Antiretroviral agents and pregnancy: Mitochondrial dysfunction and nucleoside analogues;Antirétroviraux et grossesse: Cytopathie mitochondriale et analogues nucléosidiques

Therapie

Volumn 56, Issue 3, 2001, Pages 261-266

  Loubeyre Unique, C ^a   Gautier, A ^a   Vauzelle Gardier, C ^a   Champart, A M ^a   Bavoux, F ^a  

^a Centre Regional de Pharmacovigilance   (France)

Author keywords

Antiretroviral agents; Long term survey; Mitochondrial dysfunction; Newborn; Nucleoside reverse transcriptase inhibitors; Pregnancy

Indexed keywords

ANTIRETROVIRUS AGENT; MITOCHONDRIAL DNA; NUCLEOSIDE ANALOG; RNA DIRECTED DNA POLYMERASE INHIBITOR; ZIDOVUDINE;

CONFERENCE PAPER; DISORDERS OF MITOCHONDRIAL FUNCTIONS; FOLLOW UP; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; PREGNANCY; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; VERTICAL TRANSMISSION;

ADULT; ANIMALS; ANTIVIRAL AGENTS; DISEASE TRANSMISSION, VERTICAL; FEMALE; HIV INFECTIONS; HUMANS; INFANT; INFANT, NEWBORN; MITOCHONDRIA; MITOCHONDRIAL MYOPATHIES; NUCLEOSIDES; PREGNANCY; PREGNANCY COMPLICATIONS, INFECTIOUS; PRENATAL EXPOSURE DELAYED EFFECTS;

EID: 17644437091     PISSN: 00405957     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (41)

1. Reduction of maternal-infant transmission of human immunodeficiency virus type 1 with zidovudine treatment
2. Virus de l'immunodéfience humaine: Actualités en maternité
3. Perinatal HIV-1 transmission: Interaction between zidovudine prophylaxis and mode of delivery in the French perinatal cohort
4. Adverse effects of reverse transcriptase inhibitors: Mitochondrial toxicity as a common pathway
5. Hyperlactatemia and hepatic abnormalities in 10 human immunodeficiency virus-infected patients receiving nucleoside analogue combination regimens
6. Editorial response: Hyperlactatemia and hepatic steatosis as features of mitochondrial toxicity of nucleoside analogue reverse transcriptase inhibitors
7. Mitochondrial injury
8. Mitochondrial toxicity of antiviral drugs
9. Mitochondrial toxicity induced by nucleoside-analogue reverse-transcriptase inhibitors is a key factor in the pathogenesis of antiretroviral-therapy-related lipodystrophy
10. Manifestations neurologiques des maladies mitochondriales
11. Neonatal presentations of mitochondrial metabolic disorders
12. Developental changes in mitochondrial activity, and energy metabolism in fetal and neonatal rat brain
13. Riboflavine and severe lactic acidosis
14. A prospective study of infants born to women seropositive for human immunodeficiency virus type 1
15. Maternal factors associated with perinatal HIV-1 transmission: The French cohort study: 7 Years of follow-up observation
16. Persistent mitochondrial dysfunction and perinatal exposure to antiretroviral nucleoside analogues
17. Direction de l'Evaluation. Lettres aux prescripteurs
18. Vaginal epithelial DNA damage and expression of preneoplastic markers in mice during chronic dosing with tumorigenic levels of 3′-azido-2′, 3′-dideoxythymidine
19. Transplacental effects of 3′-azido-2′, 3′-dideoxythymidine (AZT): Tumorigenicity in mice and genotoxicity in mice and monkeys
20. Incorporation of zidovudine into leukocyte DNA from HIV-1 positive adults and pregnant women, and cord blood from infants exposed in utero
21. 3′-azido-3′deoxythymidine (AZT) transplacental perfusion kinetics and DNA incorporation in normal human placentas perfused with AZT
22. Genotoxic and functional consequences of transplacental zidovudine exposure in fetal monkey brain mitochondria
23. Fetal mitochondrial heart and skeletal muscle damage in erythrocebus patas monkeys exposed in utero to 3′-azido-3′-deoxythymidine
24. Effects of prenatal AZT on mouse neurobehavioral development and passive avoidance learning
25. Long-term effects of prenatal 3′ -azido-3′ deoxythymidine (AZT) exposure on intermale aggressive behaviour of mice
26. Profound anemia in a newborn infant of a mother receiving antiretroviral therapy
27. Severe transient neonatal lactic acidosis during prophylactic zidovudine treatment
28. Long-term antiretroviral combination therapy including lamivudine in HIV-1 infected women during pregnancy
29. Neonatal hypoperistalsis associated with perinatal zidovudine administration
30. Mitochondrial and peroxisomal dysfunction following perinatal exposure to antiretroviral drugs
31. Lack of long-term effects of in utero exposure to zidovudine among unifected children born to HIV-infected women
32. Drug safety during pregnancy and in infants: US cohort experience
33. Advances in research directions in the prevention of mother-to-child HIV-1 transmission
34. HIV-protease inhibitors
35. Antiretrovirals
36. DRESS (drug rash with eosinophilia and systemic symptoms) syndrome associated with nevirapine therapy
37. Severe hepatic failure related to nevirapine treatment