The Bartonella vinsonii subsp. arupensis immunodominant surface antigen BrpA gene, encoding a 382-kilodalton protein composed of repetitive sequences, is a member of a multigene family conserved among Bartonella species

Infection and Immunity

Volumn 73, Issue 5, 2005, Pages 3128-3136

  Gilmore Jr , Robert D ^a   Bellville, Travis M ^a,c   Sviat, Steven L ^a   Frace, Michael ^b  

^a NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

^b NATL CENTER FOR INFECTIOUS DISEASES   (United States)

^c UNIVERSITY OF VERMONT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADHESIN; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; BRPA PROTEIN; ISOPROTEIN; MEMBRANE ANTIGEN; OUTER MEMBRANE PROTEIN; PROTEIN BAD; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN RECOGNITION; ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BARTONELLA HENSELAE; BARTONELLA QUINTANA; BARTONELLA VINSONII; GENE EXPRESSION; GENE LIBRARY; GENETIC CODE; GENETIC CONSERVATION; HOST PARASITE INTERACTION; MOUSE; MULTIGENE FAMILY; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, BACTERIAL; ANTIGENS, SURFACE; BACTERIAL PROTEINS; BARTONELLA; BARTONELLA INFECTIONS; BASE SEQUENCE; BLOTTING, WESTERN; CONSERVED SEQUENCE; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; IMMUNODOMINANT EPITOPES; MICE; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; REPETITIVE SEQUENCES, NUCLEIC ACID; SEQUENCE ANALYSIS, DNA;

EID: 17644398488     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.73.5.3128-3136.2005     Document Type: Article

References (51)

1. Alleman, A. R., G. H. Palmer, T. C. McGuire, T. F. McElwain, L. E. Perryman, and A. F. Barbet. 1997. Anaplasma marginale major surface protein 3 is encoded by a polymorphic, multigene family. Infect. Immun. 65:156-163.
2. Alsmark, C. M., A. C. Frank, E. O. Karlberg, B. A. Legault, D. H. Ardell, B. Canback, A. S. Eriksson, A. K. Naslund, S. A. Handley, M. Huvet, B. La Scola, M. Holmberg, and S. G. Andersson. 2004. The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae. Proc. Natl. Acad. Sci. USA 101:9716-9721.
3. Anderson, B. E., G. A. McDonald, D. C. Jones, and R. L. Regnery. 1990. A protective protein antigen of Rickettsia rickettsii has tandemly repeated, near-identical sequences. Infect. Immun. 58:2760-2769.
4. Anderson, B. E., and M. A. Neuman. 1997. Bartonella spp. as emerging human pathogens. Clin. Microbiol. Rev. 10:203-219.
5. Bai, Y., M. Y. Kosoy, G. O. Maupin, K. R. Tsuchiya, and K. L. Gage. 2002. Genetic and ecologic characteristics of Bartonella communities in rodents in southern China. Am. J. Trop. Med. Hyg. 66:622-627.
6. Bermond, D., H. J. Boulouis, R. Heller, L. G. Van, H. Monteil, B. B. Chomel, A. Sander, C. Dehio, and Y. Piemont. 2002. Bartonella bovis sp. nov. and Bartonella capreoli sp. nov., isolated from European ruminants. Int. J. Syst. Evol. Microbiol. 52:383-390.
7. Bermond, D., R. Heller, F. Barrat, G. Delacour, C. Dehio, A. Alliot, H. Monteil, B. Chomel, H. J. Boulouis, and Y. Piemont. 2000. Bartonella birtlesii sp. nov., isolated from small mammals (Apodemus spp.). Int. J. Syst. Evol. Microbiol. 50:1973-1979.
8. Birtles, R. J., T. G. Harrison, and D. H. Molyneux. 1994. Grahamella in small woodland mammals in the U.K.: isolation, prevalence and host specificity. Ann. Trop. Med. Parasitol. 88:317-327.
9. Biswas, B., R. Vemulapalli, and S. K. Dutta. 1998. Molecular basis for antigenic variation of a protective strain-specific antigen of Ehrlichia risticii. Infect. Immun. 66:3682-3688.
10. Bown, K. J., M. Bennet, and M. Begon. 2004. Flea-borne Bartonella grahamii and Bartonella taylorii in bank voles. Emerg. Infect. Dis. 10:684-687.
11. Breitschwerdt, E. B., and D. L. Kordick. 2000. Bartonella infection in animals: carriership, reservoir potential, pathogenicity, and zoonotic potential for human infection. Clin. Microbiol. Rev. 13:428-438.
12. Carroll, J. A., S. A. Coleman, L. S. Smitherman, and M. F. Minnick. 2000. Hemin-binding surface protein from Bartonella quintana. Infect. Immun. 68:6750-6757.
13. Chang, C. C., B. B. Chomel, R. W. Kasten, R. M. Heller, H. Ueno, K. Yamamoto, V. C. Bleich, B. M. Pierce, B. J. Gonzales, P. K. Swift, W. M. Boyce, S. S. Jang, H. J. Boulouis, Y. Piemont, G. M. Rossolini, M. L. Riccio, G. Cornaglia, L. Pagani, C. Lagatolla, L. Selan, and R. Fontana. 2000. Bartonella spp. isolated from wild and domestic ruminants in North America. Emerg. Infect. Dis. 6:306-311.
14. Chang, C. C., B. B. Chomel, R. W. Kasten, V. Romano, and N. Tietze. 2001. Molecular evidence of Bartonella spp. in questing adult Ixodes pacificus ticks in California. J. Clin. Microbiol. 39:1221-1226.
15. Chung, C. Y., R. W. Kasten, S. M. Paff, B. A. Van Horn, M. Vayssier-Taussat, H. J. Boulouis, and B. B. Chomel. 2004. Bartonella spp. DNA associated with biting flies from California. Emerg. Infect. Dis. 10:1311-1313.
16. Coleman, S. A., and M. F. Minnick. 2001. Establishing a direct role for the Bartonella bacilliformis invasion-associated locus B (IalB) protein in human erythrocyte parasitism. Infect. Immun. 69:4373-4381.
17. Daly, J. S., M. G. Worthington, D. J. Brenner, C. W. Moss, D. G. Hollis, R. S. Weyant, A. G. Steigerwalt, R. E. Weaver, M. I. Daneshvar, and S. P. O'Connor. 1993. Rochalimaea elizabethae sp. nov. isolated from a patient with endocarditis. J. Clin. Microbiol. 31:872-881.
18. de la Fuente, J., J. C. Garcia-Garcia, E. F. Blouin, and K. M. Kocan. 2003. Characterization of the functional domain of major surface protein 1a involved in adhesion of the rickettsia Anaplasma marginale to host cells. Vet. Microbiol. 91:265-283.
19. Dehio, C., C. Lanz, R. Pohl, P. Behrens, D. Bermond, Y. Piemont, K. Pelz, and A. Sander. 2001. Bartonella schoenbuchii sp. nov., isolated from the blood of wild roe deer. Int. J. Syst. Evol. Microbiol. 51:1557-1565.
20. Freeland, R. L., D. T. Scholl, K. R. Rohde, L. J. Shelton, and K. L. O'Reilly. 1999. Identification of Bartonella-specific immunodominant antigens recognized by the feline humoral immune system. Clin. Diagn. Lab. Immunol. 6:558-566.
21. Greub, G., and D. Raoult. 2002. Bartonella: new explanations for old diseases. J. Med. Microbiol. 51:915-923.
22. Heller, R., M. Kubina, P. Mariet, P. Riegel, G. Delacour, C. Dehio, F. Lamarque, R. Kasten, H. J. Boulouis, H. Monteil, B. Chomel, and Y. Piemont. 1999. Bartonella alsatica sp. nov., a new Bartonella species isolated from the blood of wild rabbits. Int. J. Syst. Bacteriol. 49:283-288.
23. Heller, R., P. Riegel, Y. Hansmann, G. Delacour, D. Bermond, C. Dehio, F. Lamarque, H. Monteil, B. Chomel, and Y. Piemont. 1998. Bartonella tribocorum sp. nov., a new Bartonella species isolated from the blood of wild rats. Int. J. Syst. Bacteriol. 48:1333-1339.
24. Hinnebusch, B. J., A. G. Barbour, B. I. Restrepo, and T. G. Schwan. 1998. Population structure of the relapsing fever spirochete Borrelia hermsii as indicated by polymorphism of two multigene families that encode immunogenic outer surface lipoproteins. Infect. Immun. 66:432-440.
25. Hollingshead, S. K., V. A. Fischetti, and J. R. Scott. 1986. Complete nucleotide sequence of type 6 M protein of the group A Streptococcus. Repetitive structure and membrane anchor. J. Biol. Chem. 261:1677-1686.
26. Hollingshead, S. K., V. A. Fischetti, and J. R. Scott. 1987. Size variation in group A streptococcal M protein is generated by homologous recombination between intragenic repeats. Mol. Gen. Genet. 207:196-203.
27. Kosoy, M., M. Murray, R. D. Gilmore, Jr., Y. Bai, and K. L. Gage. 2003. Bartonella strains from ground squirrels are identical to Bartonella washoensis isolated from a human patient. J. Clin. Microbiol. 41:645-650.
28. Kosoy, M. Y., R. L. Regnery, O. I. Kosaya, and J. E. Childs. 1999. Experimental infection of cotton rats with three naturally occurring Bartonella species. J. Wildl. Dis. 35:275-284.
29. Kosoy, M. Y., R. L. Regnery, T. Tzianabos, E. L. Marston, D. C. Jones, D. Green, G. O. Maupin, J. G. Olson, and J. E. Childs. 1997. Distribution, diversity, and host specificity of Bartonella in rodents from the Southeastern United States. Am. J. Trop. Med. Hyg. 57:578-588.
30. Kosoy, M. Y., E. K. Saito, D. Green, E. L. Marston, D. C. Jones, and J. E. Childs. 2000. Experimental evidence of host specificity of Bartonella infection in rodents. Comp. Immunol. Microbiol. Infect. Dis. 23:221-238.
31. Lachenauer, C. S., R. Creti, J. L. Michel, and L. C. Madoff. 2000. Mosaicism in the alpha-like protein genes of group B streptococci. Proc. Natl. Acad. Sci. USA 97:9630-9635.
32. Litwin, C. M., T. B. Martins, and H. R. Hill. 1997. Immunologic response to Bartonella henselae as determined by enzyme immunoassay and Western blot analysis. Am. J. Clin. Pathol. 108:202-209.
33. McGill, S. L., R. L. Regnery, and K. L. Karem. 1998. Characterization of human immunoglobulin (Ig) isotype and IgG subclass response to Bartonella henselae infection. Infect. Immun. 66:5915-5920.
34. Mernaugh, G., and G. M. Ihler. 1992. Deformation factor: an extracellular protein synthesized by Bartonella bacilliformis that deforms erythrocyte membranes. Infect. Immun. 60:937-943.
35. Minnick, M. F., K. N. Sappington, L. S. Smitherman, S. G. Andersson, O. Karlberg, and J. A. Carroll. 2003. Five-member gene family of Bartonella quintana. Infect. Immun. 71:814-821.
36. Minnick, M. F., L. S. Smitherman, and D. S. Samuels. 2003. Mitogenic effect of Bartonella bacilliformis on human vascular endothelial cells and involvement of GroEL. Infect. Immun. 71:6933-6942.
37. Mitchell, S. J., and M. F. Minnick. 1995. Characterization of a two-gene locus from Bartonella bacilliformis associated with the ability to invade human erythrocytes. Infect. Immun. 63:1552-1562.
38. Pugsley, A. P. 1993. The complete general secretory pathway in gram-negative bacteria. Microbiol. Rev. 57:50-108.
39. Rakonjac, J. V., J. C. Robbins, and V. A. Fischetti. 1995. DNA sequence of the serum opacity factor of group A streptococci: identification of a fibronectin-binding repeat domain. Infect. Immun. 63:622-631.
40. Riess, T., S. G. Andersson, A. Lupas, M. Schaller, A. Schafer, P. Kyme, J. Martin, J. H. Walzlein, U. Ehehalt, H. Lindroos, M. Schirle, A. Nordheim, I. B. Autenrieth, and V. A. Kempf. 2004. Bartonella adhesin a mediates a proangiogenic host cell response. J. Exp. Med. 200:1267-1278.
41. Roux, V., S. J. Eykyn, S. Wyllie, and D. Raoult. 2000. Bartonella vinsonii subsp. berkhoffii as an agent of afebrile blood culture-negative endocarditis in a human. J. Clin. Microbiol. 38:1698-1700.
42. Scherer, D. C., I. DeBuron-Connors, and M. F. Minnick. 1993. Characterization of Bartonella bacilliformis flagella and effect of antiflagellin antibodies on invasion of human erythrocytes. Infect. Immun. 61:4962-4971.
43. Schmid, M. C., R. Schulein, M. Dehio, G. Denecker, I. Carena, and C. Dehio. 2004. The VirB type IV secretion system of Bartonella henselae mediates invasion, proinflammatory activation and antiapoptotic protection of endothelial cells. Mol. Microbiol. 52:81-92.
44. Schulein, R., and C. Dehio. 2002. The VirB/VirD4 type IV secretion system of Bartonella is essential for establishing intraerythrocytic infection. Mol. Microbiol. 46:1053-1067.
45. Smith, G. A., J. A. Theriot, and D. A. Portnoy. 1996. The tandem repeat domain in the Listeria monocytogenes ActA protein controls the rate of actin-based motility, the percentage of moving bacteria, and the localization of vasodilator-stimulated phosphoprotein and profilin. J. Cell Biol. 135:647-660.
46. Stevenson, H. L., Y. Bai, M. Y. Kosoy, J. A. Montenieri, J. L. Lowell, M. C. Chu, and K. L. Gage. 2003. Detection of novel Bartonella strains and Yersinia pestis in prairie dogs and their fleas (Siphonaptera: Ceratophyllidae and Pulicidae) using multiplex polymerase chain reaction. J. Med. Entomol. 40:329-337.
47. Sun, E. S., B. J. Molini, L. K. Barrett, A. Centurion-Lara, S. A. Lukehart, and W. C. Van Voorhis. 2004. Subfamily I Treponema pallidum repeat protein family: sequence variation and immunity. Microbes Infect. 6:725-737.
48. Walker, T. S., and H. H. Winkler. 1981. Bartonella bacilliformis: colonial types and erythrocyte adherence. Infect. Immun. 31:480-486.
49. Welch, D. F., K. C. Carroll, E. K. Hofmeister, D. H. Persing, D. A. Robison, A. G. Steigerwalt, and D. J. Brenner. 1999. Isolation of a new subspecies, Bartonella vinsonii subsp. arupensis, from a cattle rancher: identity with isolates found in conjunction with Borrelia burgdorferi and Babesia microti among naturally infected mice. J. Clin. Microbiol. 37:2598-2601.
50. Zhang, J. R., J. M. Hardham, A. G. Barbour, and S. J. Norris. 1997. Antigenic variation in Lyme disease borreliae by promiscuous recombination of VMP-like sequence cassettes. Cell 89:275-285.
51. Zhang, P., B. B. Chomel, M. K. Schau, J. S. Goo, S. Droz, K. L. Kelminson, S. S. George, N. W. Lerche, and J. E. Koehler. 2004. A family of variably expressed outer-membrane proteins (Vomp) mediates adhesion and autoaggregation in Bartonella quintana. Proc. Natl. Acad. Sci. USA 101:13630-13635.