Compartmental modeling of transdermal iontophoretic transport: I. In vitro model derivation and application

Pharmaceutical Research

Volumn 21, Issue 11, 2004, Pages 1974-1984

  Nugroho, Akhmad Kharis ^a,b   Della Pasqua, Oscar ^a   Danhof, Meindert ^a   Bouwstra, Joke A ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

^b GADJAH MADA UNIVERSITY   (Indonesia)

Author keywords

Iontophoretic driving force; Post iontophoretic driving force; Skin release rate constant; Steady state flux; Time to achieve steady state flux

Indexed keywords

APOMORPHINE; PHOSPHATE BUFFERED SALINE; ROTIGOTINE; SURFACTANT; DOPAMINE RECEPTOR STIMULATING AGENT; SODIUM CHLORIDE;

ARTICLE; COMPARTMENT MODEL; DRUG DELIVERY SYSTEM; DRUG DIFFUSION; DRUG RELEASE; DRUG TRANSPORT; HUMAN; HUMAN TISSUE; IONTOPHORESIS; KINETICS; PARAMETER; PH; PRIORITY JOURNAL; STEADY STATE; STRATUM CORNEUM; ACTIVE TRANSPORT; ALGORITHM; DIFFUSION; IN VITRO STUDY; INTRADERMAL DRUG ADMINISTRATION; PHYSIOLOGY; SKIN ABSORPTION; STATISTICAL MODEL;

ADMINISTRATION, CUTANEOUS; ALGORITHMS; APOMORPHINE; BIOLOGICAL TRANSPORT, ACTIVE; DIFFUSION; DOPAMINE AGONISTS; HUMANS; HYDROGEN-ION CONCENTRATION; IONTOPHORESIS; KINETICS; MODELS, STATISTICAL; SKIN ABSORPTION; SODIUM CHLORIDE; SURFACE-ACTIVE AGENTS;

EID: 17644369029     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000048187.54125.ac     Document Type: Article

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