F.3
  • 29
    • 0036813389 scopus 로고    scopus 로고
    • The use of HLA class I tetramers to design a vaccination strategy for melanoma patients
    • PALMOWSK MJ, SALIO M, HERMANS IF, DUNBAR PR, CERUNDOLO V: The use of HLA class I tetramers to design a vaccination strategy for melanoma patients. Immunol. Rev. (2002) 188:155-163.
    • (2002) Immunol. Rev. , vol.188 , pp. 155-163
    • Palmowsk, M.J.1    Salio, M.2    Hermans, I.F.3    Dunbar, P.R.4    Cerundolo, V.5
  • 30
    • 0346096827 scopus 로고    scopus 로고
    • The first 1000 dendritic cell vaccines
    • RIDGWAY D: The first 1000 dendritic cell vaccines. Cancer Invest. (2003) 21:873-886.
    • (2003) Cancer Invest. , vol.21 , pp. 873-886
    • Ridgway, D.1
  • 31
    • 0036214288 scopus 로고    scopus 로고
    • Interaction of heat shock proteins with peptides and antigen presenting cells: Chaperoning of the innate and adaptive immune responses
    • SRIVASTAVA P: Interaction of heat shock proteins with peptides and antigen presenting cells: chaperoning of the innate and adaptive immune responses. Annu. Rev. Immunol. (2002) 20:395-425.
    • (2002) Annu. Rev. Immunol. , vol.20 , pp. 395-425
    • Srivastava, P.1
  • 32
    • 0037108696 scopus 로고    scopus 로고
    • Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein gp96-peptide complexes: Clinical and immunologic findings
    • BELLI F, TESTORI A, RIVOLTINI L et al.: Vaccination of metastatic melanoma patients with autologous tumor-derived heat shock protein gp96-peptide complexes: clinical and immunologic findings. J. Clin. Oncol. (2002) 20:4169-4180.
    • (2002) J. Clin. Oncol. , vol.20 , pp. 4169-4180
    • Belli, F.1    Testori, A.2    Rivoltini, L.3
  • 33
    • 12444333575 scopus 로고    scopus 로고
    • Induction of antigen cross-presentation by Toll receptors
    • DATTA SK, RAZ E: Induction of antigen cross-presentation by Toll receptors. Springer Semin. Immunopathol. (2005) 26(3):247-255.
    • (2005) Springer Semin. Immunopathol. , vol.26 , Issue.3 , pp. 247-255
    • Datta, S.K.1    Raz, E.2
  • 34
    • 12144289786 scopus 로고    scopus 로고
    • A novel human cancer vaccine elicits cellular responses to the tumor-associated antigen, human chorionic gonadotropin beta
    • HE LZ, RAMAKRISHNA V, CONNOLLY JE et al.: A novel human cancer vaccine elicits cellular responses to the tumor-associated antigen, human chorionic gonadotropin beta. Clin. Cancer Res. (2004) 10:1920-1927.
    • (2004) Clin. Cancer Res. , vol.10 , pp. 1920-1927
    • He, L.Z.1    Ramakrishna, V.2    Connolly, J.E.3
  • 35
    • 10744226740 scopus 로고    scopus 로고
    • Mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs anti-melanoma T cell responses via multiple HLA molecules
    • RAMAKRISHNA V, TREML JF, VITALE L et al.: Mannose receptor targeting of tumor antigen pmel17 to human dendritic cells directs anti-melanoma T cell responses via multiple HLA molecules. J. Immunol. (2004) 172:2845-2852,
    • (2004) J. Immunol. , vol.172 , pp. 2845-2852
    • Ramakrishna, V.1    Treml, J.F.2    Vitale, L.3
  • 36
    • 0033579698 scopus 로고    scopus 로고
    • Fcγ receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I restricted antigen presentation after immune complex internalization
    • REGNAULT A, LANKAR D, LACABANNE V et al.: Fcγ receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I restricted antigen presentation after immune complex internalization. J. Exp. Med. (1999) 189:371-380.
    • (1999) J. Exp. Med. , vol.189 , pp. 371-380
    • Regnault, A.1    Lankar, D.2    Lacabanne, V.3
  • 37
    • 0024329957 scopus 로고
    • Human monoclonal antiidiotypic antibody to the tumour associated antibody 791T/36
    • AUSTIN EB, ROBINS RA, DURRANT LG, PRICE MR, BALDWIN RW: Human monoclonal antiidiotypic antibody to the tumour associated antibody 791T/36. Immunology (1989) 67:525-530.
    • (1989) Immunology , vol.67 , pp. 525-530
    • Austin, E.B.1    Robins, R.A.2    Durrant, L.G.3    Price, M.R.4    Baldwin, R.W.5
  • 38
    • 0025992891 scopus 로고
    • Induction of delayed-hypcrsensitivity to human tumor-cells with a human monoclonal antiidiotypic antibody
    • AUSTIN EB, ROBINS RA, BALDWIN RW, DURRANT LG: Induction of delayed-hypcrsensitivity to human tumor-cells with a human monoclonal antiidiotypic antibody. J. Natl. Cancer Inst. (1991) 83(17):1245-1248.
    • (1991) J. Natl. Cancer Inst. , vol.83 , Issue.17 , pp. 1245-1248
    • Austin, E.B.1    Robins, R.A.2    Baldwin, R.W.3    Durrant, L.G.4
  • 39
    • 0026091205 scopus 로고
    • Antitumor immune-response and interleukin-2 production induced in colorectal-cancer patients by immunisation with human monoclonal antiidiotypic antibody
    • ROBINS RA, DENTON GW, HARDCASTLE JD, AUSTIN EB, BALDWIN RW, DURRANT LG: Antitumor immune-response and interleukin-2 production induced in colorectal-cancer patients by immunisation with human monoclonal antiidiotypic antibody. Cancer Res. (1991) 51(19):5425-5429.
    • (1991) Cancer Res. , vol.51 , Issue.19 , pp. 5425-5429
    • Robins, R.A.1    Denton, G.W.2    Hardcastle, J.D.3    Austin, E.B.4    Baldwin, R.W.5    Durrant, L.G.6
  • 40
    • 17844407787 scopus 로고
    • Cell-mediated response in vitro after immunization of colorectal cancer patients with a human monoclonal antiidiotypic antibody
    • DENTON GW, ROBBINS RA, DURRANT LG et al.: Cell-mediated response in vitro after immunization of colorectal cancer patients with a human monoclonal antiidiotypic antibody. Gut (1991) 32(5):A557-A557.
    • (1991) Gut , vol.32 , Issue.5
    • Denton, G.W.1    Robbins, R.A.2    Durrant, L.G.3
  • 41
    • 0028146963 scopus 로고
    • Enhanced cell mediated tumour killing in patients immunised with human monoclonal antiidiotypic antibody 105AD7
    • DURRANT LG, BUCKLEY TJ, DENTON GW et al.: Enhanced cell mediated tumour killing in patients immunised with human monoclonal antiidiotypic antibody 105AD7. Cancer Res. (1994) 54:4837-4840.
    • (1994) Cancer Res. , vol.54 , pp. 4837-4840
    • Durrant, L.G.1    Buckley, T.J.2    Denton, G.W.3
  • 42
    • 0033953007 scopus 로고    scopus 로고
    • A neoadjuvant clinical trial in colorectal cancer patients of the human anti-idiotypic antibody 105AD7, which mimics CD55
    • DURRANT LG, ARMSTRONG CM, BUCKLEY D et al.: A neoadjuvant clinical trial in colorectal cancer patients of the human anti-idiotypic antibody 105AD7, which mimics CD55. Clin. Cancer Res. (2000) 62(2):422-430.
    • (2000) Clin. Cancer Res. , vol.62 , Issue.2 , pp. 422-430
    • Durrant, L.G.1    Armstrong, C.M.2    Buckley, D.3
  • 43
    • 0033991572 scopus 로고    scopus 로고
    • 105AD7 cancet vaccine stimulates anti-tumour helper and cytotoxic T cell responses in HLA-A1,3,24 and HLA-DR 1,3,7 colorectal cancer patients
    • DURRANT LG, SPENDLOVE I, BUCKLEY DJ, ROBINS RA: 105AD7 cancet vaccine stimulates anti-tumour helper and cytotoxic T cell responses in HLA-A1,3,24 and HLA-DR 1,3,7 colorectal cancer patients. Int. J. Cancer (2000) 85(1):87-92.
    • (2000) Int. J. Cancer , vol.85 , Issue.1 , pp. 87-92
    • Durrant, L.G.1    Spendlove, I.2    Buckley, D.J.3    Robins, R.A.4
  • 44
    • 0033563002 scopus 로고    scopus 로고
    • Decay accelerating factor (CD55): A target for cancer vaccines?
    • SPENDLOVE I, LI L, CARMICHAEL J, DURRANT LG: Decay accelerating factor (CD55): a target for cancer vaccines? Cancer Res. (1999) 59(10):2282-2286.
    • (1999) Cancer Res. , vol.59 , Issue.10 , pp. 2282-2286
    • Spendlove, I.1    Li, L.2    Carmichael, J.3    Durrant, L.G.4
  • 45
    • 0033793254 scopus 로고    scopus 로고
    • A therapeutic human anti-idiotypic antibody (105AD7) mimics CD55 (decay accelerating factor) in three distinct regions
    • SPENDLOVE I, LI L, POTTER V et al.: A therapeutic human anti-idiotypic antibody (105AD7) mimics CD55 (decay accelerating factor) in three distinct regions. Eur. J. Immunol. (2000) 30:2944-2953.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 2944-2953
    • Spendlove, I.1    Li, L.2    Potter, V.3
  • 46
    • 0032831925 scopus 로고    scopus 로고
    • Increased activation of lymphocytes infiltrating primary colorectal cancers following immunisation with the anti-idiotype monoclonal antibody 105AD7
    • MAXWELL-ARMSTRONG CA, DURRANT LG, ROBINS RA et al.: Increased activation of lymphocytes infiltrating primary colorectal cancers following immunisation with the anti-idiotype monoclonal antibody 105AD7. Gut (1999) 45:593-598.
    • (1999) Gut , vol.45 , pp. 593-598
    • Maxwell-Armstrong, C.A.1    Durrant, L.G.2    Robins, R.A.3
  • 48
    • 17844367837 scopus 로고    scopus 로고
    • Randomized double-blind Phase II survival study comparing immunization with the anti-idiotypic monoclonal antibody 105AD7 against placebo in advanced colorectal cancer
    • MAXWELL-ARMSTRONG CA, DURRANT LG, RUCKLEY TJ et al.: Randomized double-blind Phase II survival study comparing immunization with the anti-idiotypic monoclonal antibody 105AD7 against placebo in advanced colorectal cancer. Br. J. Cancer (2001) 84(11):1443-1446.
    • (2001) Br. J. Cancer , vol.84 , Issue.11 , pp. 1443-1446
    • Maxwell-Armstrong, C.A.1    Durrant, L.G.2    Ruckley, T.J.3
  • 50
    • 0035342538 scopus 로고    scopus 로고
    • Human anti-idiotypic antibodies can be good immunogens as they target Fc receptors on antigen-presenting cells allowing efficient stimulation of both helper and cytotoxic T-cell responses
    • DURRANT LG, PARSONS T, MOSS R et al.: Human anti-idiotypic antibodies can be good immunogens as they target Fc receptors on antigen-presenting cells allowing efficient stimulation of both helper and cytotoxic T-cell responses. Int. J. Cancer (2001) 92:414-420.
    • (2001) Int. J. Cancer , vol.92 , pp. 414-420
    • Durrant, L.G.1    Parsons, T.2    Moss, R.3
  • 51
    • 0026540583 scopus 로고
    • An idiotypic replica of carcinoembryonic antigen inducing cellular and humoral responses directed against human colorectal tumors
    • DURRANT LG, DENTON GW, JACOBS E et al.: An idiotypic replica of carcinoembryonic antigen inducing cellular and humoral responses directed against human colorectal tumors. Int. J. Cancer (1992) 50(5):811-816.
    • (1992) Int. J. Cancer , vol.50 , Issue.5 , pp. 811-816
    • Durrant, L.G.1    Denton, G.W.2    Jacobs, E.3
  • 52
    • 4043063634 scopus 로고    scopus 로고
    • A novel CEA vaccine stimulates T cell proliferation, gammaIFN secret and CEA specific CTL responses
    • PARSONS T, SPENDLOVE I, NIRULA R et al.: A novel CEA vaccine stimulates T cell proliferation, gammaIFN secret and CEA specific CTL responses. Vaccine (2004) 22(25-26):3487-3494.
    • (2004) Vaccine , vol.22 , Issue.25-26 , pp. 3487-3494
    • Parsons, T.1    Spendlove, I.2    Nirula, R.3
  • 53
    • 0036499205 scopus 로고    scopus 로고
    • Antigen-antibody immune complexes empower dendritic cells to efficiently prime specific CD8+ CTL responses in vivo
    • SCHUURHUIS DH, IOAN-FACSINAY A, NAGELKERKEN B et al.: Antigen-antibody immune complexes empower dendritic cells to efficiently prime specific CD8+ CTL responses in vivo. J. Immunol. (2002) 168(5):2240-2246.
    • (2002) J. Immunol. , vol.168 , Issue.5 , pp. 2240-2246
    • Schuurhuis, D.H.1    Ioan-Facsinay, A.2    Nagelkerken, B.3
  • 54
    • 0035136397 scopus 로고    scopus 로고
    • A retrogen strategy for presentation of an intracellular tumour antigen as an exogenous antigen by dendritic cells induces potent antitumour T helper and CTL responses
    • YOU Z, HESTER J, ROLLINS L et al.: A retrogen strategy for presentation of an intracellular tumour antigen as an exogenous antigen by dendritic cells induces potent antitumour T helper and CTL responses. Cancer Res. (2001) 61:197-205.
    • (2001) Cancer Res. , vol.61 , pp. 197-205
    • You, Z.1    Hester, J.2    Rollins, L.3
  • 55
    • 0035328668 scopus 로고    scopus 로고
    • Targeting dendritic cells to enhance DNA vaccine potency
    • YOU Z, HUANG X, HESTER J, TOH HC, CHEN SY: Targeting dendritic cells to enhance DNA vaccine potency. Cancer Res. (2001) 61:3704-3711.
    • (2001) Cancer Res. , vol.61 , pp. 3704-3711
    • You, Z.1    Huang, X.2    Hester, J.3    Toh, H.C.4    Chen, S.Y.5
  • 56
    • 2342464166 scopus 로고    scopus 로고
    • Identification of an HLA-A*0201 cytotoxic T lymphocyte epitope specific to the endothelial antigen Tie-2
    • RAMAGE JM, METHERINGHAM R, CONN A et al.: Identification of an HLA-A*0201 cytotoxic T lymphocyte epitope specific to the endothelial antigen Tie-2. Int. J. Cancer (2004) 110:245-250.
    • (2004) Int. J. Cancer , vol.110 , pp. 245-250
    • Ramage, J.M.1    Metheringham, R.2    Conn, A.3
  • 57
    • 17844385187 scopus 로고    scopus 로고
    • DNA-Fc Fusion Vaccine targeting the endothelial antigen Tie-2
    • RAMAGE JM, METHERINGHAM R, MOSS RS et al.: DNA-Fc Fusion Vaccine targeting the endothelial antigen Tie-2. Br. J. Cancer (2003) 88(Suppl. 1):S38.
    • (2003) Br. J. Cancer , vol.88 , Issue.SUPPL. 1
    • Ramage, J.M.1    Metheringham, R.2    Moss, R.S.3
  • 58
    • 0023871150 scopus 로고
    • Enhancement of surface antigen expression on human breast carcinoma cells by recombinant human interferons
    • TRAN R, HAND PH, GREINER JW, PESTKA S, SCHOLM J: Enhancement of surface antigen expression on human breast carcinoma cells by recombinant human interferons. J. Interferon Res. (1988) 8:75-88.
    • (1988) J. Interferon Res. , vol.8 , pp. 75-88
    • Tran, R.1    Hand, P.H.2    Greiner, J.W.3    Pestka, S.4    Scholm, J.5
  • 59
    • 18544380239 scopus 로고    scopus 로고
    • Tumor-associated B7-Hi promotes T-cell apoptosis: A potential mechanism of immune evasion
    • DONG H, STROME SE, SALOMAO D et al.: Tumor-associated B7-Hi promotes T-cell apoptosis: a potential mechanism of immune evasion. Nat. Med. (2002) 8(8):793-800.
    • (2002) Nat. Med. , vol.8 , Issue.8 , pp. 793-800
    • Dong, H.1    Strome, S.E.2    Salomao, D.3
  • 60
    • 0035889934 scopus 로고    scopus 로고
    • NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment
    • ROBERTS AI, LEE L, SCHWARZ E et al.: NKG2D receptors induced by IL-15 costimulate CD28-negative effector CTL in the tissue microenvironment. J. Immunol. (2001) 167:5527-5530.
    • (2001) J. Immunol. , vol.167 , pp. 5527-5530
    • Roberts, A.I.1    Lee, L.2    Schwarz, E.3
  • 61
    • 0035882014 scopus 로고    scopus 로고
    • Targeted interleukin 2 therapy enhances protective immunity induced by an autologous oral DNA vaccine against murine melanoma
    • NIETHAMMER AG, XIANG R, RUEHLMANN JM et al.: Targeted interleukin 2 therapy enhances protective immunity induced by an autologous oral DNA vaccine against murine melanoma. Cancer Res. (2001) 61:6178-6184.
    • (2001) Cancer Res. , vol.61 , pp. 6178-6184
    • Niethammer, A.G.1    Xiang, R.2    Ruehlmann, J.M.3
  • 62
    • 7444258053 scopus 로고    scopus 로고
    • Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes
    • GARNET CT, PALENA C, CHAKARBORTY M et al.: Sublethal irradiation of human tumor cells modulates phenotype resulting in enhanced killing by cytotoxic T lymphocytes. Cancer Res. (2004) 64:7985-7994.
    • (2004) Cancer Res. , vol.64 , pp. 7985-7994
    • Garnet, C.T.1    Palena, C.2    Chakarborty, M.3
  • 63
    • 3042569675 scopus 로고    scopus 로고
    • External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine mediated T-cell killing
    • CHAKARBORTY M, ABRAMS SI, COLEMAN CN et al.: External beam radiation of tumors alters phenotype of tumor cells to render them susceptible to vaccine mediated T-cell killing. Cancer Res. (2004) 64:4328-4337.
    • (2004) Cancer Res. , vol.64 , pp. 4328-4337
    • Chakarborty, M.1    Abrams, S.I.2    Coleman, C.N.3
  • 64
    • 0035328683 scopus 로고    scopus 로고
    • Cyclophosphamide, doxorubicin and paclitaxel enhance the antitumour immune responses of granulocyte/macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerised mice
    • MACHIELS JP, REILLY RT, EMENS LA et al.: Cyclophosphamide, doxorubicin and paclitaxel enhance the antitumour immune responses of granulocyte/ macrophage-colony stimulating factor-secreting whole-cell vaccines in HER-2/neu tolerised mice. Cancer Res. (2001) 61:3689-3697.
    • (2001) Cancer Res. , vol.61 , pp. 3689-3697
    • Machiels, J.P.1    Reilly, R.T.2    Emens, L.A.3
  • 65
    • 19944419103 scopus 로고    scopus 로고
    • Activation of CD40 in cervical carcinoma cells facilitates CTL responses and augments chemotherapy-induced apoptosis
    • HILL SC, YOUDE SJ, MAN S et al.: Activation of CD40 in cervical carcinoma cells facilitates CTL responses and augments chemotherapy-induced apoptosis. J. Immunol. (2005) 174:41-50.
    • (2005) J. Immunol. , vol.174 , pp. 41-50
    • Hill, S.C.1    Youde, S.J.2    Man, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.