Direct writing of chitosan scaffolds using a robotic system

Rapid Prototyping Journal

Volumn 11, Issue 2, 2005, Pages 90-97

  Geng, Li ^a   Feng, Wei ^a   Hutmacher, Dietmar W ^a   Wong, Yoke San ^a   Loh, Han Tong ^a   Fuh, Jerry Y H ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Biotechnology; Rapid prototypes

Indexed keywords

BIOTECHNOLOGY; CELLS; COMPRESSION TESTING; COMPUTERIZED TOMOGRAPHY; GELS; HYDROGELS; ROBOTICS; SCAFFOLDS; SCANNING ELECTRON MICROSCOPY; TISSUE;

BIODEGRADABLE PROTEINS; CHITOSAN SCAFFOLDS; HYDROGEL SCAFFOLD; TISSUE ENGINEERING;

RAPID PROTOTYPING;

EID: 17744368883     PISSN: 13552546     EISSN: None     Source Type: Journal    
DOI: 10.1108/13552540510589458     Document Type: Article

References (28)

1. Ang, T.H. et al. (2002), "Fabrication of 3D chitosan-hydroxyaparite scaffolds using a robotic dispensing system", Mater. Sci. Eng. C, Vol. 20, pp. 35-42.
2. Endres, M., Hutmacher, D.W., Schantz, J.T., Kaps, C., Ringe, J., Salgado, A.J., Reis, R.L. and Sittinger, M. (2003), "Osteogenic induction of human bone marrow derived mesenchymal progenitor cells in novel synthetic polymer/hydrogel matrices", Tissue Engineering, Vol. 9 No. 4, pp. 689-702.
3. Giordano, R.A., Wu, B.M., Borland, S.W., Cima, L.G., Sachs, E.M. and Cima, M.J. (1996), "Mechanical properties of dense polylactic acid structures fabricated by three dimensional printing", Journal of Biomaterials (Science Polymer Edition), Vol. 8 No. 1, pp. 63-75.
4. Hollister, S.J., Levy, R.A., Chu, T.M.G., Halloran, J.W. and Feinberg, S.E. (2000), "An image based approach to design and manufacture craniofacial scaffolds", Int. J. Oral/Maxillofacial Surg., Vol. 29, pp. 67-71.
5. Hollister, S.J., Maddox, R.D. and Taboas, J.M. (2002), "Optimal design and fabrication of scaffolds to mimic tissue properties and satisfy biological constraints", Biomaterials, Vol. 23 No. 20, pp. 4095-103.
6. Huang, M.H., Li, S., Hutmacher, D.W., Schantz, J.T., Vacanti, J., Braud, C. and Vert, M. (2004), "Degradation and cell culture studies on block copolymers prepared by ring opening polymerization of ε-caprolactone in the presence of poly(ethylene glycol)", Journal of Biomedical Materials Research, Vol. 69A No. 3, pp. 417-27.
7. Hutmacher, D.W. (2000), "Polymeric scaffolds in tissue engineering bone and cartilage", Biomaterials, Vol. 21, pp. 2529-43.
8. Hutmacher, D.W., Sittinger, M. and Risbud, M.V. (2004), "Scaffold-based tissue engineering: rationale for computer-aided design and solid free-form fabrication systems", Trends Biotechnol., Vol. 22 No. 7, pp. 354-62.
9. Hutmacher, D.W., Teoh, S.H., Zein, I. and Tan, K.C. (2001), "Mechanical properties of polycaprolactone scaffolds fabricated using fused deposition modeling", Journal of Biomedical Materials Research Vol. 55, p. 1.
10. Kim, S.S., Utsunomiya, H., Koski, J.A., Wu, B.M., Cima, M.J., Sohn, J., Mukai, K., Griffith, L.G. and Vacanti, J.P. (1998), "Survival and function of hepatocytes on a novel three-dimensional synthetic biodegradable polymer scaffold with an intrinsic network of channels", Annals of Surgery, Vol. 228, pp. 8-13.
11. Lam, C.X.F., Mo, X.M., Teoh, S.H. and Hutmacher, D.W. (2002), "Scaffold development using 3D printing with a starch-based polymer", Mat. Sci. Eng. C-Bio S., Vol. 20, pp. 49-56.
12. Landers, R. and Mülhaupt, R. (2000), "Desktop manufacturing of complex objects, prototypes and biomedical scaffolds by means of computer-assisted design combined with computer-guided 3D plotting of polymers and reactive oligomers", Macromol. Mat. Eng., Vol. 282, pp. 17-21.
13. Landers, R. et al. (2002a), "Fabrication of soft tissue engineering scaffolds by means of rapid prototyping techniques", J. Mater. Sci., Vol. 37, pp. 3107-16.
14. Landers, R. et al. (2002b), "Rapid prototyping of scaffolds derived from thermoreversible hydrogels and tailored for applications in tissue engineering", Biomaterials, Vol. 23, pp. 4437-47.
15. Lewis et al. (2004), "Microperiodic structures: direct writing of three-dimensional webs", Nature, Vol. 428 No. 6981, p. 386.
16. Pfister, A. et al., (2004), "Biofunctional rapid prototyping for tissue-engineering applications: 3D bioplotting versus 3D printing", J. Polym. Sci. Part A: Polym. Chem., Vol. 42, pp. 624-38.
17. Porter, N.L., Pilliar, R.M. and Grynpas, M.D. (2001), "Fabrication of porous calcium polyphosphate implants by solid freeform fabrication: a study of processing and in vitro degradation characteristics", Journal of Biomedical Materials Research, Vol. 56, pp. 504-15.
18. Reece, G.P. and Patrick, C.W. Jr (1998), "Tissue engineered construct design principles", in Patrick, C.W. Jr, Mikos, A.G. and Mclntire, L.V. (Eds), Frontiers in Tissue Engineering, Elsevier Science Inc., New York, NY, pp. 166-96.
19. Sherwood, J.K., Riley, S.L., Palazzolo, R., Brown, S.C., Monkhouse, D.C., Coates, M., Griffith, L.G., Landeen, L.K. and Ratcliffe, A. (2002), "A three-dimensional osteochondral composite scaffold for articular cartilage repair", Biomaterials, Vol. 23 No. 24, pp. 4739-51.
20. Sultana, S.A. (2002), "Synthesis and characterization of chitosan-TCP 3D scaffolds for tissue engineering", Thesis for Bachelor Degree, Department of Mechanical Engineering, National University of Singapore, Singapore.
21. Sun, W. and Lal, P. (2002), "Recent development on computer aided tissue engineering: a review", Comput. Methods Programs Biomed., Vol. 67, pp. 85-103.
22. Tan, K.P. (2002), "Improvement of RPBOD system for multiple dispensing and application to tissue engineering", Thesis for Bachelor Degree, Department of Mechanical Engineering, National University of Singapore, Singapore.
23. Vozzi, G. et al. (2002), "Microsyringe-based deposition of two-dimensional and three-dimensional polymer scaffolds with a well-defined geometry for application to tissue engineering", Tissue Engineering, Vol. 8, pp. 1089-98.
24. Vozzi, G., Flaim, C., Ahluwalia, A. and Bhatia, S. (2003), "Fabrication of PLGA scaffolds using soft lithography and microsyringe deposition", Biomaterials, Vol. 24 No. 14, pp. 2533-40.
25. Williams, D. (1997), "Engineering a concept: the creation of tissue engineering", Med. Device Technol., Vol. 8 No. 10, pp. 8-9.
26. Wohlers, T. (2000), "Rapid prototyping and tooling state of the industry annual worldwide progress report", Wohlers Report 2000, Wohlers Associates, Inc., Fort Collins, CO.
27. Zeltinger, J., Sherwood, J.K., Graham, D.A., Mueller, R. and Griffith, L.G. (2001), "Effect of pore size and void fraction on cellular adhesion, proliferation and matrix deposition", Tissue Engineering, Vol. 7, pp. 557-71.
28. Zhang, Y. and Zhang, M. (2001), "Synthesis and characterization of macroporous chitosan/calcium phosphate composite scaffolds for tissue engineering", Journal of Biomedical Materials Research Vol. 55, pp. 304-12.