Crystal structures of the myristylated catalytic subunit of cAMP‐dependent protein kinase reveal open and closed conformations

Protein Science

Volumn 2, Issue 10, 1993, Pages 1559-1573

  Zheng, Jianhua ^a,c   Knighton, Daniel R ^a,d   Taylor, Susan S ^a   Xuong, Nguyen‐Huu ^a   Sowadski, Janusz M ^a   Eyck, Lynn F Ten ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ImmunoPharmaceutics Inc   (United States)

^d AGOURON PHARMACEUTICALS INC   (United States)

Author keywords

conformational changes; crystal structure; myristylation site; posttranslational modifications; protein kinases

Indexed keywords

ADENOSINE TRIPHOSPHATE; CYCLIC AMP DEPENDENT PROTEIN KINASE; INHIBITOR PROTEIN; PROTEIN SUBUNIT;

ANIMAL TISSUE; ARTICLE; COMPLEX FORMATION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; MYRISTYLATION; NONHUMAN; PROTEIN PHOSPHORYLATION; PROTEIN PROCESSING; PROTEIN QUATERNARY STRUCTURE; SWINE;

ANIMALIA; MAMMALIA; SUS SCROFA;

EID: 0027429591     PISSN: 09618368     EISSN: 1469896X     Source Type: Journal    
DOI: 10.1002/pro.5560021003     Document Type: Review

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