-
1
-
-
0028875109
-
Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation
-
Burchell B, Brierley CH, and Rance D (1995) Specificity of human UDP-glucuronosyltransferases and xenobiotic glucuronidation. Life Sci 57:1819-1831.
-
(1995)
Life Sci
, vol.57
, pp. 1819-1831
-
-
Burchell, B.1
Brierley, C.H.2
Rance, D.3
-
2
-
-
0031704509
-
Species differences in N-glucuronidation
-
Chiu SH and Huskey SW (1998) Species differences in N-glucuronidation. Drug Metab Dispos 26:838-847.
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 838-847
-
-
Chiu, S.H.1
Huskey, S.W.2
-
3
-
-
0027451525
-
N-Glucuronidation reaction. I. Tetrazole N-glucuronidation of selected angiotensin II receptor antagonists in hepatic microsomes from rats, dogs, monkeys and humans
-
Huskey SE, Miller RR, and Chiu SH (1993) N-Glucuronidation reaction. I. Tetrazole N-glucuronidation of selected angiotensin II receptor antagonists in hepatic microsomes from rats, dogs, monkeys and humans. Drug Metab Dispos 21:792-799.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 792-799
-
-
Huskey, S.E.1
Miller, R.R.2
Chiu, S.H.3
-
4
-
-
4644369770
-
Simultaneous expression of Guinea pig UDP-glucuronosyltransferase 2B21 (UGT2B21) and 2B22 in COS-7 cells enhances UGT2B21-catalyzed chloramphenicol glucuronidation
-
Ishii Y, Miyoshi A, Maji D, Yamada H, and Oguri K (2004) Simultaneous expression of Guinea pig UDP-glucuronosyltransferase 2B21 (UGT2B21) and 2B22 in COS-7 cells enhances UGT2B21-catalyzed chloramphenicol glucuronidation. Drug Metab Dispos 32:1057-1060.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 1057-1060
-
-
Ishii, Y.1
Miyoshi, A.2
Maji, D.3
Yamada, H.4
Oguri, K.5
-
5
-
-
0036181542
-
N-Glucuronidation of some 4-arylalkyl-1H-imidazoles by rat, dog and human liver microsomes
-
Kaivosaari S, Salonen JS, and Taskinen J (2002) N-Glucuronidation of some 4-arylalkyl-1H-imidazoles by rat, dog and human liver microsomes. Drug Metab Dispos 30:295-300.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 295-300
-
-
Kaivosaari, S.1
Salonen, J.S.2
Taskinen, J.3
-
6
-
-
14044257209
-
Regioselective glucuronidation of denopamine: Marked species differences and identification of human UDP-glucuronosyltransferase isoform
-
Kaji H and Kume T (2005) Regioselective glucuronidation of denopamine: marked species differences and identification of human UDP- glucuronosyltransferase isoform. Drug Metab Dispos 33:403-412.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 403-412
-
-
Kaji, H.1
Kume, T.2
-
7
-
-
0037099357
-
Comparison of electrospray, atmospheric pressure chemical ionization, and atmospheric pressure photoionization in the identification of apomorphine, dobutamine and entacapone phase II metabolites in biological samples
-
Keski-Hynnila H, Kurkela M, Elovaara E, Antonio L, Magdalou J, Luukkanen L, Taskinen J, and Kostiainen R (2002) Comparison of electrospray, atmospheric pressure chemical ionization, and atmospheric pressure photoionization in the identification of apomorphine, dobutamine and entacapone phase II metabolites in biological samples. Anal Chem 74:3449-3457.
-
(2002)
Anal Chem
, vol.74
, pp. 3449-3457
-
-
Keski-Hynnila, H.1
Kurkela, M.2
Elovaara, E.3
Antonio, L.4
Magdalou, J.5
Luukkanen, L.6
Taskinen, J.7
Kostiainen, R.8
-
8
-
-
0037423299
-
Expression and characterization of recombinant human UDP- glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than the other UGTs and was purified as an active dimeric enzyme
-
Kurkela M, Garcia-Horsman JA, Luukkanen L, Morsky S, Taskinen J, Baumann M, Kostiainen R, Hirvonen J, and Finel M (2003) Expression and characterization of recombinant human UDP-glucuronosyltransferases (UGTs). UGT1A9 is more resistant to detergent inhibition than the other UGTs and was purified as an active dimeric enzyme. J Biol Chem 278:3536-3544.
-
(2003)
J Biol Chem
, vol.278
, pp. 3536-3544
-
-
Kurkela, M.1
Garcia-Horsman, J.A.2
Luukkanen, L.3
Morsky, S.4
Taskinen, J.5
Baumann, M.6
Kostiainen, R.7
Hirvonen, J.8
Finel, M.9
-
9
-
-
8844283291
-
The interactions between the N-terminal and C-terminal domains of the human UDP-glucuronosyltransferases are partly isoform-specific and may involve both monomers
-
Kurkela M, Hirvonen J, Kostiainen R, and Finel M (2004) The interactions between the N-terminal and C-terminal domains of the human UDP- glucuronosyltransferases are partly isoform-specific and may involve both monomers. Biochem Pharmacol 68:2443-2450.
-
(2004)
Biochem Pharmacol
, vol.68
, pp. 2443-2450
-
-
Kurkela, M.1
Hirvonen, J.2
Kostiainen, R.3
Finel, M.4
-
10
-
-
0041856580
-
Glucuronidation of anabolic androgenic steroids by recombinant human UDP-glucuronosyltransferases
-
Kuuranne T, Kurkela M, Thevis M, Schanzer W, Finel M, and Kostiainen R (2003) Glucuronidation of anabolic androgenic steroids by recombinant human UDP-glucuronosyltransferases. Drug Metab Dispos 31: 1117-1124.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 1117-1124
-
-
Kuuranne, T.1
Kurkela, M.2
Thevis, M.3
Schanzer, W.4
Finel, M.5
Kostiainen, R.6
-
11
-
-
0035112167
-
Investigation of the in vitro metabolism profile of a phosphodiesterase-IV inhibitor, CDP-840: Leading to structural optimization
-
Li C, Chauret N, Trimble LA, Nicoll-Griffith DA, Silva JM, MacDonald D, Perrier H. Yergey JA, Parton T, Alexander RP, et al. (2001) Investigation of the in vitro metabolism profile of a phosphodiesterase-IV inhibitor, CDP-840: leading to structural optimization. Drug Metab Dispos 29:232-241.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 232-241
-
-
Li, C.1
Chauret, N.2
Trimble, L.A.3
Nicoll-Griffith, D.A.4
Silva, J.M.5
MacDonald, D.6
Perrier, H.7
Yergey, J.A.8
Parton, T.9
Alexander, R.P.10
-
12
-
-
0030895678
-
Characterization of 1-hydroxypyrene as a novel marker substrate of 3-methylcholanthrene-inducible phenol UDP-glucuronosyltransferase(s)
-
Luukkanen L, Elovaara E, Lautala P, Taskinen J, and Vainio H (1997) Characterization of 1-hydroxypyrene as a novel marker substrate of 3-methylcholanthrene-inducible phenol UDP-glucuronosyltransferase(s). Pharmacol Toxicol 80:152-158.
-
(1997)
Pharmacol Toxicol
, vol.80
, pp. 152-158
-
-
Luukkanen, L.1
Elovaara, E.2
Lautala, P.3
Taskinen, J.4
Vainio, H.5
-
13
-
-
8544224973
-
The UDP glycosyltransferase gene superfamily: Recommended nomenclature update based on evolutionary divergence
-
Mackenzie PI, Owens IS, Burchell B, Bock KW, Bairoch A, Belanger A, Fournel-Gigleux S, Green M, Hum DW, Iyanagi T, et al. (1997) The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence. Pharmacogenetics 7:255-269.
-
(1997)
Pharmacogenetics
, vol.7
, pp. 255-269
-
-
Mackenzie, P.I.1
Owens, I.S.2
Burchell, B.3
Bock, K.W.4
Bairoch, A.5
Belanger, A.6
Fournel-Gigleux, S.7
Green, M.8
Hum, D.W.9
Iyanagi, T.10
-
15
-
-
0036233667
-
Glucuronidation of statins in animals and humans: A novel mechanism of statin lactonization
-
Prueksaritanont T, Subramanian R, Fang X, Ma B, Qiu Y, Lin JH, Pearson PG, and Baillie TA (2002) Glucuronidation of statins in animals and humans: a novel mechanism of statin lactonization. Drug Metab Dispos 30:505-512.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 505-512
-
-
Prueksaritanont, T.1
Subramanian, R.2
Fang, X.3
Ma, B.4
Qiu, Y.5
Lin, J.H.6
Pearson, P.G.7
Baillie, T.A.8
-
16
-
-
0034534895
-
Roles of glucuronidation and UDP-glucuronosyltransferases in xenobiotic bioactivation reactions
-
Ritter JK (2000) Roles of glucuronidation and UDP- glucuronosyltransferases in xenobiotic bioactivation reactions. Chem-Biol Interact 129:171-193.
-
(2000)
Chem-Biol Interact
, vol.129
, pp. 171-193
-
-
Ritter, J.K.1
-
17
-
-
0035197349
-
Pharmacokinetics and metabolism of a RAS farnesyl transferase inhibitor in rats and dogs: In vitro-in vivo correlation
-
Singh R, Chen IW, Jin L, Silva MV, Arison BH, Lin JH, and Wong BK (2001) Pharmacokinetics and metabolism of a RAS farnesyl transferase inhibitor in rats and dogs: in vitro-in vivo correlation. Drug Metab Dispos 29:1578-1587.
-
(2001)
Drug Metab Dispos
, vol.29
, pp. 1578-1587
-
-
Singh, R.1
Chen, I.W.2
Jin, L.3
Silva, M.V.4
Arison, B.H.5
Lin, J.H.6
Wong, B.K.7
-
18
-
-
0034128936
-
Human UDP-glucuronosyltransferases: Metabolism, expression and disease
-
Tukey RH and Strassburg CP (2000) Human UDP-glucuronosyltransferases: metabolism, expression and disease. Annu Rev Pharmacol Toxicol 40:581-616.
-
(2000)
Annu Rev Pharmacol Toxicol
, vol.40
, pp. 581-616
-
-
Tukey, R.H.1
Strassburg, C.P.2
-
19
-
-
0036785444
-
Quaternary ammonium-linked glucuronidation of 1-substituted imidazoles by liver microsomes: Interspecies differences and structure-metabolism relationships
-
Vashishtha SC, Hawes EM, McCann DJ, Ghosheh O, and Hogg L (2002) Quaternary ammonium-linked glucuronidation of 1-substituted imidazoles by liver microsomes: interspecies differences and structure-metabolism relationships. Drug Metab Dispos 30:1070-1076.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 1070-1076
-
-
Vashishtha, S.C.1
Hawes, E.M.2
McCann, D.J.3
Ghosheh, O.4
Hogg, L.5
-
20
-
-
0036239814
-
3-O-Methyldobutamine, a major metabolite of dobutamine in humans
-
Yan M, Webster LT Jr, and Blumer JL (2002) 3-O-Methyldobutamine, a major metabolite of dobutamine in humans. Drug Metab Dispos 30:519-524.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 519-524
-
-
Yan, M.1
Webster Jr., L.T.2
Blumer, J.L.3
|