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Volumn 80, Issue 3, 1997, Pages 152-158

Characterization of 1-hydroxypyrene as a novel marker substrate of 3-methylcholanthrene-inducible phenol UDP-glucuronosyltransferase(s)

Author keywords

[No Author keywords available]

Indexed keywords

1 HYDROXYPYRENE; 3 METHYLCHOLANTHRENE; 4,4' METHYLENEBIS(2 CHLOROANILINE); ACETONE; AROCLOR 1254; CREOSOTE; DRUG METABOLITE; GLUCURONOSYLTRANSFERASE; PHENOBARBITAL; POLYCHLORINATED BIPHENYL; PYRAZOLE; PYRENE;

EID: 0030895678     PISSN: 09019928     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1600-0773.1997.tb00389.x     Document Type: Article
Times cited : (33)

References (39)
  • 1
    • 0021186825 scopus 로고
    • Kinetic properties of UDP-glucuronosyltransferase(s) in different membranes of rat liver cells
    • Antoine, B., J. Magdalou & G. Siest: Kinetic properties of UDP-glucuronosyltransferase(s) in different membranes of rat liver cells. Xenobiotica 1984, 14, 575-579.
    • (1984) Xenobiotica , vol.14 , pp. 575-579
    • Antoine, B.1    Magdalou, J.2    Siest, G.3
  • 2
    • 0027358945 scopus 로고
    • Heterogeneity of hepatic UDP-glucuronosyltransferase activities. Investigations of isoenzymes involved in p-nitrophenol glucuronidation
    • Antoine, B., J. A. Boutin & G. Siest: Heterogeneity of hepatic UDP-glucuronosyltransferase activities. Investigations of isoenzymes involved in p-nitrophenol glucuronidation. Comp. Biochem. Physiol. 1993, 106, 241-248.
    • (1993) Comp. Biochem. Physiol. , vol.106 , pp. 241-248
    • Antoine, B.1    Boutin, J.A.2    Siest, G.3
  • 3
    • 0015926539 scopus 로고
    • Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase
    • Bock, K. W., W. Fröhling, H. Remmer & B. Rexer: Effects of phenobarbital and 3-methylcholanthrene on substrate specificity of rat liver microsomal UDP-glucuronyltransferase. Biochim. Biophys. Acta 1973, 327, 46-56.
    • (1973) Biochim. Biophys. Acta , vol.327 , pp. 46-56
    • Bock, K.W.1    Fröhling, W.2    Remmer, H.3    Rexer, B.4
  • 4
    • 0022484707 scopus 로고
    • UDP-glucuronyltransferases and their toxicological significance
    • Biol. React. Intermed. III
    • Bock, K. W., B. S. Bock-Hennig, G. Fischer, W. Lilienblum & G. Schirmer: UDP-glucuronyltransferases and their toxicological significance. Adv. Exp. Med. Biol. 1986, 197 (Biol. React. Intermed. III), 171-184.
    • (1986) Adv. Exp. Med. Biol. , vol.197 , pp. 171-184
    • Bock, K.W.1    Bock-Hennig, B.S.2    Fischer, G.3    Lilienblum, W.4    Schirmer, G.5
  • 5
    • 0027075077 scopus 로고
    • Mono- And diglucuronide formation from chrysene and benzo(a)pyrene phenols by 3-methylcholantrene inducible phenol UDP-glucuronosyltransferases (UGT1A1)
    • Bock, K., H. Gschaidmeier, A. Seidel, S. Baird & B. Burchell: Mono- and diglucuronide formation from chrysene and benzo(a)pyrene phenols by 3-methylcholantrene inducible phenol UDP-glucuronosyltransferases (UGT1A1). Mol. Pharmacol. 1992, 42, 613-618.
    • (1992) Mol. Pharmacol. , vol.42 , pp. 613-618
    • Bock, K.1    Gschaidmeier, H.2    Seidel, A.3    Baird, S.4    Burchell, B.5
  • 6
    • 0021868683 scopus 로고
    • Heterogeneity of hepatic microsomal UDP-glucuronosyltransferase activities
    • Boutin, J. A., J. Thomassin, G. Siest & A. Cartier: Heterogeneity of hepatic microsomal UDP-glucuronosyltransferase activities. Biochem. Pharmacol. 1985, 34, 2235-2249.
    • (1985) Biochem. Pharmacol. , vol.34 , pp. 2235-2249
    • Boutin, J.A.1    Thomassin, J.2    Siest, G.3    Cartier, A.4
  • 8
    • 0025374018 scopus 로고
    • Evidence that a β-N-glucuronide of 4,4′-methylenebis (2-chloroaniline) (MbOCA) is a major urinary metabolite in man: Implications for biological monitoring
    • Cocker, J., A. R. Boobis, H. K. Wilson & D. Gompertz: Evidence that a β-N-glucuronide of 4,4′-methylenebis (2-chloroaniline) (MbOCA) is a major urinary metabolite in man: implications for biological monitoring. Brit. J. Ind. Med. 1990, 47, 154-161.
    • (1990) Brit. J. Ind. Med. , vol.47 , pp. 154-161
    • Cocker, J.1    Boobis, A.R.2    Wilson, H.K.3    Gompertz, D.4
  • 9
    • 0026637609 scopus 로고
    • Use of weighting functions in data fitting
    • Di Cera, E.: Use of weighting functions in data fitting. Meth. Enzymol. 1992, 210, 68-87.
    • (1992) Meth. Enzymol. , vol.210 , pp. 68-87
    • Di Cera, E.1
  • 10
    • 0027530118 scopus 로고
    • Substrate specificities of two stably expressed human liver UDP-glucuronosyltransferases of the UGT1 gene family
    • Ebner, T. & B. Burchell: Substrate specificities of two stably expressed human liver UDP-glucuronosyltransferases of the UGT1 gene family. Drug. Metab. Dispos. 1993, 21, 50-55.
    • (1993) Drug. Metab. Dispos. , vol.21 , pp. 50-55
    • Ebner, T.1    Burchell, B.2
  • 11
    • 0028923731 scopus 로고
    • Significance of dermal and respiratory uptake in creosote workers: Exposure to polycyclic aromatic hydrocarbons and urinary excretion of 1-hydroxypyrene
    • Elovaara, E., P. Heikkilä, L. Pyy, P. Mutanen & V Riihimäki: Significance of dermal and respiratory uptake in creosote workers: exposure to polycyclic aromatic hydrocarbons and urinary excretion of 1-hydroxypyrene. Occup. Environ. Med. 1995, 52, 196-203.
    • (1995) Occup. Environ. Med. , vol.52 , pp. 196-203
    • Elovaara, E.1    Heikkilä, P.2    Pyy, L.3    Mutanen, P.4    Riihimäki, V.5
  • 12
    • 85036441167 scopus 로고    scopus 로고
    • Polycyclic aromatic hydrocarbon exposure monitoring by 1-hydroxypyrene in urine of psoriasis patients undergoing coal tar treatment
    • 48th Annual meeting of Finnish Pharmacological Society: New aspects of inflammation and anti-inflammatory drugs (abstract)
    • Elovaara, E., E. Hietanen, C. Jansen & H. Vainio: Polycyclic aromatic hydrocarbon exposure monitoring by 1-hydroxypyrene in urine of psoriasis patients undergoing coal tar treatment. 48th Annual meeting of Finnish Pharmacological Society: New aspects of inflammation and anti-inflammatory drugs. Transmitteri 1996, 2, 16 (abstract).
    • (1996) Transmitteri , vol.2 , pp. 16
    • Elovaara, E.1    Hietanen, E.2    Jansen, C.3    Vainio, H.4
  • 14
    • 0020858720 scopus 로고
    • Separation, purification and characterization of three isoenzymes of UDP-glucuronosyltransferase from rat liver microsomes
    • Falany, C. N. & T. R. Tephly: Separation, purification and characterization of three isoenzymes of UDP-glucuronosyltransferase from rat liver microsomes. Arch. Biochem. Biophys. 1983, 227, 248-258.
    • (1983) Arch. Biochem. Biophys. , vol.227 , pp. 248-258
    • Falany, C.N.1    Tephly, T.R.2
  • 15
    • 0027096446 scopus 로고
    • The suitability of the urinary metabolite 1-hydroxypyrene as an index of polynuclear aromatic hydrocarbon bioavailability from workers exposed to carbon black
    • Gardiner, K., K. A. Hale, I. A. Calvert, C. Rice & J. M. Harrington: The suitability of the urinary metabolite 1-hydroxypyrene as an index of polynuclear aromatic hydrocarbon bioavailability from workers exposed to carbon black. Ann. Occup. Hyg. 1992, 36, 681-688.
    • (1992) Ann. Occup. Hyg. , vol.36 , pp. 681-688
    • Gardiner, K.1    Hale, K.A.2    Calvert, I.A.3    Rice, C.4    Harrington, J.M.5
  • 16
    • 0029051413 scopus 로고
    • Formation of mono- And diglucuronides and other glycosides of benzo(a)pyrene-3,6-quinol by V79 cell-expressed human phenol UDP-glucuronosyltransferases of the UGT1 gene complex
    • Gschaidmeier, H., A. Seidel, B. Burchell & K. W. Bock: Formation of mono- and diglucuronides and other glycosides of benzo(a)pyrene-3,6-quinol by V79 cell-expressed human phenol UDP-glucuronosyltransferases of the UGT1 gene complex. Biochem. Pharmacol. 1995, 49, 1601-1606.
    • (1995) Biochem. Pharmacol. , vol.49 , pp. 1601-1606
    • Gschaidmeier, H.1    Seidel, A.2    Burchell, B.3    Bock, K.W.4
  • 17
    • 0001036382 scopus 로고
    • Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells
    • Harding, D., S. Fournel-Giglieux, M. R. Jackson & B. Burchell: Cloning and substrate specificity of a human phenol UDP-glucuronosyltransferase expressed in COS-7 cells. Proc. Natl. Acad. Sci. 1988, 85, 8381-8385.
    • (1988) Proc. Natl. Acad. Sci. , vol.85 , pp. 8381-8385
    • Harding, D.1    Fournel-Giglieux, S.2    Jackson, M.R.3    Burchell, B.4
  • 18
    • 0001941135 scopus 로고
    • On the metabolic regulation in the glucuronic acid pathway in the rat tissues
    • Hänninen, O.: On the metabolic regulation in the glucuronic acid pathway in the rat tissues. Ann. Acad. Sci. Fenn. Ser. A II, 1968, 142, 1-96.
    • (1968) Ann. Acad. Sci. Fenn. Ser. A II , vol.142 , pp. 1-96
    • Hänninen, O.1
  • 19
    • 0023493097 scopus 로고
    • Overall evaluations of carcinogenicity: An updating of IARC Monographs Vols 1 to 42
    • IARC International Agency for Research on Cancer: Overall evaluations of carcinogenicity: an updating of IARC Monographs Vols 1 to 42. IARC Monogr. Eval. Carcinog. Risks Chem. Hum. 1987, Suppl 7.
    • (1987) IARC Monogr. Eval. Carcinog. Risks Chem. Hum. , Issue.7 SUPPL.
  • 20
    • 0027862757 scopus 로고
    • 4,4′-Methylenebis-(2-chloroaniline) (MOCA)
    • IARC International Agency for Research on Cancer, 4,4′-Methylenebis-(2-chloroaniline) (MOCA). In: IARC Monogr. Eval. Carcinog. Risks. Hum. 1993, 57, 271-303.
    • (1993) IARC Monogr. Eval. Carcinog. Risks. Hum. , vol.57 , pp. 271-303
  • 21
    • 0023137126 scopus 로고
    • Isolation and purification of two human liver UDP-glucuronosyltransferases
    • Irshaid, Y. M. & T. R. Tephly: Isolation and purification of two human liver UDP-glucuronosyltransferases. Mol. Pharmacol. 1987, 31, 27-34.
    • (1987) Mol. Pharmacol. , vol.31 , pp. 27-34
    • Irshaid, Y.M.1    Tephly, T.R.2
  • 22
    • 0023019287 scopus 로고
    • Cloning and characterization of cDNA encoding 3-methylcholanthrene inducible rat mRNA for UDP-glucuronosyltransferase
    • Iyanagi, T., M. Haniu, K. Sogawa, Y. Fujii-Kuriyama, S. Watanabe, J. E. Shively & K. F. Anan: Cloning and characterization of cDNA encoding 3-methylcholanthrene inducible rat mRNA for UDP-glucuronosyltransferase. J. Biol. Chem. 1986, 261, 15607-15614.
    • (1986) J. Biol. Chem. , vol.261 , pp. 15607-15614
    • Iyanagi, T.1    Haniu, M.2    Sogawa, K.3    Fujii-Kuriyama, Y.4    Watanabe, S.5    Shively, J.E.6    Anan, K.F.7
  • 23
    • 0026335219 scopus 로고
    • Molecular basis of multiple UDP-glucuronosyltransferase isoenzyme deficiencies in the hyperbilirubinemic rat (Gunn rat)
    • Iyanagi, T.: Molecular basis of multiple UDP-glucuronosyltransferase isoenzyme deficiencies in the hyperbilirubinemic rat (Gunn rat). J. Biol. Chem. 1991, 266, 24048-24052.
    • (1991) J. Biol. Chem. , vol.266 , pp. 24048-24052
    • Iyanagi, T.1
  • 24
    • 0024241217 scopus 로고
    • Examination of the substrate specificity of cloned rat kidney phenol UDP-glucuronosyltransferase expressed in COS-7 cells
    • Jackson, M., S. Fournel-Giglieux, D. Harding & B. Burchell: Examination of the substrate specificity of cloned rat kidney phenol UDP-glucuronosyltransferase expressed in COS-7 cells. Mol. Pharmacol. 1988, 34, 638-642.
    • (1988) Mol. Pharmacol. , vol.34 , pp. 638-642
    • Jackson, M.1    Fournel-Giglieux, S.2    Harding, D.3    Burchell, B.4
  • 25
    • 0027134662 scopus 로고
    • The glucuronidation of hydroxylated metabolites of benzo(a)pyrene and 2-acetylaminofluorene by cDNA-expressed human UDP-glucuronosyltransferases
    • Jin, C. J., J. O. Miners, B. Burchell & P. I. Mackenzie: The glucuronidation of hydroxylated metabolites of benzo(a)pyrene and 2-acetylaminofluorene by cDNA-expressed human UDP-glucuronosyltransferases. Carcinogenesis 1993, 14, 2637-2639.
    • (1993) Carcinogenesis , vol.14 , pp. 2637-2639
    • Jin, C.J.1    Miners, J.O.2    Burchell, B.3    Mackenzie, P.I.4
  • 26
    • 0028237847 scopus 로고
    • Biological monitoring of environmental exposure to polycyclic aromatic hydrocarbons; 1-hydroxypyrene in urine of people
    • Jongeneelen, F. J.: Biological monitoring of environmental exposure to polycyclic aromatic hydrocarbons; 1-hydroxypyrene in urine of people. Toxicol. Lett. 1994, 72, 205-211.
    • (1994) Toxicol. Lett. , vol.72 , pp. 205-211
    • Jongeneelen, F.J.1
  • 27
    • 0020482769 scopus 로고
    • Differential induction of rat liver microsomal UDP-glucuronosyltransferase activities by various inducing agents
    • Lilienblum, W., A. K. Walli & K. W. Bock: Differential induction of rat liver microsomal UDP-glucuronosyltransferase activities by various inducing agents. Biochem. Pharmacol. 1982, 31, 907-913.
    • (1982) Biochem. Pharmacol. , vol.31 , pp. 907-913
    • Lilienblum, W.1    Walli, A.K.2    Bock, K.W.3
  • 28
    • 71849104860 scopus 로고
    • Protein measurement with the Folin phenol reagent
    • Lowry, O., N. Rosebrough, L. Farr & R. Randall: Protein measurement with the Folin phenol reagent. J. Biol. Chem. 1951, 193, 265-275.
    • (1951) J. Biol. Chem. , vol.193 , pp. 265-275
    • Lowry, O.1    Rosebrough, N.2    Farr, L.3    Randall, R.4
  • 29
    • 0023035858 scopus 로고
    • Rat liver UDP-glucuronosyltransferase; sequence and expression of a cDNA encoding a phenobarbital inducible form
    • Mackenzie, P.: Rat liver UDP-glucuronosyltransferase; sequence and expression of a cDNA encoding a phenobarbital inducible form. J. Biol Chem. 1986, 261, 6119-6125.
    • (1986) J. Biol Chem. , vol.261 , pp. 6119-6125
    • Mackenzie, P.1
  • 30
    • 0027402335 scopus 로고
    • Glucuronidation of carcinogen metabolites by complementary DNA-expressed uridine 5′-diphosphate glucuronosyltransferases
    • Mackenzie, P. I., L. Rodbourn & T. Iyanagi: Glucuronidation of carcinogen metabolites by complementary DNA-expressed uridine 5′-diphosphate glucuronosyltransferases. Cancer Res. 1993, 53, 1529-1533.
    • (1993) Cancer Res. , vol.53 , pp. 1529-1533
    • Mackenzie, P.I.1    Rodbourn, L.2    Iyanagi, T.3
  • 31
    • 0020533372 scopus 로고
    • Revised methods for the Salmonella mutagenicity test
    • Maron, D. M. & B. N. Ames: Revised methods for the Salmonella mutagenicity test. Mut. Res. 1983, 113, 173-215.
    • (1983) Mut. Res. , vol.113 , pp. 173-215
    • Maron, D.M.1    Ames, B.N.2
  • 33
    • 0028181705 scopus 로고
    • Identification of 1-hydroxypyrene glucuronide as a major pyrene metabolite in human urine by synchronous fluorescence spectroscopy and gas chromatography-mass spectrometry
    • Strickland, P. T., D. Kang, E. D. Bowman, A. Fitzwilliam, T. E. Downing, N. Rothman, J. D. Groopman & A. Weston: Identification of 1-hydroxypyrene glucuronide as a major pyrene metabolite in human urine by synchronous fluorescence spectroscopy and gas chromatography-mass spectrometry. Carcinogenesis. 1994, 15, 483-487.
    • (1994) Carcinogenesis , vol.15 , pp. 483-487
    • Strickland, P.T.1    Kang, D.2    Bowman, E.D.3    Fitzwilliam, A.4    Downing, T.E.5    Rothman, N.6    Groopman, J.D.7    Weston, A.8
  • 34
    • 0025824236 scopus 로고
    • Purification and properties of a rat liver phenobarbital inducible 4-hydroxybiphenyl UDP-glucuronosyltransferase
    • Styczynski, P. M. Green, J. Puig, B. Coffman & T. Tephly: Purification and properties of a rat liver phenobarbital inducible 4-hydroxybiphenyl UDP-glucuronosyltransferase. Mol. Pharmacol. 1991, 40, 80-84.
    • (1991) Mol. Pharmacol. , vol.40 , pp. 80-84
    • Styczynski, P.1    Green, M.2    Puig, J.3    Coffman, B.4    Tephly, T.5
  • 36
    • 0028956177 scopus 로고
    • Potential genoprotective role for UDP-glucuronosyltransferases in chemical carcinogenesis: Initiation of micronuclei by benzo(a)pyrene and benzo(e-)pyrene in UDP-glucuronosyltransferase-deficient cultured rat skin fibroblasts
    • Vienneau, D. S., U. DeBoni & P. G. Wells: Potential genoprotective role for UDP-glucuronosyltransferases in chemical carcinogenesis: initiation of micronuclei by benzo(a)pyrene and benzo(e-)pyrene in UDP-glucuronosyltransferase-deficient cultured rat skin fibroblasts. Cancer Res. 1995, 55, 1045-1051.
    • (1995) Cancer Res. , vol.55 , pp. 1045-1051
    • Vienneau, D.S.1    DeBoni, U.2    Wells, P.G.3
  • 37
    • 0027448841 scopus 로고
    • Glucuronidation of steroid hormone in rat liver: Effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions
    • Visser, T. J., A. Kaptein, H. van Toor, J. A. van Raaij, K. J. van den Berg, C. T. Joe, J. G. van Engelen & A. Brouwer: Glucuronidation of steroid hormone in rat liver: effects of in vivo treatment with microsomal enzyme inducers and in vitro assay conditions. Endocrinology. 1993, 133, 2177-2186
    • (1993) Endocrinology , vol.133 , pp. 2177-2186
    • Visser, T.J.1    Kaptein, A.2    Van Toor, H.3    Van Raaij, J.A.4    Van Den Berg, K.J.5    Joe, C.T.6    Van Engelen, J.G.7    Brouwer, A.8
  • 38
    • 0018129450 scopus 로고
    • Demonstration of functional heterogeneity of hepatic uridine diphosphate glucuronosyltransferase activities after administration of 3-methylcholanthrene and phenobarbital to rats
    • Wishart, G. J.: Demonstration of functional heterogeneity of hepatic uridine diphosphate glucuronosyltransferase activities after administration of 3-methylcholanthrene and phenobarbital to rats. Biochem. J. 1978, 174, 671-672.
    • (1978) Biochem. J. , vol.174 , pp. 671-672
    • Wishart, G.J.1
  • 39
    • 0025058582 scopus 로고
    • Increase of a form of UDP-glucuronosyltransferase glucuronizing various phenolic xenobiotics and the corresponding translatable mRNA in 3-methylcholanthrene treated rat liver
    • Yokota, H. & A. Yuasa: Increase of a form of UDP-glucuronosyltransferase glucuronizing various phenolic xenobiotics and the corresponding translatable mRNA in 3-methylcholanthrene treated rat liver. J. Biochem. 1990, 107, 92-96.
    • (1990) J. Biochem. , vol.107 , pp. 92-96
    • Yokota, H.1    Yuasa, A.2


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