Early- and late-phase bronchoconstriction, airway hyper-reactivity and cell influx into the lungs, after 5′-adenosine monophosphate inhalation: Comparison with ovalbumin

Clinical and Experimental Allergy

Volumn 35, Issue 4, 2005, Pages 522-530

  Smith, N ^a   Johnson, F J ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Adenosine (5 amp); Bronchoconstriction; Conscious guinea pigs; Inflammatory cells; Late asthmatic response; Ovalbumin

Indexed keywords

ADENOSINE PHOSPHATE; ANTIGEN; HISTAMINE; OVALBUMIN;

AIRWAY CONDUCTANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BODY PLETHYSMOGRAPHY; BRONCHODILATATION; BRONCHOSPASM; BRONCHUS HYPERREACTIVITY; CELL INFILTRATION; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE COURSE; EOSINOPHIL; GUINEA PIG; INFLAMMATORY CELL; INHALATION; LEUKOCYTE DIFFERENTIAL COUNT; LUNG; LUNG LAVAGE; MACROPHAGE; MALE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROVOCATION TEST; SENSITIZATION;

ADENOSINE MONOPHOSPHATE; ADMINISTRATION, INHALATION; ANIMALS; ASTHMA; BRONCHI; BRONCHOCONSTRICTION; CELL COUNT; EOSINOPHILS; GUINEA PIGS; HISTAMINE; LUNG; MACROPHAGES; MALE; OVALBUMIN; RESPIRATORY SYSTEM;

EID: 17744398472     PISSN: 09547894     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2005.02211.x     Document Type: Article

References (32)

1. Barnes PJ, Chung KF, Page CP. Inflammatory mediators of asthma: an update. Pharmacol Rev 1998; 50:515-96.
2. Driver AG, Kukloy CA, Ali S, Mustafa SJ. Adenosine in bronchoalveolar lavage fluid in asthma. Am Rev Respir Dis 1993; 148:91-7.
3. Mann JS, Holgate ST, Renwick AG, Cushley MJ. Airway effects of purine nucleosides and release with bronchial provocation in asthma. J Appl Physiol 1986; 61:1667-76.
4. Cushley MJ, Tattersfield AE, Holgate ST. Inhaled adenosine and guanosine on airway resistance in normal and asthmatic subjects. Br J Clin Pharmacol 1983; 15:161-5.
5. Bjorck T, Gustafsson LE, Dahlen SE. Isolated bronchi from asthmatics are hyperresponsive to adenosine, which apparently acts indirectly by liberation of leukotrienes and histamine. Am Rev Respir Dis 1992; 145:1087-91.
6. Philips GD, Rafferty P, Beasley R, Holgate ST. Effect of oral terfenadine on the bronchoconstrictor responses to inhaled histamine and adenosine 5′ monophosphate in non-atopic asthma. Thorax 1987; 42:939-45.
7. Rafferty P, Beasley R, Southgate P, Holgate ST. The role of histamine and adenosine-induced bronchoconstriction. Int Arch Allergy Appl Immunol 1987; 82:292-4.
8. Spruntulis LM, Broadley KJ. A3 receptors mediate rapid inflammatory cell influx into the lungs of sensitised guinea pigs. Clin Exp Allergy 2001; 31:943-51.
9. Santing RE, Olymulder CG, Zaagsma J. Meurs H. Relationships among allergen-induced early and late phase airway obstructions, bronchial hyperreactivity, and inflammation in conscious unrestrained guinea pigs. J Allergy Clin Immunol 1994; 193:1021-30.
10. Danahay H, Broadley KJ. Effects of inhibitors of phosphodiesterase, on antigen-induced bronchial hyperreactivity in conscious sensitised guinea pigs and airway leukocyte infiltration. Br J Pharmacol 1997; 120:289-97.
11. Phillips GD, Holgate ST. Absence of a late-phase response or increase in histamine responsiveness after bronchial provocation with adenosine 5′-monophosphate in atopic and non-atopic asthma. Clin Sci 1988; 75:429-36.
12. Toward TJ, Broadley KJ. Early and late bronchoconstrictions, airway hyper reactivity, leucocyte influx and lung histamine and nitric oxide after inhaled antigen: effects of dexamethasone and rolipram. Clin Exp Allergy 2004; 34:91-102.
13. Toward TJ, Broadley KJ. Airway reactivity, inflammatory cell influx and nitric oxide in guinea pig airways after lippolysaccharide inhalation. Br J Pharmacol 2000; 131:271-81.
14. Griffiths-Johnson DA, Nicholls PJ, McDermott M. Measurement of specific airways conductance in guinea pigs: a non-invasive method. J Pharmacol Methods 1988; 19:233-48.
15. Finney NJ, Forsberg KI. Quantification of nasal involvement in a guinea pig plethysmograph. J Appl Physiol 1994; 76: 1432-8.
16. Schulung M, Zuidof AB, Meurs H, Zaagsma J. Role of tachykinin NK2-receptor activation in the allergen-induced late asthmatic reaction, airway hyperreactivity and airway inflammatory cell influx in conscious, unrestrained guinea-pigs. Br J Pharmacol 1999; 127:1030-8.
17. Santing RE, Schraa EO, Wachters A, Olymulder CG, Zaagsma J, Meurs H. Role of histamine in allergen-induced asthmatic reactions, bronchial hyperreactivity and inflammation in unrestrained guinea-pigs. Eur J Pharmacol 1994; 254:49-57.
18. Corrigan CJ, Kay AB. T cells and eosinophils in the pathogenesis of asthma. Immunol Today 1992; 13:501-6.
19. Durham SR, Kay AB. Eosinophils, bronchial hyperreactivity and late phase asthmatic reactions. Clin Allergy 1985; 15:411-8.
20. Hutson PA, Church MK, Miller TP, Holgate ST. Early and late phase bronchoconstriction after allergen challenge of nonaneasthetised guinea pigs. The association of disordered airway physiology to leukocyte infiltration. Am Rev Respir Dis 1988; 137:548-57.
21. De Boer J, Meurs H, Flendrig L, Koopal M, Zaagsma J. Role of nitric oxide and superoxide in allergen induced hyperreactivity after the late asthmatic reaction in guinea-pigs. Br J Pharmacol 2001; 133:1235-342.
22. Hargreave FE, Dolovich J, O'Byrne PM, Ramsdale EH, Daniel EE. The origin of airway hyperresponsiveness. J Allergy Clin Immunol 1986; 78:825-32.
23. 2 online 2004; 2:131p.
24. Thorne JR, Broadley KJ. Adenosine-induced bronchoconstriction of isolated lung and trachea from sensitised guinea-pigs. Br J Pharmacol 1992; 106:978-85.
25. Phillips GD, Scott VL, Richards R, Holgate ST. Effect of nedocromil sodium and sodium cromoglycate against bronchoconstriction induced by inhaled adenosine-5′-monophosphate. Eur Respir J 1989; 2:210-7.
26. Handley DA, Anderson AJ, Koester J, Snider ME. New millennium bronchodilators for asthma: single-isomer beta agonists. Curr Opin Pulm Med 2000; 6:43-9.
27. Ezeamuzie CI, Philips E. Adenosine A3 receptors on human eosinophils mediate inhibition of degranulation and superoxide anion release. Br J Pharmacol 1999; 27:188-94.
28. Feoktistov I, Biaggioni I. Adenosine A2B receptors. Pharmacol Rev 1997; 49:381-402.
29. Marquardt DL, Walker LL, Wasserman SI. Cromolyn inhibition of mediator release in mast cells derived from mouse bone marrow. Am Rev Respir Dis 1986; 133:1105-8.
30. Ghai G, Zimmerman MB, Hopkins MF. Evidence for A1 and A2 adenosine receptors in guinea pig trachea. Life Sci 1987; 41: 1215-24.
31. Losinski A, Alexander SPH. Adenosine receptor-mediated relaxation of guinea-pig precontracted isolated trachea. Br J Pharmacol 1995; 116:2425-8.
32. Fozard JR, Ellis KM, Dantas MFV, Tigani B, Mazzoni L. Effects of CGS 21680, a selective A (2A) receptor agonist, on allergic airways inflammation in the rat. Eur J Pharmacol 2002; 438:183-8.