Activation of orbital and medial prefrontal cortex by methylphenidate in cocaine-addicted subjects but not in controls: Relevance to addiction

Journal of Neuroscience

Volumn 25, Issue 15, 2005, Pages 3932-3939

  Volkow, Nora D ^a,b   Wang, Gene Jack ^c   Ma, Yeming ^b   Fowler, Joanna S ^c   Wong, Christopher ^c   Ding, Yu Shin ^c   Hitzemann, Robert ^d   Swanson, James M ^e   Kalivas, Peter ^f  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

^b NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM   (United States)

^c BROOKHAVEN NATIONAL LABORATORY   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^e UNIVERSITY OF CALIFORNIA   (United States)

^f MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Cingulate gyrus; Dopamine; Imaging; Motivation; Orbitofrontal; Thalamus

Indexed keywords

CARBON 11; COCAINE; DOPAMINE; FLUORODEOXYGLUCOSE F 18; METHYLPHENIDATE; RACLOPRIDE;

ADULT; ARTICLE; BRAIN DEPTH STIMULATION; BRAIN FUNCTION; BRAIN METABOLISM; CLINICAL ARTICLE; COCAINE DEPENDENCE; COMPARATIVE STUDY; CONTROLLED STUDY; CORPUS STRIATUM; CORRELATION ANALYSIS; DOWN REGULATION; EMOTIONALITY; HUMAN; MALE; MOOD DISORDER; ORBITAL CORTEX; POSITRON EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; STATISTICAL SIGNIFICANCE; THALAMUS;

ADULT; BEHAVIOR, ADDICTIVE; BRAIN MAPPING; CARBON ISOTOPES; CENTRAL NERVOUS SYSTEM STIMULANTS; COCAINE-RELATED DISORDERS; DOPAMINE; DOPAMINE ANTAGONISTS; FLUORODEOXYGLUCOSE F18; FUNCTIONAL LATERALITY; HUMANS; MALE; METHYLPHENIDATE; POSITRON-EMISSION TOMOGRAPHY; PREFRONTAL CORTEX; RACLOPRIDE; STATISTICS;

EID: 17644375524     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.0433-05.2005     Document Type: Article

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