Crystal structure of Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase: Extreme asymmetry in a tetramer of identical subunits

Journal of Biological Chemistry

Volumn 280, Issue 15, 2005, Pages 14892-14899

  Dey, Sanghamitra ^a   Grant, Gregory A ^b   Sacchettini, James C ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CONFORMATIONS; CRYSTAL STRUCTURE; ENZYME INHIBITION; ESCHERICHIA COLI;

C-TERMINAL REGIONS; D-3-PHOSPHOGLYCERATE DEHYDROGENASE; MYCOBACTERIUM TUBERCULOSIS; NAD-BINDING SITE;

ENZYMES;

AMINO ACID; DEXTRO 3 PHOSPHOGLYCERATE DEHYDROGENASE; GLYCEROPHOSPHOLIPID; OXIDOREDUCTASE; SERINE; SOLVENT; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ESCHERICHIA COLI; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN MOTIF; PROTEIN STRUCTURE; SEQUENCE HOMOLOGY; STATISTICAL SIGNIFICANCE;

AMINO ACID MOTIFS; BINDING SITES; CARBOHYDRATE DEHYDROGENASES; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; LIGANDS; MODELS, MOLECULAR; MYCOBACTERIUM TUBERCULOSIS; PHOSPHOGLYCERATE DEHYDROGENASE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SOLVENTS;

ESCHERICHIA COLI; MYCOBACTERIUM; MYCOBACTERIUM TUBERCULOSIS;

EID: 17644385239     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M414489200     Document Type: Article

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