The structural comparison of the bacterial PepX and human DPP-IV reveals sites for the design of inhibitors of PepX activity

FEBS Journal

Volumn 272, Issue 8, 2005, Pages 2050-2059

  Rigolet, Pascal ^a   Xi, Xu Guang ^a   Rety, Stephane ^a   Chich, Jean François ^b  

^a Ecole Normale Superieure de Cachan   (France)

^b INRA Institut National de la Recherche Agronomique   (France)

Author keywords

Docking; DPP IV inhibitors; PepX; X prolyl dipeptidyl aminopeptidase

Indexed keywords

ALANINE; BACTERIAL ENZYME; DIPEPTIDE; PROLINE; UNCLASSIFIED DRUG; VALINE; X PROLYL DIPEPTIDYL AMINOPEPTIDASE;

AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SPECIFICITY; ENZYME STRUCTURE; HUMAN; LACTOCOCCUS LACTIS; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN ANALYSIS; STREPTOCOCCUS; STREPTOCOCCUS GORDONII;

ADENOSINE DEAMINASE; ANTIGENS, CD26; BINDING SITES; DIPEPTIDYL PEPTIDASES; DRUG DESIGN; EUKARYOTIC CELLS; GLYCOPROTEINS; HUMANS; LACTOCOCCUS LACTIS; MODELS, MOLECULAR; PROTEASE INHIBITORS; PROTEIN CONFORMATION; STREPTOCOCCUS; SUBSTRATE SPECIFICITY;

EID: 17444422824     PISSN: 1742464X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2005.04631.x     Document Type: Article

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