The effect of marker heterozygosity on the power to detect linkage disequilibrium

Genetics

Volumn 147, Issue 2, 1997, Pages 927-930

  Ott, Jurg ^a   Rabinowitz, Daniel ^b  

^a ROCKEFELLER UNIVERSITY   (United States)

^b Columbia University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ARTICLE; GENE LINKAGE DISEQUILIBRIUM; GENETIC ANALYSIS; GENETIC HETEROGENEITY; INHERITANCE; PRIORITY JOURNAL;

GENETIC MARKERS; HETEROZYGOTE; LINKAGE DISEQUILIBRIUM; MODELS, GENETIC;

EID: 0030827879     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Cox, D. R., and D. V. HINKLEY, 1974 Theoretical Statistics. Halsted Press, New York.
2. GOLDING, G. B., 1984 The sampling distribution of linkage disequilibrium. Genetics 108: 257-274.
3. HARTL, D. L., and A. G. CLARK, 1989 Principles of Population Genetics. Sinauer Associates, Sunderland, MA.
4. HUDSON, R. R., 1983 The sampling distribution of linkage disequilibrium under an infinite allele model without selection. Genetics 109: 611-631.
5. LEWONTIN, R. C., 1995 The detection of linkage disequilibrium in molecular sequence data. Genetics 140: 377-388.
6. TERWILLGER, J. D., Y. DING and J. OTT, 1992 On the relative importance of marker heterozygosity and intermarker distance in gene mapping. Genomics 13: 951-956.
7. THOMPSON, E. A., S. DEEB, D. WALKER and A. G. MOTULSKY, 1988 The detection of linkage disequilibrium between closely linked markers: RFLPs at the AI-CIII apolipoprotein genes. Am. J. Hum. Genet. 42: 113-124.
8. Visual Numerics, Inc., 1994 IMSL Fortran subroutines. Houston, TX.
9. WEIR, B. S., and C. C. COCKERHAM, 1978 Testing hypotheses about linkage disequilibrium with multiple alleles. Genetics 88: 633-642.
10. ZOUROS, E., G. B. GOLDING and T. F. C. MACKAY, 1977 The effect of combining alleles into electrophoretic classes on detecting linkage disequilibrium. Genetics 85: 543-556.