Synthesis of selected LeY and KH-1 analogues: A medicinal chemistry approach to vaccine optimization

Journal of Organic Chemistry

Volumn 70, Issue 9, 2005, Pages 3383-3395

  Spassova, Maria K ^a   Bornmann, William G ^b   Ragupathi, Govindaswami ^a   Sukenick, George ^a   Livingston, Philip O ^a   Danishefsky, Samuel J ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODIES; ANTIGENS; BIOCHEMISTRY; CARBOHYDRATES; IMMUNIZATION; SYNTHESIS (CHEMICAL); TUMORS;

ANTIBODY TITER LEVELS; CARBOHYDRATE EPITOPES; GLYCALS; MEDICINAL CHEMISTRY;

VACCINES;

DRUG ANALOG; EPITOPE; KH 1 ANALOG; LEWIS Y ANALOG; TUMOR ANTIGEN; UNCLASSIFIED DRUG; ANTIGEN KH 1; ANTIGEN KH-1; CANCER VACCINE; IMMUNOLOGICAL ADJUVANT; LEWIS Y ANTIGEN; OLIGOSACCHARIDE; RECOMBINANT VACCINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BLOOD GROUP LEWIS SYSTEM; DRUG DESIGN; DRUG STRUCTURE; DRUG SYNTHESIS; GENE CONSTRUCT; IMMUNIZATION; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; VACCINE PRODUCTION; CARBOHYDRATE ANALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; IMMUNOLOGY; METHODOLOGY; SYNTHESIS;

ADJUVANTS, IMMUNOLOGIC; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; CANCER VACCINES; CARBOHYDRATE SEQUENCE; CHEMISTRY, PHARMACEUTICAL; IMMUNIZATION; LEWIS BLOOD-GROUP SYSTEM; MOLECULAR STRUCTURE; OLIGOSACCHARIDES; STRUCTURE-ACTIVITY RELATIONSHIP; VACCINES, SYNTHETIC;

EID: 17744386349     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo048016l     Document Type: Article

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