Partitioning apoptosis: A novel form of the execution phase of apoptosis

Apoptosis

Volumn 10, Issue 1, 2005, Pages 219-231

  Zhang, B ^a   Arany, Z ^a,b   Mann, D ^a,b   Rhee, J G ^a,b   Fenton, R G ^a  

^a UNIVERSITY OF MARYLAND   (United States)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Caspase; Execution phase; Multiple myeloma; Programmed cell death

Indexed keywords

ACTIN; CASPASE; INTERLEUKIN 6; PROTEIN BCL 2; TUBULIN;

APOPTOSIS; ARTICLE; CELL NUCLEUS; CELL ORGANELLE; CELL STRUCTURE; CELL VACUOLE; CHROMATIN CONDENSATION; CONTROLLED STUDY; CYTOSKELETON; ELECTRON MICROSCOPY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; MULTIPLE MYELOMA; PRIORITY JOURNAL; RIBOSOME;

APOPTOSIS; CASPASES; CELL COMPARTMENTATION; CELLS, CULTURED; CHROMATIN; HUMANS; MICROSCOPY, ELECTRON; MULTIPLE MYELOMA;

EID: 17644393832     PISSN: 13608185     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10495-005-6077-4     Document Type: Article

References (41)

1. Johnstone RW, Ruefli AA, Lowe SW. Apoptosis: A link between cancer genetics and chemotherapy. Cell 2002; 108: 153-164.
2. Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000; 100: 57-70.
3. Arends MJ, Wyllie AH. Apoptosis: Mechanisms and roles in pathology. Int Rev Exp Pathol 1991; 32: 223-254.
4. Wyllie AH, Kerr JF, Currie AR. Cell death: The significance of apoptosis. Int Rev Cytol 1980; 68: 251-306.
5. Fadok VA, Bratton DL, Rose DM, Pearson A, Ezekewitz RA, Henson PM. A receptor for phosphatidylserine-specific clearance of apoptotic cells. Nature 2000; 405: 85-90.
6. Liu X, Zou H, Slaughter C, Wang X. DFF, a heterodimeric protein that functions downstream of caspase-3 to trigger DNA fragmentation during apoptosis. Cell 1997; 89: 175-184.
7. Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 1998; 391: 43-50.
8. Rao L, Perez D, White E. Lamm proteolysis facilitates nuclear events during apoptosis. J Cell Biol 1996; 135: 1441-1455.
9. Lee N, MacDonald H, Reinhard C, et al. Activation of hPAK65 by caspase cleavage induces some of the morphological and biochemical changes of apoptosis. Proc Natl Acad Sci USA 1997; 94: 13642-13647.
10. Rudel T, Bokoch GM. Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science 1997; 276: 1571-1574.
11. Kothakota S, Azuma T, Reinhard C, et al. Caspase-3-generated fragment of gelsolin: Effector of morphological change in apoptosis. Science 1997; 278: 294-298.
12. Zheng TS, Schlosser SF, Dao T, et al. Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo. Proc Natl Acad Sci USA 1998; 95: 13618-13623.
13. Janicke RU, Sprengart ML, Wati MR, Porter AG. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. J Biol Chem 1998; 273: 9357-9360.
14. Martin SJ, O'Brien GA, Nishioka WK, et al. Proteolysis of fodrin (non-erythroid spectrin) during apoptosis. J Biol Chem 1995; 270: 6425-6428.
15. Cotter TG, Lennon SV, Glynn JM, Green DR. Microfilament-disrupting agents prevent the formation of apoptotic bodies in tumor cells undergoing apoptosis [published erratum appears in Cancer Res 1992; 52(12): 3512]. Cancer Res 1992; 52: 997-1005.
16. Laster SM, Mackenzie JM, Jr. Bleb formation and F-actin distribution during mitosis and tumor necrosis factor-induced apoptosis. Microsc Res Tech 1996; 34: 272-280.
17. Mills JC, Stone NL, Erhardt J, Pittman RN. Apoptotic membrane blebbing is regulated by myosin light chain phosphorylation. J Cell Biol 1998; 140: 627-636.
18. Coleman ML, Sahai EA, Yeo M, Bosch M, Dewar A, Olson MF. Membrane blebbing during apoptosis results from caspase-mediated activation of ROCK I. Nat Cell Biol 2001; 3: 339-345.
19. Sebbagh M, Renvoize C, Hamelin J, Riche N, Bertoglio J, Breard J. Caspase-3-mediated cleavage of ROCK I induces MLC phosphorylation and apoptotic membrane blebbing. Nat Cell Biol 2001; 3: 346-352.
20. Zhang B, Gojo I, Fenton RG. Myeloid cell factor-1 is a critical survival factor for multiple myeloma. Blood 2002; 99: 1885-1893.
21. Jelinek DF. Mechanisms of myeloma cell growth control. Hematol Oncol Clin North Am 1999; 13: 1145-1157.
22. Klein B, Zhang XG, Jourdan M, et al. Paracrine rather than autocrine regulation of myeloma-cell growth and differentiation by interleukin-6. Blood 1989; 73: 517-526.
23. Gojo I, Zhang B, Fenton RG. The Cychn-dependent Kinase Inhibitor Flavopindol Induces Apoptosis in Multiple Myeloma Cells through Transcriptional Repression and Down-Regulation of Mcl-1. Clin Cancer Res 2002; 8: 3527-3538.
24. Vanags DM, Porn-Ares MI, Coppola S, Burgess DH, Orrenius S. Protease involvement in fodrin cleavage and phosphatidylserine exposure in apoptosis. J Biol Chem 1996; 271: 31075-31085.
25. Mills JC, Stone NL, Pittman RN. Extranuclear apoptosis. The role of the cytoplasm in the execution phase. J Cell Biol 1999; 146: 703-708.
26. Shimizu T, Cao CX, Shao RG, Pommier Y. Lamin B phosphorylation by protein kinase calpha and proteolysis during apoptosis in human leukemia HL60 cells. J Biol Chem 1998; 273: 8669-8674.
27. Henson PM, Bratton DL, Fadok VA. The phosphatidylserine receptor: A crucial molecular switch? Nat Rev Mol Cell Biol 2001; 2: 627-633.
28. Watters D, Waterhouse N. Proteolytic targets in cell death. Results Probl Cell Differ 1998; 24: 25-44.
29. Robertson JD, Orrenius S, Zhivotovsky B. Review: Nuclear events in apoptosis. J Struct Biol 2000; 129: 346-358.
30. Martelli AM, Zweyer M, Ochs RL, et al. Nuclear apoptotic changes: An overview. J Cell Biochem 2001; 82: 634-646.
31. Stolzenberg I, Wulf S, Mannherz HG, Paddenberg R. Different sublines of Jurkat cells respond with varying susceptibility of internucleosomal DNA degradation to different mediators of apoptosis. Cell Tissue Res 2000; 301: 273-282.
32. Faleiro L, Lazebnik Y. Caspases disrupt the nuclear-cytoplasmic barrier. J Cell Biol 2000; 151: 951-959.
33. Majno G, Joris I. Apoptosis, oncosis, and necrosis. An overview of cell death. Am J Pathol 1995; 146: 3-15.
34. Hirsch T, Marchetti P, Susin SA, et al. The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death. Oncogene 1997; 15: 1573-1581.
35. Leist M, Jaattela M. Four deaths and a funeral: From caspases to alternative mechanisms. Nat Rev Mol Cell Biol 2001; 2: 589-598.
36. Green DR, Reed JC. Mitochondria and apoptosis. Science 1998; 281: 1309-1312.
37. Leist M, Nicotera P. The shape of cell death. Biochem Biophys Res Commun 1997; 236: 1-9.
38. McCarthy NJ, Whyte MK, Gilbert CS, Evan GI. Inhibition of Ced-3/ICE-related proteases does not prevent cell death induced by oncogenes, DNA damage, or the Bcl-2 homologue Bak. J Cell Biol 1997; 136: 215-227.
39. Hoffmann PR, deCathelineau AM, Ogden CA, et al. Phosphatidylserine (PS) induces PS receptor-mediated macropinocytosis and promotes clearance of apoptotic cells. J Cell Biol 2001; 155: 649-659.
40. Somersan S, Bhardwaj N. Tethering and tickling: A new role for the phosphatidylserine receptor. J Cell Biol 2001; 155: 501-504.
41. Sauter B, Albert ML, Francisco L, Larsson M, Somersan S, Bhardwaj N. Consequences of cell death: Exposure to necrotic tumor cells, but not primary tissue cells or apoptotic cells, induces the maturation of immunostimulatory dendritic cells. J Exp Med 2000; 191: 423-434.