메뉴 건너뛰기




Volumn 8, Issue 3, 1998, Pages 227-238

Meta-analysis of studies of the CYP2D6 polymorphism in relation to lung cancer and Parkinson's disease

Author keywords

CYP2D6; Lung cancer; Meta analysis; Parkinsons disease

Indexed keywords

DEBRISOQUINE 4 HYDROXYLASE;

EID: 0031799305     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-199806000-00005     Document Type: Article
Times cited : (93)

References (81)
  • 3
    • 0029050430 scopus 로고
    • Frequency of specific cytochrome P4502D6B (CYP2D6B) mutant allele in clinically differentiated groups of patients with Parkinson's disease
    • Akhmedova SN, Pushnova EA, Yakimovsky AF, Avtonomov VV, Schwartz EI. Frequency of specific cytochrome P4502D6B (CYP2D6B) mutant allele in clinically differentiated groups of patients with Parkinson's disease. Biochem Mol Med 1995; 54:88-90.
    • (1995) Biochem Mol Med , vol.54 , pp. 88-90
    • Akhmedova, S.N.1    Pushnova, E.A.2    Yakimovsky, A.F.3    Avtonomov, V.V.4    Schwartz, E.I.5
  • 5
    • 0021130765 scopus 로고
    • Metabolic oxidation phenolvpes as markers for susceptibility to lung cancer
    • Ayesh R, Idle JR, Ritchie JC, Crothers MJ, Hetzel MR. Metabolic oxidation phenolvpes as markers for susceptibility to lung cancer. Nature 1984; 312:169-170.
    • (1984) Nature , vol.312 , pp. 169-170
    • Ayesh, R.1    Idle, J.R.2    Ritchie, J.C.3    Crothers, M.J.4    Hetzel, M.R.5
  • 6
    • 0022408175 scopus 로고
    • Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine
    • Barbeau A, Cloutier T, Roy M, Plasse L, Paris S, Poirier J. Ecogenetics of Parkinson's disease: 4-hydroxylation of debrisoquine. Lancet 1985; 2:1213-1216.
    • (1985) Lancet , vol.2 , pp. 1213-1216
    • Barbeau, A.1    Cloutier, T.2    Roy, M.3    Plasse, L.4    Paris, S.5    Poirier, J.6
  • 9
    • 0028106191 scopus 로고
    • Genetic polymorphism of cytochrome P450 2D6 in idiopathic Parkinson's disease and diffuse Lewy Body disease
    • Bordet R, Broly F, Destée A, Libersa C. Genetic polymorphism of cytochrome P450 2D6 in idiopathic Parkinson's disease and diffuse Lewy Body disease. Clin Neuropharm 1994; 17:484-488.
    • (1994) Clin Neuropharm , vol.17 , pp. 484-488
    • Bordet, R.1    Broly, F.2    Destée, A.3    Libersa, C.4
  • 10
    • 0029876756 scopus 로고    scopus 로고
    • Lack of relation between genetic polymorphism of cytochrome P450 2D6 and sporadic idiopathic Parkinson's disease
    • Bordet R, Broly F, Destée A, Libersa C, Lafitte JJ. Lack of relation between genetic polymorphism of cytochrome P450 2D6 and sporadic idiopathic Parkinson's disease. Clin Neuropharm 1996a, 19:213-221.
    • (1996) Clin Neuropharm , vol.19 , pp. 213-221
    • Bordet, R.1    Broly, F.2    Destée, A.3    Libersa, C.4    Lafitte, J.J.5
  • 11
    • 0029685631 scopus 로고    scopus 로고
    • Debrisoquine hydroxylation genotype in familial forms of idiopathic Parkinson's disease
    • Bordet R, Broly F, Destée A, Libersa C. Debrisoquine hydroxylation genotype in familial forms of idiopathic Parkinson's disease. Adv Neurology 1996b, 69:97-100.
    • (1996) Adv Neurology , vol.69 , pp. 97-100
    • Bordet, R.1    Broly, F.2    Destée, A.3    Libersa, C.4
  • 12
    • 0030047286 scopus 로고    scopus 로고
    • The effect of tobacco on lung cancer risk is dependent on CYP2D6 activity
    • Bouchardy C, Benhamou S, Dayer P. The effect of tobacco on lung cancer risk is dependent on CYP2D6 activity. Cancer Res 1996; 56:251-253.
    • (1996) Cancer Res , vol.56 , pp. 251-253
    • Bouchardy, C.1    Benhamou, S.2    Dayer, P.3
  • 13
    • 0024383540 scopus 로고
    • Lung cancer risk, occupational exposure, and debrisoquine metabolic phenotype
    • Caporaso N, Hayes RB, Dosemci M, Hoover R, Ayesh R, Hetzel M et al. Lung cancer risk, occupational exposure, and debrisoquine metabolic phenotype. Cancer Res 1989a, 49:3675-3679.
    • (1989) Cancer Res , vol.49 , pp. 3675-3679
    • Caporaso, N.1    Hayes, R.B.2    Dosemci, M.3    Hoover, R.4    Ayesh, R.5    Hetzel, M.6
  • 14
    • 0024387056 scopus 로고
    • The distribution of debrisoquine metabolic phenotypes and implications for the suggested association with lung cancer risk
    • Caporaso N, Pickle LW, Bale S, Ayesh, Hetzel M, Idle J. The distribution of debrisoquine metabolic phenotypes and implications for the suggested association with lung cancer risk. Gen Epidemiol 1989b, 6:517-524.
    • (1989) Gen Epidemiol , vol.6 , pp. 517-524
    • Caporaso, N.1    Pickle, L.W.2    Bale, S.3    Ayesh4    Hetzel, M.5    Idle, J.6
  • 16
    • 0029817869 scopus 로고    scopus 로고
    • ApoE and CYP2D6 polymorphism with and without Parkinsonism-dementia complex in the people of Chamoro. Guam
    • Chen X, Xia Y, Gresham LS, Molgaard CA, Thomas RG, Galasko D et al. ApoE and CYP2D6 polymorphism with and without Parkinsonism-dementia complex in the people of Chamoro. Guam. Neurology 1996; 47:779-784.
    • (1996) Neurology , vol.47 , pp. 779-784
    • Chen, X.1    Xia, Y.2    Gresham, L.S.3    Molgaard, C.A.4    Thomas, R.G.5    Galasko, D.6
  • 17
  • 18
    • 0031015828 scopus 로고    scopus 로고
    • The sparteine/debrisoquine (CYP2D6) oxidation polymorphism and the risk of lung cancer: A meta analysis
    • Christensen PM, Gotzsche PC, Brosen K. The sparteine/debrisoquine (CYP2D6) oxidation polymorphism and the risk of lung cancer: a meta analysis. Eur J Clin Pharmacol 1997; 51:389-393.
    • (1997) Eur J Clin Pharmacol , vol.51 , pp. 389-393
    • Christensen, P.M.1    Gotzsche, P.C.2    Brosen, K.3
  • 19
    • 0030436624 scopus 로고    scopus 로고
    • 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine is N-demethylated by cytochromes P450 2D6, 1A2 and 5A4 - Implications for susceptibility to Parkinson's disease
    • Coleman T, Ellis SW, Martin IJ, Lennard MS, Tucker GT. 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine is N-demethylated by cytochromes P450 2D6, 1A2 and 5A4 - implications for susceptibility to Parkinson's disease. J Pharmacol Exp Ther 1996; 277:685-690.
    • (1996) J Pharmacol Exp Ther , vol.277 , pp. 685-690
    • Coleman, T.1    Ellis, S.W.2    Martin, I.J.3    Lennard, M.S.4    Tucker, G.T.5
  • 21
    • 0025848338 scopus 로고
    • A tobacco smoke-derived nitrosamine 4-(methylnitrosamine)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P450 2D6
    • Crespi CL, Penman BW, Gelboin HV, Gonzalez FJ. A tobacco smoke-derived nitrosamine 4(-(methylnitrosamine)-1-(3-pyridyl)-1-butanone, is activated by multiple human cytochrome P450s including the polymorphic human cytochrome P450 2D6. Carcinogenesis 1991; 12:1197-1201.
    • (1991) Carcinogenesis , vol.12 , pp. 1197-1201
    • Crespi, C.L.1    Penman, B.W.2    Gelboin, H.V.3    Gonzalez, F.J.4
  • 22
    • 0001360416 scopus 로고    scopus 로고
    • Genetic metabolic polymorphism and the risk of cancer: A review of the literature
    • D'Errico A, Taioli E, Chen X, Vineis P. Genetic metabolic polymorphism and the risk of cancer: a review of the literature. Biomarkers 1996; 1:149-173.
    • (1996) Biomarkers , vol.1 , pp. 149-173
    • D'Errico, A.1    Taioli, E.2    Chen, X.3    Vineis, P.4
  • 24
    • 0029835547 scopus 로고    scopus 로고
    • Genetic variability of the CYP2D6 gene is not a risk factor for sporadic Parkinson's disease
    • Diedrich N, Hilger C, Goetz CG, Keipes M, Hentges F, Vieregge P et al. Genetic variability of the CYP2D6 gene is not a risk factor for sporadic Parkinson's disease. Ann Neurol 1996; 40:463-465.
    • (1996) Ann Neurol , vol.40 , pp. 463-465
    • Diedrich, N.1    Hilger, C.2    Goetz, C.G.3    Keipes, M.4    Hentges, F.5    Vieregge, P.6
  • 25
    • 0004012958 scopus 로고
    • Oxford: Oxford University Press
    • Doll R, Peto R. The cause of cancer. Oxford: Oxford University Press; 1981. p. 1221.
    • (1981) The Cause of Cancer , pp. 1221
    • Doll, R.1    Peto, R.2
  • 26
    • 0028829818 scopus 로고
    • Human CYP2D6 gene polymorphism in Slovene cancer patients and healthy controls
    • Dolzan V, Rudolf Z, Breskvar K. Human CYP2D6 gene polymorphism in Slovene cancer patients and healthy controls. Carcinogenesis 1995; 16:2675-2678.
    • (1995) Carcinogenesis , vol.16 , pp. 2675-2678
    • Dolzan, V.1    Rudolf, Z.2    Breskvar, K.3
  • 28
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey-Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. Br Med J 1997; 315:629-654.
    • (1997) Br Med J , vol.315 , pp. 629-654
    • Egger, M.1    Davey-Smith, G.2    Schneider, M.3    Minder, C.4
  • 29
    • 0025129037 scopus 로고
    • Dextromethorphan oxidation phenotypes as markers for susceptibility to lung cancer
    • Faccini GB, Puchetti V, Zatti N. Dextromethorphan oxidation phenotypes as markers for susceptibility to lung cancer. Clin Chem 1990; 36:387.
    • (1990) Clin Chem , vol.36 , pp. 387
    • Faccini, G.B.1    Puchetti, V.2    Zatti, N.3
  • 30
    • 0023568113 scopus 로고
    • MPTP the neurotoxin inducing Parkinson's disease, is a potent inhibitor of human and rat P450 enzymes (P450buf1, P450db1) catalysing debrisoquine 4-hydroxylation
    • Fonne-Pfister R, Bargetzi MJA, Meyer UA. MPTP the neurotoxin inducing Parkinson's disease, is a potent inhibitor of human and rat P450 enzymes (P450buf1, P450db1) catalysing debrisoquine 4-hydroxylation. Biochem Biophys Res Commun 1987; 148:1144-1150.
    • (1987) Biochem Biophys Res Commun , vol.148 , pp. 1144-1150
    • Fonne-Pfister, R.1    Bargetzi, M.J.A.2    Meyer, U.A.3
  • 31
    • 0028124654 scopus 로고
    • Genetic linkage studies in autosomal dominant Parkinsonism: Evaluation of seven candidate genes
    • Gasser T, Wszolek ZK, Trofatter J, Ozelius L, Uitti RJ, Lee CS et al. Genetic linkage studies in autosomal dominant Parkinsonism: evaluation of seven candidate genes. Ann Neurol 1994; 36:387-396.
    • (1994) Ann Neurol , vol.36 , pp. 387-396
    • Gasser, T.1    Wszolek, Z.K.2    Trofatter, J.3    Ozelius, L.4    Uitti, R.J.5    Lee, C.S.6
  • 33
    • 0025307264 scopus 로고
    • Poor hydroxylator phenotypes of debrisoquine and S-mephenytoin are not over-represented in a group of patients with Parkinson's disease
    • Godjonsson O, Sanz E, Alván G, Aquilonius S-M, Reveriego J. Poor hydroxylator phenotypes of debrisoquine and S-mephenytoin are not over-represented in a group of patients with Parkinson's disease. Br J Clin Pharmacol 1990; 30:301-302.
    • (1990) Br J Clin Pharmacol , vol.30 , pp. 301-302
    • Godjonsson, O.1    Sanz, E.2    Alván, G.3    Aquilonius, S.-M.4    Reveriego, J.5
  • 34
    • 0025114258 scopus 로고
    • Identification of the primary gene defect at the cytochrome P450 CYP2D locus
    • Gough AC, Miles JS, Spurr NK, Moss JE, Gaedigk A, Eichelbaum M et al. Identification of the primary gene defect at the cytochrome P450 CYP2D locus. Nature 1990; 347:773-776.
    • (1990) Nature , vol.347 , pp. 773-776
    • Gough, A.C.1    Miles, J.S.2    Spurr, N.K.3    Moss, J.E.4    Gaedigk, A.5    Eichelbaum, M.6
  • 35
    • 0023240830 scopus 로고
    • Implications of overviews of randomised trials
    • Hennekens CH, Buring JE, Hebert PR. Implications of overviews of randomised trials. Stat Med 1987; 6:397-402.
    • (1987) Stat Med , vol.6 , pp. 397-402
    • Hennekens, C.H.1    Buring, J.E.2    Hebert, P.R.3
  • 39
    • 0026080015 scopus 로고
    • Is there a link between debrisoquine oxidation phenotype and lung cancer susceptibility
    • Horsmans Y, Desager JP, Harvengt C. Is there a link between debrisoquine oxidation phenotype and lung cancer susceptibility. Biomed Pharmacother 1991; 45:359-362.
    • (1991) Biomed Pharmacother , vol.45 , pp. 359-362
    • Horsmans, Y.1    Desager, J.P.2    Harvengt, C.3
  • 42
    • 0030741819 scopus 로고    scopus 로고
    • Analysis of CYP2D6 expression in human lung: Implications for the association between CYP2D6 activity and susceptibility to lung cancer
    • Kivistö KT, Griese E-U, Stüven T, Fritz P, Friedel G, Kroemer HK et al. Analysis of CYP2D6 expression in human lung: implications for the association between CYP2D6 activity and susceptibility to lung cancer. Pharmacogenetics 1997; 7:295-302.
    • (1997) Pharmacogenetics , vol.7 , pp. 295-302
    • Kivistö, K.T.1    Griese, E.-U.2    Stüven, T.3    Fritz, P.4    Friedel, G.5    Kroemer, H.K.6
  • 43
    • 0010562675 scopus 로고
    • Association of Xba I allel (Xba I 44 kb) of the human cytochrome P-450dbI (CYP2D6) gene in Japanese patients with idiopathic Parkinson's disease
    • Nagatsu T, Narabayashi H, Yoshida M, editors. New York: Springer-Verlag
    • Kondo I, Kanazawa I. Association of Xba I allel (Xba I 44 kb) of the human cytochrome P-450dbI (CYP2D6) gene in Japanese patients with idiopathic Parkinson's disease. In: Nagatsu T, Narabayashi H, Yoshida M, editors. Parkinson's disease. From clinical aspects to molecular basis. New York: Springer-Verlag; 1991. pp. 111-117.
    • (1991) Parkinson's Disease. from Clinical Aspects to Molecular Basis , pp. 111-117
    • Kondo, I.1    Kanazawa, I.2
  • 44
    • 0027348840 scopus 로고
    • Debrisoquine hydroxylase and Parkinson's disease
    • Kondo I, Kanazawa I. Debrisoquine hydroxylase and Parkinson's disease. Adv Neurol 1993; 60:338-342.
    • (1993) Adv Neurol , vol.60 , pp. 338-342
    • Kondo, I.1    Kanazawa, I.2
  • 46
    • 0027330416 scopus 로고
    • Variant cytochrome P450 CYP2D6 allelic frequencies in Parkinson's disease
    • Kurth MC, Kurth JH. Variant cytochrome P450 CYP2D6 allelic frequencies in Parkinson's disease. Am J Med Gen 1993; 48:166-168.
    • (1993) Am J Med Gen , vol.48 , pp. 166-168
    • Kurth, M.C.1    Kurth, J.H.2
  • 47
    • 0013642531 scopus 로고
    • Lack of association of CYP2D6 and MAO-B alleles with Parkinson's disease in a Kansas cohort
    • Kurth JH, Phoenix AZ, Hubble JP. Lack of association of CYP2D6 and MAO-B alleles with Parkinson's disease in a Kansas cohort. Neurology 1995; 45: A429.
    • (1995) Neurology , vol.45
    • Kurth, J.H.1    Phoenix, A.Z.2    Hubble, J.P.3
  • 48
    • 0024334403 scopus 로고
    • Debrisoquine metabolism and genetic predisposition to lung cancer
    • Law MR, Hetzel MR, Idle JR. Debrisoquine metabolism and genetic predisposition to lung cancer. Br J Cancer 1989; 59:686-687.
    • (1989) Br J Cancer , vol.59 , pp. 686-687
    • Law, M.R.1    Hetzel, M.R.2    Idle, J.R.3
  • 49
    • 0029802706 scopus 로고    scopus 로고
    • Influence of a mutation reducing the catalytic activity of the cytochrome P450 CYP2D6 on lung cancer susceptibility
    • Legrand M, Stücker I, Marez D, Sabbagh N, Lo-Guidice JM, Broly F. Influence of a mutation reducing the catalytic activity of the cytochrome P450 CYP2D6 on lung cancer susceptibility. Carcinogenesis 1996; 17:2267-2269.
    • (1996) Carcinogenesis , vol.17 , pp. 2267-2269
    • Legrand, M.1    Stücker, I.2    Marez, D.3    Sabbagh, N.4    Lo-Guidice, J.M.5    Broly, F.6
  • 50
    • 0026667928 scopus 로고
    • Debrisoquine metabolism in Chinese patients with Alzheimer's and Parkinson's disease
    • Liu T-U, Chi C-W, Yang J-C, Cheung S-C, Liu H-C. Debrisoquine metabolism in Chinese patients with Alzheimer's and Parkinson's disease. Mol Chem Neuropathol 1992; 17:31-57.
    • (1992) Mol Chem Neuropathol , vol.17 , pp. 31-57
    • Liu, T.-U.1    Chi, C.-W.2    Yang, J.-C.3    Cheung, S.-C.4    Liu, H.-C.5
  • 51
    • 0028199908 scopus 로고
    • Methodological issues in interpretation of studies of the CYP2D6 genotype in relation to lung cancer risk
    • London SJ, Daly AK, Thomas DC, Caporaso NE, Idle JR. Methodological issues in interpretation of studies of the CYP2D6 genotype in relation to lung cancer risk. Pharmacogenetics 1994; 4:107-108.
    • (1994) Pharmacogenetics , vol.4 , pp. 107-108
    • London, S.J.1    Daly, A.K.2    Thomas, D.C.3    Caporaso, N.E.4    Idle, J.R.5
  • 52
    • 7144226319 scopus 로고    scopus 로고
    • Genetic polymorphism of CYP2D6 and lung cancer risk in African-Americans and Caucasians in Los Angeles County
    • London SJ, Daly AK, Leathart JBS, Navidi WC, Carpenter CC, Idle JR. Genetic polymorphism of CYP2D6 and lung cancer risk in African-Americans and Caucasians in Los Angeles County. Carcinogenesis 1997; 17:2267-2269.
    • (1997) Carcinogenesis , vol.17 , pp. 2267-2269
    • London, S.J.1    Daly, A.K.2    Leathart, J.B.S.3    Navidi, W.C.4    Carpenter, C.C.5    Idle, J.R.6
  • 53
    • 0029846366 scopus 로고    scopus 로고
    • Mutation frequencies of the cytochrome CYP2D6 gene in Parkinson disease patients and in families
    • Lucotte G, Turpin J-C, Gérard N, Panserat S, Krishnamoorthy R. Mutation frequencies of the cytochrome CYP2D6 gene in Parkinson disease patients and in families. Am J Med Gen 1996; 67:361-365.
    • (1996) Am J Med Gen , vol.67 , pp. 361-365
    • Lucotte, G.1    Turpin, J.-C.2    Gérard, N.3    Panserat, S.4    Krishnamoorthy, R.5
  • 54
    • 0030981089 scopus 로고    scopus 로고
    • Bad genes, good people, association linkage, and the environment
    • Luft FC. Bad genes, good people, association linkage, and the environment. J Molec Med 1997; 75:309-311.
    • (1997) J Molec Med , vol.75 , pp. 309-311
    • Luft, F.C.1
  • 58
    • 84982607571 scopus 로고
    • The Hhal polymorphism in the CYP2D6 gene is not associated with Parkinson's disease in a Caucasian population
    • Nicholl DJ, Bennet P, Ramsden DB, Ho SL, Williams AC. The Hhal polymorphism in the CYP2D6 gene is not associated with Parkinson's disease in a Caucasian population. Eur J Neurol 1995; 2:580-582.
    • (1995) Eur J Neurol , vol.2 , pp. 580-582
    • Nicholl, D.J.1    Bennet, P.2    Ramsden, D.B.3    Ho, S.L.4    Williams, A.C.5
  • 60
    • 0023279624 scopus 로고
    • Debrisoquine metabolism in Parkinsonian patients treated with antihistamine drugs
    • Poirier J, Roy M, Campanella G, Cloutier T, Paris S. Debrisoquine metabolism in Parkinsonian patients treated with antihistamine drugs. Lancet 1987; 2:386.
    • (1987) Lancet , vol.2 , pp. 386
    • Poirier, J.1    Roy, M.2    Campanella, G.3    Cloutier, T.4    Paris, S.5
  • 61
    • 0028012459 scopus 로고
    • Dextromethorphan test for evaluation of congenital predisposition to lung cancer
    • Puchetti V, Faccini GB, Micciolo R, Ghimenton F, Bertrand C, Zatti N. Dextromethorphan test for evaluation of congenital predisposition to lung cancer. Chest 1994; 105:449-453.
    • (1994) Chest , vol.105 , pp. 449-453
    • Puchetti, V.1    Faccini, G.B.2    Micciolo, R.3    Ghimenton, F.4    Bertrand, C.5    Zatti, N.6
  • 63
    • 0023795221 scopus 로고
    • Debrisoquine hydroxylation phenotype, acetylation phenotype and ABO blood groups as genetic host factors of lung cancer risk
    • Roots I, Drakoulis N, Ploch M, Heinmeyer G, Loddenkemper R, Minks T et al. Debrisoquine hydroxylation phenotype, acetylation phenotype and ABO blood groups as genetic host factors of lung cancer risk. Klin Wochensch 1988; 66 (suppl XI):87-97.
    • (1988) Klin Wochensch , vol.66 , Issue.11 SUPPL. , pp. 87-97
    • Roots, I.1    Drakoulis, N.2    Ploch, M.3    Heinmeyer, G.4    Loddenkemper, R.5    Minks, T.6
  • 64
    • 0026559089 scopus 로고
    • Mutant genes of cytochrome P-450IID6, glutathione S-transferase class mμ. and arylamine N-acetyltransferase in lung cancer patients
    • Roots I, Brockmöller J, Drakoulis N, Loddenkemper R. Mutant genes of cytochrome P-450IID6, glutathione S-transferase class mμ. and arylamine N-acetyltransferase in lung cancer patients. Clin Invest 1992; 70:307-319.
    • (1992) Clin Invest , vol.70 , pp. 307-319
    • Roots, I.1    Brockmöller, J.2    Drakoulis, N.3    Loddenkemper, R.4
  • 66
    • 0031038038 scopus 로고    scopus 로고
    • Cytochrome P450 2D6 variants in a Caucasian population: Allele frequencies and phenotypic consequences
    • Sachse C, Brockmöller J, Bauer S, Roots I. Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences. Am J Hum Genet. 1997; 60:284-295.
    • (1997) Am J Hum Genet. , vol.60 , pp. 284-295
    • Sachse, C.1    Brockmöller, J.2    Bauer, S.3    Roots, I.4
  • 69
    • 0027054926 scopus 로고
    • Molecular genetic analysis of the cytochrome P450-debrisoquine hydroxylase locus and association with cancer susceptibility
    • Smith CAD, Moss JE, Gough AC, Spurr NK, Wolf CR. Molecular genetic analysis of the cytochrome P450-debrisoquine hydroxylase locus and association with cancer susceptibility. Environ Health Prospect 1992a, 98:107-112.
    • (1992) Environ Health Prospect , vol.98 , pp. 107-112
    • Smith, C.A.D.1    Moss, J.E.2    Gough, A.C.3    Spurr, N.K.4    Wolf, C.R.5
  • 74
    • 0028810503 scopus 로고
    • CYP2D6 genotype and lung cancer risk according to histologic type and tobacco exposure
    • Stücker I, Cosme J, Laurent P, Centée S, Beaune P, Bignon J et al. CYP2D6 genotype and lung cancer risk according to histologic type and tobacco exposure. Carcinogenesis 1995; 16:2759-2764.
    • (1995) Carcinogenesis , vol.16 , pp. 2759-2764
    • Stücker, I.1    Cosme, J.2    Laurent, P.3    Centée, S.4    Beaune, P.5    Bignon, J.6
  • 76
    • 0027200680 scopus 로고
    • A novel cytochrome P-450IID6 mutant gene associated with Parkinson's disease
    • Tsuneoka Y, Matsuo Y, Iwahashi K, Takeuchi H, Ichikawa Y. A novel cytochrome P-450IID6 mutant gene associated with Parkinson's disease. J Biochem 1993; 114:263-266.
    • (1993) J Biochem , vol.114 , pp. 263-266
    • Tsuneoka, Y.1    Matsuo, Y.2    Iwahashi, K.3    Takeuchi, H.4    Ichikawa, Y.5
  • 77
    • 0030980786 scopus 로고    scopus 로고
    • Cigarette smoking and lung cancer trends. A light at the end of the tunnel?
    • Weiss W. Cigarette smoking and lung cancer trends. A light at the end of the tunnel? Chest 1997; 111:1414-1416.
    • (1997) Chest , vol.111 , pp. 1414-1416
    • Weiss, W.1
  • 78
    • 0026776502 scopus 로고
    • Relationship between the debrisoquine hydroxylase polymorphism and cancer susceptibility
    • Wolf CR, Smith CAD, Gough AC, Moss JE, Valliss KA, Howard G et al. Relationship between the debrisoquine hydroxylase polymorphism and cancer susceptibility. Carcinogenesis 1992; 13:1035-1038.
    • (1992) Carcinogenesis , vol.13 , pp. 1035-1038
    • Wolf, C.R.1    Smith, C.A.D.2    Gough, A.C.3    Moss, J.E.4    Valliss, K.A.5    Howard, G.6
  • 80
    • 84960989652 scopus 로고
    • On estimating the relation between blood group and disease
    • Woolf B. On estimating the relation between blood group and disease. Ann Hum Genet 1955; 19:251-253.
    • (1955) Ann Hum Genet , vol.19 , pp. 251-253
    • Woolf, B.1
  • 81
    • 0021909115 scopus 로고
    • Beta blockage during and after myocardial infarction: An overview of the randomized trials
    • Yusuf S, Peto R, Lewis J, Collins R, Steight P. Beta blockage during and after myocardial infarction: an overview of the randomized trials. Prog Cardiovasc Dis 1985; 27:335-371.
    • (1985) Prog Cardiovasc Dis , vol.27 , pp. 335-371
    • Yusuf, S.1    Peto, R.2    Lewis, J.3    Collins, R.4    Steight, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.